LOCUS AY435431 1940 bp mRNA linear HUM 29-OCT-2003
DEFINITION Homo sapiens protein phosphatase 2C kappa mRNA, complete cds.
ACCESSION AY435431
VERSION AY435431.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1940)
AUTHORS Xu,J., Stagliano,N., Deponte,J. III, Rodrigue-Way,A., Golden,S.,
Katz,S., Jeyaseelan,R., Donoghue,M., Meyers,R., Gottfried,S.,
Wysong,D., McGovern,K., Pollman,M., Breitbart,R.E. and Acton,S.
TITLE Protein phosphatase 2C kappa is upregulated in heart failure and
attenuates agonist-induced cardiomyocyte hypertrophy
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1940)
AUTHORS Acton,S. and Xu,J.
TITLE Direct Submission
JOURNAL Submitted (10-OCT-2003) Cardiovascular, Millennium Pharmaceuticals,
Inc., 75 Sidney St., Cambridge, MA 02139, USA
FEATURES Location/Qualifiers
source 1..1940
/db_xref="H-InvDB:HIT000254687"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 391..1509
/note="PP2C kappa"
/codon_start=1
/product="protein phosphatase 2C kappa"
/protein_id="AAR06213.1"
/translation="MSTAALITLVRSGGNQVRRRVLLSSRLLQDDRRVTPTCHSSTSE
PRCSRFDPDGSGSPATWDNFGIWDNRIDEPILLPPSIKYGKPIPKISLENVGCASQIG
KRKENEDRFDFAQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMDLLPKEKNLETLL
TLAFLEIDKAFSSHARLSADATLLTSGTTATVALLRDGIELVVASVGDSRAILCRKGK
PMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKTSGVIA
EPETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPNEAAHAVTEQAIQYG
TEDNSTAVVVPFGAWGKYKNSEINFSFSRSFASSGRWA"
BASE COUNT 522 a 411 c 481 g 526 t
ORIGIN
1 gtcaaatagc agccgcgggg aggctcgttc ccatcggcat ctgtgactgg ctgcgatcga
61 gggcccgggc ggccggccag ccgtctcgcc gagtgcggac tggccggatc tgctgtcagt
121 cagcgggaac agacttctcc ctctccatct ggtcaactgc gggagaaaaa ttttcgagaa
181 tttccagcag gcaaggcagt ggccgctttg actgcttgct tcggagatcc gagacgacgg
241 agaaggcact cttatttacc gaccaagaaa gctcctcccc cgtcctccgt tagctaatta
301 aaacattttt cagggacgta gccatccaga gacattccat tattgttcca ttgacctttc
361 cctcatcact gagtcctttg gagctgagtt atgtcaacag ctgccttaat tactttggtc
421 agaagtggtg ggaaccaggt gagaaggaga gtgctgctaa gctcccgcct gctgcaggac
481 gacaggcggg tgacacccac gtgccacagc tccacttcag agcctaggtg ttctcggttt
541 gacccagatg gtagtgggag tccagctacc tgggacaatt ttgggatctg ggataaccgc
601 attgatgagc caattctgct gccacccagc attaagtatg gcaagccaat tcccaaaatc
661 agcttggaaa atgtggggtg cgcctcacag attggcaaac ggaaagagaa tgaagatcgg
721 tttgacttcg ctcagctgac agatgaggtc ctgtactttg cagtgtatga tggacacggt
781 ggacctgcag cagctgattt ctgtcatacc cacatggaga aatgtattat ggatttgctt
841 cctaaggaga agaacttgga aactctgttg accttggctt ttctagaaat agataaagcc
901 ttttcgagtc atgcccgcct gtctgctgat gcaactcttc tgacctctgg gactactgca
961 acagtagccc tattgcgaga tggtattgaa ctggttgtag ccagtgttgg ggacagccgg
1021 gctattttgt gtagaaaagg aaaacccatg aagctgacca ttgaccatac tccagaaaga
1081 aaagatgaaa aagaaaggat caagaaatgt ggtggttttg tagcttggaa tagtttgggg
1141 cagcctcacg taaatggcag gcttgcaatg acaagaagta ttggagattt ggaccttaag
1201 accagtggtg tcatagcaga acctgaaact aagaggatta agttacatca tgctgatgac
1261 agcttcctgg tcctcaccac agatggaatt aacttcatgg tgaatagtca agagatttgt
1321 gactttgtca atcagtgcca tgatcccaac gaagcagccc atgcggtgac tgaacaggca
1381 atacagtacg gtactgagga taacagtact gcagtagtag tgccttttgg tgcctgggga
1441 aaatataaga actctgaaat caacttctca ttcagcagaa gctttgcctc cagtggacga
1501 tgggcctgat taccagctgg gacttagagt ttctgtgcaa cagtttttca ctgagcatgt
1561 caagaaactg ataagatcaa aaaggtctcc taactcacta gatcagcgca caagtcagtg
1621 taaaccactt agatagtagt tttttcataa atgctcatca tatttatgtt ccgctgtaca
1681 tgttcagtat aaatatatgt gtagtgaagc tactgtgagt ctttaaatgg aaagagcaaa
1741 tgagaagtgg tttggataca cttgatgaga gatgagagtg tcacattaat aatttttaag
1801 actcttaggc agctatgggt ttcttttgat catttttgtt ctttattcat ttgaacacgt
1861 ttttgaagtt cttcaaacta gtcagtttga attttgacag ctattcaata tgtgatctcc
1921 aagtttaaaa aatttttttt
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