LOCUS AY775058 3939 bp mRNA linear HUM 20-DEC-2004
DEFINITION Homo sapiens misshapen/NIKs-related kinase isoform beta (MINK)
mRNA, complete cds, alternatively spliced.
ACCESSION AY775058
VERSION AY775058.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3939)
AUTHORS Hu,Y., Leo,C., Yu,S., Huang,B.C., Wang,H., Shen,M., Luo,Y.,
Daniel-Issakani,S., Payan,D.G. and Xu,X.
TITLE Identification and functional characterization of a novel human
misshapen/Nck interacting kinase-related kinase, hMINK beta
JOURNAL J. Biol. Chem. 279 (52), 54387-54397 (2004)
PUBMED 15469942
REMARK Erratum:[J Biol Chem. 2005 Feb 11;280(6):5128]
REFERENCE 2 (bases 1 to 3939)
AUTHORS Hu,Y., Leo,C., Yu,S., Huang,B.C.B., Wang,H., Shen,M., Luo,Y.,
Daniel-Issakani,S., Payan,D.G. and Xu,X.
TITLE Direct Submission
JOURNAL Submitted (08-OCT-2004) HTS, Rigel Pharmaceuticals, Inc, 1080
Veterans Blvd., San Francisco, CA 94306, USA
FEATURES Location/Qualifiers
source 1..3939
/db_xref="H-InvDB:HIT000257674"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..3939
/gene="MINK"
/note="hMINK"
CDS 1..3939
/gene="MINK"
/note="hMINKbeta; alternatively spliced"
/codon_start=1
/product="misshapen/NIKs-related kinase isoform beta"
/protein_id="AAV41830.1"
/translation="MGDPAPARSLDDIDLSALRDPAGIFELVEVVGNGTYGQVYKGRH
VKTGQLAAIKVMDVTEDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGNDDQLW
LVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKGQNVL
LTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDIWS
LGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFIDFIDTCLIKTYLS
RPPTEQLLKFPFIRDQPTERQVRIQLKDHIDRSRKKRGEKEETEYEYSGSEEEDDSHG
EEGEPSSIMNVPGESTLRREFLRLQQENKSNSEALKQQQQLQQQQQRDPEAHIKHLLH
QRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLEDMQALRREEERRQAEREQE
YKRKQLEEQRQSERLQRQLQQEHAYLKSLQQQQQQQQLQKQQQQQLLPGDRKPLYHYG
RGMNPADKPAWAREVEERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPGPLSQTP
PMQRPVEPQEGPHKSLQDQPTRNLAAFPASHDPDPAIPAPTATPSARGAVIRQNSDPT
SEGPGPSPNPPAWVRPDNEAPPKVPQRTSSIATALNTSGAGGSRPAQAVRARPRSNSA
WQIYLQRRAERGTPKPPGPPAQPPGPPNASSNPDLRRSDPGWERSDSVLPASHGHLPQ
AGSLERNRVGASSKLDSSPVLSPGNKAKPDDHRSRPGRPADFVLLKERTLDEAPRPPK
KAMDYSSSSEEVESSEDDEEEGEGGPAEGSRDTPGGRSDGDTDSVSTMVVHDVEEITG
TQPPYGGGTMVVQRTPEEERNLLHADSNGYTNLPDVVQPSHSPTENSKGQSPPSKDGS
GDYQSRGLVKAPGKSSFTMFVDLGIYQPGGSGDSIPITALVGGEGTRLDQLQYDVRKG
SVVNVNPTNTRAHSETPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGK
VYGLIGRRRFQQMDVLEGLNLLITISGKRNKLRVYYLSWLRNKILHNDPEVEKKQGWT
TVGDMEGCGHYRVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFADLPHRPLL
VDLTVEEGQRLKVIYGSSAGFHAVDVDSGNSYDIYIPVHIQSQITPHAIIFLPNTDGM
EMLLCYEDEGVYVNTYGRIIKDVVLQWGEMPTSVAYICSNQIMGWGEKAIEIRSVETG
HLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLNRNCIMNW"
BASE COUNT 926 a 1192 c 1195 g 626 t
ORIGIN
1 atgggcgacc cagcccccgc ccgcagcctg gacgacatcg acctgtccgc cctgcgggac
61 cctgctggga tctttgagct tgtggaggtg gtcggcaatg gaacctacgg acaggtgtac
121 aagggtcggc atgtcaagac ggggcagctg gctgccatca aggtcatgga tgtcacggag
181 gacgaggagg aagagatcaa acaggagatc aacatgctga aaaagtactc tcaccaccgc
241 aacatcgcca cctactacgg agccttcatc aagaagagcc ccccgggaaa cgatgaccag
301 ctctggctgg tgatggagtt ctgtggtgct ggttcagtga ctgacctggt aaagaacaca
361 aaaggcaacg ccctgaagga ggactgtatc gcctatatct gcagggagat cctcaggggt
421 ctggcccatc tccatgccca caaggtgatc catcgagaca tcaaggggca gaatgtgctg
481 ctgacagaga atgctgaggt caagctagtg gattttgggg tgagtgctca gctggaccgc
541 accgtgggca gacggaacac tttcattggg actccctact ggatggctcc agaggtcatc
601 gcctgtgatg agaaccctga tgccacctat gattacagga gtgatatttg gtctctagga
661 atcacagcca tcgagatggc agagggagcc ccccctctgt gtgacatgca ccccatgcga
721 gccctcttcc tcattcctcg gaaccctccg cccaggctca agtccaagaa gtggtctaag
781 aagttcattg acttcattga cacatgtctc atcaagactt acctgagccg cccacccacg
