LOCUS BC000275 2114 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens cyclin-dependent kinase inhibitor 1A (p21, Cip1), mRNA
(cDNA clone MGC:3175 IMAGE:3355833), complete cds.
ACCESSION BC000275
VERSION BC000275.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2114)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2114)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2000) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Rubin Laboratory
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAL Plate: 6 Row: a Column: 4
This clone was selected for full length sequencing because it
passed the following selection criteria: Hexamer frequency ORF
analysis.
FEATURES Location/Qualifiers
source 1..2114
/db_xref="H-InvDB:HIT000029481"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:3175 IMAGE:3355833"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_16"
/lab_host="DH10B-R"
/note="Vector: pOTB7"
gene 1..2114
/gene="CDKN1A"
/gene_synonym="CAP20"
/gene_synonym="CIP1"
/gene_synonym="MDA-6"
/gene_synonym="P21"
/gene_synonym="p21CIP1"
/gene_synonym="SDI1"
/gene_synonym="WAF1"
/db_xref="GeneID:1026"
/db_xref="HGNC:HGNC:1784"
/db_xref="MIM:116899"
CDS 66..560
/gene="CDKN1A"
/gene_synonym="CAP20"
/gene_synonym="CIP1"
/gene_synonym="MDA-6"
/gene_synonym="P21"
/gene_synonym="p21CIP1"
/gene_synonym="SDI1"
/gene_synonym="WAF1"
/codon_start=1
/product="cyclin-dependent kinase inhibitor 1A (p21,
Cip1)"
/protein_id="AAH00275.1"
/db_xref="GeneID:1026"
/db_xref="HGNC:HGNC:1784"
/db_xref="MIM:116899"
/translation="MSEPAGDVRQNPCGSKACRRLFGPVDSEQLSRDCDALMAGCIQE
ARERWNFDFVTETPLEGDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALL
QGTAEEDHVDLSLSCTLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFS
KRKP"
BASE COUNT 418 a 627 c 571 g 498 t
ORIGIN
1 gttccttgtg gagccggagc tgggcgcgga ttcgccgagg caccgaggca ctcagaggag
61 gcgccatgtc agaaccggct ggggatgtcc gtcagaaccc atgcggcagc aaggcctgcc
121 gccgcctctt cggcccagtg gacagcgagc agctgagccg cgactgtgat gcgctaatgg
181 cgggctgcat ccaggaggcc cgtgagcgat ggaacttcga ctttgtcacc gagacaccac
241 tggagggtga cttcgcctgg gagcgtgtgc ggggccttgg cctgcccaag ctctaccttc
301 ccacggggcc ccggcgaggc cgggatgagt tgggaggagg caggcggcct ggcacctcac
361 ctgctctgct gcaggggaca gcagaggaag accatgtgga cctgtcactg tcttgtaccc
421 ttgtgcctcg ctcaggggag caggctgaag ggtccccagg tggacctgga gactctcagg
481 gtcgaaaacg gcggcagacc agcatgacag atttctacca ctccaaacgc cggctgatct
541 tctccaagag gaagccctaa tccgcccaca ggaagcctgc agtcctggaa gcgcgagggc
601 ctcaaaggcc cgctctacat cttctgcctt agtctcagtt tgtgtgtctt aattattatt
661 tgtgttttaa tttaaacacc tcctcatgta cataccctgg ccgccccctg ccccccagcc
721 tctggcatta gaattattta aacaaaaact aggcggttga atgagaggtt cctaagagtg
781 ctgggcattt ttattttatg aaatactatt taaagcctcc tcatcccgtg ttctcctttt
841 cctctctccc ggaggttggg tgggccggct tcatgccagc tacttcctcc tccccacttg
901 tccgctgggt ggtaccctct ggaggggtgt ggctccttcc catcgctgtc acaggcggtt
961 atgaaattca ccccctttcc tggacactca gacctgaatt ctttttcatt tgagaagtaa
1021 acagatggca ctttgaaggg gcctcaccga gtgggggcat catcaaaaac tttggagtcc
1081 cctcacctcc tctaaggttg ggcagggtga ccctgaagtg agcacagcct agggctgagc
1141 tggggacctg gtaccctcct ggctcttgat acccccctct gtcttgtgaa ggcaggggga
1201 aggtggggtc ctggagcaga ccaccccgcc tgccctcatg gcccctctga cctgcactgg
1261 ggagcccgtc tcagtgttga gccttttccc tctttggctc ccctgtacct tttgaggagc
1321 cccagctacc cttcttctcc agctgggctc tgcaattccc ctctgctgct gtccctcccc
1381 cttgtccttt cccttcagta ccctctcagc tccaggtggc tctgaggtgc ctgtcccacc
1441 cccaccccca gctcaatgga ctggaagggg aagggacaca caagaagaag ggcaccctag
1501 ttctacctca ggcagctcaa gcagcgaccg ccccctcctc tagctgtggg ggtgagggtc
1561 ccatgtggtg gcacaggccc ccttgagtgg ggttatctct gtgttagggg tatatgatgg
1621 gggagtagat ctttctagga gggagacact ggcccctcaa atcgtccagc gaccttcctc
1681 atccacccca tccctcccca gttcattgca ctttgattag cagcggaaca aggattcaga
1741 cattttaaga tggtggcagt agaggctatg gacagggcat gccacgtggg ctcatatggg
1801 gctgggagta gttgtctttc ctggcactaa cgttgagccc ctggaggcac tgaagtgctt
1861 agtgtacttg gagtattggg gtctgacccc aaacaccttc cagctcctgt aacatactgg
1921 cctggactgt tttctctcgg ctccccatgt gtcctggttc ccgtttctcc acctagactg
1981 taaacctctc gagggcaggg accacaccct gtactgttct gtgtctttca cagctcctcc
2041 cacaatgctg aatatacagc aggtgctcaa taaatgattc ttagtgactt taaaaaaaaa
2101 aaaaaaaaaa aaaa
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