LOCUS AY324607 6754 bp DNA linear HUM 24-JUN-2003
DEFINITION Homo sapiens angiotensin receptor 2 (AGTR2) gene, complete cds.
ACCESSION AY324607
VERSION AY324607.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6754)
AUTHORS Rieder,M.J., da Ponte,S.H., Kuldanek,S.A., Rajkumar,N., Smith,J.D.,
Toth,E.J. and Nickerson,D.A.
TITLE Direct Submission
JOURNAL Submitted (17-JUN-2003) Genome Sciences, University of Washington,
1705 NE Pacific, Seattle, WA 98195, USA
FEATURES Location/Qualifiers
source 1..6754
/db_xref="H-InvDB:HIT000386037"
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
variation 237
/frequency="0.05"
/replace="a"
repeat_region 601..757
/rpt_family="MIR"
/rpt_type=dispersed
variation 622
/frequency="0.02"
/replace="t"
repeat_region 764..1017
/rpt_family="MIR"
/rpt_type=dispersed
variation 1224
/frequency="0.01"
/replace="g"
variation 1701
/frequency="0.02"
/replace="c"
gene 1852..5669
/gene="AGTR2"
mRNA join(1852..1918,2070..2129,3348..5669)
/gene="AGTR2"
/product="angiotensin receptor 2"
variation 2041
/gene="AGTR2"
/frequency="0.41"
/replace="a"
variation 2184
/gene="AGTR2"
/frequency="0.23"
/replace="t"
variation 2318
/gene="AGTR2"
/frequency="0.01"
/replace="a"
variation 2499
/gene="AGTR2"
/frequency="0.01"
/replace="g"
variation 2778
/gene="AGTR2"
/frequency="0.01"
/replace="t"
variation 3161
/gene="AGTR2"
/frequency="0.02"
/replace="a"
CDS 3383..4474
/gene="AGTR2"
/codon_start=1
/product="angiotensin receptor 2"
/protein_id="AAP72969.1"
/translation="MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHL
DAIPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWAT
YYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQA
SYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNIL
GFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLT
FLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFR
VPITWLQGKRESMSCRKSSSLREMETFVS"
variation 3880
/gene="AGTR2"
/frequency="0.02"
/replace="c"
variation 4125
/gene="AGTR2"
/frequency="0.05"
/replace="a"
variation 4393
/gene="AGTR2"
/frequency="0.02"
/replace="a"
variation 4673
/gene="AGTR2"
/frequency="0.15"
/replace="t"
variation 4679
/gene="AGTR2"
/frequency="0.48"
/replace="g"
variation 4975
/gene="AGTR2"
/frequency="0.49"
/replace="c"
variation 5055
/gene="AGTR2"
/frequency="0.05"
/replace="c"
variation 5290
/gene="AGTR2"
/frequency="0.01"
/replace="g"
variation 5311
/gene="AGTR2"
/frequency="0.02"
/replace="c"
variation 5577
/gene="AGTR2"
/frequency="0.29"
/replace="c"
variation 5585
/gene="AGTR2"
/frequency="0.03"
/replace="t"
variation 5659
/gene="AGTR2"
/frequency="0.03"
/replace="t"
variation 5748
/frequency="0.01"
/replace="g"
variation 5792
/frequency="0.02"
/replace="a"
variation 6010
