LOCUS AY964668 1950 bp mRNA linear HUM 02-DEC-2005
DEFINITION Homo sapiens p53 and DNA damage-regulated IQ motif protein long
isoform (PIQ) mRNA, complete cds.
ACCESSION AY964668
VERSION AY964668.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1950)
AUTHORS Luo,X., He,Q., Huang,Y. and Sheikh,M.S.
TITLE Cloning and Characterization of a p53 and DNA Damage Down-regulated
Gene PIQ that Codes for a Novel Calmodulin-Binding IQ Motif Protein
and Is Up-regulated in Gastrointestinal Cancers
JOURNAL Cancer Res. 65 (23), 10725-10733 (2005)
PUBMED 16322217
REFERENCE 2 (bases 1 to 1950)
AUTHORS Luo,X., Huang,Y. and Sheikh,M.S.
TITLE Direct Submission
JOURNAL Submitted (16-MAR-2005) Pharmacology, SUNY Upstate Medical
University, 750 E. Adams St., Syracuse, NY 13210, USA
FEATURES Location/Qualifiers
source 1..1950
/db_xref="H-InvDB:HIT000333405"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
gene 1..1950
/gene="PIQ"
CDS 154..1950
/gene="PIQ"
/note="PIQ-L; interacts with calmodulin"
/codon_start=1
/product="p53 and DNA damage-regulated IQ motif protein
long isoform"
/protein_id="AAY46030.1"
/translation="MKPTGTDPRILSIAAEVAKSPEQNVPVILLKLKEIINITPLGSS
ELKKIKQDIYCYDLIQYCLLVLSQDYSRIQGGWTTISQLTQILSHCCVGLEPGEDAEE
FYNELLPSAAENFLVLGRQLQTCFINAAKAEEKDELLHFFQIVTDSLFWLLGGHVELI
QNVLQSDHFLHLLQADNVQIGSAVMMMLQNILQINSGDLLRIGRKALYSILDEVIFKL
FSTPSPVIRSTATKLLLLMAESHQEILILLRQSTCYKGLRRLLSKQETGTEFSQELRQ
LVGLLSPMVYQEVEEQKLHQAACLIQAYWKGFQTRKRLKKLPSAVIALQRSFRSKRSK
MLLEINRQKEEEDLKLQLQLQRQRAMRLSRELQLSMLEIVHPGQVEKHYREMEEKSAL
IIQKHWRGYRERKNFHQQRQSLIEYKAAVTLQRAALKFLAKCRKKKKLFAPWRGLQEL
TDARRVELKKRVDDYVRRHLGSPMSDVVSRELHAQAQERLQHYFMGRALEERAQQHRE
ALIAQISTNVEQLMKAPSLKEAEGKEPELFLSRSRPVAAKAKQAHLTTLKHIQAPWWK
KLGEESGDEIDVPKDELSIELENLFIGGTKPP"
BASE COUNT 643 a 382 c 463 g 462 t
ORIGIN
1 tgcggcgtgg gagccccagg ttctttagtg gaagaacgcg aagcgaggat gagtgatccg
61 tggaggcagt aacaggcgcg gcgagggaga agtgattccc gaagaatcaa ggctgggccg
121 gacccggtgg cctggcaaca ggtaataaga gaaatgaagc caacaggtac agacccaagg
181 atcttatcta tagctgctga agttgcaaaa agccctgagc agaatgtccc tgttatactg
241 ttgaagttaa aagaaataat aaacatcaca cctttaggaa gctcagagtt gaagaaaatc
301 aaacaagata tatattgtta tgatctcatt caatattgcc tcttggtcct cagtcaagat
361 tattctcgaa tccagggtgg ttggactaca atttcccagc ttacacagat attaagccat
421 tgctgtgtgg gcttggagcc aggagaagat gcagaggaat tttacaatga attacttcca
481 tcagctgcag aaaattttct agttttgggg agacaattac aaacatgttt tatcaatgca
541 gctaaggctg aagaaaaaga tgaattacta cactttttcc aaattgtgac tgattctctc
601 ttctggcttt tgggaggcca tgttgaactt attcagaatg tactacaaag tgatcatttc
661 ttacatttac tgcaagctga caatgtccaa ataggatctg cagtcatgat gatgctacag
721 aatatactac agatcaacag tggtgattta ctcagaatag gaagaaaagc cctgtattca
781 attttagatg aagttatttt caagcttttt tcaactccta gtccagttat aagaagtact
841 gctacaaaac tcctactgtt gatggctgaa tcccatcagg aaattttgat tttactgaga
901 caaagtacct gctacaaagg actcagacgt ctactaagta aacaggaaac tgggactgaa
961 ttcagtcaag aacttagaca gcttgttggc cttttaagcc caatggtcta tcaggaagta
1021 gaagagcaga aactacatca agcagcatgc ttgattcaag cctattggaa gggttttcag
1081 acaagaaaga gattaaagaa gcttccatct gctgtgattg ctttgcagag gagtttcaga
1141 tccaaacgat caaagatgtt gctggagata aataggcaga aggaagaaga ggacctcaaa
1201 ttacaattgc aacttcaaag acagagagcc atgagacttt cccgagaatt gcagctgagt
1261 atgctcgaaa tagttcatcc aggtcaggtg gagaaacact atcgggaaat ggaagagaaa
1321 tcagcactga ttatccagaa acattggaga gggtacaggg aaaggaaaaa ttttcaccaa
1381 cagaggcagt ctctcataga gtataaagca gctgtcacac ttcaaagagc agcgcttaaa
1441 ttcctagcga agtgccgtaa gaaaaagaaa ctatttgctc cttggcgagg actccaagaa
1501 ctcactgatg cacgccgagt tgaactgaag aaacgagtgg atgactatgt cagaagacat
1561 ttgggctctc caatgtcaga tgtggtcagt agggagctcc atgcccaagc tcaagaacga
1621 ctgcaacact actttatggg cagggcccta gaagagcgag cccagcagca cagagaagct
1681 ctgatagcac agatcagcac caacgttgaa cagctaatga aggcaccaag tctgaaggag
1741 gcagaaggga aagaacctga gctcttccta agtagatcca ggcctgtggc agccaaggcc
1801 aagcaggccc atctcacaac cctgaagcac atacaagcac cctggtggaa gaagcttgga
1861 gaagaatctg gagatgagat tgatgttcca aaggatgagc ttagtataga attagaaaat
1921 ttattcattg gtggaaccaa accaccttag
//