LOCUS BC000368 1901 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens phosphogluconate dehydrogenase, mRNA (cDNA clone
MGC:8331 IMAGE:2819330), complete cds.
ACCESSION BC000368
VERSION BC000368.2
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1901)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1901)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT On Nov 6, 2003 this sequence version replaced BC000368.1.
Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: DCTD/DTP
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 1 Row: a Column: 10
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 40068517.
FEATURES Location/Qualifiers
source 1..1901
/db_xref="H-InvDB:HIT000029558"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:8331 IMAGE:2819330"
/tissue_type="Lung, small cell carcinoma"
/clone_lib="NIH_MGC_7"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..1901
/gene="PGD"
/gene_synonym="6PGD"
/db_xref="GeneID:5226"
/db_xref="HGNC:HGNC:8891"
/db_xref="MIM:172200"
CDS 38..1489
/gene="PGD"
/gene_synonym="6PGD"
/codon_start=1
/product="phosphogluconate dehydrogenase"
/protein_id="AAH00368.1"
/db_xref="GeneID:5226"
/db_xref="HGNC:HGNC:8891"
/db_xref="MIM:172200"
/translation="MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLA
NEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGG
NSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGI
AAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQ
AFEDWNKTELDSFLIEITANILKFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGV
PVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKIIS
YAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLD
DFFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYF
GAHTYELLAKPGQFIHTNWTGHGGTVSSSSYNA"
BASE COUNT 469 a 481 c 515 g 436 t
ORIGIN
1 cgcgtcgccg ctcttcggtt ctgctctgtc cgccgccatg gcccaagctg acatcgcgct
61 gatcggattg gccgtcatgg gccagaactt aattctgaac atgaatgacc acggctttgt
121 ggtctgtgct tttaatagga ctgtctccaa agttgatgat ttcttggcca atgaggcaaa
181 gggaaccaaa gtggtgggtg cccagtccct gaaagagatg gtctccaagc tgaagaagcc
241 ccggcggatc atcctcctgg tgaaggctgg gcaagctgtg gatgatttca tcgagaaatt
301 ggtaccattg ttggatactg gtgacatcat cattgacgga ggaaattctg aatataggga
361 caccacaaga cggtgccgag acctcaaggc caagggaatt ttatttgtgg ggagcggagt
421 cagtggtgga gaggaagggg cccggtatgg cccatcgctc atgccaggag ggaacaaaga
481 agcgtggccc cacatcaaga ccatcttcca aggcattgct gcaaaagtgg gaactggaga
541 accctgctgt gactgggtgg gagatgaggg agcaggccac ttcgtgaaga tggtgcacaa
601 cgggatagag tatggggaca tgcagctgat ctgtgaggca taccacctga tgaaagacgt
661 gctgggcatg gcgcaggacg agatggccca ggcctttgag gattggaata agacagagct
721 agactcattc ctgattgaaa tcacagccaa tattctcaag ttccaagaca ccgatggcaa
781 acacctgctg ccaaagatca gggacagcgc ggggcagaag ggcacaggga agtggaccgc
841 catctccgcc ctggaatacg gcgtacccgt caccctcatt ggagaagctg tctttgctcg
901 gtgcttatca tctctgaagg atgagagaat tcaagctagc aaaaagctga agggtcccca
961 gaagttccag tttgatggtg ataagaaatc attcctggag gacattcgga aggcactcta
1021 cgcttccaag atcatctctt acgctcaagg ctttatgctg ctaaggcagg cagccaccga
1081 gtttggctgg actctcaatt atggtggcat cgccctgatg tggagagggg gctgcatcat
1141 tagaagtgta ttcctaggaa agataaagga tgcatttgat cgaaacccgg aacttcagaa
1201 cctcctactg gacgacttct ttaagtcagc tgttgaaaac tgccaggact cctggcggcg
1261 ggcagtcagc actggggtcc aggctggcat tcccatgccc tgttttacca ctgccctctc
1321 cttctatgac gggtacagac atgagatgct tccagccagc ctcatccagg ctcagcggga
1381 ttacttcggg gctcacacct atgaactctt ggccaaacca gggcagttta tccacaccaa
1441 ctggacaggc catggtggca ccgtgtcatc ctcgtcatac aatgcctgat catgctgctc
1501 ctgtcaccct ccacgattcc acagaccagg acattccatg tgcctcatgg cactgccacc
1561 tggccctttg ccctattttc tgttcagttt tttaaaagtg ttgtaagaga ctcctgagga
1621 agacacacag tttatttgta aagtagctct gtgagagcca ccatgccctc tgcccttgcc
1681 tcttgggact gaccaggagc tgctcatgtg cgtgagagtg ggaaccatct ccttgcggca
1741 gtggcttccg cgtgccccgt gtgctggtgc ggttcccatc acgcagacag gaagggtgtt
1801 tgcgcactct gatcaactgg aacctctgta tcatgcggct gaattccctt tttcctttac
1861 tcaataaaag ctacatcaca ctgaaaaaaa aaaaaaaaaa a
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