LOCUS AY842014 3293 bp mRNA linear HUM 02-MAY-2005
DEFINITION Homo sapiens winged helix domain-containing protein isoform A
(C10orf24) mRNA, complete cds, alternatively spliced.
ACCESSION AY842014
VERSION AY842014.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3293)
AUTHORS van Dijk,M., Mulders,J., Poutsma,A., Konst,A.A., Lachmeijer,A.M.,
Dekker,G.A., Blankenstein,M.A. and Oudejans,C.B.
TITLE Maternal segregation of the Dutch preeclampsia locus at 10q22 with
a new member of the winged helix gene family
JOURNAL Nat. Genet. 37 (5), 514-519 (2005)
PUBMED 15806103
REFERENCE 2 (bases 1 to 3293)
AUTHORS Oudejans,C.B.M., van Dijk,M. and Mulders,J.
TITLE Direct Submission
JOURNAL Submitted (27-NOV-2004) Department of Clinical Chemistry, VU
University Medical Center, De Boelelaan 1117, Amsterdam, NH 1081
HV, The Netherlands
FEATURES Location/Qualifiers
source 1..3293
/db_xref="H-InvDB:HIT000257882"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="10"
/map="10q22.1"
/tissue_type="placenta"
/dev_stage="first trimester"
gene 1..3293
/gene="C10orf24"
CDS 1..2970
/gene="C10orf24"
/note="largest isoform; contains winged helix domain and
nuclear import and export sequences; expression includes
invasive extravillus trophoblast; alternatively spliced"
/codon_start=1
/product="winged helix domain-containing protein isoform
A"
/protein_id="AAW48524.1"
/translation="MARPVQLAPGSLALVLCRLEAQKAAGAAEEPGGRAVFRAFRRAN
ARCFWNARLARAASRLAFQGWLRRGVLLVRAPPACLQVLRDAWRRRALRPPRGFRIRA
VGDVFPVQMNPITQSQFVPLGEVLCCAISDMNTAQIVVTQESLLERLMKHYPGIAIPS
EDILYTTLGTLIKERKIYHTGEGYFIVTPQTYFITNTTTQENKRMLPSDESRLMPASM
TYLVSMESCAESAQENAAPISHCQSCQCFRDMHTQDVQEAPVAAEVTRKSHRGLGESV
SWVQNGAVSVSAEHHICESTKPLPYTRDKEKGKKFGFSLLWRSLSRKEKPKTEHSSFS
AQFPPEEWPVRDEDDLDNIPRDVEHEIIKRINPILTVDNLIKHTVLMQKYEEQKKYNS
QGTSTDMLTIGHKYPSKEGVKKRQGLSAKPQGQGHSRRDRHKARNQGSEFQPGSIRLE
KHPKLPATQPIPRIKSPNEMVGQKPLGEITTVLGSHLIYKKRISNPFQGLSHRGSTIS
KGHKIQKTSDLKPSQTGPKEKPFQKPRSLDSSRIFDGKAKEPYAEQPNDKMEAESIYI
NDPTVKPINDDFRGHLFSHPQQSMLQNDGKCCPFMESMLRYEVYGGENEVIPEVLRKS
HSHFDKLGETKQTPHSLPSRGASFSDRTPSACRLVDNTIHQFQNLGLLDYPVGVNPLR
QAARQDKDSEELLRKGFVQDAETTSLENEQLSNDDQALYQNEVEDDDGACSSLYLEED
DISENDDLRQMLPGHSQYSFTGGSQGNHLGKQKVIERSLTEYNSTMERVESQVLKRNE
CYKPTGLHATPGESQEPNLSAESCGLNSGAQFGFNYEEEPSVAKCVQASAPADERIFD
YYSARKASFEAEVIQDTIGDTGKKPASWSQSPQNQEMRKHFPQKFQLFNTSHMPVLAQ
DVQYEHSHLEGTENHSMAGDSGIDSPRTQSLGSNNSVILDGLKRRQNFLQNVEGTKSS
QPLTSNSLLPLTPVINV"
misc_feature 370..630
/gene="C10orf24"
/note="Region: winged helix domain"
BASE COUNT 994 a 726 c 770 g 803 t
ORIGIN
1 atggcccggc ccgtgcagct ggcgccgggc tcgctggcgc tagtgctgtg ccggctggag
61 gcgcagaagg cggcgggggc cgcggaggag cctggtgggc gcgcggtgtt ccgcgctttc
121 cgtcgcgcca acgcgcgctg cttctggaac gcgcggctgg cgcgcgccgc ctcgcggctg
181 gccttccagg gctggctgcg gcggggggtg ctgctggtgc gcgcgccccc cgcctgcctg
241 caggtgctgc gcgatgcctg gcggcgccgg gccctgcggc cgccgcgcgg cttccgcatc
301 agggcggtgg gtgatgtctt tccagtgcaa atgaatccaa taactcaatc tcagttcgta
361 cctttgggtg aagttctttg ctgtgctata tctgatatga atacagctca gattgtagta
421 acgcaggaat cacttttgga gcgtttgatg aaacattacc caggcattgc aattccatcg
481 gaagatattc tttataccac tctgggaacg ctgattaaag aaaggaagat ttatcacact
541 ggagaaggat acttcatagt tactcctcag acttacttca ttacaaatac aaccacccag
