LOCUS AY827075 2784 bp mRNA linear HUM 16-JAN-2007
DEFINITION Homo sapiens F-box protein 11 (FBXO11) mRNA, complete cds.
ACCESSION AY827075
VERSION AY827075.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2784)
AUTHORS Abida,W.M., Nikolaev,A., Zhao,W., Zhang,W. and Gu,W.
TITLE FBXO11 promotes the Neddylation of p53 and inhibits its
transcriptional activity
JOURNAL J. Biol. Chem. 282 (3), 1797-1804 (2007)
PUBMED 17098746
REFERENCE 2 (bases 1 to 2784)
AUTHORS Nikolaev,A. and Gu,W.
TITLE Direct Submission
JOURNAL Submitted (15-NOV-2004) Pathology, Columbia University, 1150 St.
Nicholas Ave., New York, NY 10032, USA
FEATURES Location/Qualifiers
source 1..2784
/db_xref="H-InvDB:HIT000332393"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2784
/gene="FBXO11"
CDS 1..2784
/gene="FBXO11"
/note="p53-specific E3 ligase"
/codon_start=1
/product="F-box protein 11"
/protein_id="AAV87312.1"
/translation="MNSVRAANRRPRRVSRPRPVQQQQQQPPQQPPPQPPQQQPPQQQ
PPPPPQQQQQQQPPPPPPPPPPLPQERNNVGERDDDVPADMVAEESGPGAQNSPYQLR
RKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQDLSAAPAEQYLQEKLP
DEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPEPGKF
YQINPEEYEHPNPWKESFQQLYKGAHVKPGFAEHFYSNPARYKGRENMLYYDTIEDAL
GGVQEAHFDGLIFVHSGIYTDEWIYIESPITMIGAAPGKVADKVIIENTRDSTFVFME
GSEDAYVGYMTIRFNPDDKSAQHHNAHHCLEITVNCSPIIDHCIIRSTCTVGSAVCVS
GQGACPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNH
IHHGRDVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGGIYVH
EKGRGQFIENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDI
YGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTT
GSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIW
GGQNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDSNPTLRRNKIHDGRDGGICIFNG
GRGLLEENDIFRNAQAGVLISTNSHPILRKNRIFDGFAAGIEITNHATATLEGNQIFN
NRFGGLFLASGVNVTMKDNKIMNNQDAIEKAVSRGQCLYKISSYTSYPMHDFYRCHTC
NTTDRNAICVNCIKKCHQGHDVEFIRHDRFFCDCGAGTLSNPCTLASEPTHDTDTLYD
SAPPIESNTLQHN"
BASE COUNT 905 a 533 c 636 g 710 t
ORIGIN
1 atgaactccg tccgagccgc caaccggaga cccaggcgag tgtcgcggcc gcgcccggtg
61 cagcaacagc agcagcagcc cccgcagcag ccgccgccgc agccgcccca gcagcagccg
121 ccccagcagc agcctccgcc gccgccgcag cagcagcagc agcagcagcc tccgccgccg
181 ccaccgccgc ctccgccgct gcctcaggag cggaacaacg tcggcgagcg ggatgatgat
241 gtgcctgcag atatggttgc agaagaatca ggtcctggtg cacaaaatag tccataccaa
301 cttcgtagaa aaactctttt gccgaaaaga acagcgtgtc ccacaaagaa cagtatggag
361 ggcgcctcaa cttcaactac agaaaacttt ggtcatcgtg caaaacgtgc aagagtgtct
421 ggaaaatcac aagatctatc agcagcacct gctgaacagt atcttcagga gaaactgcca
481 gatgaagtgg ttctaaaaat cttctcttac ttgctggaac aggatctttg tagagcagct
