LOCUS AY367065 10434 bp mRNA linear HUM 05-JAN-2004
DEFINITION Homo sapiens abnormal spindle-like microcephaly-associated protein
(ASPM) mRNA, complete cds.
ACCESSION AY367065
VERSION AY367065.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 10434)
AUTHORS Zhang,J.
TITLE Evolution of the human ASPM gene, a major determinant of brain size
JOURNAL Genetics 165 (4), 2063-2070 (2003)
PUBMED 14704186
REFERENCE 2 (bases 1 to 10434)
AUTHORS Zhang,J.
TITLE Direct Submission
JOURNAL Submitted (13-AUG-2003) Department of Ecology and Evolutionary
Biology, University of Michigan, 830 North University Avenue, Ann
Arbor, MI 48109, USA
FEATURES Location/Qualifiers
source 1..10434
/db_xref="H-InvDB:HIT000253279"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..10434
/gene="ASPM"
CDS 1..10434
/gene="ASPM"
/codon_start=1
/product="abnormal spindle-like microcephaly-associated
protein"
/protein_id="AAR12641.1"
/translation="MANRRVGRGCWEVSPTERRPPAGLRGPAAEEEASSPPVLSLSHF
CRSPFLCFGDVLLGASRTLSLALDNPNEEVAEVKISHFPAADLGFSVSQRCFVLQPKE
KIVISVNWTPLKEGRVREIMTFLVNDVLKHQAILLGNAEEQKKKKRSLWDTIKKKKIS
ASTSHNRRVSNIQNVNKTFSVSQKVDRVRSPLQACENLAMNEGGPPTENNSLILEENK
IPISPISPAFNECHGATCLPLSVRRSTTYSSLHASENRELLNVHSANVSKVSFNEKAV
TETSFNSVNVNGQRGENSKLSLTPNCSSTLNITQSQIHFLSPDSFVNNSHGANNELEL
VTCLSSDMFMKDNSQPVHLESTIAHEIYQKILSPDSFIKDNYGLNQDLESESVNPILS
PNQFLKDNMAYMCTSQQTCKVPLSNENSQVPQSPEDWRKSEVSPRIPECQGSKSPKAI
FEELVEMKSNYYSFIKQNNPKFSAVQDISSHSHNKQPKRRPILSATVTKRKATCTREN
QTEINKPKAKRCLNSAVGEHEKVINNQKEKEDFHSYLPIIDPILSKSKSYKNEVTPSS
TTASVARKRKSDGSMEDANVRVAITEHTEVREIKRIHFSPSEPKTSAVKKTKNVTTPI
SKRISNREKLNLKKKTDLSIFRTPISKTNKRTKPIIAVAQSSLTFIKPLKTDIPRHPM
PFAAKNMFYDERWKEKQEQGFTWWLNFILTPDDFTVKTNISEVNAATLLLGIENQHKI
SVPRAPTKEEMSLRAYTARCRLNRLRRAACRLFTSEKMVKAIKKLEIEIEARRLIVRK
DRHLWKDVGERQKVLNWLLSYNPLWLRIGLETTYGELISLEDNSDVTGLAMFILNRLL
WNPDIAAEYRHPTVPHLYRDGHEEALSKFTLKKLLLLVCFLDYAKISRLIDHDPCLFC
KDAEFKASKEILLAFSRDFLSGEGDLSRHLGLLGLPVNHVQTPFDEFDFAVTNLAVDL
QCGVRLVRTMELLTQNWDLSKKLRIPAISRLQKMHNVDIVLQVLKSRGIELSDEHGNT
ILSKDIVDRHREKTLRLLWKIAFAFQVDISLNLDQLKEEIAFLKHTKSIKKTISLLSC
HSDDLINKKKGKRDSGSFEQYSENIKLLMDWVNAVCAFYNKKVENFTVSFSDGRVLCY
LIHHYHPCYVPFDAICQRTTQTVECTQTGSVVLNSSSESDDSSLDMSLKAFDHENTSE
LYKELLENEKKNFHLVRSAVRDLGGIPAMINHSDMSNTIPDEKVVITYLSFLCARLLD
LRKEIRAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAAL
VIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQ
SRIRMIIAVTSYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQ
RKMQSQVKATVILQRAFREWHLRKQAKEENSAIIIQSWYRMHKELRKYIYIRSCVVII
QKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLK
AHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQRQKYKKMKKAAV
IIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRA
YVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYM
QMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNY
YHAYKAQVNQRKNFLQVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYNKRV
KYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVRKQIRREHQA
ALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMW
KGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHL
YLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQ
RWYRGIKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQS
RISYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQ
TAATLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMKERNIQFQRYNKLRHSVIYIQA
IFRGKKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHL
QFLQVQNAVIKIQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYRALKQASVVI
QQQYQANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLL
VRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLRKAAITIQSSYRRLMVKKKLQEM
QRAAVLIQATFRMHRTYITFQTWKHASILIQQHYRTYRAAKLQRENYIRQWHSAVVIQ
AAYKGMKARQLLREKHKASIVIQSTYRMYRQYCFYQKLQWATKIIQEKYRANKKKQKV
FQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSI
QRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKK
TAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTIQAAFRGMKVRQKLKNVSEEKMAAIV
NQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFCRM
VTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAA
VVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWR
RYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQGCFYTKLERTRFLNVRA
SAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGYKGRQVFLRQKSAALIIQ
KYIRAREAGKHERIKYIEFKKSTVILQALVRGWLVRKRFLEQRAKIRLLHFTAAAYYH
LNAVRIQRAYKLYLAVKNANKQVNSVICIQRWFRARLQEKRFIQKYHSIKKIEHEGQE
CLSQRNRAASVIQKAVRHFLLRKKQEKFTSGIIKIQALWRGYSWRKKNDCTKIKAIRL
SLQVVNREIREENKLYKRTALALHYLLTYKHLSAILEALKHLEVVTRLSPLCCENMAQ
SGAISKIFVLIRSCNRSIPCMEVIRYAVQVLLNVSKYEKTTSAVYDVENCIDILLELL
QIYREKPGNKVADKGGSIFTKTCCLLAILLKTTNRASDVRSRSKVVDRIYSLYKLTAH
KHKMNTERILYKQKKNSSISIPFIPETPVRTRIVSRLKPDWVLRRDNMEEITNPLQAI
QMVMDTLGIPY"
BASE COUNT 3760 a 1831 c 2020 g 2823 t
ORIGIN
1 atggcgaacc ggcgagtggg gcgaggctgc tgggaagtga gcccgaccga gcggaggccg
61 cccgcggggc tgcggggccc cgcggccgag gaggaggcgt cttccccgcc ggtcctgtct
121 ctcagccact tctgcaggtc tcctttcctt tgcttcgggg acgttctcct gggagcctca
181 cggacgctgt ctctggccct agacaaccct aacgaggagg tggcagaagt gaagatctcc
241 cacttcccgg ccgcggacct gggcttcagt gtgtcgcagc gctgtttcgt gttgcagcct
301 aaagagaaaa ttgttatttc tgttaactgg acaccactca aagaaggccg agtaagagag
361 attatgacat ttcttgtaaa tgatgttctg aaacaccaag ctatattact aggaaatgca
421 gaagagcaga aaaagaaaaa gaggagtctt tgggatacca ttaaaaagaa gaaaatttca
481 gcctctacaa gtcacaacag aagggtttca aatattcaga atgttaataa aacatttagt
541 gtttcccaaa aagttgacag agttaggagc ccactacaag cttgtgaaaa cttggctatg
601 aatgaaggcg gtcccccaac agaaaacaat tctttaatac ttgaagaaaa taaaataccc
661 atatcaccta ttagccctgc tttcaatgaa tgccatggtg caacttgctt gccactctct
721 gtacgtcgat ctactaccta ctcatctctt catgcatcag aaaataggga actattaaat
781 gtacacagtg ccaacgtttc aaaagtttct tttaatgaga aagctgtaac tgaaacttcc