601 gaaaataaga gaatgctgcc atcagatgaa agtcgcctga tgccagcttc catgacatat
661 ctggtgagca tggagagctg tgcagagtca gcccaagaga atgctgcccc catatcccac
721 tgtcagtctt gccagtgttt ccgggacatg cacactcagg atgttcagga agcaccagtt
781 gctgcagaag tgactaggaa gagtcacaga ggtcttgggg aatccgtatc ttgggtacag
841 aatggggcag tttcagtgtc tgcggagcac cacatttgtg agagcaccaa acctttacca
901 tacacaagag ataaagaaaa aggcaagaag tttggtttta gtctcttatg gcgcagctta
961 tctagaaagg agaagcccaa aacagaacac agcagtttct ctgctcagtt cccacctgaa
1021 gaatggcccg tccgagatga agatgacttg gacaatatcc ctcgagatgt tgaacatgag
1081 ataatcaaac gaattaaccc cattttgact gttgacaatt taatcaaaca cactgtccta
1141 atgcaaaaat acgaagaaca gaaaaaatat aatagccagg gcacttccac tgacatgctg
1201 acaatcgggc ataagtatcc ttcaaaagag ggggttaaga aaaggcaggg tctgtctgca
1261 aaacctcaag ggcagggcca ttctcgaagg gatagacaca aagccaggaa tcagggaagt
1321 gagtttcagc caggaagcat tagactggag aaacacccca agctccctgc tacacagccc
1381 atccccagaa ttaaaagccc aaatgaaatg gtaggtcaga aaccacttgg tgagattaca
1441 acagtgctag gttcccattt gatttacaaa aagcgaatca gtaatccttt ccagggtttg
1501 tctcaccgag gaagcacaat atccaaaggg cacaaaattc agaagacgag tgatctgaaa
1561 cccagccaga ctggaccaaa ggaaaagcct ttccaaaagc ctaggtcctt ggattcctca
1621 agaatctttg atggtaaagc caaagagcca tatgctgaac aacctaatga taaaatggaa
1681 gcagaatcca tttacataaa tgaccctact gtcaaaccca tcaatgatga cttcagaggt
1741 cacctcttca gtcaccctca acagagcatg ttgcaaaatg atggtaaatg ctgtcccttt
1801 atggaaagca tgttgagata tgaagtgtat ggtggagaaa atgaggtaat tcctgaagtc
1861 ttgaggaaaa gtcattccca ctttgacaaa ttaggggaga ccaaacagac tccgcatagt
1921 ctgccatcac gaggtgcctc cttttcagac cgaacaccct ctgcttgtag attagtggat
1981 aacacaatac accagtttca aaatcttggc cttttggatt acccagttgg cgtgaaccct
2041 ttaagacaag ctgcaagaca agacaaagac tcagaagaat tattgagaaa aggatttgtc
2101 caggatgcag agactacaag cctagaaaat gaacagcttt ctaacgatga ccaggccttg
2161 tatcagaatg aagtggaaga tgatgatggt gcctgtagtt cattatatct agaggaggat
2221 gacatttctg agaatgacga cttacgtcaa atgctgcctg gccacagtca gtattccttc
2281 acaggtggaa gccagggaaa tcatttagga aaacaaaaag tgattgagag atctctgacc
2341 gagtacaaca gcacaatgga gagggttgag tctcaggtgc ttaaaagaaa tgaatgctac
2401 aaacccactg ggctgcatgc taccccaggt gaaagccaag aacctaacct ctctgctgaa
2461 agttgtggcc taaattcagg ggcccagttt ggttttaact acgaagaaga acccagtgtt
2521 gctaaatgtg tacaggcctc agcacctgct gatgaaagaa tctttgatta ctatagcgca
2581 agaaaagcca gttttgaagc tgaagtcata caagacacta ttggtgacac aggaaagaag
2641 ccagctagct ggagtcagag tcctcagaat caggaaatga gaaaacattt cccacaaaag
2701 ttccaacttt tcaacacttc acatatgcca gtgttggctc aggatgtcca atatgaacac
2761 agtcacttgg aagggacaga aaatcacagc atggcaggag atagtggaat agattctcca
2821 cggacacaga gtctgggatc taataattca gtcattttgg atggactaaa aagaagacag
2881 aattttctgc aaaatgtcga aggcacaaag agcagtcaac cactcacatc taattcctta
2941 ctaccgctaa ctccagtcat aaacgtttaa ttttcttttg gaaacctact tttttcttta
3001 taaaaaggta gagcattatt acagaatctt tcaatcatgt aagaattgag tatataagaa
3061 ttgtctaaag gcaagcatat ctatactatt aaccacatta cacattttgt tctaattact
3121 ggcttttttt cctcttttgg tgtcttaagg ctttttgaag cttattttac tgtgagttta
3181 ttgggagtat atagattatt ttcgattaaa aagtggaatt attggtcccc ttccaattgt
3241 aattatcttg aatttttata cattagtttc tcaaatatat agaatgccaa ttt
//