LOCUS AY327122 5293 bp mRNA linear HUM 01-JUL-2006
DEFINITION Homo sapiens COMPase precursor, mRNA, complete cds.
ACCESSION AY327122
VERSION AY327122.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5293)
AUTHORS Liu,C., Prazak,L. and DiCesare,P.E.
TITLE Human COMPase
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 5293)
AUTHORS Liu,C., Prazak,L. and DiCesare,P.E.
TITLE Direct Submission
JOURNAL Submitted (20-JUN-2003) Orthopaedic Surgery, New York University,
301 East 17th Street, New York, NY 10003, USA
FEATURES Location/Qualifiers
source 1..5293
/db_xref="H-InvDB:HIT000386038"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="15"
CDS 11..5071
/note="metalloproteinase; ADAMTS; COMP-binding protein"
/codon_start=1
/product="COMPase precursor"
/protein_id="AAQ94616.1"
/translation="MPGGPSPRSPAPLLRPLLLLLCALAPGAPGPAPGRATEGRAALD
IVHPVRVDAGGSFLSYELWPRALRKRDVSVRRDAPAFYELQYRGRELRFNLTANQHLL
APGFVSETRRRGGLGRAHIRAHTPACHLLGEVQDPELEGGLAAISACDGLKGVFQLSN
EDYFIEPLDSAPARPGHAQPHVVYKRQAPERLAQRGDSSAPSTCGVQVYPELESRRER
WEQRQQWRRPRLRRLHQRSVSKEKWVETLVVADAKMVEYHGQPQVESYVLTIMNMVAG
LFHDPSIGNPIHITIVRLVLLEDEEEDLKITHHADNTLKSFCKWQKSINMKGDAHPLH
HDTAILLTRKDLCAAMNRPCETLGLSHVAGMCQPHRSCSINEDTGLPLAFTVAHELGH
SFGIQHDGSGNDCEPVGKRPFIMSPQLLYDAAPLTWSRCSRQYITRFLDRGWGLCLDD
PPAKDIIDFPSVPPGVLYDVSHQCRLQYGAYSAFCEDMDNVCHTLWCSVGTTCHSKLD
AAVDGTRCGENKWCLSGECVPVGFRPEAVDGGWSGWSAWSICSRSCGMGVQSAERQCT
QPTPKYKGRYCVGERKRFRLCNLQACPAGXPSFRHVQCSHFDAMLYKGQLHTWVPVVN
DVNPCELHCRPANEYFAEKLRDAVVDGTPCYQVRASRDLCINGICKNVGCDFEIDSGA
MEDRCGVCHGNGSTCHTVSGTFEEAEGLGYVDVGLIPAGAREIRIQEVAEAANFLALR
SEDPEKYFLNGGWTIQWNGDYQVAGTTFTYARRGNWENLTSPGPTKEPVWIQLLFQES
NPGVHYEYTIHREAGGHDEVPPPVFSWHYGPWTKCTVTCGRGVQRQNVYCLERQAGPV
DEEHCDPLGRPDDQQRKCSEQPCPARWWAGEWQLCSSSCGPGGLSRRAVLCIRSVGLD
EQSALEPPACEHLPRPPTETPCNRHVPCPATWAVGNWSQCSVTCGEGTQRRNVLCTND
TGVPCDEAQQPASEVTCSLPLCRWPLGTLGPEGSGSGSSSHELFNEADFIPHHLAPRP
SPASSPKPGTMGNAIEEEAPELDLPGPVFVDDFYYDYNFINFHEDLSYGPSEEPDLDL
AGTGDRTPPPHSRPAAPSTGSPVPATEPPAAKEEGVLGPWSPSPWPSQAGRSPPPPSE
QTPGNPLINFLPEEDTPIGAPDLGLPSLSWPRVSTDGLQTPATPESQNDFPVGKDSQS
QLPPPWRDRTNEVFKDDEEPKGRGAPHLPPRPSSTLPPLSPVGSTHSSPSPDVAELWT
GGTVAWEPALEGGLGPVDSELWPTVGVASLLPPPIAPLPEMKVRDSSLEPGTPSFPAP
GPGSWDLQTVAVWGTFLPTTLTGLGHMPEPALNPGPKGQPESLTPEVPLSSRLLSTPA
WDSPANSHRVPETQPLAPSLAEAGPPADPLVVRNASWQAGNWSECSTTCGLGAVWRPV
RCSSGRDEDCAPAGRPQPARRCHLRPCATWHSGNWSKCSRSCDGGSSVRDVQCVDTRD
LRPLRPFHCQPGPAKPHAHRPCGAQPCLSWYTSSWRECSEACGGGEQQRLVTCPEPGL
CEEALRPNTTRPCNTHPCTQWVVGPWGQCSAPCGGGVQRRLVKCVNTQTGLPEEDSDQ
CGHEAWPESSRPCGTEDCEPVEPPRCERDRLSFGFCETLRLLGRCQLPTIRTQCCRSC
SPPSHGAPSRGHQRVARR"
BASE COUNT 942 a 1817 c 1630 g 903 t
ORIGIN
1 ggttcctgcc atgcccggcg gccccagtcc ccgcagcccc gcgcctttgc tgcgccccct
61 cctcctgctc ctctgcgctc tggctcccgg cgcccccgga cccgcaccag gacgtgcaac
121 cgagggccgg gcggcactgg acatcgtgca cccggttcga gtcgacgcgg ggggctcctt
181 cctgtcctac gagctgtggc cccgcgcact gcgcaagcgg gatgtatctg tgcgccgaga
241 cgcgcccgcc ttctacgagc tacaataccg cgggcgcgag ctgcgcttca acctgaccgc
301 caatcagcac ctgctggcgc ccggctttgt gagcgagacg cggcggcgcg gcggcctggg
