LOCUS AY366448 4801 bp mRNA linear HUM 19-DEC-2003
DEFINITION Homo sapiens chromosome 13 Rho GTPase activating protein mRNA,
complete cds.
ACCESSION AY366448
VERSION AY366448.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4801)
AUTHORS Nagaraja,G.M. and Kandpal,R.P.
TITLE Chromosome 13q12 encoded Rho GTPase activating protein suppresses
growth of breast carcinoma cells, and yeast two-hybrid screen shows
its interaction with several proteins
JOURNAL Biochem. Biophys. Res. Commun. 313 (3), 654-665 (2004)
PUBMED 14697242
REFERENCE 2 (bases 1 to 4801)
AUTHORS Ganachari,N.M. and Kandpal,R.P.
TITLE Direct Submission
JOURNAL Submitted (13-AUG-2003) Biological Sciences, Fordham University,
441 E. Fordham Road, Bronx, NY 10458, USA
FEATURES Location/Qualifiers
source 1..4801
/db_xref="H-InvDB:HIT000253259"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="13"
/map="13q12.3"
CDS 62..3403
/note="RhoGAP"
/codon_start=1
/product="Rho GTPase activating protein"
/protein_id="AAQ72791.1"
/translation="MFSQVPRTPASGCYYLNSMTPEGQEMYLRFDQTTRRSPYRMSRI
LARHQLVTKIQQEIEAKEACDWLRAAGFPQYAQLYEDSQFPINIVAVKNDHDFLEKDL
VEPLCRRLNTLNKCASMKLDVNFQRKKGDDSDEEDLCISNRWTFQRTSRRWSRVDDLY
TLLPRGDRNGSPGGTGMRNTTSSESVLTDLSEPEVCSIHSESSGGSDSRSQPGQCCTD
NPVMLDAPLVSSSLPQPPRDVLNHPFHPKNEKPTRARAKSFLKRMETLRGKGAHGRHK
GSGRTGGLVISGPMLQQEPESFKAMQCIQIPNGDLQNSPPPACRKGLPCSGKSSGESS
PSEHSSSGVSTPCLKERKCHEANKRGGMYLEDLDVLAGTALPDAGDQSRMHEFHSQEN
LVVHVPKDHKPGTFPKALSIESLSPTDSSNGVNWRTGSISLGREQVPGAREPRLMASC
HRASRVSIYDNVPGSHLYASTGDLLDLEKDDLFPHLDDILQHVNGLQEVVDDWSKDVL
PELQTHDTLVGEPGLSTFPSPNQITLDFEGNSVSEGRTTPSDVERDVTSLNESEPPGV
RDRRDSGVGASLTRPNRRLRWNSFQLSHQPRPAPASPHISSQTASQLSLLQRFSLLRL
TAIMEKHSMSNKHGWTWSVPKFMKRMKVPDYKDKAVFGVPLIVHVQRTGQPLPQSIQQ
ALRYLRSNCLDQVGLFRKSGVKSRIHALRQMNENFPENVNYEDQSAYDVADMVKQFFR
DLPEPLFTNKLSETFLHIYQYVSKEQRLQAVQAAILLLADENREVLQTLLCFLNDVVN
LVEENQMTPMNLAVCLAPSLFHLNLLKKESSPRVIQKKYATGKPDQKDLNENLAAAQG
LAHMIMECDRLFEVPHELVAQSRNSYVEAEIHVPTLEELGTQLEESGATFHTYLNHLI
QGLQKEAKEKFKGWVTCSSTDNTDLAFKKVGDGNPLKLWKASVEVEAPPSVVLNRVLR
ERHLWDEDFVQWKVVETLDRQTEIYQYVLNSMAPHPSRDFVVLRTWKTDLPKGMCTLV
SLSVEHEEAQLLGGVRAVVMDSQYLIEPCGSGKSRLTHICRIDLKGHSPEWYSKGFGH
LCAAEVARTRNSFQPLIAEGPETKI"
BASE COUNT 1322 a 1156 c 1208 g 1115 t
ORIGIN
1 gactggagac agacggcaac agccacaggc agactgaggt ggcaatagga aatctgccga
61 gatgttcagt caggtgccca ggaccccagc ctcaggctgc tactacctaa attccatgac
121 acctgagggc caggagatgt acttgcgatt tgatcagact acaagacgct ctccttacag
181 gatgagccgg attctagcac gccatcagct agtgactaaa attcaacaag aaattgaggc
241 aaaagaagca tgtgactggc tccgtgctgc cgggttcccg caatacgctc agttatatga
301 ggattcacaa tttcccatca acattgtggc tgtcaagaat gatcatgatt ttcttgaaaa
