LOCUS AY847302 1578 bp mRNA linear HUM 29-MAY-2005
DEFINITION Homo sapiens P2X7 isoform F (P2RX7) mRNA, complete cds,
alternatively spliced.
ACCESSION AY847302
VERSION AY847302.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1578)
AUTHORS Cheewatrakoolpong,B., Gilchrest,H., Anthes,J.C. and Greenfeder,S.
TITLE Identification and characterization of splice variants of the human
P2X7 ATP channel
JOURNAL Biochem. Biophys. Res. Commun. 332 (1), 17-27 (2005)
PUBMED 15896293
REMARK Erratum:[Biochem Biophys Res Commun. 2006 Mar 14;342(3):1004]
REFERENCE 2 (bases 1 to 1578)
AUTHORS Cheewatrakoolpong,B., Gilchrest,H., Anthes,J.C. and Greenfeder,S.
TITLE Direct Submission
JOURNAL Submitted (05-DEC-2004) Cardiovascular/Metabolism, Schering-Plough
Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033,
USA
FEATURES Location/Qualifiers
source 1..1578
/db_xref="H-InvDB:HIT000332459"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="12"
/map="12q24"
/cell_line="THP-1"
gene 1..1578
/gene="P2RX7"
CDS 658..1578
/gene="P2RX7"
/note="P2X purinoceptor 7; ligand-gated ion channel; ATP
receptor; alternatively spliced"
/codon_start=1
/product="P2X7 isoform F"
/protein_id="AAX82091.1"
/translation="MWQFRYAKYYKENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQL
VVYIGSTLSYFGLAAVFIDFLIDTYSSNCCRSHIYPWCKCCQPCVVNEYYYRKKCESI
VEPKPTLKYVSFVDESHIRMVNQQLLGRSLQDVKGQEVPRPAMDFTDLSRLPLALHDT
PPIPGQPEEIQLLRKEATPRSRDSPVWCQCGSCLPSQLPESHRCLEELCCRKKPGACI
TTSELFRKLVLSRHVLQFLLLYQEPLLALDVDSTNSRLRHCAYRCYATWRFGSQDMAD
FAILPSCCRWRIRKEFPKSEGQYSGFKSPY"
BASE COUNT 388 a 422 c 408 g 360 t
ORIGIN
1 atgccggcct gctgcagctg cagtgatgtt ttccagtatg agacgaacaa agtcactcgg
61 atccagagca tgaattatgg caccattaag tggttcttcc acgtgatcat cttttcctac
121 gtttgctttg ctctggtgag tgacaagctg taccagcgga aagagcctgt catcagttct
181 gtgcacacca aggtgaaggg gatagcagag gtgaaagagg agatcgtgga gaatggagtg
241 aagaagttgg tgcacagtgt ctttgacacc gcagactaca ccttcccttt gcaggggaac
301 tctttcttcg tgatgacaaa ctttctcaaa acagaaggcc aagagcagcg gttgtgtccc
361 gaggaattca gaccggaagg tgtgtagtgc atgaagggaa ccagaagacc tgtgaagtct
421 ctgcctggtg ccccatcgag gcagtggaag aggccccccg gcctgctctc ttgaacagtg
481 ccgaaaactt cactgtgctc atcaagaaca atatcgactt ccccggccac aactacacca
541 cgagaaacat cctgccaggt ttaaacatca cttgtacctt ccacaagact cagaatccac
601 agtgtcccat tttccgacta ggagacatct tccgagaaac aggcgataat ttttcagatg
661 tggcaattca gatacgccaa gtactacaag gaaaacaatg ttgagaaacg gactctgata
721 aaagtcttcg ggatccgttt tgacatcctg gtttttggca ccggaggaaa atttgacatt
781 atccagctgg ttgtgtacat cggctcaacc ctctcctact tcggtctggc cgctgtgttc
841 atcgacttcc tcatcgacac ttactccagt aactgctgtc gctcccatat ttatccctgg
901 tgcaagtgct gtcagccctg tgtggtcaac gaatactact acaggaagaa gtgcgagtcc
961 attgtggagc caaagccgac attaaagtat gtgtcctttg tggatgaatc ccacattagg
1021 atggtgaacc agcagctact agggagaagt ctgcaagatg tcaagggcca agaagtccca
1081 agacctgcga tggacttcac agatttgtcc aggctgcccc tggccctcca tgacacaccc
1141 ccgattcctg gacaaccaga ggagatacag ctgcttagaa aggaggcgac tcctagatcc
1201 agggatagcc ccgtctggtg ccagtgtgga agctgcctcc catctcaact ccctgagagc
1261 cacaggtgcc tggaggagct gtgctgccgg aaaaagccgg gggcctgcat caccacctca
1321 gagctgttca ggaagctggt cctgtccaga cacgtcctgc agttcctcct gctctaccag
1381 gagcccttgc tggcgctgga tgtggattcc accaacagcc ggctgcggca ctgtgcctac
1441 aggtgctacg ccacctggcg cttcggctcc caggacatgg ctgactttgc catcctgccc
1501 agctgctgcc gctggaggat ccggaaagag tttccgaaga gtgaagggca gtacagtggc
1561 ttcaagagtc cttactga
//