LOCUS AY372528 1389 bp mRNA linear HUM 01-JUN-2005
DEFINITION Homo sapiens tissue-type liver endomannosidase mRNA, complete cds.
ACCESSION AY372528
VERSION AY372528.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1389)
AUTHORS Hamilton,S.R., Li,H., Wischnewski,H., Prasad,A.,
Kerley-Hamilton,J.S., Mitchell,T., Walling,A.J., Davidson,R.C.,
Wildt,S. and Gerngross,T.U.
TITLE Intact {alpha}-1,2-endomannosidase is a typical type II membrane
protein
JOURNAL Glycobiology 15 (6), 615-624 (2005)
PUBMED 15677381
REFERENCE 2 (bases 1 to 1389)
AUTHORS Hamilton,S.R.
TITLE Direct Submission
JOURNAL Submitted (21-AUG-2003) GlycoFi, Inc., 21 Lafayette St., Suite 200,
Lebanon, NH 03766, USA
FEATURES Location/Qualifiers
source 1..1389
/db_xref="H-InvDB:HIT000253321"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="liver"
CDS 1..1389
/note="glycosidase; hEndo"
/codon_start=1
/product="endomannosidase"
/protein_id="AAQ75077.1"
/translation="MAKFRRRTCIILALFILFIFSLMMGLKMLRPNTATFGAPFGLDL
LPELHQRTIHLGKNFDFQKSDRINSETNTKNLKSVEITMKPSKASELNLDELPPLNNY
LHVFYYSWYGNPQFDGKYIHWNHPVLEHWDPRIAKNYPQGRHNPPDDIGSSFYPELGS
YSSRDPSVIETHMRQMRSASIGVLALSWYPPDVNDENGEPTDNLVPTILDKAHKYNLK
VTFHIEPYSNRDDQNMYKNVKYIIDKYGNHPAFYRYKTKTGNALPMFYVYDSYITKPE
KWANLLTTSGSRSIRNSPYDGLFIALLVEEKHKYDILQSGFDGIYTYFATNGFTYGSS
HQNWASLKLICDKYNLIFIPSVGPGYIDTSIRPWNTQNTRNRINGKYYEIGLSAALQT
RPSLISITSFNEWHEGTQIEKAVPKRTSNTVYLDYRPHKPGLYLELTRKWSEKYSKER
ATYALDRQLPVS"
misc_feature 28..78
/note="Region: putative transmembrane domain; hydrophobic
region"
misc_feature 178..1386
/note="Region: putative catalytic domain"
BASE COUNT 452 a 282 c 250 g 405 t
ORIGIN
1 atggcaaagt ttcggagaag gacttgcatc attttggcac tttttattct atttattttc
61 tctctgatga tgggtttaaa aatgctgaga ccaaatacag ctacttttgg agctcctttt
121 ggacttgacc ttcttccaga acttcatcaa cgaactattc atttggggaa aaattttgat
181 ttccaaaaga gtgacagaat caacagtgaa acaaatacca agaatttaaa aagtgttgaa
241 atcactatga aaccttccaa agcctctgaa cttaacttgg atgaactacc acctctgaac
301 aattatctac atgtatttta ttacagttgg tatggaaatc cacaatttga tggtaaatat
361 atacattgga atcatccagt gttagagcat tgggacccta gaatagccaa gaattatcca
421 caagggagac acaaccctcc agatgacatt ggctccagct tttatcctga attgggaagt
481 tacagttctc gggatccttc tgtcatagaa actcacatga gacaaatgcg ctcagcttca
541 attggtgtac tagccctctc ttggtaccca cctgatgtaa atgatgaaaa tggagaacct
601 actgataact tggtacccac tattttggat aaagctcata aatataacct aaaggttact
661 tttcacatag aaccatatag caatcgagat gatcaaaaca tgtacaaaaa tgtcaagtat
721 attatagaca aatatggaaa tcatccggcc ttttacaggt acaagacgaa gactggcaat
781 gctcttccta tgttttatgt ctatgattcc tatattacca agcctgaaaa atgggccaat
841 ctgttaacca cctcagggtc tcggagtatt cgcaattctc cttatgatgg actgtttatt
901 gcccttctgg tagaagaaaa acataagtat gatattcttc aaagtggttt tgatggaatt
961 tacacatatt ttgccacaaa tggctttact tatggctcat cacatcagaa ttgggctagc
1021 ctaaaattaa tttgtgataa atacaactta atatttatcc caagtgtggg cccaggatac
1081 atagatacca gcatccgtcc atggaacacg caaaacactc ggaaccgaat caatgggaag
1141 tattatgaaa ttggtctgag tgccgcactt cagacacgcc ccagcttaat ttctatcacc
1201 tcttttaatg agtggcatga aggaactcag attgaaaaag ctgttcccaa aagaaccagt
1261 aatacagtgt acctagatta ccgtcctcat aaaccaggtc tttacctaga actgactcgc
1321 aagtggtctg aaaaatacag taaggaaaga gcaacttatg cattagatcg ccagctgcct
1381 gtttcttaa
//