/frequency="0.02"
/replace="c"
variation 6093
/frequency="0.50"
/replace="t"
variation 6303
/frequency="0.48"
/replace="c"
variation 6462
/frequency="0.02"
/replace="a"
variation 6474
/frequency="0.02"
/replace="a"
variation 6481
/frequency="0.06"
/replace="t"
BASE COUNT 1993 a 1236 c 1129 g 2396 t
ORIGIN
1 tgcaaacctt tgaatcctac tgtatttttc acataacgat gacttctcac tgatctcatc
61 tgcctgtgtg ctacagtatt gactttaata ttaatggaga aacagacaga tatcaaaagc
121 catgtgattt gtctcatgcc atttgcaatt ttgtcttctg tcatcaacac tgacttctcc
181 ttccttgttc tgctgaactc catacttagg tgcccagcta cttcctcaga gcctgccctc
241 attctttacc tgtggcctgc agcatggaca ggtgcattct tgctgcttat ctgaaaaata
301 tgatccacag aaataacttg aatctttttg cccatttaaa atgtgctcta ggttctctgg
361 ttctctgtac taactataga aagccatcta gtcacaagtt tctccttcct gtggtctcca
421 tttgggcaat acaattaaga aaaatacgtt tccccacata acaattcttc caattctttt
481 ccccttcttt gatgctttta tgatagatta tgaatggtca tcagtgattt tctgtaaatg
541 ccacgtttcc tttttgccaa gacaaagagt gagactaagg gaccatctag tgcttcctct
601 tgtggtatag aggctaaaca gcgtgagttc tgatattagt ttcctttgat ttaaatgcaa
661 gtgtcttcat ttaatagctg tatgatctca gaaaagttat taaactctat gagtcctagt
721 ttcctgattt gtaaagtggg ggctaatatg aatagcttgt aatagcacct accatatgct
781 aggcatgatt ttaggcactt taaacatatt agctcattta attttccatt agcttattta
841 aaattcctac tctacgatgt aggtaattta tatcattctc ctttctcaga tgagaaactg
901 agacatgaag aagtaaagta acttggccaa ggtcagaatt agtaagtggt agagctgggt
961 ttgtaaagcc aggtagttgg atcccagagg ctatttacta accagtgtgc tatattgcct
1021 ctctattaaa ttattgatga taaataactc atcacagtgt tcggcacata acatttattg
1081 tcagctagta ttatcactac catcacctgt tcttatcttt cttcattttg tcactcttgc
1141 ttctgctgga ttggttgtgt agtttattgc ccccactgcc acaagagaca gcagcaacag
1201 tgatctaggt tgaaatagct agctaatccc tcttcacttt atgtgctttg tatttaaacc
1261 acaaatatga cagagaccta tgaaaggaga ctaaacctct ttttggtcgt gtaaaaatta
1321 tattcctgca atctccaacc ctccagcaac aagccaacaa aaactgcgca aagcaaggga
1381 gaaattttag aagtggtaga cttcaagtaa aattcctacc attctttaat aaacaggggt
1441 aaaaatttca gaaagtaatg aaggttgtga aagctgatga acaaagactt tgctactata
1501 ataaatttcc tagtctctac tcactaattt ctattagaat gccaatatca ggaaaaaagg
1561 aagagaaaat tctgtaaata attactatat ttttctccta ccaagtaagc cactgacttc
1621 aaaattctct agcacatttg tggaaacttc attttttttg tttgagattt atttgaatga
1681 gctgttatga ttggagacag tgagaatttc agattaatgt tttgcagaca aaaaaaaacc
1741 tctctggaaa gctggcaagg gttcataagt cagccctaga attatgtagg ttgaaggctc
1801 ccagtggaca gaccaaacat ataagaagga aaccagagat ctggtgctat tacgtcccag
1861 cgtctgagag aacgagtaag cacagaattc aaagcattct gcagcctgaa ttttgaaggt
1921 aagtatgaac aatttatata taatttactt ggaaagtaga acatacatta aatgaaaata
1981 ttttttatgg atgaacttct gtttttcctg tgttttaaca ctgtattttg caaaactcct
