LOCUS AY333756 2046 bp mRNA linear HUM 07-OCT-2004
DEFINITION Homo sapiens ATP-binding cassette sub-family G (WHITE) member 2
(ABCG2) mRNA, complete cds.
ACCESSION AY333756
VERSION AY333756.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2046)
AUTHORS Sudarikov,A., Makarik,T. and Andreeff,M.
TITLE Cell line K562 resistant to Hoechst 33342
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 2046)
AUTHORS Sudarikov,A., Makarik,T. and Andreeff,M.
TITLE Direct Submission
JOURNAL Submitted (30-JUN-2003) Laboratory for Molecular Hematology,
Hematology Research Center, Novozykovsky 4a, Moscow 125167, Russia
FEATURES Location/Qualifiers
source 1..2046
/db_xref="H-InvDB:HIT000251888"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="ATCC:CCL-243"
/db_xref="taxon:9606"
/chromosome="4"
/map="4q22"
/cell_line="K562; ATCC CCL-243"
gene 1..2046
/gene="ABCG2"
CDS 10..1977
/gene="ABCG2"
/note="ABC transporter; breast cancer resistance protein;
mitoxantrone resistance protein; placenta specific MDR
protein"
/codon_start=1
/product="ATP-binding cassette sub-family G (WHITE) member
2"
/protein_id="AAQ92942.1"
/translation="MSSSNVEVFIPVSQGNTNGFPATASNDLKAFTEGAVLSFHNICY
RVKLKSGFLPCRKPVEKEILSNINGIMKPGLNAILGPTGGGKSSLLDVLAARKDPSGL
SGDVLINGAPRPANFKCNSGYVVQDDVVMGTLTVRENLQFSAALRLATTMTNHEKNER
INRVIQELGLDKVADSKVGTQFIRGVSGGERKRTSIGMELITDPSILFLDEPTTGLDS
STANAVLLLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGRLMFHGPAQEALGY
FESAGYHCEAYNNPADFFLDIINGDSTAVALNREEDFKATEIIEPSKQDKPLIEKLAE
IYVNSSFYKETKAELHQLSGGEKKKKITVFKEISYTTSFCHQLRWVSKRSFKNLLGNP
QASIAQIIVTVVLGLVIGAIYFGLKNDSTGIQNRAGVLFFLTTNQCFSSVSAVELFVV
EKKLFIHEYISGYYRVSSYFLGKLLSDLLPMRMLPSIIFTCIVYFMLGLKPKADAFFV
MMFTLMMVAYSASSMALAIAAGQSVVSVATLLMTICFVFMMIFSGLLVNLTTIASWLS
WLQYFSIPRYGFTALQHNEFLGQNFCPGLNATGNNPCNYATCTGEEYLVKQGIDLSPW
GLWKNHVALACMIVIFLTIAYLKLLFLKKYS"
BASE COUNT 581 a 432 c 438 g 595 t
ORIGIN
1 actctccaga tgtcttccag taatgtcgaa gtttttatcc cagtgtcaca aggaaacacc
61 aatggcttcc ccgcgacagc ttccaatgac ctgaaggcat ttactgaagg agctgtgtta
121 agttttcata acatctgcta tcgagtaaaa ctgaagagtg gctttctacc ttgtcgaaaa
181 ccagttgaga aagaaatatt atcgaatatc aatgggatca tgaaacctgg tctcaacgcc
241 atcctgggac ccacaggtgg aggcaaatct tcgttattag atgtcttagc tgcaaggaaa
301 gatccaagtg gattatctgg agatgttctg ataaatggag caccgcgacc tgccaatttc
361 aaatgtaatt caggttacgt ggtacaagat gatgttgtga tgggcactct gacggtgaga
421 gaaaacttac agttctcagc agctcttcgg cttgcaacaa ctatgacgaa tcatgaaaaa
481 aacgaacgga ttaacagggt cattcaagag ttaggtctgg ataaagtggc agactccaag
541 gttggaactc agtttatccg tggtgtgtct ggaggagaaa gaaaaaggac tagtatagga
601 atggagctta tcactgatcc ttccatcttg ttcttggatg agcctacaac tggcttagac
661 tcaagcacag caaatgctgt ccttttgctc ctgaaaagga tgtctaagca gggacgaaca
721 atcatcttct ccattcatca gcctcgatat tccatcttca agttgtttga tagcctcacc
781 ttattggcct caggaagact tatgttccac gggcctgctc aggaggcctt gggatacttt
841 gaatcagctg gttatcactg tgaggcctat aataaccctg cagacttctt cttggacatc
901 attaatggag attccactgc tgtggcatta aacagagaag aagactttaa agccacagag
961 atcatagagc cttccaagca ggataagcca ctcatagaaa aattagcgga gatttatgtc
1021 aactcctcct tctacaaaga gacaaaagct gaattacatc aactttccgg gggtgagaag
1081 aagaagaaga tcacagtctt caaggagatc agctacacca cctccttctg tcatcaactc
1141 agatgggttt ccaagcgttc attcaaaaac ttgctgggta atccccaggc ctctatagct
1201 cagatcattg tcacagtcgt actgggactg gttataggtg ccatttactt tgggctaaaa
1261 aatgattcta ctggaatcca gaacagagct ggggttctct tcttcctgac gaccaaccag
1321 tgtttcagca gtgtttcagc cgtggaactc tttgtggtag agaagaagct cttcatacat
1381 gaatacatca gcggatacta cagagtgtca tcttatttcc ttggaaaact gttatctgat
1441 ttattaccca tgaggatgtt accaagtatt atatttacct gtatagtgta cttcatgtta
1501 ggattgaagc caaaggcaga tgccttcttc gttatgatgt ttacccttat gatggtggct
1561 tattcagcca gttccatggc actggccata gcagcaggtc agagtgtggt ttctgtagca
1621 acacttctca tgaccatctg ttttgtgttt atgatgattt tttcaggtct gttggtcaat
1681 ctcacaacca ttgcatcttg gctgtcatgg cttcagtact tcagcattcc acgatatgga
1741 tttacggctt tgcagcataa tgaatttttg ggacaaaact tctgcccagg actcaatgca
1801 acaggaaaca atccttgtaa ctatgcaaca tgtactggcg aagaatattt ggtaaagcag
1861 ggcatcgatc tctcaccctg gggcttgtgg aagaatcacg tggccttggc ttgtatgatt
1921 gttattttcc tcacaattgc ctacctgaaa ttgttatttc ttaaaaaata ttcttaaatt
1981 tccccttaat tcagtatgat ttatcctcac ataaaaaaga agcactttga ttgaagtatt
2041 caatca
//