LOCUS AY894755 4420 bp mRNA linear HUM 11-DEC-2007
DEFINITION Homo sapiens proteasome activator 200 kDa iii (PSME4) mRNA,
complete cds, alternatively spliced.
ACCESSION AY894755
VERSION AY894755.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4420)
AUTHORS Blickwedehl,J., McEvoy,S., Wong,I., Kousis,P., Clements,J.,
Elliott,R., Cresswell,P., Liang,P. and Bangia,N.
TITLE Proteasomes and proteasome activator 200 kDa (PA200) accumulate on
chromatin in response to ionizing radiation
JOURNAL Radiat. Res. 167 (6), 663-674 (2007)
PUBMED 17523843
REFERENCE 2 (bases 1 to 4420)
AUTHORS Blickwedehl,J., McEvoy,S., Wong,I., Kousis,P., Cresswell,P.,
Liang,P. and Bangia,N.
TITLE Direct Submission
JOURNAL Submitted (17-JAN-2005) Immunology, Roswell Park Cancer Institute,
Elm and Carlton Streets, Buffalo, NY 14263, USA
FEATURES Location/Qualifiers
source 1..4420
/db_xref="H-InvDB:HIT000332527"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2p16.3"
/cell_line="KG1"
gene 1..4420
/gene="PSME4"
/gene_synonym="PA200"
CDS 313..3276
/gene="PSME4"
/gene_synonym="PA200"
/note="PA200iii; alternatively spliced"
/codon_start=1
/product="proteasome activator 200 kDa iii"
/protein_id="AAX83870.1"
/translation="MGENLAKKIMFFLLIIRKLLNHILDNSEDDTKSLFLIIKIIGDL
LQFQGSHKHEFDSRWKSFNLVKKSMENRLHGKKQHIRALLIDRVMLQHELRTLTVEGC
EYKKIHQDMIRDLLRLSTSSYSQVRNKAQQTFFAALGAYNFCCRDIIPLVLEFLRPDR
QGVTQQQFKGALYCLLGNHSGVCLANLHDWDCIVQTWPAIVSSGLSQAMSLEKPSIVR
LFDDLAEKIHRQYETIGLDFTIPKSCVEIAELLQQSKNPSINQILLSPEKIKEGIKRQ
QEKNADALRNYENLVDTLLDGVEQRNLPWKFEHIGIGLLSLLLRDDRVLPLRAIRFFV
ENLNHDAIVVRKMAISAVAGILKQLKRTHKKLTINPCEISGCPKPTQIIAGDRPDNHW
LHYDSKTIPRTKKEWESSCFVEKTHWGYYTWPKNMVVYAGVEEQPKLGRSREDMTEAE
QIIFDHFSDPKFVEQLITFLSLEDRKGKDKFNPRRFCLFKGIFRNFDDAFLPVLKPHL
EHLVADSHESTQRCVAEIIAGLIRGSKHWTFEKVEKLWELLCPLLRTALSNITVETYN
DWGACIATSCESRDPRKLHWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVP
ELLHRLLKYLEPKLTQVYKNVRERIGSVLTYIFMIDVSLPNTTPTISPHVPEFTARIL
EKLKPLMDVDEEIQNHVMEENGIGEEDERTQGIKLLKTILKWLMASAGRSFSTAVTEQ
LQLLPLFFKIAPVENDNSYDELKRDAKLCLSLMSQGLLYPHQVPLVLQVLKQTARSSS
WHARYTVLTYLQTMVFYNLFIFLNNEDAVKDIRWLVISLLEDEQLEVREMAATTLSGL
LQCNFLTMDSPMQIHFEQLCKTKLPKKRKRDPGSVGDTIPSAELVKRHAGVLGLGACV
LSSPYDVPTWMPQLLMNLSAHLNDPQPIEMTVKKTLSNFRRTHHDNWQEHKQQFTDDQ
LLVLTDLLVSPCYYA"
BASE COUNT 1292 a 872 c 982 g 1274 t
ORIGIN
1 ggtgggggcc ggggagggtt cgggtgggag ggggtggggg gggtgtccct gggctcatgg
61 agccggccga gcgggcggga gtcggagagc ccccggagcc gggcgggcgt cccgagccgg
121 gcccgcgggg cttcgtcccg cagaaggaga tcgtctacaa caagctgctg ccctacgcgg