361 ccgcgcgcac atccgggccc acaccccggc ctgccacctg cttggcgagg tgcaggaccc
421 tgagctcgag ggtggcctgg cggccatcag cgcctgcgac ggcctgaaag gtgtgttcca
481 actctccaac gaggactact tcattgagcc cctggacagt gccccggccc ggcctggcca
541 cgcccagccc catgtggtgt acaagcgtca ggccccggag aggctggcac agcggggtga
601 ttccagtgct ccaagcacct gtggagtgca agtgtaccca gagctggagt ctcgacggga
661 gcgttgggag cagcggcagc agtggcggcg gccacggctg aggcgtctac accagcggtc
721 ggtcagcaaa gagaagtggg tggagaccct ggtagtagct gatgccaaaa tggtggagta
781 ccacggacag ccgcaggttg agagctatgt gctgaccatc atgaacatgg tggctggcct
841 gtttcatgac cccagcattg ggaaccccat ccacatcacc attgtgcgcc tggtcctgct
901 ggaagatgag gaggaggacc taaagatcac gcaccatgca gacaacaccc tgaagagctt
961 ctgcaagtgg cagaaaagca tcaacatgaa gggggatgcc catcccctgc accatgacac
1021 tgccatcctg ctcaccagaa aggacctgtg tgcagccatg aaccggccct gtgagaccct
1081 gggactgtcc catgtggcgg gcatgtgcca gccgcaccgc agctgcagca tcaacgagga
1141 cacgggcctg ccgctggcct tcactgtagc ccacgagctc gggcacagtt ttggcattca
1201 gcatgacgga agcggcaatg actgtgagcc cgttgggaaa cgacctttca tcatgtctcc
1261 acagctcctg tacgacgccg ctcccctcac ctggtcccgc tgcagccgcc agtatatcac
1321 caggttcctt gaccgtgggt ggggcctgtg cctggacgac cctcctgcca aggacattat
1381 cgacttcccc tcggtgccac ctggcgtcct ctatgatgta agccaccagt gccgcctcca
1441 gtacggggcc tactctgcct tctgcgagga catggataat gtctgccaca cactctggtg
1501 ctctgtgggg accacctgtc actccaagct ggatgcagcc gtggacggca cccggtgtgg
1561 ggagaataag tggtgtctca gtggggagtg cgtacccgtg ggcttccggc ccgaggccgt
1621 ggatggtggc tggtctggct ggagcgcctg gtccatctgc tcacggagct gtggcatggg
1681 cgtacagagc gccgagcggc agtgcacgca gcctacgccc aaatacaaag gcagatactg
1741 tgtgggtgag cgcaagcgct tccgcctctg caacctgcag gcctgccctg ctggccnccc
1801 ctccttccgc cacgtccagt gcagccactt tgacgctatg ctctacaagg gccagctgca
1861 cacatgggtg cccgtggtca atgacgtgaa cccctgcgag ctgcactgcc ggcccgcgaa
1921 tgagtacttt gccgagaagc tgcgggacgc cgtggtcgat ggcaccccct gctaccaggt
1981 ccgagccagc cgggacctct gcatcaacgg catctgtaag aacgtgggct gtgacttcga
2041 gattgactcc ggtgctatgg aggaccgctg tggtgtgtgc cacggcaacg gctccacctg
2101 ccacaccgtg agcgggacct tcgaggaggc cgagggcctg gggtatgtgg atgtggggct
2161 gatcccagcc ggcgcacgcg agatccgcat ccaagaggtt gccgaggctg ccaacttcct
2221 ggcactgcgg agtgaggacc cggagaagta cttcctcaat ggtggctgga ccatccagtg
2281 gaacggggac taccaggtgg cagggaccac cttcacatac gcacgcaggg gcaactggga
2341 gaacctcacg tccccgggtc ccaccaagga gcctgtctgg atccagctgc tgttccagga
2401 gagcaaccct ggggtgcact acgagtacac catccacagg gaggcaggtg gccacgacga
2461 ggtcccgccg cccgtgttct cctggcatta tgggccctgg accaagtgca cagtcacctg
2521 cggcagaggt gtgcagaggc agaatgtgta ctgcttggag cggcaggcag ggcccgtgga
2581 cgaggagcac tgtgaccccc tgggccggcc tgatgaccaa cagaggaagt gcagcgagca
2641 gccctgccct gccaggtggt gggcaggtga gtggcagctg tgctccagct cctgcgggcc
2701 tgggggcctc tcccgccggg ccgtgctctg catccgcagc gtggggctgg atgagcagag
2761 cgccctggag ccacccgcct gtgaacacct tccccggccc cctactgaaa ccccttgcaa