841 tttaattctg taaatgttaa tggccaaaga ggagagaata gtaaacttag tcttaccccc
901 aactgttctt caactttgaa cattacacaa agccaaatac attttctaag tccagattct
961 tttgtaaata atagtcatgg agctaataat gaactagaat tagtaacatg tctttcatca
1021 gatatgttta tgaaagataa ttcacagcct gtgcatttgg aatcaacaat tgcacatgaa
1081 atttatcaga aaattttaag tccagattct ttcataaaag ataattatgg actaaatcag
1141 gatctagaat cagagtcagt taatcctatt ttatccccta atcaattttt aaaagataac
1201 atggcatata tgtgtacatc tcagcaaaca tgtaaagtac cattatcaaa tgaaaattct
1261 caagtcccac agtctcctga agattggaga aaaagtgaag tttcgccacg tattcctgaa
1321 tgtcagggtt caaaatctcc caaagctatt tttgaagaac tagtagaaat gaagtcaaat
1381 tactacagtt ttataaaaca aaataatcct aaattttctg cagttcagga tatttctagt
1441 catagccaca ataaacaacc taagagacgt ccaatacttt ctgccactgt tactaaaagg
1501 aaggccacct gtaccagaga aaaccaaact gagattaata aaccaaaagc aaaaagatgt
1561 ctcaacagtg cagtgggtga acatgaaaaa gtaataaata atcaaaagga aaaagaagat
1621 tttcattctt atcttccaat tatagatcca atattaagta aatctaagag ttataaaaac
1681 gaggtaacac cctcttcgac aacagcttca gttgctcgga aaagaaagag cgatggaagc
1741 atggaagatg caaatgtgag agttgcaatt acagaacata cagaagtgcg agaaatcaaa
1801 agaatccatt tttctccctc agagcctaaa acatcagctg ttaagaaaac aaaaaatgtg
1861 acaacaccca tctcaaaacg tattagcaac agagagaaat taaacctgaa gaagaaaact
1921 gatttatcaa tattcagaac tccaatttct aaaacaaaca aaaggacaaa acccattatc
1981 gctgtggcac agtccagttt gaccttcata aaaccattaa aaacagatat tcccagacac
2041 ccgatgccat ttgctgcaaa aaacatgttt tatgatgaac gctggaagga aaagcaggaa
2101 cagggcttca cttggtggtt aaattttata ttaacccctg atgacttcac tgtaaaaaca
2161 aatatttctg aagtaaatgc tgctactctt cttttgggaa tagagaatca acataaaata
2221 agtgttccta gagcacctac aaaagaggaa atgtctctca gagcttatac tgctcggtgt
2281 aggttaaaca gactacgtcg tgcagcatgc cgtttgttta cttctgaaaa aatggttaaa
2341 gctattaaaa agcttgaaat tgaaattgaa gctaggcggt taattgttcg aaaagataga
2401 cacctatgga aagatgtggg agaacgtcag aaagtcctga attggctgtt gtcctacaat
2461 cctttgtggc ttcgaattgg tctagagaca acttatggag aactcatatc tttggaagat
2521 aacagtgatg tcacagggtt ggctatgttt attctgaatc gcctactttg gaatcctgat
2581 atagcagctg agtatagaca ccccactgtt cctcacctgt atagagatgg tcatgaagaa
2641 gctttgtcca agtttacatt gaaaaagtta ttgttgttgg tctgttttct tgattatgct
2701 aaaatttcca gactcattga tcatgatcct tgtctcttct gtaaagatgc cgaattcaag
2761 gctagtaaag aaatcctttt ggctttttca cgagatttcc taagtggtga aggtgacctt
2821 tcccgtcacc ttggcttatt gggattacct gttaaccatg ttcagacacc atttgatgaa
2881 tttgattttg ccgttacaaa tcttgccgta gacttgcaat gtggagtgcg ccttgtgcga
2941 accatggaac ttctcacaca gaactgggac ctctcaaaga aactcaggat tccggcaata
3001 agtcgtcttc aaaagatgca caatgttgac attgttcttc aagttcttaa atcacgagga
3061 attgaattaa gtgatgagca tggaaataca attctatcta aggatattgt ggataggcac
3121 agagaaaaaa ctctcaggtt gctttggaaa atagcgtttg cttttcaggt ggatatttcc
3181 cttaacttag atcaattaaa ggaagaaatt gcctttctaa aacacacaaa gagtataaag
