LOCUS AY340963 1684 bp mRNA linear HUM 01-AUG-2004
DEFINITION Homo sapiens interleukin-1 receptor-associated kinase 4 variant
(IRAK4) mRNA, complete cds; alternatively spliced.
ACCESSION AY340963
VERSION AY340963.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1684)
AUTHORS Chuang,T.H. and Ulevitch,R.J.
TITLE Human interleukin-1 receptor associated kinase 4 cDNA sequences
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1684)
AUTHORS Chuang,T.H. and Ulevitch,R.J.
TITLE Direct Submission
JOURNAL Submitted (14-JUL-2003) Immunology, The Scripps Research Institute,
10550 North Torrey Pines Rd., La Jolla, CA 92037, USA
FEATURES Location/Qualifiers
source 1..1684
/db_xref="H-InvDB:HIT000251962"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="12"
/map="12q12"
/tissue_type="spleen"
gene 1..1684
/gene="IRAK4"
CDS 114..1496
/gene="IRAK4"
/note="IRAK4; protein kinase; alternatively spliced"
/codon_start=1
/product="interleukin-1 receptor-associated kinase 4
variant"
/protein_id="AAR02359.1"
/translation="MNKPITPSTYVRCLNVGLIRKLSDFIDPQEGWKKLAVAIKKPSG
DDRYNQFHIRRFEALLQTGKSPTSELLFDWGTTNCTVGDLVDLLIQNEFFAPASLLLP
DAVPKTANTLPSKEAITVQQKQMPFCDKDRTLMTPVQNLEQSYMPPDSSSPENKSLEV
SDTRFHSFSFYELKNVTNNFDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAM
VDITTEELKQQFDQEIKVMAKCQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSC
LDGTPPLSWHMRCKIAQGAANGINFLHENHHIHRDIKSANILLDEAFTAKISDFGLAR
ASEKFAQTVMTSRIVGTTAYMAPEALRGEITPKSDIYSFGVVLLEIITGLPAVDEHRE
PQLLLDIKEEIEDEEKTIEDYIDKKMNDADSTSVEAMYSVASQCLHEKKNKRPDIKKV
QQLLQEMTAS"
BASE COUNT 549 a 310 c 338 g 487 t
ORIGIN
1 cttcctagtt cggctggttc ttctgtcgcc ggcttcagca gcccgcgccc gggcaggggc
61 ctggagcagt atctagcaca aagtagacac tcagtaaata tttggaatag aagatgaaca
121 aacccataac accatcaaca tatgtgcgct gcctcaatgt tggactaatt aggaagctgt
181 cagattttat tgatcctcaa gaaggatgga agaagttagc tgtagctatt aaaaaaccat
241 ctggtgatga tagatacaat cagtttcaca taaggagatt tgaagcatta cttcaaactg
301 gaaaaagtcc cacttctgaa ttactgtttg actggggcac cacaaattgc acagttggtg
361 atcttgtgga tcttttgatc caaaatgaat tttttgctcc tgcgagtctt ttgctcccag
421 atgctgttcc caaaactgct aatacactac cttctaaaga agctataaca gttcagcaaa
481 aacagatgcc tttctgtgac aaagacagga cattgatgac acctgtgcag aatcttgaac
541 aaagctatat gccacctgac tcctcaagtc cagaaaataa aagtttagaa gttagtgata
601 cacgttttca cagtttttca ttttatgaat tgaagaatgt cacaaataac tttgatgaac
661 gacccatttc tgttggtggt aataaaatgg gagagggagg atttggagtt gtatataaag
721 gctacgtaaa taacacaact gtggcagtga agaagcttgc agcaatggtt gacattacta
781 ctgaagaact gaaacagcag tttgatcaag aaataaaagt aatggcaaag tgtcaacatg
841 aaaacttagt agaactactt ggtttctcaa gtgatggaga tgacctctgc ttagtatatg
901 tttacatgcc taatggttca ttgctagaca gactctcttg cttggatggt actccaccac
961 tttcttggca catgagatgc aagattgctc agggtgcagc taatggcatc aattttctac
1021 atgaaaatca tcatattcat agagatatta aaagtgcaaa tatcttactg gatgaagctt
1081 ttactgctaa aatatctgac tttggccttg cacgggcttc tgagaagttt gcccagacag
1141 tcatgactag cagaattgtg ggaacaacag cttatatggc accagaagct ttgcgtggag
1201 aaataacacc caaatctgat atttacagct ttggtgtggt tttactagaa ataataactg
1261 gacttccagc tgtggatgaa caccgtgaac ctcagttatt gctagatatt aaagaagaaa
1321 ttgaagatga agaaaagaca attgaagatt atattgataa aaagatgaat gatgctgatt
1381 ccacttcagt tgaagctatg tactctgttg ctagtcaatg tctgcatgaa aagaaaaata
1441 agagaccaga cattaagaag gttcaacagc tgctgcaaga gatgacagct tcttaaaact
1501 ttattgaaaa agactcttga ctttttatat acacctatct caaccatttt tttaactgat
1561 ttttttccta aatattcttc tttaccttta acaaggcata ggctgttgca ggacagtggt
1621 tattaaagca tgggttgaac ttccaaaata taaaaataga gccaccatat caacacttag
1681 ccct
//