LOCUS AY574902 3719 bp mRNA linear HUM 01-APR-2005
DEFINITION Homo sapiens regulated in COPD kinase transcript variant 2 mRNA,
complete cds.
ACCESSION AY574902
VERSION AY574902.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3719)
AUTHORS Watanabe,S., Kondo,S., Tanabe,E., Takao,E., Bacon,K.B. and
Encinas,J.A.
TITLE Molecular cloning and characterization of RCK, a MAPK kinase kinase
that specifically phosphorylates MKK4
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 3719)
AUTHORS Watanabe,S., Kondo,S., Tanabe,E., Takao,E., Bacon,K.B. and
Encinas,J.A.
TITLE Direct Submission
JOURNAL Submitted (17-MAR-2004) Research Center Kyoto, Bayer Yakuhin, Ltd.,
6-5-1-3 Kunimidai, Kizucho, Sorakugun, Kyoto 619-0216, Japan
FEATURES Location/Qualifiers
source 1..3719
/db_xref="H-InvDB:HIT000331954"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2q21.3"
CDS 32..3679
/note="MAPK kinase kinase; RCK"
/codon_start=1
/product="regulated in COPD kinase transcript variant 2"
/protein_id="AAT81411.1"
/translation="MSSMPKPERHAESLLDICHDTNSSPTDLMTVTKNQNIILQSISR
SEEFDQDGDCSHSTLVNEEEDPSGGRQDWQPRTEEFSTSHMKYSGRSIKFLLPPLSLL
PTRSGVLTIPQNHKFPKEKERNIPSLTSFVPKLSVSVRQSDELSPSNEPPGALVKSLM
DPTLRSSDGFIWSRNMCSFPKTNHHRQCLEKEENWKSKEIEECNKIEITHFEKGQSLV
SFENLKEGNIPAVREEDIDCHGSKTRKPEEENSQYLSSRKNESSVAKNYEQDPEIVCT
IPSKFQETQHSEITPSQDEEMRNNKAASKRVSLHKNEAMEPNNILEECTVLKSLSSVV
FDDPIDKLPEGCSSMETNIKISIAERAKPEMSRMVPLIHITFPVDGSPKEPVIAKPSL
QTRKGTIHNNHSVNIPVHQENDKHKMNSHRSKLDSKTKTSKKTPQNFVISTEGPIKPT
MHKTSIKTQIFPALGLVDPRPWQLPRFQKKMPQIAKKQSTHRTQKPKKQSFPCICKNP
GTQKSCVPLSVQPTEPRLNYLDLKYSDMFKEINSTANGPGIYEMFGTPVYCHVRETER
DENTYYREICSAPSGRRITNKCRSSHSERKSNIRTRLSQKKTHMKCPKTSFGIKQEHK
VLISKEKSSKAVHSNLHDIENGDGISEPDWQIKSSGNEFLSSKDEIHPMNLAQTPEQS
MKQNEFPPVSDLSIVEEVSMEESTGDRDISNNQILTTSLRDLQELEELHHQIPFIPSE
DSWAVPSEKNSNKYVQQEKQNTASLSKVNASRILTNDLEFDSVSDHSKTLTNFSFQAK
QESASSQTYQYWVHYLDHDSLANKSITYQMFGKTLSGTNSISQEIMDSVNNEELTDEL
LGCLAAELLALDEKDNNSCQKMANETDPENLNLVLRWRGSTPKEMGRETTKVKIQRHS
SGLRIYDREEKFLISNEKKIFSENSLKSEEPILWTKGEILGKGAYGTVYCGLTSQGQL
IAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVAYLGTCLQENTVSIFMEFV
PGGSISSIINRFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIK
LIDFGCARRLAWAGLNGTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFE
MATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFSENAADFVRMCLTRDQHERPSALQ
LLKHSFLERSH"
BASE COUNT 1271 a 769 c 763 g 916 t
ORIGIN
1 ttcaaagaaa cagcagcttt tggacatttt aatgagttct atgccaaaac cagaaagaca
61 tgctgagtca ttgcttgaca tttgtcatga tacaaactct tctccaactg atttgatgac
121 agttaccaaa aatcaaaaca tcatcttgca aagcatcagc agaagtgagg agttcgacca
181 agatggtgac tgcagtcatt ccacactggt taatgaagaa gaagatccca gtggtggtag
241 acaggactgg caacccagga cagaagagtt ttcgacctct catatgaagt acagtggccg
301 aagcatcaag ttccttctgc caccactgtc actcttgccc acgcgatctg gtgtccttac
361 tatcccccaa aatcacaagt ttccaaaaga aaaagaaaga aacattccaa gtctcacatc
421 ttttgtgcct aagctctcag tgtctgttcg tcaatctgat gagctcagcc catcaaacga
481 gcctccggga gccctagtta agtcgttgat ggatccgact ctcaggtctt ctgatggctt
541 catttggtca agaaacatgt gctcttttcc taagactaac catcacaggc aatgcctgga
601 gaaggaggaa aactggaaat ccaaggaaat agaagaatgt aacaaaattg aaatcactca
661 ctttgaaaaa gggcagtctt tggtgtcttt tgagaatttg aaggaaggca atattcctgc
721 agttagggaa gaggatattg actgccatgg tagtaaaacg cgaaaacctg aagaagagaa
781 ctctcaatat ctttcatcaa gaaagaatga gagttcagta gccaaaaact atgaacaaga