3241 aaaacaatat ctctactatc atgccattct gatgatctta ttaataagaa aaaaggcaaa
3301 agggatagtg gttcctttga acaatatagt gaaaacataa agttattgat ggattgggta
3361 aatgctgttt gtgccttcta taataaaaag gtggagaatt ttacagtgtc tttctcagac
3421 ggccgtgtgt tatgttacct gatccaccat taccatcctt gctatgtgcc atttgacgct
3481 atatgtcagc gtactactca aactgtggaa tgtacgcaaa ctggttcagt ggtattaaat
3541 tcatcatctg aatctgatga cagttctctg gatatgtcac ttaaagcatt tgatcatgaa
3601 aatacttcag agctatacaa agagctccta gaaaatgaaa agaaaaattt tcacttggtt
3661 aggtctgcag ttagagacct tggtggaata cctgctatga ttaatcattc agatatgtca
3721 aatacaattc cagatgaaaa ggtggttatt acctatttgt catttctttg tgcaaggctt
3781 ttggatcttc gtaaagaaat aagagctgct cgactcatac aaacaacatg gagaaaatat
3841 aaactaaaaa cagatctcaa acgccatcag gagagagaga aagctgcaag aattattcaa
3901 ttggctgtaa tcaattttct agcaaaacaa agattgagaa aaagagttaa tgcagcactc
3961 gtcattcaga aatattggcg aagagtctta gcacagagaa aattattaat gttaaaaaag
4021 gaaaagctgg aaaaagttca aaataaagca gcatcactta ttcagggata ttggagaaga
4081 tattccacta gacaaagatt tctgaaattg aaatattatt caatcatcct gcaatctagg
4141 ataagaatga taattgctgt tacatcttat aaacgatatc tttgggctac agttacaatt
4201 cagaggcatt ggcgtgctta tttaagaaga aaacaagatc aacaaagata tgaaatgcta
4261 aaatcatcaa ctcttataat ccaatctatg ttcagaaaat ggaagcaacg taaaatgcaa
4321 tcacaagtaa aagctacagt aatattgcaa agagctttta gagaatggca tttaagaaaa
4381 caagctaaag aagaaaattc tgctattatc atacaatcat ggtatagaat gcataaagaa
4441 ttacggaaat atatttatat tagatcttgt gttgttatca ttcagaaaag atttcggtgc
4501 tttcaagccc aaaagttata taaaagaaga aaagagtcca tactaaccat ccagaagtac
4561 tacaaagcat atctgaaagg aaagattgag cgcaccaact atttgcagaa acgagctgca
4621 gccattcaat tacaagctgc ttttaggaga ctgaaagctc ataatttatg tagacaaatt
4681 agagctgctt gtgttattca gtcatactgg agaatgagac aagacagagt tcgattttta
4741 aaccttaaga agactattat caaatttcag gcacatgtaa gaaaacatca acaacgacag
4801 aaatataaga agatgaagaa agcagctgtt ataattcaga ctcatttccg agcttatatt
4861 tttgccatga aagttctagc atcttaccag aaaacacgct ctgctgtcat tgtgctgcag
4921 tctgcatata gagggatgca agccaggaaa atgtatattc acatcctcac atctgttata
4981 aagattcaat catattatcg tgcttatgtt tctaaaaagg aatttttgag cctaaaaaat
5041 gctacaataa aattgcagtc aactgttaag atgaaacaaa cacgtaaaca atatttgcat
5101 ttaagagcag ctgcactatt tatccagcaa tgttaccgtt ccaaaaaaat agctgcacaa
5161 aagagagaag agtatatgca gatgcgggaa tcttgtatca aactgcaagc atttgttaga
5221 ggataccttg tccgaaagca gatgaggtta caaagaaaag ctgttatttc actacagtct
5281 tatttcagaa tgagaaaggc tcggcagtat tatctgaaaa tgtataaagc aattattgtc
5341 attcagaatt actatcatgc atacaaagca caggtcaatc agaggaagaa cttcttgcaa
5401 gtcaaaaaag cagctacttg cttgcaagca gcttacagag gttataaagt acgccagcta
5461 atcaaacaac aatctatagc tgctcttaaa attcagtctg cttttagagg ctataataaa
5521 agggtaaaat atcaatctgt gcttcaatct ataataaaga ttcagagatg gtacagggcg
5581 tacaagactc ttcatgatac aagaacacat tttttgaaga caaaggcagc tgtgatttcc
