LOCUS AY633572 3192 bp mRNA linear HUM 27-OCT-2004
DEFINITION Homo sapiens transmembrane protease serine 3 isoform 5 (TMPRSS3)
mRNA, complete cds.
ACCESSION AY633572
VERSION AY633572.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3192)
AUTHORS Ahmed,Z.M., Li,X.C., Powell,S.D., Riazuddin,S., Young,T.L.,
Ramzan,K., Ahmad,Z., Luscombe,S., Dhillon,K., MacLaren,L.,
Ploplis,B., Shotland,L.I., Ives,E., Riazuddin,S., Friedman,T.B.,
Morell,R.J. and Wilcox,E.R.
TITLE Characterization of a new full length TMPRSS3 isoform and
identification of mutant alleles responsible for nonsyndromic
recessive deafness in Newfoundland and Pakistan
JOURNAL BMC Med. Genet. 5, 24 (2004)
PUBMED 15447792
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 3192)
AUTHORS Ahmed,Z.M., Wilcox,E.R. and Friedman,T.B.
TITLE Direct Submission
JOURNAL Submitted (23-MAY-2004) Laboratory of Molecular Genetics,
NIDCD/NIH, 5 Research Court, Rockville, MD 20850, USA
FEATURES Location/Qualifiers
source 1..3192
/db_xref="H-InvDB:HIT000255789"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="retina"
gene 1..3192
/gene="TMPRSS3"
/note="transcript variant E"
CDS 705..2321
/gene="TMPRSS3"
/note="serine protease TADG12"
/codon_start=1
/product="transmembrane protease serine 3 isoform 5"
/protein_id="AAT66641.1"
/translation="MQAVGPKPLPTLLCGGRTGHRTARVLSFLIRSCPCEPGKGCVYG
KPVTLWPTISSVVPSTFLGLGNYEVEVEAEPDVRGPEIVTMGENDPPAVEAPFSFRSL
FGLDDLKISPVAPDADAVAAQILSLLPLKFFPIIVIGIIALILALAIGLGIHFDCSGK
YRCRSSFKCIELIARCDGVSDCKDGEDEYRCVRVGGQNAVLQVFTAASWKTMCSDDWK
GHYANVACAQLGFPSYVSSDNLRVSSLEGQFREEFVSIDHLLPDDKVTALHHSVYVRE
GCASGHVVTLQCTACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPL
WIITAAHCVYDLYLPKSWTIQVGLVSLLDNPAPSHLVEKIVYHSKYKPKRLGNDIALM
KLAGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLIS
NKICNHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIG
CAEVNKPGVYTRVTSFLDWIHEQMERDLKT"
BASE COUNT 724 a 811 c 837 g 820 t
ORIGIN
1 ttctgctttt aatgatggca gctccagaaa tggtgagtaa aatgggtgtg aggagagaag
61 atgcttctca acacttctca gtgttgtaca gcttgccaac cacagcctgt ttgggagggg
121 atgttctcac ccaggttcca tctttcagaa gccatttgcc cacttattct ttttatatgg
181 ataaacgatg taatttgcta catgctgata ataaacagag gtatcagcaa gaatgaaagc
241 cagaaaatgg cccaacatga acttcttgct tttctaagtt actctttcaa gctcttcttg
301 cgatagaaat gaaatgaaca tttttggcac agaactcttg tttagatttt actatgatct
361 tgggaaacac gggttgcttc aaatggctta ctagatccct ttggaatttc aaacgttaca
421 acaggtagtc acaaagggaa tgaaagcgga tgatctgagt gtctgtgctg atgtgcctgc
481 tggagcccct gtggatttta gcccttggag gaagcaggtt cccagagcag ccatgcctga
541 tatctgggag agggaactag aatttaattg ggaatcttct gctatttccc tgcttcctcc
601 gccctctcag agttacaggg aatgacttag aaaggtctct ggtctccttg gcattgtgat
661 aggtggaatt ctttcgtagg aaacacagcc ccggggttat tttgatgcaa gccgttggtc
721 caaagccact ccccactttg ctatgtgggg gaaggaccgg gcaccggacg gctcgggtac
