LOCUS AY858556 1910 bp mRNA linear HUM 28-SEP-2007
DEFINITION Homo sapiens RAS guanyl releasing protein I splice variant B mRNA,
complete cds, alternatively spliced.
ACCESSION AY858556
VERSION AY858556.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1910)
AUTHORS Yasuda,S., Stevens,R.L., Terada,T., Takeda,M., Hashimoto,T.,
Fukae,J., Horita,T., Kataoka,H., Atsumi,T. and Koike,T.
TITLE Defective expression of Ras guanyl nucleotide-releasing protein 1
in a subset of patients with systemic lupus erythematosus
JOURNAL J. Immunol. 179 (7), 4890-4900 (2007)
PUBMED 17878389
REFERENCE 2 (bases 1 to 1910)
AUTHORS Yasuda,S., Atsumi,T. and Koike,T.
TITLE Novel splice variant of hRasGRP1
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 1910)
AUTHORS Yasuda,S., Atsumi,T. and Koike,T.
TITLE Direct Submission
JOURNAL Submitted (08-DEC-2004) Medicine II, Hokkaido University Graduate
School of Medicine, N15, W7, Kita-ku, Sapporo 060-8648, Japan
REFERENCE 4 (bases 1 to 1910)
AUTHORS Yasuda,S., Atsumi,T. and Koike,T.
TITLE Direct Submission
JOURNAL Submitted (27-FEB-2007) Medicine II, Hokkaido University Graduate
School of Medicine, N15, W7, Kita-ku, Sapporo 060-8648, Japan
REMARK Sequence update by submitter
COMMENT On Feb 27, 2007 this sequence version replaced AY858556.1.
FEATURES Location/Qualifiers
source 1..1910
/db_xref="H-InvDB:HIT000257906"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="15"
/map="15q15"
CDS 8..1801
/note="hRasGRP1; alternatively spliced"
/codon_start=1
/product="RAS guanyl releasing protein I splice variant B"
/protein_id="AAW32406.2"
/translation="MGTLGKAREAPRKPSHGCRAASKARLEAKPANSPFPSHPSLAHI
TQFRMMVSLGHLAKGASLDDLIDSCIQSFDADGNLCRSNQLLQVMLTMHRIVISSAEL
LQKVITLYKDALAKNSPGLCLKICYFVRYWITEFWVMFKMDASLTDTMEEFQELVKAK
GEELHCRLIDTTQINARDWSRKLTQRIKSNTSKKRKVSLLFDHLEPEELSEHLTYLEF
KSFRRISFSDYQNYLVNSCVKENPTMERSIALCNGISQWVQLMVLSRPTPQLRAEVFI
KFIQVAQKLHQLQNFNTLMAVIGGLCHSSISRLKETSSHVPHEINKVLGEMTELLSSS
RNYDNYRRAYGECTDFKIPILGVHLKDLISLYEAMPDYLEDGKVNVHKLLALYNHISE
LVQLQEVAPPLEANKDLVHLLTLSLDLYYTEDEIYELSYAREPRNHRAPSVFKNYDHD
QDGYISQEEFEKIAASFPFSFCVMDKDREGLISRDEITAYFMRASSIYSKLGLGFPHN
FQETTYLKPTFCDNCAGFLWGVIKQGYRCKDCGMNCHKQCKDLVVFECKKRAKNPVAP
TENNTSVGPVSNLCSLGAKDLLHGNKYSESR"
BASE COUNT 539 a 483 c 443 g 445 t
ORIGIN
1 cgcggccatg ggcaccctgg gcaaggcgag agaggctccg cggaaacctt cccatggctg
61 cagagctgcc tctaaagcaa gactagaggc aaagccagcc aacagcccct tcccctccca
121 tcccagcttg gcccacatca cccagttccg aatgatggtg tctctgggac atttagccaa
181 aggagccagc ctggacgatc tcattgacag ctgcattcaa tcttttgatg cagatggaaa
241 cctgtgtcga agtaaccaac tgttgcaagt catgctgacc atgcaccgaa ttgtcatctc
301 ctctgcagaa ctgctccaaa aagttatcac cctctataag gatgctttgg caaagaattc
361 accaggactt tgcctgaaga tctgttattt tgtaaggtat tggataacag aattctgggt
421 catgtttaaa atggacgcca gcttgacaga cactatggag gagtttcagg aactggtgaa
481 ggctaagggt gaggagttac attgccgcct gattgacaca actcaaatca atgcccgtga
541 ctggtccagg aaacttactc aaaggataaa atcaaatacc agcaagaaac ggaaagtctc
601 cctgctcttt gaccatctgg aaccagaaga gctatccgag cacctcacct accttgagtt
661 caagtctttc cggaggatat cgttctctga ttatcagaat taccttgtaa atagctgtgt
721 gaaggaaaac cccaccatgg agcgatctat tgctctgtgc aacggcatct cccagtgggt
781 acaactgatg gttctcagcc gccccacgcc gcagctccga gcagaagtct tcatcaagtt
841 catccaggtg gctcagaagc tccaccaact acagaacttc aatacactga tggctgtgat
901 aggtgggctg tgtcacagct caatctcgag gctcaaggag acaagttcgc atgtcccaca
961 tgaaatcaat aaggttctcg gtgagatgac tgagctgctg tcctcctcca gaaactacga
1021 caattaccgg cgagcctatg gagagtgcac cgacttcaag atccccattc tgggtgtgca
1081 tctcaaggac ctcatctccc tgtatgaagc catgcctgac tatctggagg acgggaaagt
1141 gaacgtccat aagctactgg ccctatacaa tcatatcagt gaattggtcc agctgcaaga
1201 ggtggcccca cccttggagg ctaacaagga cttggtacac ttgctgacgt tatccctgga
1261 tctttactac actgaggatg aaatctatga gctttcctat gcccgggaac caaggaacca
1321 cagagctcca tctgtcttca agaactatga tcacgaccag gatggataca tttctcagga
1381 agaatttgaa aagattgctg cgagttttcc attttccttc tgtgtgatgg acaaagacag
1441 ggaaggcctc atcagcaggg atgagatcac agcctacttc atgagagcca gctcaatcta
1501 ttccaagctg ggcctgggct ttcctcacaa cttccaagag accacctacc tgaagcccac
1561 tttttgtgac aactgtgctg gatttctctg gggagtgatc aaacaaggat atcgatgtaa
1621 agactgcggg atgaactgtc acaaacaatg caaagatctg gttgtgtttg agtgtaagaa
1681 gcgagccaag aacccagtag ctcccacaga gaacaacact tctgtggggc cagtgtccaa
1741 cctttgctca ttgggagcca aagacctgct ccatggaaat aaatactctg aaagcagata
1801 atgatgccct aaagatccaa ctgaaatatg cacagaagaa aatagaatcc ctccagcttg
1861 aaaaaagcaa tcatgtctta gctcaaatgg agcagggtga ctgttcttag
//