181 agcggctaga cgccgagtcc gacttgcagc tggcccagat caaatgcaac ctgggccggg
241 ccgtgcagct ccaagagctg tggcccgggg gcctcttctg gaccaggaaa ctctccacat
301 atattcgact ttatgggaga aaatttagca aagaagatca tgttcttttt attaattata
361 aggaaacttc ttaaccacat acttgataat tcagaagatg atactaagtc attgtttctt
421 attataaaga ttattggaga ccttttacaa ttccaaggat ctcacaagca tgaatttgac
481 tcccgatgga aaagcttcaa cttagtaaag aaatcaatgg aaaatcggct ccatgggaaa
541 aaacaacata tcagagcact gttgattgat agagtaatgt tacagcatga gctacggaca
601 ctaactgttg agggttgtga atacaaaaag atacatcaag atatgatcag agatcttctt
661 cgtttatcta caagttcata cagtcaggtg agaaataagg ctcagcaaac attttttgct
721 gccttgggag catataactt ctgttgcaga gatatcattc ccttggtttt ggagttctta
781 aggcctgata gacaaggtgt tacacagcaa caattcaagg gtgccttgta ctgtctcctt
841 ggaaatcaca gtggtgtgtg cttggcaaac cttcatgatt gggactgtat tgtacagacg
901 tggccagcga ttgtttcttc agggcttagc caagcaatgt ccctggaaaa gccatcaata
961 gtgagattgt ttgatgatct tgcagaaaag attcataggc agtatgaaac aattggcttg
1021 gacttcacaa ttccaaagtc atgtgttgaa atagcggaat tacttcaaca gtcaaaaaac
1081 ccctctatca accagatatt gcttagccca gaaaaaatta aggaaggaat taaacgccaa
1141 caggaaaaga atgccgatgc cctaaggaac tatgaaaatt tggtagacac cttgctagat
1201 ggtgtggagc aaagaaacct gccctggaaa tttgaacata taggcattgg gcttctgtct
1261 ctactgctga gagatgaccg agtgttgcct cttcgtgcca tacggttttt tgttgagaat
1321 ctcaaccatg atgcaattgt agttcgaaag atggctatct cagctgttgc tggtatcctt
1381 aaacagctaa aaagaaccca caaaaagctg accattaacc cctgtgaaat cagtggatgc
1441 cctaaaccca cccaaattat tgctggtgat aggcctgata atcattggtt gcattatgac
1501 agcaaaacta taccaagaac taaaaaagaa tgggagtcaa gttgctttgt ggaaaaaact
1561 cactggggat actacacctg gccaaagaat atggttgttt atgctggtgt ggaagagcag
1621 cctaagcttg gcagaagcag ggaggatatg acagaggcag aacagattat atttgatcat
1681 ttttctgatc ctaaatttgt tgagcagtta attacttttc tatcattaga agacagaaaa
1741 ggaaaagata agtttaatcc acgacgtttt tgcctcttta agggtatatt caggaatttt
1801 gatgatgcct tcctgccagt tctgaagccc catttagaac atttggttgc agattcacat
1861 gaaagcaccc agcgatgtgt tgcagaaatt atagctggtt taatcagagg ttctaagcac
1921 tggacatttg aaaaggtgga gaagctttgg gagcttctgt gccctctgct tagaacagca
1981 ctgtccaata ttaccgtaga aacttataat gactggggag cttgtatagc aacatcctgt
2041 gaaagcagag atccccggaa acttcactgg ctttttgaac tgctgttgga atcaccattg
2101 agtggtgaag gaggatcctt tgtagatgca tgtcgacttt atgtactaca aggtggcctt
2161 gcccagcaag aatggagagt gcctgaacta ttgcacagac tactgaagta cttggaaccc
2221 aaactcaccc aggtttacaa aaatgtcaga gaaagaatag gaagtgtgct gacctacata
2281 ttcatgatag atgtatcttt gccaaatacc acaccaacca tatcgcctca tgtccctgag
