LOCUS AY512961 2452 bp mRNA linear HUM 13-FEB-2006
DEFINITION Homo sapiens truncated phospholipase C delta-4 (PLCD4) mRNA,
complete cds, alternatively spliced.
ACCESSION AY512961
VERSION AY512961.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2452)
AUTHORS Leung,D.W., Tompkins,C., Brewer,J., Ball,A., Coon,M., Morris,V.,
Waggoner,D. and Singer,J.W.
TITLE Phospholipase C delta-4 overexpression upregulates ErbB1/2
expression, Erk signaling pathway, and proliferation in MCF-7 cells
JOURNAL Mol. Cancer 3, 15 (2004)
PUBMED 15140260
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 2452)
AUTHORS Leung,D.W. and Tompkins,C.
TITLE Direct Submission
JOURNAL Submitted (23-DEC-2003) Molecular Biology, Cell Therapeutics, Inc.,
201 Elliott Ave., W., Suite 400, Seattle, WA 98040, USA
FEATURES Location/Qualifiers
source 1..2452
/db_xref="H-InvDB:HIT000255070"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2q35"
gene 1..2452
/gene="PLCD4"
CDS 250..1068
/gene="PLCD4"
/note="PLCd4b; alternatively spliced; exons 7, 8 and 9
missing resulting in premature termination"
/codon_start=1
/product="truncated phospholipase C delta-4"
/protein_id="AAS82574.1"
/translation="MASLLQDQLTTDQDLLLMQEGMPMRKVRSKSWKKLRYFRLQNDG
MTVWHARQARGSAKPSFSISDVETIRNGHDSELLRSLAEELPLEQGFTIVFHGRRSNL
DLMANSVEEAQIWMRGLQLLVDLVTSMDHQERLDQWLSDWFQRGDKNQDGKMSFQEVQ
RLLHLMNVEMDQEYAFSLFQAADTSQSGTLEGEEFVQFYKALTKRAEVQELFESFSAD
GQKLTLLEFLDFLQEEQKERDCTSELALELIDRYEPSDSGASEEDPGEGEEVNT"
BASE COUNT 643 a 575 c 706 g 528 t
ORIGIN
1 acacctctcc ccttcttact gcttccctcc ggctataact tgccagtcac agcagccagc
61 tgctgtagaa gaggggagga aacaagccag tgcaagggga gcaaaagaga aaaggagcca
121 ggctgggctt cctgatccca cagcatcgca gagctcggga ggcacagctc acagacacag
181 gaaacacagg actgctattc tgctctcctg cccacggtga tctggtgcca gctggtggaa
241 cagtgggtga tggcgtccct gctgcaagac cagctgacca ctgatcagga cttgctgctg
301 atgcaggaag gcatgccgat gcgcaaggtg aggtccaaaa gctggaagaa gctaagatac
361 ttcagacttc agaatgacgg catgacagtc tggcatgcac ggcaggccag gggcagtgcc
421 aagcccagct tctcaatctc tgatgtggag acaatacgta atggccatga ttccgagttg
481 ctgcgtagcc tggcagagga gctccccctg gagcagggct tcaccattgt cttccatggc
541 cgccgctcca acctggacct gatggccaac agtgttgagg aggcccagat atggatgcga
601 gggctccagc tgttggtgga tcttgtcacc agcatggacc atcaggagcg cctggaccaa
661 tggctgagcg attggtttca acgtggagac aaaaatcagg atggtaagat gagtttccaa
721 gaagttcagc ggttattgca cctaatgaat gtggaaatgg accaagaata tgccttcagt
781 ctttttcagg cagcagacac gtcccagtct ggaaccctgg aaggagaaga attcgtacag
841 ttctataagg cattgactaa acgtgctgag gtgcaggaac tgtttgaaag tttttcagct
901 gatgggcaga agctgactct gctggaattt ttggatttcc tccaagagga gcagaaggag
961 agagactgca cctctgagct tgctctggaa ctcattgacc gctatgaacc ttcagacagt
1021 ggagcttcgg aggaagatcc tggtgaaggg gaagaagtta acacttgagg aagacctgga
1081 atatgaggaa gaggaagcag aacctgagtt ggaagagtca gaattggcgc tggagtccca
1141 gtttgagact gagcctgagc cccaggagca gaaccttcag aataaggaca aaaagaagaa
1201 atccaagccc atcttgtgtc cagccctctc ttccctggtt atctacttga agtctgtctc
1261 attccgcagc ttcacacatt caaaggagca ctaccacttc tacgagatat catctttctc
1321 tgaaaccaag gccaagcgcc tcatcaagga ggctggtcag gaccaaaatg gagggatggg
1381 gagggaagtg ggatggatag gttcaggcct gatggactgg caggtaagtc ccaagaaaaa
1441 agacaaggta gctaaggaga gatgaaggag ttcagaaact ccttagagca gacaagggca
1501 gaggagttat gaatagtggc tcaagggtct aggggcagga aagctggtct ggatggacag
1561 agtagagagg cacagtgaaa ctttctggag ccagcttcag atgctggaga gaagggtgaa
1621 gagtaggcag ggtccttggg actagggaag tgggagattc caccccactt ccatctccct
1681 ctctataccc ttttacaggc aatgagtttg tgcagcacaa tacttggcag ttaagccgtg
1741 tgtatcccag cggcctgagg acagactctt ccaactacaa cccccaggaa ctctggaatg
1801 caggctgcca gatggtggcc atgaatatgc agactgcagg gcttgaaatg gacatctgtg
1861 atgggcattt ccgccagaat ggcggctgtg gctatgtgct gaagccagac ttcctgcgtg
1921 atatccagag ttctttccac cctgagaagc ccatcagccc tttcaaagcc cagactctct
1981 taatccaggt gatcagcggt cagcaactcc ccaaagtgga caagaccaaa gaggggtcca
2041 ttgtggatcc actggtgaaa gtgcagatct ttggcgttcg tctagacaca gcacggcagg
2101 agaccaacta tgtggagaac aatggtttta atccatactg ggggcagaca ctatgtttcc
2161 gggtgctggt gcctgaactt gccatgctgc gttttgtggt aatggattat gactggaaat
2221 cccgaaatga ctttattggt cagtacaccc tgccttggac ctgcatgcaa caaggttacc
2281 gccacattca cctgctgtcc aaagatggca tcagcctccg cccagcttcc atctttgtgt
2341 atatctgcat ccaggaaggc ctggaggggg atgagtcctg aggtgggcat ttcacgggaa
2401 gggttggtgt gctggcttta gacggggaga aacatctgga aggatgctcg ag
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