2041 gaattattta gctgctgttt ctcttacagg agtgtgttta ggcactaagc aagctgattt
2101 atgataactg ctttaaactt caacaaccag taagtcttca agtggaattt attattgatt
2161 cttttatgtt aatttgttag gtcaaaagaa aaatctttag agcaaaataa aagttttgct
2221 ctttattagg aggttcttta gatattacac ttttaattgg gtagcttatt tgcacgtatt
2281 ttgaaactat ctaaagtaaa tagtgtttcc tttgtatgct tatctttagc taatgtgttt
2341 ttttttttgg ttttaaaata atgcttctag tgaaaaaaat cacaaaaacc tcaacactgt
2401 aacgtttgag agcaacggct attcagttcg gttaaaccga aaagagagaa aaagaaaaat
2461 gataagacta tatcatgatt aatcattgat gttcatttct catttcactg agcaatctaa
2521 actacttcta cttgaaccta acataggttt ggctgttttt ttctttatct gatttaattg
2581 aaaatggatt gtttagatat taaatagacc aaaattagat atctatatct aaaactaata
2641 ttctctatta aaaggagaag acttagaaat ataaatatat ttcataactt cttcttaact
2701 atattattat tgtgaaaaca atagaaaagt aaaactaaag gaattatttt taattattaa
2761 agacaaacca tgattcccca tcacaatatg ttcctttggc atattctctt ttagtttttt
2821 atatacttat tttttccatt gcttatgtta cttatatttt ccacagctgt agtgatttgt
2881 atgtaattag ttacttaaat agagcatttc tctatgcaat agcaagcagc agtgtggttt
2941 ctagaaagta tacaaacaga gatatatgct caagtgtttt ttgaaagatt aacttttctt
3001 acctctgggt ttcttatttg tttcacacat ttcctgccct gactaatctt ttgaaatatt
3061 aattttcttt aaatctttca aaaacatcat agaaaagatg ggcaaaaggt agttttattc
3121 agaactttga atctctgaaa tgtctttttt ctactatcag gaaaattatt tctccttttt
3181 caagaggtaa aatgaattct tgttttacaa gccatggctc tgtttcttaa tgttttctat
3241 aatcactcac tttttttttg cttttgacaa acattcaaaa tgctaatgat tcaaggatgt
3301 cctcagctct gtatgtgttc taagagttct atgttttttc tccacagaag gcataagaac
3361 taggagctgc tgacatttca atatgaaggg caactccacc cttgccacta ctagcaaaaa
3421 cattaccagc ggtcttcact tcgggcttgt gaacatctct ggcaacaatg agtctacctt
3481 gaactgttca cagaaaccat cagataagca tttagatgca attcctattc tttactacat
3541 tatatttgta attggatttc tggtcaatat tgtcgtggtt acactgtttt gttgtcaaaa
3601 gggtcctaaa aaggtttcta gcatatacat cttcaacctc gctgtggctg atttactcct
3661 tttggctact cttcctctat gggcaaccta ttattcttat agatatgact ggctctttgg
3721 acctgtgatg tgcaaagttt ttggttcttt tcttaccctg aacatgtttg caagcatttt
3781 ttttatcacc tgcatgagtg ttgataggta ccaatctgtc atctacccct ttctgtctca
3841 aagaagaaat ccctggcaag catcttatat agttcccctt gtttggtgta tggcctgttt
3901 gtcctcattg ccaacatttt attttcgaga cgtcagaacc attgaatact taggagtgaa
3961 tgcttgcatt atggctttcc cacctgagaa atatgcccaa tggtcagctg ggattgcctt
4021 aatgaaaaat atccttggtt ttattatccc tttaatattc atagcaacat gctattttgg
4081 aattagaaaa cacttactga agacgaatag ctatgggaag aacaggataa cccgtgacca
4141 agtcctgaag atggcagctg ctgttgttct ggccttcatc atttgctggc ttcccttcca
4201 tgttctgacc ttcctggatg ctctggcctg gatgggtgtc attaatagct gcgaagttat
4261 agcagtcatt gacctggcac ttccttttgc catcctcttg ggattcacca acagctgcgt