841 tccagaaata gtatgtacca ttccaagcaa gttccaagaa acccagcatt cagaaataac
901 tccaagccag gatgaagaga tgagaaataa taaagctgct tcaaaaagag tttcattaca
961 taaaaatgaa gcaatggaac caaacaatat tttagaagag tgtactgtac ttaaaagctt
1021 atccagtgta gtctttgatg accccattga taaactccca gaaggttgta gcagcatgga
1081 gacaaacata aaaatatcaa tagcagaaag agccaaacca gaaatgagta ggatggtgcc
1141 tcttatccac atcaccttcc ctgtggatgg aagccccaag gaaccagtga tagccaaacc
1201 aagcctccaa acaagaaagg gaaccattca taacaaccat agtgtcaaca tacctgtaca
1261 ccaagaaaat gacaagcata agatgaattc ccataggagt aagttggatt caaagaccaa
1321 gacaagtaag aagacacctc agaattttgt gatttctact gaaggtccca ttaagcctac
1381 catgcataaa accagcataa aaacacaaat tttcccggct ttgggacttg tggaccccag
1441 gccttggcaa ttgcccaggt ttcaaaagaa aatgccacag atagcaaaga agcaatcaac
1501 tcaccggact cagaaaccta aaaagcaatc atttccttgc atctgtaaaa atccaggaac
1561 acagaagtca tgtgttcctc tctctgttca accgacagag ccaagactaa attacctaga
1621 tcttaagtat agtgatatgt tcaaagaaat caattcaact gctaatggac ctggaatcta
1681 tgaaatgttt gggacccctg tttattgtca tgtgcgagag actgaaaggg atgaaaacac
1741 gtattaccgt gagatatgtt cggctccatc aggcagacgt atcaccaata aatgtcgatc
1801 ttcacacagt gagaggaaga gcaatatcag aacaagactt tctcagaaaa aaacacatat
1861 gaaatgccca aagacttcat ttggcattaa acaagagcac aaagtcttaa tttctaaaga
1921 aaagagttcc aaggctgtac atagcaacct acatgacatt gaaaatggtg atggtatttc
1981 agaaccagac tggcagataa agtcttcagg aaatgagttt ctatcttcca aagatgaaat
2041 tcatcccatg aacttggctc agacacctga gcagtccatg aaacagaatg aattccctcc
2101 tgtctcagat ttatccattg ttgaagaagt ttctatggaa gagtctactg gtgatagaga
2161 catttctaac aatcaaatac tcaccacaag cctcagagat ctgcaagaac ttgaagagct
2221 acatcaccag atcccattta tcccttcaga agacagctgg gcagtgccca gtgagaagaa
2281 ttctaacaag tatgtacagc aagaaaagca gaatacagca tctcttagta aagtaaatgc
2341 cagccgaatt ttaactaatg atctagagtt tgatagtgtt tcagatcact ctaaaacact
2401 tacaaatttc tctttccaag caaaacaaga aagtgcatct tcccagacat atcaatattg
2461 ggtacattat ttggatcatg atagtttagc aaataagtca atcacatatc aaatgtttgg
2521 aaaaacctta agtggcacaa attcaatttc ccaagaaatt atggactctg taaataatga
2581 agaattgaca gatgaactat taggttgtct agctgcagaa ttattagctc ttgatgagaa
2641 agataacaac tcttgccaaa aaatggcaaa tgaaacagat cctgaaaacc taaatcttgt
2701 cctcagatgg agaggaagta ccccaaaaga aatgggcaga gagacaacaa aagtcaaaat
2761 acagaggcat agtagtgggc tcaggatata tgacagggag gagaaatttc tcatctcaaa
2821 tgaaaagaag atattttctg aaaatagttt aaagtctgaa gaacctatcc tatggaccaa
2881 gggtgagatt cttggaaagg gagcctacgg cacagtatac tgtggtctca ctagtcaagg
2941 acagctaata gctgtaaaac aggtggcttt ggatacctct aataaattag ctgctgaaaa
3001 ggaataccgg aaactacagg aagaagtaga tttgctcaaa gcactgaaac atgtcaacat
3061 tgtggcctat ttggggacat gcttgcaaga gaacactgtg agcattttca tggagtttgt
3121 tcctggtggc tcaatctcta gtattataaa ccgttttggg ccattgcctg agatggtgtt
3181 ctgtaaatat acgaaacaaa tacttcaagg tgttgcttat ctccatgaga actgtgtggt
3241 acatcgcgat atcaaaggaa ataatgttat gctcatgcca actggaataa taaagctgat
3301 tgactttggc tgtgccaggc gtttggcctg ggcaggttta aatggcaccc acagtgacat
3361 gcttaagtcc atgcatggga ctccatattg gatggcccca gaagtcatca atgagtctgg
3421 ctatggacgg aaatcagata tctggagcat tggttgtact gtgtttgaga tggctacagg
3481 gaagcctcca ctggcttcca tggacaggat ggccgccatg ttttacatcg gagcacaccg
3541 agggctgatg cctcctttac cagaccactt ctcagaaaat gcagcagact ttgtgcgcat
3601 gtgcctgacc agggaccagc atgagcgacc ttctgctctc cagctcctga agcactcctt
3661 cttggagaga agtcactgaa tatacatcaa gactttcttc ccagttccac tgcagatgc
//