361 ggaccttgta gaacctcttt gcagacgact aaatacgttg aacaagtgtg cctcaatgaa
421 acttgatgtg aacttccaaa ggaaaaaggg tgacgactcc gatgaggaag atctttgtat
481 cagcaacaga tggactttcc aaagaaccag tcgcaggtgg tctcgtgtgg acgacctcta
541 cacgctgctc cctcgaggag acagaaatgg gtcaccggga ggcacgggga tgaggaacac
601 gaccagcagt gagagcgtcc tcacagacct gagcgagcct gaggtctgct ccattcacag
661 cgaaagcagt ggaggcagcg acagtcgcag ccagccgggc cagtgctgta cagacaaccc
721 ggtcatgctg gatgccccac tcgtcagcag cagcctccca cagcccccca gagatgtcct
781 caaccacccc ttccacccca agaatgagaa gcccacgagg gctagggcca aatcattttt
841 gaaacgcatg gaaacactcc gagggaaggg agcccacggg aggcataagg ggtctgggcg
901 gacaggtggc ctggtgatca gtgggcccat gttgcagcag gagccagagt cctttaaggc
961 tatgcagtgc atccaaatac caaatggaga tctccagaat tcgccgccac ctgcctgcag
1021 aaaagggctc ccatgctctg gcaagtcgag tggcgagagc agcccgtcgg agcacagcag
1081 cagcggggtg agcacgccct gcctgaagga acgcaagtgc cacgaggcca acaagcgcgg
1141 gggcatgtac ttggaggacc tagatgtgct ggcggggaca gcactgccgg atgcagggga
1201 ccaaagccgt atgcatgaat ttcactccca agagaatttg gtggtgcatg ttcccaagga
1261 tcacaaacca ggaacattcc ccaaggcact ttctattgaa agcctctctc ccacagatag
1321 tagcaatggg gttaattgga ggaccggtag catctccctg ggcagagagc aggtccctgg
1381 tgccagggag ccccggctca tggcgtcctg ccacagagcc agccgagtca gtatctatga
1441 caatgtccct ggctcccatc tgtatgccag cacaggagat cttttggact tggagaaaga
1501 tgaccttttc cctcacttgg atgacattct gcagcatgtc aatgggctcc aagaggtagt
1561 cgatgactgg tccaaagatg tcttgcctga actgcaaact catgatacat tggttgggga
1621 acctggctta tccacctttc catctcctaa tcagatcacc ttagattttg aaggtaactc
1681 tgtctcagaa ggtcggacga cacccagtga tgtggaaaga gatgtaacat ctcttaatga
1741 atctgagcct cctggggtca gagacaggag ggattctggt gtaggggcct ctctgaccag
1801 gccaaacagg cgactccgat ggaacagttt ccagctgtcg caccagcccc ggccggcccc
1861 agcatcgccc cacatcagca gccagacggc cagccagctg agcctgctcc agcgcttctc
1921 actgctccgc ctcacggcca tcatggagaa gcactccatg tccaacaagc acggctggac
1981 atggtcagtt ccaaagttca tgaagaggat gaaagttccc gactacaaag acaaggctgt
2041 ctttggcgtt cctctcatag tccacgtcca aagaacggga cagcccctgc ctcaaagtat
2101 tcagcaagca ctgagatatc tacgcagcaa ctgcctcgat caggtgggtc tttttcgcaa
2161 atcaggagtg aagtctcgaa tccatgccct tcgccaaatg aatgaaaact tccctgagaa
2221 cgtcaactat gaagaccagt ctgcttatga tgtggcggat atggtgaaac agttcttccg
2281 ggacctccct gagcctcttt tcaccaacaa gctcagtgag acctttctcc atatctatca
2341 gtatgtctcc aaagagcagc ggctgcaggc cgtgcaggcc gccatcctgc tactggccga
2401 tgagaacagg gaggtcctgc agacgctctt gtgtttcctg aacgacgtcg tcaacttggt
2461 ggaagagaat cagatgacgc ccatgaacct ggcagtgtgt ctggccccct ccctctttca
2521 tcttaattta ttgaagaaag aaagctctcc acgagtcata cagaagaaat atgccactgg