841 gagcagctac tgaagtttcc cttcatccgg gaccagccca cggagcggca ggtccgcatc
901 cagcttaagg accacattga ccgatcccgg aagaagcggg gtgagaaaga ggagacagaa
961 tatgagtaca gcggcagcga ggaggaagat gacagccatg gagaggaagg agagccaagc
1021 tccatcatga acgtgcctgg agagtcgact ctacgccggg agtttctccg gctccagcag
1081 gaaaataaga gcaactcaga ggctttaaaa cagcagcagc agctgcagca gcagcagcag
1141 cgagaccccg aggcacacat caaacacctg ctgcaccagc ggcagcggcg catagaggag
1201 cagaaggagg agcggcgccg cgtggaggag caacagcggc gggagcggga gcagcggaag
1261 ctgcaggaga aggagcagca gcggcggctg gaggacatgc aggctctgcg gcgggaggag
1321 gagcggcggc aggcggagcg tgagcaggaa tacaagcgga agcagctgga ggagcagcgg
1381 cagtcagaac gtctccagag gcagctgcag caggagcatg cctacctcaa gtccctgcag
1441 cagcagcaac agcagcagca gcttcagaaa cagcagcagc agcagctcct gcctggggac
1501 aggaagcccc tgtaccatta tggtcggggc atgaatcccg ctgacaaacc agcctgggcc
1561 cgagaggtag aagagagaac aaggatgaac aagcagcaga actctccctt ggccaagagc
1621 aagccaggca gcacggggcc tgagcccccc atcccccagg cctccccagg gcccccagga
1681 cccctttccc agactcctcc tatgcagagg ccggtggagc cccaggaggg accgcacaag
1741 tccctgcagg accagcccac ccgaaacctg gctgccttcc cagcctccca tgaccccgac
1801 cctgccatcc ccgcacccac tgccacgccc agtgcccgag gagctgtcat ccgccagaat
1861 tcagacccca cctctgaagg acctggcccc agcccgaatc ccccagcctg ggtccgccca
1921 gataacgagg ccccacccaa ggtgcctcag aggacctcat ctatcgccac tgcccttaac
1981 accagtgggg ccggagggtc ccggccagcc caggcagtcc gtgccagacc tcgcagcaac
2041 tccgcctggc aaatctatct gcaaaggcgg gcagagcggg gcaccccaaa gcctccaggg
2101 ccccctgctc agccccctgg cccgcccaac gcctctagta accccgacct caggaggagc
2161 gaccctggct gggaacgctc ggacagcgtc cttccagcct ctcacgggca cctcccccag
2221 gctggctcac tggagcggaa ccgcgtggga gcctcctcca aactggacag ctcccctgtg
2281 ctctcccctg ggaataaagc caagcccgac gaccaccgct cacggccagg ccggcccgca
2341 gactttgtgt tgctgaaaga gcggactctg gacgaggccc ctcggcctcc caagaaggcc
2401 atggactact cgtcgtccag cgaggaggtg gaaagcagtg aggacgacga ggaggaaggc
2461 gaaggcgggc cagcagaggg gagcagagat acccctgggg gccgcagcga tggggataca
2521 gacagcgtca gcaccatggt ggtccacgac gtcgaggaga tcaccgggac ccagccccca
2581 tacgggggcg gcaccatggt ggtccagcgc acccctgaag aggagcggaa cctgctgcat
2641 gctgacagca atgggtacac aaacctgcct gacgtggtcc agcccagcca ctcacccacc
2701 gagaacagca aaggccaaag cccaccctcg aaggatggga gtggtgacta ccagtctcgt
2761 gggctggtaa aggcccctgg caagagctcg ttcacgatgt ttgtggatct agggatctac
2821 cagcctggag gcagtgggga cagcatcccc atcacagccc tagtgggtgg agagggcact
2881 cggctcgacc agctgcagta cgacgtgagg aagggttctg tggtcaacgt gaatcccacc
2941 aacacccggg cccacagtga gacccctgag atccggaagt acaagaagcg attcaactcc
3001 gagatcctct gtgcagccct ttggggggtc aacctgctgg tgggcacgga gaacgggctg
3061 atgttgctgg accgaagtgg gcagggcaag gtgtatggac tcattgggcg gcgacgcttc
3121 cagcagatgg atgtgctgga ggggctcaac ctgctcatca ccatctcagg gaaaaggaac
3181 aaactgcggg tgtattacct gtcctggctc cggaacaaga ttctgcacaa tgacccagaa
3241 gtggagaaga agcagggctg gaccaccgtg ggggacatgg agggctgcgg gcactaccgt
3301 gttgtgaaat acgagcggat taagttcctg gtcatcgccc tcaagagctc cgtggaggtg
3361 tatgcctggg cccccaaacc ctaccacaaa ttcatggcct tcaagtcctt tgccgacctc
3421 ccccaccgcc ctctgctggt cgacctgaca gtagaggagg ggcagcggct caaggtcatc
3481 tatggctcca gtgctggctt ccatgctgtg gatgtcgact cggggaacag ctatgacatc
3541 tacatccctg tgcacatcca gagccagatc acgccccatg ccatcatctt cctccccaac
3601 accgacggca tggagatgct gctgtgctac gaggacgagg gtgtctacgt caacacgtac
3661 gggcgcatca ttaaggatgt ggtgctgcag tggggggaga tgcctacttc tgtggcctac
3721 atctgctcca accagataat gggctggggt gagaaagcca ttgagatccg ctctgtggag
3781 acgggccacc tcgacggggt cttcatgcac aaacgagctc agaggctcaa gttcctgtgt
3841 gagcggaatg acaaggtgtt ttttgcctca gtccgctctg ggggcagcag ccaagtttac
3901 ttcatgactc tgaaccgtaa ctgcatcatg aactggtga
//