LOCUS AY337518 3528 bp mRNA linear HUM 06-OCT-2004
DEFINITION Homo sapiens HECT E3 ubiquitin ligase (HERC5) mRNA, complete cds.
ACCESSION AY337518
VERSION AY337518.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3528)
AUTHORS Kroismayr,R., Baranyi,U., Stehlik,C., Dorfleutner,A., Binder,B.R.
and Lipp,J.
TITLE HERC5, a HECT E3 ubiquitin ligase tightly regulated in LPS
activated endothelial cells
JOURNAL J. Cell. Sci. 117 (PT 20), 4749-4756 (2004)
PUBMED 15331633
REFERENCE 2 (bases 1 to 3528)
AUTHORS Kroismayr,R., Baranyi,U., Stehlik,C., Dorfleutner,A., Lipp,J. and
Binder,B.R.
TITLE Direct Submission
JOURNAL Submitted (08-JUL-2003) Vascular Biology and Thrombosis Research,
University Vienna, Brunnerstrasse, Vienna 1230, Austria
FEATURES Location/Qualifiers
source 1..3528
/db_xref="H-InvDB:HIT000251932"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..3528
/gene="HERC5"
CDS 154..3228
/gene="HERC5"
/note="ubiquitin ligase"
/codon_start=1
/product="HECT E3 ubiquitin ligase"
/protein_id="AAR00320.1"
/translation="MERRSRRKSRRNGRSTAGKAAATQPAKSPGAQLWLFPSAAGLHR
ALLRRVEVTRQLCCSPGRLAVLERGGAGVQVHQLLAGSGGARTPKCIKLGKNMKIHSV
DQGAEHMLILSSDGKPFEYDNYSMKHLRFESILQEKKIIQITCGDYHSLALSKGGELF
AWGQNLHGQLGVGRKFPSTTTPQIVEHLAGVPLAQISAGEAHSTALSMSGNIYSWGKN
ECGQLGLGHTESKDDPSLIEGLDNQKVEFVACGGSHSALLTQDGLLFTFGAGKHGQLG
HNSTQNELRPCLVAELVGYRVTQIACGRWHTLAYVSDLGKVFSFGSGKDGQLGNGGTR
DQLMPLPVKVSSSEELKLESHTSEKELIMIAGGNQSILLWIKKENSYVNLKRTIPTLN
EGTVKRWIADVETKRWQSTKREIQEISSSPACLTGSFLRKRRTTEMMPVYLDLNKARN
IFKELTQKDWITNMITTCLKDNLLKRLPFHSPPQEALEIFFLLPECPVMHISNNWESL
VVPFTKVVCKMSDQSSLVLEEYWATLQESTFSKLVQMFKTAVICQLDYWDESAEENGN
VQALLEMLKKLHRVNQVKCQLPESIFQVDELLHRLNFFVEVCRRYLWKMTVDASENVQ
CCVIFSHFPFIFNNLSKIKLLHTDTLLKIESKKHKAYLRSAAIEEERESEFALRPTFD
LTVRRNHLIEDVLNQLSQFENEDLRKELWVSFSGEIGYDLGGVKKEFFYCLFAEMIQP
EYGMFMYPEGASCMWFPVKPKFEKKRYFFFGVLCGLSLFNCNVANLPFPLALFKKLLD
QMPSLEDLKELSPDLGKNLQTLLDDEGDNFEEVFYIHFNVHWDRNDTNLIPNGSSITV
NQTNKRDYVSKYINYIFNDSVKAVYEEFRRGFYKMCDEDIIKLFHPEELKDVIVGNTD
YDWKTFEKNARYEPGYNSSHPTIVMFWKAFHKLTLEEKKKFLVFLTGTDRLQMKDLNN
MKITFCCPESWNERDPIRALTCFSVLFLPKYSTMETVEEALQEAINNNRGFG"
BASE COUNT 1044 a 720 c 832 g 932 t
ORIGIN
1 tcagtagctg aggctgcggt tccccgacgc cacgcagctg cgcgcagctg gttcccgctc
61 tgcagcgcaa cgcctgaggc agtgggcgcg ctcagtcccg ggaccaggcg ttctctcctc
121 tcgcctctgg gcctgggacc ccgcaaagcg gcgatggagc ggaggtcgcg gaggaagtcg
181 cggcgcaacg ggcgctcgac cgcgggcaag gccgccgcga cccagcccgc gaagtctccg
241 ggcgcacagc tctggctctt tcccagcgcc gcgggcctcc accgcgcgct gctccggagg
301 gtggaggtga cgcgccaact ctgctgctcg ccggggcgcc tcgcggtctt ggaacgcggc
361 ggggcgggcg tccaggttca ccagctgctc gccgggagcg gcggcgcccg gacgccgaaa
421 tgcattaaat taggaaaaaa catgaagata cattccgtgg accaaggagc agagcacatg
481 ctgattctct catcagatgg aaaaccattt gagtatgaca actatagcat gaaacatcta
541 aggtttgaaa gcattttaca agaaaaaaaa ataattcaga tcacatgtgg agattaccat
601 tctcttgcac tctcaaaagg tggtgagctt tttgcctggg gacagaacct gcatgggcag
661 cttggagttg gaaggaaatt tccctcaacc accacaccac agattgtgga gcacctcgca
721 ggagtaccct tggctcagat ttctgccgga gaagcccaca gcacggcctt atccatgtct
781 ggcaacattt attcatgggg aaaaaatgaa tgtggacaac taggcctggg ccacactgag
841 agtaaagatg atccatccct tattgaagga ctagacaatc agaaagttga atttgtcgct
