LOCUS AY332222 2021 bp mRNA linear HUM 26-JUL-2003
DEFINITION Homo sapiens impedes mitogenic signal propagation mRNA, complete
cds.
ACCESSION AY332222
VERSION AY332222.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2021)
AUTHORS Matheny,S.A. and White,M.A.
TITLE IMP (Impedes Mitogenic Signal Propagation) Restricts MEK Activation
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 2021)
AUTHORS Matheny,S.A. and White,M.A.
TITLE Direct Submission
JOURNAL Submitted (27-JUN-2003) Cell Biology, UTSWMC, 5323 Harry Hines
Blvd., Dallas, TX 75390-9039, USA
FEATURES Location/Qualifiers
source 1..2021
/db_xref="H-InvDB:HIT000251874"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="12"
/map="12q24.1"
CDS 140..1918
/note="IMP; E3 ubiquitin ligase; similar to sequence found
in NM_006768"
/codon_start=1
/product="impedes mitogenic signal propagation"
/protein_id="AAP93638.1"
/translation="MSVSLVVIRLELAEHSPVPAGFGFSAAAGEMSDEEIKKTTLASA
VACLEGKSPGEKVAIIHQHLGRREMTDVIIETMKSNPDELKTTVEERKSSEASPTAQR
SKDHSKECINAAPDSPSKQLPDQISFFSGNPSVEIVHGIMHLYKTNKMTSLKEDVRRS
AMLCILTVPAAMTSHDLMKFVAPFNDVIEQMKIIRDSTPNQYMVLIKFRAQADADSFY
MTCNGRQFNSIEDDVCQLVYVERAEVLKSEDGASLPVMDLTELPKCTVCLERMDESVN
GILTTLCNHSFHSQCLQRWDDTTCPVCRYCQTPEPVEENKCFECGVQENLWICLICGH
IGCGRYVSRHAYKHFEETQHTYAMQLTNHRVWDYAGDNYVHRLVASKTDGKIVQYECE
GDTCQEEKIDALQLEYSYLLTSQLESQRIYWENKIVRIEKDTAEEINNMKTKFKETIE
KCDNLEHKLNDLLKEKQSVERKCTQLNTKVAKLTNELKEEQEMNKCLRANQVLLQNKL
KEEERVLKETCDQKDLQITEIQEQLRDVMFYLETQQKINHLPAETRQEIQEGQINIAM
ASASSPASSGGSGKLPSRKGRSKRGK"
BASE COUNT 591 a 477 c 528 g 425 t
ORIGIN
1 gttcgaggag ctgctgctgc tgaggcggcg gcaactgcat tgaggtggtg gcggcgctgc
61 cggccccggc cgctcgctct cggctcgcct tccagcctcg cctgagcccg ccgggcccgc
121 gccggccagc gcctgcccta tgagtgtgtc actggttgtt atccgattgg agctcgcgga
181 acactcgcct gtccccgccg gcttcggctt cagcgccgcg gccggggaaa tgtctgatga
241 ggagataaaa aagacgacac tagcctcagc tgtagcctgt ttagaaggca agtcaccagg
301 agagaaagta gcgattatcc atcagcatct cggccgtcga gaaatgacag atgtgatcat
361 tgagaccatg aagtccaacc cagatgaact aaaaactaca gtggaagaaa ggaagtcttc
421 agaagcctcc cccactgcgc aaagaagtaa agatcacagt aaggaatgca taaacgctgc
481 cccagattct ccgtccaaac agcttccaga ccagatttca ttcttcagtg gaaatccatc
541 agttgaaata gttcatggta ttatgcacct atataagaca aataagatga cctccttaaa
601 agaagatgtg cggcgcagtg ccatgctgtg tattctcaca gtccctgctg caatgaccag
661 tcatgacctt atgaagtttg ttgccccatt taacgacgta attgaacaaa tgaaaattat
721 cagagactct actcccaacc aatatatggt gctgataaag tttcgtgcac aggctgatgc
781 ggatagtttt tatatgacat gcaatggccg ccagttcaac tcaatagaag atgacgtttg
841 ccagctagtg tatgtggaaa gagctgaagt gctcaaatct gaagatggcg ccagcctccc
901 agtgatggac ctgactgaac tccccaagtg cacggtgtgt ctggagcgca tggacgagtc
961 tgtgaatggc atcctcacaa cgttatgtaa ccacagcttc cacagccagt gtctacagcg
1021 ctgggacgat accacgtgtc ctgtttgccg gtactgtcaa acgcccgagc cagtagaaga
1081 aaataagtgt tttgagtgtg gtgttcagga aaatctttgg atttgtttaa tatgcggcca
1141 cataggatgt ggacggtatg tcagtcgaca tgcttataag cactttgagg aaacgcagca
1201 cacgtatgcc atgcagctta ccaaccatcg agtctgggac tatgctggag ataactatgt
1261 tcatcgactg gttgcaagta aaacagatgg aaaaatagta cagtatgaat gtgaggggga
1321 tacttgccag gaagagaaaa tagatgcctt acagttagag tattcatatt tactaacaag
1381 ccagctggaa tctcagcgaa tctactggga aaacaagata gttcggatag agaaggacac
1441 agcagaggaa attaacaaca tgaagaccaa gtttaaagaa acaattgaga agtgtgataa
1501 tctagagcac aaactaaatg atctcctaaa agaaaagcag tctgtggaaa gaaagtgcac
1561 tcagctaaac acaaaagtgg ccaaactcac caacgagctc aaagaggagc aggaaatgaa
1621 caagtgtttg cgagccaacc aagtcctcct gcagaacaag ctaaaagagg aggagagggt
1681 gctgaaggag acctgtgacc aaaaagatct gcagatcacc gagatccagg agcagctgcg
1741 tgacgtcatg ttctacctgg agacacagca gaagatcaac catctgcctg ccgagacccg
1801 gcaggaaatc caggagggac agatcaacat cgccatggcc tcggcctcga gccctgcctc
1861 ttcggggggc agtgggaagt tgccctccag gaagggccgc agcaagaggg gcaagtgacc
1921 ttcagagcaa cagacatccc tgagactgtt ctccctgaca ctgtgagagt gtgctgggac
1981 cttcagctaa atgtgagggt gggccctaat aagtacaagt g
//