5641 ctccagtctg cttatcgtgg ctggaaggtt cggaaacaga ttagaaggga acatcaagct
5701 gccttgaaga ttcagtctgc ttttagaatg gccaaggccc agaaacagtt tagattgttt
5761 aaaacagcag cattagtcat ccagcaaaat ttcagagcat ggactgcagg aaggaagcaa
5821 tgtatggagt atattgaact ccgtcatgcg gtactggtgc ttcaatctat gtggaaggga
5881 aaaacactga gaagacagct tcaaaggcaa cataaatgtg ctatcatcat acagtcatac
5941 tatagaatgc atgtgcaaca aaagaagtgg aaaatcatga aaaaagctgc tcttctgatt
6001 caaaagtatt atagggctta cagtattgga agagaacaga atcatttata tttgaaaaca
6061 aaagcagctg tagtaacttt acagtcagct tatcgtggta tgaaagtgag aaaaagaata
6121 aaggattgca acaaagcagc agtcactata cagtctaaat acagagctta caaaaccaaa
6181 aagaaatatg caacctatag agcttcagct attataattc agagatggta tcgaggtatt
6241 aaaattacaa accatcagca taaggagtat cttaatttga agaagacagc aattaaaatc
6301 caatctgttt atagaggtat tagagttaga agacatattc aacacatgca cagggcagcc
6361 acttttatta aagccatgtt taaaatgcat cagtcaagaa taagttacca tacaatgaga
6421 aaagcagcta ttgttattca agtaagatgt agagcatatt atcaaggtaa aatgcagcgt
6481 gaaaagtacc tgacaatttt gaaagctgtt aaagtccttc aggcaagttt tagaggagta
6541 agagttagac ggactcttag aaagatgcag actgcagcaa cactcattca gtcaaactac
6601 agaagataca gacagcaaac atactttaat aagttaaaga aaataacaaa aacagtacag
6661 caaagatact gggcaatgaa agaaagaaac atacaatttc aaaggtataa caaactgagg
6721 cattctgtaa tatacattca ggctattttt aggggaaaga aagctagaag acatttaaaa
6781 atgatgcata tagccgcaac tctcattcag aggagattta gaactctaat gatgagaaga
6841 agattcctct ctctcaagaa aactgctatt ttgattcaga gaaaatatcg ggcacatctt
6901 tgtacaaagc atcacttaca gttccttcag gtacaaaatg cagttattaa aatccagtca
6961 tcatacagaa gatggatgat aaggaaaagg atgcgagaga tgcacagggc tgctactttc
7021 atccagtcta ctttcagaat gcacagatta catatgagat atcgagcttt gaaacaggcc
7081 tccgttgtga tccaacagca ataccaagca aatagagctg caaaactgca gaggcagcat
7141 tatctcagac aaagacactc tgctgtgatc cttcaggctg cattcagggg tatgaaaact
7201 agaagacatt tgaagagtat gcattcctct gcaaccctta ttcagagtag gtttagatca
7261 ttactggtga ggagaagatt catttccctc aaaaaagcta ctatttttgt tcagaggaaa
7321 tatcgagcca ccatttgtgc caaacataaa ttgtaccaat tcttgcactt aagaaaggca
7381 gccattacaa tacagtcatc ttacagaaga ctgatggtaa agaagaagtt acaagaaatg
7441 caaagggctg cagttctcat tcaggctact ttcaggatgc acagaacata tattacattt
7501 cagacttgga aacatgcttc aattctaatt cagcaacatt atcgaacata tagagctgca
7561 aaattgcaaa gagaaaatta tatcagacaa tggcattctg ctgtggttat tcaggctgca
7621 tataaaggaa tgaaagcaag acaactttta agggaaaaac acaaagcttc tatcgtaata
7681 caaagcacct acagaatgta taggcagtat tgtttctacc aaaagcttca gtgggctaca
7741 aaaatcatac aagaaaaata tagagcaaat aaaaagaaac agaaagtatt tcaacacaat
7801 gaacttaaga aagagacttg tgttcaggca ggttttcagg acatgaacat aaaaaaacag
7861 attcaggaac agcaccaggc tgccattatt attcagaagc attgtaaagc ctttaaaata
7921 aggaagcatt atctccacct tagagcaaca gtagtttcta ttcaaagaag atacagaaaa
7981 ctaactgcag tgcgtaccca agcagttatt tgtatacagt cttattacag aggctttaaa
