LOCUS AY500994 4049 bp mRNA linear HUM 12-FEB-2004
DEFINITION Homo sapiens angiogenic factor VG5Q mRNA, complete cds.
ACCESSION AY500994
VERSION AY500994.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4049)
AUTHORS Tian,X.-L., Kadaba,R., You,S.-A., Liu,M., Timur,A.A., Yang,L.,
Chen,Q., Szafranski,P., Rao,S., Wu,L., Housman,D.E.,
DiCorleto,P.E., Dirscoll,D.J., Borrow,J. and Wang,Q.
TITLE Identification of an angiogenic factor that when mutated causes
susceptibility to Klippel-Trenaunay syndrome
JOURNAL Nature 427 (6975), 640-645 (2004)
PUBMED 14961121
REFERENCE 2 (bases 1 to 4049)
AUTHORS Tian,X.-L. and Wang,Q.
TITLE Direct Submission
JOURNAL Submitted (12-DEC-2003) Center for Molecular Genetics-ND40, The
Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH
44195, USA
FEATURES Location/Qualifiers
source 1..4049
/db_xref="H-InvDB:HIT000255016"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="5"
/map="5q13.3"
/tissue_type="endothelium; vascular smooth muscle"
CDS 302..2446
/codon_start=1
/product="angiogenic factor VG5Q"
/protein_id="AAR97615.1"
/translation="MASEAPSPPRSPPPPTSPEPELAQLRRKVEKLERELRSCKRQVR
EIEKLLHHTERLYQNAESNNQELRTQVEELSKILQRGRNEDNKKSDVEVQTENHAPWS
ISDYFYQTYYNDVSLPNKVTELSDQQDQAIETSILNSKDHLQVENDAYPGTDRTENVK
YRQVDHFASNSQEPASALATEDTSLEGSSLAESLRAAAEAAVSQTGFSYDENTGLYFD
HSTGFYYDSENQLYYDPSTGIYYYCDVESGRYQFHSRVDLQPYPTSSTKQSKDKKLKK
KRKDPDSSATNEEKDLNSEDQKAFSVEHTSCNEEENFANMKKKAKIGIHHKNSPPKVT
VPTSGNTIESPLHENISNSTSFKDEKIMETDSEPEEGEITDSQTEDSYDEAITSEGNV
TAEDSEDEDEDKIWPPCIRVIVIRSPVLQIGSLFIITAVNPATIGREKDMEHTLRIPE
VGVSKFHAEIYFDHDLQSYVLVDQGSQNGTIVNGKQILQPKTKCDPYVLEHGDEVKIG
ETVLSFHIHPGSDTCDGCEPGQVRAHLRLDKKDESFVGPTLSKEEKELERRKELKKIR
VKYGLQNTEYEDEKTLKNPKYKDRAGKRREQVGSEGTFQRDDAPASVHSEITDSNKGR
KMLEKMGWKKGEGLGKDGGGMKTPIQLQLRRTHAGLGTGKPSSFEDVHLLQNKNKKNW
DKARERFTENFPETKPQKDDPGTMPWVKGTLE"
BASE COUNT 1315 a 775 c 887 g 1071 t
ORIGIN
1 gcttatccga cgctcctccc tctgtctctg tagctggaga aggtagtttc caggaaagtt
61 ttccggtttg caggccgcgc acatcgggca ggggccatcc tcggtcccct tgctcgttgc
121 tcgcagcccc gttcggctac aagtgagttt cagggcgtca tggccagggg ccaccgcggc
181 cagccgggtg tgaggctgcc tttcgctgcc cgcgcgctcc agtggtctct gggtccgccg
241 gcgtccgttt cggcctgaac gcagcccctc cgcggcgacg agcagtctcg cgccggagct
301 catggcctcg gaggcgccgt ccccgccgcg gtcgccgccg ccgcccacct cccccgagcc
361 tgagctggcc cagctaaggc ggaaggtgga gaagttggaa cgtgaactgc ggagctgcaa
421 gcggcaggtg cgggagatcg agaagctgct gcatcacaca gaacggctgt accagaacgc
481 agaaagcaac aaccaggagc tccgcacgca ggtggaagaa ctcagtaaaa tactccaacg
541 tgggagaaat gaagataata aaaagtctga tgtagaagta caaacagaga accatgctcc
601 ttggtcaatc tcagattatt tttatcagac gtactacaat gacgttagtc ttccaaataa
661 agtgactgaa ctgtcagatc aacaagatca agctatcgaa acttctattt tgaattctaa
721 agaccattta caagtagaaa atgatgctta ccctggtacc gatagaacag aaaatgttaa
781 atatagacaa gtggaccatt ttgcctcaaa ttcacaggag ccagcatctg cattagcaac
841 agaagatacc tccttagaag gctcatcatt agctgaaagt ttgagagctg cagcagaagc
901 ggctgtatca cagactggat ttagttatga tgaaaatact ggactgtatt ttgaccacag
961 cactggtttc tattatgatt ctgaaaatca actctattat gatccttcca ctggaattta
1021 ttactattgt gatgtggaaa gtggtcgtta tcagtttcat tctcgagtag atttgcaacc
1081 ttatccgact tctagcacaa aacaaagtaa agataaaaaa ttgaagaaga aaagaaaaga
1141 tccagattct tctgcaacaa atgaggaaaa ggatttgaac tcagaggatc aaaaagcctt
1201 cagtgttgaa catacaagct gcaatgagga agaaaatttc gcaaatatga aaaagaaggc