541 tgtgtatgta aacgcttcag tgaacttgct aatgatccaa ttttgtggaa acgattatat
601 atggaagtat ttgaatatac tcgccctatg atgcatcctg aacctggaaa attctaccag
661 attaatccag aagagtatga acatccaaat ccctggaaag agagtttcca gcagttgtat
721 aaaggtgcac atgtaaagcc aggatttgct gaacatttct acagtaaccc tgcaagatat
781 aaaggaagag aaaatatgtt gtattatgat actattgaag atgcccttgg tggggtacaa
841 gaggctcatt ttgatggact tatctttgtt cattctggaa tatatactga tgaatggata
901 tatattgaat ctccaatcac catgattggt gcagcacctg ggaaagtggc agacaaagtt
961 ataattgaaa acactagaga ttcaaccttc gtttttatgg aaggctctga agatgcttat
1021 gttggatata tgacaataag gtttaaccct gatgacaaat ctgcacaaca ccacaatgca
1081 caccactgct tagagattac agtaaattgt agccctatta ttgatcactg tatcatccga
1141 agtacatgta cagttggttc tgcagtatgt gttagtggtc aaggagcatg tcccaccatc
1201 aagcactgta acatcagtga ctgtgaaaat gttggactat atataacaga tcatgcacag
1261 ggaatatatg aggataatga aatttccaat aatgcgttag ctgggatttg ggttaaaaat
1321 catggaaacc caattattag acggaatcat attcatcatg gacgtgatgt tggtgtgttc
1381 acatttgatc atggcatggg ttactttgaa agttgcaata tacacagaaa taggatagca
1441 ggctttgaag taaaagccta tgctaaccct acagtggttc gatgtgaaat tcaccatggg
1501 cagactggag gaatatatgt ccatgaaaaa ggaagaggac aattcataga gaataaaatc
1561 tatgcaaaca actttgcagg tgtatggatt acctcaaata gtgacccaac aataagggga
1621 aattctatat ttaatggaaa tcaaggagga gtttacatct ttggtgatgg acgaggcctt
1681 attgaaggaa atgacattta tggcaatgca ttagcaggaa ttcaaattag gacaaacagt
1741 tgtccaattg ttcggcataa caaaattcat gatggccagc atggtgggat ttatgtgcat
1801 gaaaagggac aaggagtaat agaagagaat gaagtttata gtaacactct agctggagtc
1861 tgggtgacaa ctggcagcac tccagtactg agaagaaacc ggatacacag tggcaagcag
1921 gttggtgttt atttttatga caatggacat ggagtgctag aagacaatga tatctataat
1981 catatgtatt caggggttca gataaggact ggaagcaacc ccaaaattag acgcaacaaa
2041 atctggggag gacagaatgg tggaattcta gtttataatt ctggtctagg ctgtatagaa
2101 gacaatgaaa tatttgacaa tgcaatggct ggagtctgga ttaagacaga tagtaatcct
2161 acactaagaa gaaataaaat ccatgatgga agagatggtg gcatctgtat atttaatggg
2221 ggtcgaggtc tccttgaaga aaatgatatt ttcaggaatg ctcaagcagg tgttctcatc
2281 agcactaata gtcatccaat cttaaggaaa aacagaatat ttgatggatt tgccgcaggt
2341 attgaaatta caaatcacgc aactgcaaca ctagaaggca atcagatttt taacaaccgg
2401 tttggaggct tatttttagc atctggtgtt aatgtgacaa tgaaagataa caaaataatg
2461 aacaatcaag atgccataga aaaggctgtt agtagaggcc aatgtttata taaaatatca
2521 agttatacca gctatcccat gcatgatttc tacagatgtc atacttgtaa caccacagat
2581 cgaaatgcca tatgtgtgaa ctgcattaag aagtgccatc agggacatga tgtagagttt
2641 attagacatg ataggttttt ctgtgactgt ggtgctggaa cactgtctaa tccttgtaca
2701 ttagctagtg agcctacaca tgatacagat acactatatg actctgctcc acctatagaa
2761 tctaatacat tgcagcacaa ctga
//