2581 gaagccagat caaaaggacc tcaacgagaa tctggcagca gctcaggggc tagcgcacat
2641 gatcatggaa tgcgacagac tttttgaggt tccacacgag ttggtggccc agtctcgtaa
2701 ctcgtatgtg gaggctgaga tccacgtgcc aaccctggaa gaattgggga cacagctgga
2761 ggagagtggg gcaactttcc acacttacct gaaccatctc atccagggcc tccagaaaga
2821 agccaaggag aagttcaaag gatgggtcac gtgctccagc acggacaata cagatcttgc
2881 tttcaaaaag gtgggcgacg ggaacccgct gaagctgtgg aaggcttctg tggaggtgga
2941 agcacccccc tcagtggtcc tgaaccgcgt gctgagagag cgccacctgt gggacgagga
3001 ctttgtgcag tggaaggttg tggaaactct agacaggcaa acagagatct accagtatgt
3061 gctgaacagc atggctcccc atccttccag agactttgtg gttctcagga cctggaaaac
3121 tgatttgccc aaaggaatgt gtaccctggt gtccctctcc gtggagcatg aggaagccca
3181 gctcctgggt ggtgtgcgag cagtggtgat ggactcgcag tacttgatag aaccgtgtgg
3241 ctctggcaag tcaagactga ctcacatctg caggatagac ctgaaaggtc actccccaga
3301 atggtacagc aaaggctttg gacatctgtg tgcagcagaa gttgccagga ctagaaactc
3361 tttccagccc ctcattgctg agggcccaga aactaaaatc tgacttttgc ccagtgtgac
3421 atcaaactca gggaagagga agctaaagtg acgagtgtgg cagagagtgt gcatgtgaga
3481 aagcgagaga aagaggaact gaaggacgcg gttaatgcct aaaaatggaa acgttaagaa
3541 gttggaatgt tggagatgca agaatttcca agaactttct tagccttcct ggagatgggt
3601 acatccctac taatataatt ttaaaatgag aactttatat atattactta aaattaaatg
3661 gactattcct tgtgcattgc ctaatttgct atttaaaggc ttctaagaag cgtataccta
3721 actgtaattt atgtatgtat agcatatgta catatgtgtg tatatctcca tctttactgt
3781 atatatgtaa aataccaatt ttatatagaa ttgtgtgttt tgaaaatgac ggtgtctgac
3841 tcagtgagtc ccttcctcac acagttcttt ccaagtggct ctgggcccca tctctccact
3901 gtcctgtaag ctgtgcagaa cctgctgcta acaccaaggt gtgaacatgc cctgatgcct
3961 aaccaaagat gagttaacca aaggaaaata acattaaagg agacttatgt gttaacgctt
4021 tgtttctgct attcaaaaac tgagagtgga gatctgggat aaagcaagga aataataatt
4081 actcctcctt aaagcaaatg ggggggtgag aagtcattac caaatttaaa gctagatgag
4141 gagttgccac tgggcccagt aagatggaat ttcagtgaga tatggaccac cggagtcagc
4201 gagagtgact gaaacagaag cgatacctct cgctcccatg cccatcacta cagaccccaa
4261 gtcaagatga atatcatagc ctttacttct tcacagccaa agggagcccc tgtgttgtct
4321 caagttttta taaatacatt tcataatgtt attaaatgtc attctatttg accagtggcc
4381 tatttggtca cagttaattg gtgttttctt attgcactga attcaactcc agacaccata
4441 caaagggaga tgatggccat tccacagggt ttttaactaa catgagacca aaactatgtt
4501 ctttgattag ttttagatag tataatcggg tttattaatt cttctgtgtt tcttcactag
4561 ccagtccaag ctacctatgc atttgaccca accttattta ttattgtaca gatgaagcga
4621 attgactccc tttagccaac tgctaatgga tcgaatgtgc tttttattgt aattcaacag
4681 ctatagagag aaagataact tattgtgtgt ttgatttcag ggagagagat tttctttggt
4741 catccataat agagattgat aagatttagc aactggtgtt ggagaaaaaa agaaaagcaa
4801 a
//