LOCUS AY358296 4199 bp mRNA linear HUM 03-OCT-2003
DEFINITION Homo sapiens clone DNA42663 TLR8 (UNQ249) mRNA, complete cds.
ACCESSION AY358296
VERSION AY358296.1
KEYWORDS FLI_CDNA.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4199)
AUTHORS Clark,H.F., Gurney,A.L., Abaya,E., Baker,K., Baldwin,D., Brush,J.,
Chen,J., Chow,B., Chui,C., Crowley,C., Currell,B., Deuel,B.,
Dowd,P., Eaton,D., Foster,J., Grimaldi,C., Gu,Q., Hass,P.E.,
Heldens,S., Huang,A., Kim,H.S., Klimowski,L., Jin,Y., Johnson,S.,
Lee,J., Lewis,L., Liao,D., Mark,M., Robbie,E., Sanchez,C.,
Schoenfeld,J., Seshagiri,S., Simmons,L., Singh,J., Smith,V.,
Stinson,J., Vagts,A., Vandlen,R., Watanabe,C., Wieand,D., Woods,K.,
Xie,M.H., Yansura,D., Yi,S., Yu,G., Yuan,J., Zhang,M., Zhang,Z.,
Goddard,A., Wood,W.I., Godowski,P. and Gray,A.
TITLE The secreted protein discovery initiative (SPDI), a large-scale
effort to identify novel human secreted and transmembrane proteins:
a bioinformatics assessment
JOURNAL Genome Res. 13 (10), 2265-2270 (2003)
PUBMED 12975309
REMARK Erratum:[Genome Res. 2003 Dec;13(12):2759]
REFERENCE 2 (bases 1 to 4199)
AUTHORS Clark,H.F.
TITLE Direct Submission
JOURNAL Submitted (01-AUG-2003) Department of Bioinformatics, Genentech,
Inc., 1 DNA Way, South San Francisco, CA 94080, USA
FEATURES Location/Qualifiers
source 1..4199
/db_xref="H-InvDB:HIT000252340"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="DNA42663"
gene 1..4199
/locus_tag="UNQ249"
CDS 57..3182
/locus_tag="UNQ249"
/note="PRO286"
/codon_start=1
/product="TLR8"
/protein_id="AAQ88663.1"
/translation="MENMFLQSSMLTCIFLLISGSCELCAEENFSRSYPCDEKKQNDS
VIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVQH
QNGNPGIQSNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYN
ITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPP
KLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASI
NIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIVSGAFLT
MLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQ
LPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKDTRQSYANSSSFQRH
IRKRRSTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIA
CLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSH
YFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILW
NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWT
LLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKH
LDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRL
VDVICASPGDQRGKSIVSLELTTCVSDVTAVILFFFTFFITTMVMLAALAHHLFYWDV
WFIYNVCLAKVKGYRSLSTSQTFYDAYISYDTKDASVTDWVINELRYHLEESRDKNVL
LCLEERDWDPGLAIIDNLMQSINQSKKTVFVLTKKYAKSWNFKTAFYLALQRLMDENM
DVIIFILLEPVLQHSQYLRLRQRICKSSILQWPDNPKAEGLFWQTLRNVVLTENDSRY
NNMYVDSIKQY"
BASE COUNT 1276 a 867 c 786 g 1270 t
ORIGIN
1 gggtaccatt ctgcgctgct gcaagttacg gaatgaaaaa ttagaacaac agaaacatgg
61 aaaacatgtt ccttcagtcg tcaatgctga cctgcatttt cctgctaata tctggttcct
121 gtgagttatg cgccgaagaa aatttttcta gaagctatcc ttgtgatgag aaaaagcaaa
181 atgactcagt tattgcagag tgcagcaatc gtcgactaca ggaagttccc caaacggtgg
241 gcaaatatgt gacagaacta gacctgtctg ataatttcat cacacacata acgaatgaat
301 catttcaagg gctgcaaaat ctcactaaaa taaatctaaa ccacaacccc aatgtacagc
361 accagaacgg aaatcccggt atacaatcaa atggcttgaa tatcacagac ggggcattcc
421 tcaacctaaa aaacctaagg gagttactgc ttgaagacaa ccagttaccc caaataccct
481 ctggtttgcc agagtctttg acagaactta gtctaattca aaacaatata tacaacataa
541 ctaaagaggg catttcaaga cttataaact tgaaaaatct ctatttggcc tggaactgct
601 attttaacaa agtttgcgag aaaactaaca tagaagatgg agtatttgaa acgctgacaa
661 atttggagtt gctatcacta tctttcaatt ctctttcaca cgtgccaccc aaactgccaa
721 gctccctacg caaacttttt ctgagcaaca cccagatcaa atacattagt gaagaagatt
781 tcaagggatt gataaattta acattactag atttaagcgg gaactgtccg aggtgcttca
841 atgccccatt tccatgcgtg ccttgtgatg gtggtgcttc aattaatata gatcgttttg
901 cttttcaaaa cttgacccaa cttcgatacc taaacctctc tagcacttcc ctcaggaaga
