LOCUS AY645722 1358 bp mRNA linear HUM 30-MAR-2005
DEFINITION Homo sapiens MHC class II antigen (HLA-DMB) mRNA, complete cds.
ACCESSION AY645722
VERSION AY645722.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1358)
AUTHORS Gu,H., Moon,S.M., Kim,J.J., Ryu,H.J., Kwack,K., Kimm,K., Lee,J.K.
and Oh,B.
TITLE Identification of a novel HLA-DMB allele (DMB*0107) in the Korean
population
JOURNAL Tissue Antigens 65 (4), 393-394 (2005)
PUBMED 15787724
REFERENCE 2 (bases 1 to 1358)
AUTHORS Lee,J.-K. and Gu,H.
TITLE Direct Submission
JOURNAL Submitted (04-JUN-2004) National Genome Research Institute, 5
Nokbeon-dong, Eunpyeng-gu, Seoul 122-701, Republic of Korea
FEATURES Location/Qualifiers
source 1..1358
/db_xref="H-InvDB:HIT000332058_04"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..1358
/gene="HLA-DMB"
CDS 234..1025
/gene="HLA-DMB"
/codon_start=1
/product="MHC class II antigen"
/protein_id="AAV97947.1"
/translation="MITFLPLLLGLSLGCTGAGGFVAHVESACLLDDAGTPKDFTYCI
SFNKVLLTCWDPEENKMAPCEFGVLNNLANVLSQHLNQKDTLMQRLRNGLQNCATHTQ
PFWGSLTNRTRPPSVQVAKTTPFNTREPVMLACYVWGFYPAEVTITWRKNGKLVMPHS
SAHKTAQPNGDWTYQTLSHLALTPSYGDTYTCVVEHIGAPEPILRDWTPGLSPMQTLK
VSVSAVTLGLGLIIFSLGVISWRRAGHSSYTPLPGSNYSEGWHIS"
variation 315
/gene="HLA-DMB"
/note="results in alanine to threonine substitution"
/replace="a"
variation 379
/gene="HLA-DMB"
/note="results in valine to aspartic acid substitution"
/replace="a"
variation 445
/gene="HLA-DMB"
/note="results in asparagine to serine substitution"
/replace="g"
BASE COUNT 318 a 367 c 347 g 326 t
ORIGIN
1 cctgtttggg acactggact cccgtgagct ggaaggaaca gatttaatat ctaggggctg
61 ggtatcccca catcactcat ttggggggtc aagggacccg ggcaatatag tattctgctc
121 agtgtctgga gatcatctac ccaggctggg gcttctggga caggcgagga cccacggacc
181 ctggaagagc tggtccaggg gactgaactc ccggcatctt tacagagcag agcatgatca
241 cattcctgcc gctgctgctg gggctcagcc tgggctgcac aggagcaggt ggcttcgtgg
301 cccatgtgga aagcgcctgt ctgttggatg atgctgggac tccaaaggat ttcacatact
361 gcatctcctt caacaaggtt ctgctgacct gctgggatcc agaggagaat aagatggccc
421 cttgcgaatt tggggtgctg aataacttgg cgaatgtcct ctcacagcac ctcaaccaaa
481 aagacaccct gatgcagcgc ttgcgcaatg ggcttcagaa ttgtgccaca cacacccagc
541 ccttctgggg atcactgacc aacaggacac ggccaccatc tgtgcaagta gccaaaacca
601 ctccttttaa cacgagggag cctgtgatgc tggcctgcta tgtgtggggc ttctatccag
661 cagaagtgac tatcacgtgg aggaagaacg ggaagcttgt catgcctcac agcagtgcgc
721 acaagactgc ccagcccaat ggagactgga cataccagac cctctcccat ttagccttaa
781 ccccctctta cggggacact tacacctgtg tggtagagca cattggggct cctgagccca
841 tccttcggga ctggacacct gggctgtccc ccatgcagac cctgaaggtt tctgtgtctg
901 cagtgactct gggcctgggc ctcatcatct tctctcttgg tgtgatcagc tggcggagag
961 ctggccactc tagttacact cctcttcctg ggtccaatta ttcagaagga tggcacattt
1021 cctagaggca gaatcctaca acttccactc caagtgagaa ggagattcaa actcaatgat
1081 gctaccatgc ctctccaaca tcttcaaccc cctgacatta tcttggatcc tatggtttct
1141 ccatccaatt ctttgaattt cccagtctcc cctatgtaaa acttagcaac ttgggggacc
1201 tcattcctgg gactatgctg taaccaaatt attgtccaag gctatatttc tgggatgaat
1261 ataatctgag gaagggagtt aaagaccctc ctggggctct cagtgtgcca tagaggacag
1321 caactggtga ttgtttcaga gaaataaact ttggtgga
//