1261 caaaataggc attcatcaca aaaatagtcc ccccaaagtc actgttccaa ctagtggaaa
1321 tactatagag tctcctcttc atgaaaacat ctctaattca acatcattta aagatgagaa
1381 aatcatggag actgatagtg aaccagagga aggtgaaatt acagactctc agactgagga
1441 tagttatgac gaagccatta ccagtgaagg caatgtaact gcagaagata gtgaggatga
1501 agatgaagac aaaatctggc ccccatgtat tagagtaatt gtcattagat cacctgtgtt
1561 gcagatagga tcactcttta tcattactgc tgtaaaccct gctacaattg gaagagaaaa
1621 ggatatggaa catactctcc gaatccctga agttggtgtc agtaagtttc atgcagaaat
1681 ttattttgac catgacttac aaagttatgt ccttgtggat caaggcagtc aaaatggcac
1741 aattgttaat ggaaaacaga ttcttcagcc gaaaactaaa tgtgaccctt acgtacttga
1801 gcatggagat gaagtcaaaa ttggagaaac tgtcttatcc tttcacattc atcctggcag
1861 tgatacctgt gatggctgtg aaccagggca ggttagagcc caccttcgcc ttgataagaa
1921 agatgaatct tttgttggtc caacactaag taaggaggaa aaagagttgg aaagaagaaa
1981 agaattaaag aaaatacgag taaaatatgg tttacagaat acagaatacg aagatgaaaa
2041 gacattgaag aatccaaaat ataaagatag agctggaaaa cgtagggagc aggttggaag
2101 tgaaggaact ttccaaagag atgatgctcc tgcatctgtt cattctgaaa ttactgatag
2161 caacaaaggt cggaagatgt tggagaagat gggttggaag aaaggagagg gcctggggaa
2221 ggatggtgga ggaatgaaaa cgccgatcca gcttcagctt cggcgaacac atgcaggctt
2281 ggggacaggc aaaccatcct catttgaaga tgttcacctt ctccaaaaca agaacaaaaa
2341 aaactgggac aaagcacgag agcggtttac tgaaaacttc ccagaaacta agcctcaaaa
2401 agatgaccca gggaccatgc cttgggtaaa agggacttta gagtgaaggc taatcataga
2461 aaaaaaacct ctagtttttt taaaaataga atttggaaac ttattttttc tccccaaaag
2521 aatcagcagc acaggggaac tatgtcacag tttacctctt cctgattcag aaatgtgtat
2581 ggtttgcagc ttttaaaaac cattttttta aaactaataa atagtgactg aaccaattta
2641 tgcagtaaat agactaaagt tcacagggca cggatgagtt tatcaaactt cgttatttta
2701 tcttcattta caacatccat ataagcaact agccatataa gcaaaattca tagaactact
2761 aatgacttaa gtgtacatct gttcttgtct ccatatattc atgtaagatg cacaacaaaa
2821 gaaacatcag aagtttataa aaataaatct gactatacgc atcctcattt attcccttta
2881 gaacctaggt aaaaaatgtt gcgaaaacat gggtagtggc gcatacattt tgttatcctt
2941 gaaatagcct aagtaatgtt attgaagaac taatgaacag gtaacatatt gtagaaaatt
3001 agtctttcat tgttttcttc tgtgaagaat ctgttgctat gtactgtata ttcagcattt
3061 atatttggtt tgtttcatag ctaatgaggt atttagatat gaacaactga atacatattg
3121 aaatagtgtg ctggcttttg tagttttgat aaagaccatt gcaggcaatg gaattgtgcc
3181 agagaaatct gatttctagt acaaaaggaa tacttagcca gggcctcaag ctcaagatac
3241 ttattgaaaa catcctcaat tgcaataaaa acattataac atgaaaaaga gtgatttttt
3301 gaaccggtga tttaaatgta ttgatctgct ttgaattttc aagcagccag aattttctag
3361 tttaaattgg cagagttata acaaaggaga gcctcaaata ttagacaatt gcagtgcggc
3421 tttctgggca caggtgtcac tgctctgcca cctatcacta ttctttttct gttcagtttt
3481 tctctcaggt gtttgctggg gaaattaaca ctgggaactg acccttttct gggcagtgaa
3541 tgtaagctct agctccccca tctactataa agaaatgtct ttgagatgta gaaataagga
3601 atattctgaa aataaaaatt atacagtagt aaagataatt cagaaagaaa aagctacctg
3661 ttagaatttc cagtctaaat ggcacagggt agttacggag aaaaggggat ggagaaggag
3721 aaactatgac taaagatgag aggtatgaac gagttgtcag gttcctatgg gcttaagcta
3781 ggacaatcag gccctaaact ccaaatttgg ataaaatatc tctttgcatt cttcttggcc
3841 acctgcatag tctgacacat acgtatgtac agttagactt gcaggctgca ggagtgccct
3901 gcattgtttc ttttaattag aaaataaaag tattagtcta aatgtggntc ttgtgctggt
3961 gccctgtata tatgtaacaa tataggaccc cctccaaata ggttttgctt ctggtgaatc
4021 ttggtcattt ggttaagata tgactgtcc
//