2821 ccgccatgta ccctgtccgg ccacctgggc tgtggggaac tggtctcagt gctcagtgac
2881 atgtggggag ggcactcagc gccgaaatgt cctctgcacc aatgacaccg gtgtcccctg
2941 tgacgaggcc cagcagccag ccagcgaagt cacctgctct ctgccactct gtcggtggcc
3001 cctgggcaca ctgggccctg aaggctcagg cagcggctcc tccagccacg agctcttcaa
3061 cgaggctgac ttcatcccgc accacctggc cccacgccct tcacccgcct catcacccaa
3121 gccaggcacc atgggcaacg ccattgagga ggaggctcca gagctggacc tgccggggcc
3181 cgtgtttgtg gacgacttct actacgacta caatttcatc aatttccacg aggatctgtc
3241 ctacgggccc tctgaggagc ccgatctaga cctggcgggg acaggggacc ggacaccccc
3301 accacacagc cgtcctgctg cgccctccac gggtagccct gtgcctgcca cagagcctcc
3361 tgcagccaag gaggaggggg tactgggacc ttggtccccg agcccttggc ctagccaggc
3421 cggccgctcc ccacccccac cctcagagca gacccctggg aaccctttga tcaatttcct
3481 gcctgaggaa gacaccccca taggggcccc agatcttggg ctccccagcc tgtcctggcc
3541 cagggtttcc actgatggcc tgcagacacc tgccacccct gagagccaaa atgatttccc
3601 agttggcaag gacagccaga gccagctgcc ccctccatgg cgggacagga ccaatgaggt
3661 tttcaaggat gatgaggaac ccaagggccg cggagcaccc cacctgcccc cgagacccag
3721 ctccacgctg ccccctttgt cccctgttgg cagcacccac tcctctccta gtcctgacgt
3781 ggcggagctg tggacaggag gcacagtggc ctgggagcca gctctggagg gtggcctggg
3841 gcctgtggac agtgaactgt ggcccactgt tggggtggct tctctccttc ctcctcccat
3901 agcccctctg ccagagatga aggtcaggga cagttccctg gagccgggga ctccctcctt
3961 cccagcccca ggaccaggct catgggacct gcagactgtg gcagtgtggg ggaccttcct
4021 ccccacaacc ctgactggcc tcgggcacat gcctgagcct gccctgaacc caggacccaa
4081 gggtcagcct gagtccctca cccctgaggt gcccctgagc tctaggctgc tgtccacacc
4141 agcttgggac agccccgcca acagccacag agtccctgag acccagccgc tggctcccag
4201 cctggctgaa gcggggcccc ccgcggaccc gttggttgtc aggaacgcca gctggcaagc
4261 gggaaactgg agcgagtgct ctaccacctg tggcctgggt gcggtctgga ggccggtgcg
4321 ctgtagctcc ggccgggatg aggactgcgc ccccgctggc cggccccagc ctgcccgccg
4381 ctgccaccta cggccctgtg ccacctggca ctcaggcaac tggagtaagt gctcccgcag
4441 ctgcgacgga ggttcctcag tgcgggacgt gcagtgtgtg gacacacggg acctccggcc
4501 actgcggccc ttccattgtc agcccgggcc tgccaagccg catgcgcacc ggccctgcgg
4561 ggcccagccc tgcctcagct ggtacacatc ttcctggagg gagtgctccg aggcctgtgg
4621 cggtggtgag cagcagcgtc tagtgacctg cccggagcca ggcctctgcg aggaggcgct
4681 gagacccaac accacccggc cctgcaacac ccacccctgc acgcagtggg tggtggggcc
4741 ctggggccag tgctcagccc cctgtggtgg tggtgtccag cggcgcctgg tcaagtgtgt
4801 caacacccag acagggctgc ccgaggaaga cagtgaccag tgtggccacg aggcctggcc
4861 tgagagctcc cggccgtgtg gcaccgagga ttgtgagccc gtcgagcctc cccgctgtga
4921 gcgggaccgc ctgtccttcg ggttctgcga gacgctgcgc ctactgggcc gctgccagct
4981 gcccaccatc cgcacccagt gctgccgctc gtgctctccg cccagccacg gcgccccctc
5041 ccgaggccat cagcgggttg cccgccgctg actgtgccag gatgcacaga ccgaccgaca
5101 gacctcagtg cccaccacgg gctgtggcgg agctcccgcc ccctgcgccc taatggtgct
5161 aaccccctct cactacccag cagcaggctg gggacctcct ccccctcaaa aaaggtattt
5221 ttttattcta acagtttgtg taacatttat tatgatttta cataaatgag catctaccaa
5281 aaaaaaaaaa aaa
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