961 ttaatgctgc ctggtttaaa aatatgcctc atctgaaggt gctggatctt gaattcaact
1021 atttagtggg agaaatagtc tctggggcat ttttaacgat gctgccccgc ttagaaatac
1081 ttgacttgtc ttttaactat ataaagggga gttatccaca gcatattaat atttccagaa
1141 acttctctaa acttttgtct ctacgggcat tgcatttaag aggttatgtg ttccaggaac
1201 tcagagaaga tgatttccag cccctgatgc agcttccaaa cttatcgact atcaacttgg
1261 gtattaattt tattaagcaa atcgatttca aacttttcca aaatttctcc aatctggaaa
1321 ttatttactt gtcagaaaac agaatatcac cgttggtaaa agatacccgg cagagttatg
1381 caaatagttc ctcttttcaa cgtcatatcc ggaaacgacg ctcaacagat tttgagtttg
1441 acccacattc gaacttttat catttcaccc gtcctttaat aaagccacaa tgtgctgctt
1501 atggaaaagc cttagattta agcctcaaca gtattttctt cattgggcca aaccaatttg
1561 aaaatcttcc tgacattgcc tgtttaaatc tgtctgcaaa tagcaatgct caagtgttaa
1621 gtggaactga attttcagcc attcctcatg tcaaatattt ggatttgaca aacaatagac
1681 tagactttga taatgctagt gctcttactg aattgtccga cttggaagtt ctagatctca
1741 gctataattc acactatttc agaatagcag gcgtaacaca tcatctagaa tttattcaaa
1801 atttcacaaa tctaaaagtt ttaaacttga gccacaacaa catttatact ttaacagata
1861 agtataacct ggaaagcaag tccctggtag aattagtttt cagtggcaat cgccttgaca
1921 ttttgtggaa tgatgatgac aacaggtata tctccatttt caaaggtctc aagaatctga
1981 cacgtctgga tttatccctt aataggctga agcacatccc aaatgaagca ttccttaatt
2041 tgccagcgag tctcactgaa ctacatataa atgataatat gttaaagttt tttaactgga
2101 cattactcca gcagtttcct cgtctcgagt tgcttgactt acgtggaaac aaactactct
2161 ttttaactga tagcctatct gactttacat cttcccttcg gacactgctg ctgagtcata
2221 acaggatttc ccacctaccc tctggctttc tttctgaagt cagtagtctg aagcacctcg
2281 atttaagttc caatctgcta aaaacaatca acaaatccgc acttgaaact aagaccacca
2341 ccaaattatc tatgttggaa ctacacggaa acccctttga atgcacctgt gacattggag
2401 atttccgaag atggatggat gaacatctga atgtcaaaat tcccagactg gtagatgtca
2461 tttgtgccag tcctggggat caaagaggga agagtattgt gagtctggag ctaacaactt
2521 gtgtttcaga tgtcactgca gtgatattat ttttcttcac gttctttatc accaccatgg
2581 ttatgttggc tgccctggct caccatttgt tttactggga tgtttggttt atatataatg
2641 tgtgtttagc taaggtaaaa ggctacaggt ctctttccac atcccaaact ttctatgatg
2701 cttacatttc ttatgacacc aaagatgcct ctgttactga ctgggtgata aatgagctgc
2761 gctaccacct tgaagagagc cgagacaaaa acgttctcct ttgtctagag gagagggatt
2821 gggacccggg attggccatc atcgacaacc tcatgcagag catcaaccaa agcaagaaaa
2881 cagtatttgt tttaaccaaa aaatatgcaa aaagctggaa ctttaaaaca gctttttact
2941 tggctttgca gaggctaatg gatgagaaca tggatgtgat tatatttatc ctgctggagc
3001 cagtgttaca gcattctcag tatttgaggc tacggcagcg gatctgtaag agctccatcc
3061 tccagtggcc tgacaacccg aaggcagaag gcttgttttg gcaaactctg agaaatgtgg
3121 tcttgactga aaatgattca cggtataaca atatgtatgt cgattccatt aagcaatact
3181 aactgacgtt aagtcatgat ttcgcgccat aataaagatg caaaggaatg acatttctgt
3241 attagttatc tattgctatg taacaaatta tcccaaaact tagtggttta aaacaacaca
3301 tttgctggcc cacagttttt gagggtcagg agtccaggcc cagcataact gggtcctctg
3361 ctcagggtgt ctcagaggct gcaatgtagg tgttcaccag agacataggc atcactgggg
3421 tcacactcat gtggttgttt tctggattca attcctcctg ggctattggc caaaggctat
3481 actcatgtaa gccatgcgag cctctcccac aaggcagctt gcttcatcag agctagcaaa
3541 aaagagaggt tgctagcaag atgaagtcac aatcttttgt aatcgaatca aaaaagtgat
3601 atctcatcac tttggccata ttctatttgt tagaagtaaa ccacaggtcc caccagctcc
3661 atgggagtga ccacctcagt ccagggaaaa cagctgaaga ccaagatggt gagctctgat
3721 tgcttcagtt ggtcatcaac tattttccct tgactgctgt cctgggatgg cctgctatct
3781 tgatgataga ttgtgaatat caggaggcag ggatcactgt ggaccatctt agcagttgac
3841 ctaacacatc ttcttttcaa tatctaagaa cttttgccac tgtgactaat ggtcctaata
3901 ttaagctgtt gtttatattt atcatatatc tatggctaca tggttatatt atgctgtggt
3961 tgcgttcggt tttatttaca gttgctttta caaatatttg ctgtaacatt tgacttctaa
4021 ggtttagatg ccatttaaga actgagatgg atagctttta aagcatcttt tacttcttac
4081 cattttttaa aagtatgcag ctaaattcga agcttttggt ctatattgtt aattgccatt
4141 gctgtaaatc ttaaaatgaa tgaataaaaa tgtttcattt tacaaaaaaa aaaaaaaaa
//