901 tgtggtggct ctcacagtgc cctactcaca caggatgggc tgctgtttac tttcggtgct
961 ggaaaacatg ggcaacttgg tcataattca acacagaatg agctaagacc ctgtttggtg
1021 gctgagcttg ttgggtatag agtgactcag atagcatgtg gaaggtggca cacacttgcc
1081 tatgtttctg atttgggaaa ggtcttttcc tttggttctg gaaaagatgg acaactggga
1141 aatggtggaa cacgtgacca gctgatgccg cttccagtga aagtatcatc aagtgaagaa
1201 ctcaaacttg aaagccatac ctcagaaaag gagttaataa tgattgctgg agggaatcaa
1261 agcattttgc tctggataaa gaaagagaat tcatatgtta atctgaagag gacaattcct
1321 actctgaatg aagggactgt aaagagatgg attgctgatg tggagactaa acggtggcag
1381 agcacaaaaa gggaaatcca agagatatct tcatctcctg cttgtctaac tggaagtttt
1441 ttaaggaaaa gaagaactac agaaatgatg cctgtttatt tggacttaaa taaagcaaga
1501 aacatcttca aggagttaac ccaaaaggac tggattacta acatgataac cacctgcctc
1561 aaagataatc tgctcaaaag acttccattt cattctccac cccaagaagc tttagaaatt
1621 ttcttccttc tcccagaatg tcctgtgatg catatttcca acaactggga gagccttgtg
1681 gttccattta caaaggttgt ttgtaaaatg agtgaccagt cttcactggt tctggaagag
1741 tattgggcaa ctctgcaaga atccactttc agcaaactgg tccagatgtt taaaacagcc
1801 gtcatatgcc agttggatta ctgggatgaa agtgctgagg agaatggtaa tgttcaagct
1861 ctcctagaaa tgttgaagaa gctgcacagg gtaaaccagg tgaaatgtca actacctgaa
1921 agtattttcc aagtagacga actcttgcac cgtctcaatt tttttgtaga agtatgcaga
1981 aggtacttgt ggaaaatgac tgtggacgct tcagaaaatg tacaatgctg cgtcatattc
2041 agtcactttc catttatctt taataatctg tcgaaaatta aactactaca tacagacaca
2101 cttttaaaaa tagagagtaa aaaacataaa gcttatctta ggtcggcagc aattgaggaa
2161 gaaagagagt ctgaattcgc tttgaggccc acgtttgatc taacagtcag aaggaatcac
2221 ttgattgagg atgttttgaa tcagctaagt caatttgaga atgaagacct gaggaaagag
2281 ttatgggttt catttagtgg agaaattggg tatgacctcg gaggagtcaa gaaagagttc
2341 ttctactgtc tgtttgcaga gatgatccag ccggaatatg ggatgttcat gtatcctgaa
2401 ggggcttcct gcatgtggtt tcctgtcaag cctaaatttg agaagaaaag atacttcttt
2461 tttggggttc tatgtggact ttccctgttc aattgcaatg ttgccaacct ccctttccca
2521 ctggcactgt ttaagaaact tttggaccaa atgccatcat tggaagactt gaaagaactc
2581 agtcctgatt tgggaaagaa tttgcaaaca cttctggatg atgaaggtga taactttgag
2641 gaagtatttt acatccattt taatgtgcac tgggacagaa acgacacaaa cttaattcct
2701 aatggaagta gcataactgt caaccagact aacaagagag actatgtttc taagtatatc
2761 aattacattt tcaacgactc tgtaaaggcg gtttatgaag aatttcggag aggattttat
2821 aaaatgtgcg acgaagacat tatcaaatta ttccaccccg aagaactgaa ggatgtgatt
2881 gttggaaata cagattatga ttggaaaaca tttgaaaaga atgcacgtta tgaaccagga
2941 tataacagtt cacatcccac catagtgatg ttttggaagg ctttccacaa attgactctg
3001 gaagaaaaga aaaaattcct tgtatttctt acaggaactg acagactaca aatgaaagat
3061 ttaaataata tgaaaataac attttgctgt cctgaaagtt ggaatgaaag agaccctata
3121 agagcactga catgtttcag tgtcctcttc ctccctaaat attctacaat ggaaacagtt
3181 gaagaagcgc ttcaagaagc catcaacaac aacagaggat ttggctgacc agcttgcttg
3241 tccaacagcc ttattttgtt gttgttatcg ttgttgttgt tgttgttgtt gttgtttctc
3301 tactttgttt tgttttagct tttagcagcc tgaagccatg gtttttcatt tctgtctcta
3361 gtgataagca ggaaagaggg atgaagaaga gggtttactg gccggttaga acccgtgact
3421 gtattctctc ccttggatac ccctatgcct acatcatatt ccttacctct tttgggaaat
3481 atttttcaaa aataaaataa ccgaaaatta aaaaaaaaaa aaaaaaaa
//