8041 gtacgaaagg atattcaaaa tatgcaccgg gctgccacac taattcagtc attctatcga
8101 atgcacaggg ccaaagttga ttatgaaaca aagaaaactg caattgtggt tatacagaat
8161 tattataggt tgtatgttag agtaaaaaca gaaagaaaaa actttttagc agttcagaaa
8221 tctgtacgaa ctattcaggc tgcttttaga ggcatgaaag ttagacaaaa attgaaaaat
8281 gtatcagagg aaaagatggc agccattgtt aaccaatctg cactctgctg ttacagaagt
8341 aaaactcagt atgaagctgt tcaaagtgaa ggtgttatga ttcaagagtg gtataaagct
8401 tctggccttg cttgttcaca ggaagcagag tatcattctc aaagtagggc tgcagtaaca
8461 attcaaaaag ctttttgtag aatggtcaca agaaaactgg aaacacagaa atgtgctgcc
8521 ctacggattc agttcttcct tcagatggct gtgtatcgga gaagatttgt tcagcagaaa
8581 agagctgcta tcactttaca gcattatttt aggacgtggc aaaccagaaa acagttttta
8641 ctatatagaa aagcagcagt ggttttacaa aatcactaca gagcatttct gtctgcaaaa
8701 catcaaagac aagtctattt acagatcaga agcagtgtta tcattattca agctagaagt
8761 aaaggattta tacagaaacg gaagtttcag gaaattaaaa atagcaccat aaaaattcag
8821 gctatgtgga ggagatatag agccaagaaa tatttatgta aagtgaaagc tgcctgcaag
8881 attcaagcct ggtatagatg ttggagagca cacaaagaat atctagctat attaaaagct
8941 gttaaaatta ttcaaggttg cttctatacc aaactagaga gaacacggtt tttgaatgtg
9001 agagcatcag caattatcat tcagagaaaa tggagagcta tacttcctgc aaagatagct
9061 catgaacact tcttaatgat aaaaagacat cgagctgctt gtttgatcca agcacattat
9121 agaggatata aaggaaggca ggtctttctt cggcagaaat ctgctgcttt gatcatacaa
9181 aaatatatac gagccaggga ggctggaaag catgaaagga taaaatatat tgaatttaaa
9241 aaatctacag ttatcctaca agcactggtg cgtggttggc tagtacgaaa aagattttta
9301 gaacagagag ccaaaattcg acttcttcac ttcactgcag ctgcatatta tcacctgaat
9361 gctgttagaa ttcaaagagc ctataaactt tacctggctg tgaagaatgc taacaagcag
9421 gttaattcag tcatctgtat tcagagatgg tttcgagcaa gattacaaga aaagagattt
9481 attcagaaat atcatagcat caaaaagatt gagcatgaag gtcaagaatg tctgagccag
9541 cgaaataggg ctgcatcagt aatacagaaa gcagtgcgcc attttctcct ccgtaaaaag
9601 caggaaaaat tcactagtgg aatcattaaa attcaggcat tatggagagg ctattcttgg
9661 aggaagaaaa atgattgtac aaaaattaaa gctatacgac taagtcttca agttgttaat
9721 agggagattc gagaagaaaa caaactctac aaaagaactg cacttgcact tcattacctt
9781 ttgacatata agcacctttc tgccattctt gaggccttaa aacacctaga ggtagttact
9841 agattgtctc cactttgttg tgagaacatg gcccagagtg gagcaatttc taaaatattt
9901 gttttgatcc gaagttgtaa tcgcagtatt ccttgtatgg aagtcatcag atatgctgtg
9961 caagtcttgc ttaatgtatc taagtatgag aaaactactt cagcagttta tgatgtagaa
10021 aattgtatag atatactatt ggagcttttg cagatatacc gagaaaagcc tggtaataaa
10081 gttgcagaca aaggcggaag catttttaca aaaacttgtt gtttgttggc tattttactg
10141 aagacaacaa atagagcctc tgatgtacga agtaggtcca aagttgttga ccgtatttac
10201 agtctctaca aacttacagc tcataaacat aaaatgaata ctgaaagaat actttacaag
10261 caaaagaaga attcttctat aagcattcct tttatcccag aaacacctgt aaggaccaga
10321 atagtttcaa gacttaagcc agattgggtt ttgagaagag ataacatgga agaaatcaca
10381 aatcccctgc aagctattca aatggtgatg gatacgcttg gcattcctta ttag
//