2341 tttactgctc gaattctgga gaaattgaaa cctctcatgg atgtggatga agaaattcag
2401 aaccatgtta tggaagaaaa tggaattggt gaagaagatg agcgaactca gggcattaaa
2461 ctcttgaaaa ccatattgaa atggctgatg gcaagtgcag gaagatcctt ttctacagca
2521 gttacagaac aacttcagct tctacctttg tttttcaaga ttgccccagt ggaaaatgac
2581 aatagctacg atgaactgaa aagagatgca aagttatgtt tatcattaat gtctcagggg
2641 ttgctttacc ctcatcaagt gcctttggta cttcaggtgc taaaacaaac agcaagaagc
2701 agttcttggc atgcacgata cacagtactg acctacctcc agaccatggt attttataac
2761 ctctttattt tcctaaacaa tgaagatgca gttaaagata tcaggtggct ggttataagt
2821 cttttggagg acgaacaact ggaggttcga gaaatggctg ctactacctt aagcggtctg
2881 ctacagtgta actttcttac catggacagt cctatgcaga ttcattttga gcaactttgc
2941 aaaacaaaac tacctaagaa aagaaagcga gaccctggtt ctgtaggaga taccattcct
3001 tctgcagagt tggtcaaacg ccatgctggg gtgctaggac ttggtgcatg tgttctttct
3061 agtccttacg atgttcccac ctggatgccc cagctcctca tgaatctcag tgcacatcta
3121 aatgatcctc agcctattga gatgactgta aaaaaaacct tatccaattt ccgaaggact
3181 caccatgaca actggcagga acataaacag caattcactg atgaccaact gcttgttctc
3241 accgatcttc ttgtgtcacc atgctattat gcatagaaag atgactagtc ctcacttcag
3301 gctcttttca tcaaaaattc cacaccctca ggtaccatct gtggtggctc tctgcaagtt
3361 ttaaaactgc ctctgctgag ctctcatcat tttggtggtt tctgtgttag atctcgttag
3421 tctgcattcc acagcttctc agttgccatt tgatttccca acttgtccgg aagtgtttcc
3481 agaatactga tcactttttt tttttgaggc atctgacaaa gtcacaaagt ctcagactag
3541 aaataattac ccagtatgat catggcatcc aagaccagag tctcagaact cattaagaaa
3601 cagtttactt ggaatggaga atacccatct gtaatacagg tcctgtcatt tcattcatct
3661 caaattattt tgaattcttc ccaaatggct gctggattta ggtggtaata ggggctgtgg
3721 gccataaatc tgaagccttg agaaccttgg gtctggagag ccatgaagag ggaaggaaaa
3781 gagggcaagt cctgaaccta accaatgacc tgatggattg ctcgaccaag acacagaagt
3841 gaagtctgtg tctgtgcact tcccacagac tggagttttt ggtgctgaat agagccagtt
3901 gctaaaaaat tgggggtttg gtgaagaaat ctgattgttg tgtgtattca atgtgtgatt
3961 ttaaaaataa acagcaacaa caataaaaac cctgactggc tgttttttcc ctgtattctt
4021 tacaactatt ttttgaccct ctgaaaatta ttatacttca cctaaatgga agactgctgt
4081 gtttgtggaa attttgtaat tttttaattt attttattct ctctcccttt ttattttgcc
4141 tgcagaatcg ttgagagact aataaggctt aatatttaat tgatttgttt aatatgttat
4201 ataaatgtaa aagagtgtat aaactgtaga gatagcattg gcaagacatt gtacagatgc
4261 aaccttttac acaacatcat tgtgtaattt gtaaagattc acgtgtagtt ctttattata
4321 gtgattttgg gctttgtacc cactgaatgc cattttttgt gtttttaaat tattttcttt
4381 atcttgttac aaaaactgag atgtggggtt tttttttttt
//