781 tttcgttctt aattaggtca tgcccgtgtg agccaggaaa gggctgtgtt tatgggaagc
841 cagtaacact gtggcctact atctcttccg tggtgccatc tacatttttg ggactcggga
901 attatgaggt agaggtggag gcggagccgg atgtcagagg tcctgaaata gtcaccatgg
961 gggaaaatga tccgcctgct gttgaagccc ccttctcatt ccgatcgctt tttggccttg
1021 atgatttgaa aataagtcct gttgcaccag atgcagatgc tgttgctgca cagatcctgt
1081 cactgctgcc attgaagttt tttccaatca tcgtcattgg gatcattgca ttgatattag
1141 cactggccat tggtctgggc atccacttcg actgctcagg gaagtacaga tgtcgctcat
1201 cctttaagtg tatcgagctg atagctcgat gtgacggagt ctcggattgc aaagacgggg
1261 aggacgagta ccgctgtgtc cgggtgggtg gtcagaatgc cgtgctccag gtgttcacag
1321 ctgcttcgtg gaagaccatg tgctccgatg actggaaggg tcactacgca aatgttgcct
1381 gtgcccaact gggtttccca agctatgtga gttcagataa cctcagagtg agctcgctgg
1441 aggggcagtt ccgggaggag tttgtgtcca tcgatcacct cttgccagat gacaaggtga
1501 ctgcattaca ccactcagta tatgtgaggg agggatgtgc ctctggccac gtggttacct
1561 tgcagtgcac agcctgtggt catagaaggg gctacagctc acgcatcgtg ggtggaaaca
1621 tgtccttgct ctcgcagtgg ccctggcagg ccagccttca gttccagggc taccacctgt
1681 gcgggggctc tgtcatcacg cccctgtgga tcatcactgc tgcacactgt gtttatgact
1741 tgtacctccc caagtcatgg accatccagg tgggtctagt ttccctgttg gacaatccag
1801 ccccatccca cttggtggag aagattgtct accacagcaa gtacaagcca aagaggctgg
1861 gcaatgacat cgcccttatg aagctggccg ggccactcac gttcaatgaa atgatccagc
1921 ctgtgtgcct gcccaactct gaagagaact tccccgatgg aaaagtgtgc tggacgtcag
1981 gatggggggc cacagaggat ggagcaggtg acgcctcccc tgtcctgaac cacgcggccg
2041 tccctttgat ttccaacaag atctgcaacc acagggacgt gtacggtggc atcatctccc
2101 cctccatgct ctgcgcgggc tacctgacgg gtggcgtgga cagctgccag ggggacagcg
2161 gggggcccct ggtgtgtcaa gagaggaggc tgtggaagtt agtgggagcg accagctttg
2221 gcatcggctg cgcagaggtg aacaagcctg gggtgtacac ccgtgtcacc tccttcctgg
2281 actggatcca cgagcagatg gagagagacc taaaaacctg aagaggaagg ggacaagtag
2341 ccacctgagt tcctgaggtg atgaagacag cccgatcctc ccctggactc ccgtgtagga
2401 acctgcacac gagcagacac ccttggagct ctgagttccg gcaccagtag caggcccgaa
2461 agaggcaccc ttccatctga ttccagcaca accttcaagc tgctttttgt tttttgtttt
2521 tttgaggtgg agtctcgctc tgttgcccag gctggagtgc agtggcgaaa tccctgctca
2581 ctgcagcctc cgcttccctg gttcaagcga ttctcttgcc tcagcttccc cagtagctgg
2641 gaccacaggt gcccgccacc acacccaact aatttttgta tttttagtag agacagggtt
2701 tcaccatgtt ggccaggctg ctctcaaacc cctgacctca aatgatgtgc ctgcttcagc
2761 ctcccacagt gctgggatta caggcatggg ccaccacgcc tagcctcacg ctcctttctg
2821 atcttcacta agaacaaaag aagcagcaac ttgcaagggc ggcctttccc actggtccat
2881 ctggttttct ctccaggggt cttgcaaaat tcctgacgag ataagcagtt atgtgacctc
2941 acgtgcaaag ccaccaacag ccactcagaa aagacgcacc agcccagaag tgcagaactg
3001 cagtcactgc acgttttcat ctctagggac cagaaccaaa cccacccttt ctacttccaa
3061 gacttatttt cacatgtggg gaggttaatc taggaatgac tcgtttaagg cctattttca
3121 tgatttcttt gtagcatttg gtgcttgacg tattattgtc ctttgattcc aaataatatg
3181 tttccttccc tc
//