4321 taatccgttt ctgtattgtt ttgttggaaa ccggttccaa cagaagctcc gcagtgtgtt
4381 tagggttcca attacttggc tccaagggaa aagagagagt atgtcttgcc ggaaaagcag
4441 ttctcttaga gaaatggaga cctttgtgtc ttaaacgtga gagcaaaatg catgtaatca
4501 acatggctac ttgctttgag gctcaccaga attattttta agtggtttta ataaaataat
4561 aaaatttccc ctaatctttt ctgaatcttc tgaaaccaaa tgtaactatg ttttatcgtc
4621 cagtgacttt caggaattgc ccattgtttt tctgatatgt ttgtacaaga ttgtcattag
4681 tgagacatat ttacaaccta gaagtaactg gtgatatatc tcaaattgta attaataata
4741 gattgtgaat aatgatttgg ggattcagat ttctctttga aacatgcttg tgtttcttag
4801 tggggtttta tatccatttt tatcaggatt tcctcttgaa ccagaaccag tctttcaact
4861 cattgcatca tttacaagac aacattgtaa gagagatgag cacttctaag ttgagtatat
4921 tataatagat tagtactgga ttattcaggc tttaggcata tgcttcttta aaaaagctat
4981 aaattatatt cctcttgcat ttcacttgag tggaggttta tagttaatct ataactacat
5041 attgaatagg gctaggaata tagattaaat catactccta tgctttagct tatttttaca
5101 gttatagaaa gcaagatgta ctataacata gaattgcaat ctataatatt tgtgtgttca
5161 ctaaactctg aataagcact ttttaaaaaa ctttctactc attttaatga ttgtttaaag
5221 gtttctattt tctctgatac ttttttgaaa tcagtaaaca ctgtgtattg ttgtaaaatg
5281 taaaggtcac ttttcacatc cttgactttt tagatgtgct gctttgatat ataggacatt
5341 gatttgattt ttattattaa tgctttggtt ctgggttgtt tcctaaaata tctgggtggc
5401 ttaaaaaaaa ctctttaact tgtaataaac ccttaactgg cataggaaat ggtatccaga
5461 atggaatttt gctacatggg gtctgggtgg gggcaaagag acccagtcaa ttacatgttt
5521 ggtaccaaga aaggaacctg tcagggcagt acaatgtgac tttgaaaata tataccgtgg
5581 gggtagtttt accctatatc tataaacact gtttgttcca gaatctgtat gattctatgg
5641 agctatttta aaccaattgc aggtctagat acctccttct cagcactatt aaagctccta
5701 agttagagga gtgcctaaaa ctgagttacc taaagtttac ttacattaaa gtatgaatat
5761 taattttaga aatttgagac tttattctgt accagccctg tataataaca ggttatctag
5821 gaccttcctc tgaggtaggt ctaaatactg atctctgagg cggaactaac gttttgggga
5881 ctcagcatct ctgccaggtt ccaggattat agacagaaga gtcctgtcat accactttct
5941 ggaaaagtcc taatttcatg taatcctttt attttcaata aaaacaaata gctaaatgta
6001 taaccaacta tgatgttatg ttttcaataa ttttgtaaaa cagctcatat aaataaaatt
6061 tttaattgga agaacattcg tgcttttaaa aagttttttt aactacttct aagtatatat
6121 tctacttcta agtattctta ccttctcttg tatctgtatc ctccatttta tctccactga
6181 tactacttag tttcagctcc gattattact cacctggcct cttgctatac tgttcaagtc
6241 ttcctctctt gagtattgag ccataatttc ccattagcta tgaaagcaaa atccaacttt
6301 cttcgagtct gcaagacctt gggagatgtg actcttccta gtctttctgg actttttctc
6361 tctgtcacac ctcttcaaac cctgtgttta agcatcaaaa aatgacttaa tgctttttaa
6421 agcctaatgc cctttcgtgc ctctctgctg ttgttcacac agctccatct tactaaacac
6481 ccctccaatc attctcacct cctcagggcc tcacattcaa gtgatgaaaa tctgctcaac
6541 tttcgacatt cagctcatgc tatttcctct accataataa taattattat actaattata
6601 atactacacc cctagaattt cctttaatga acagaattgc ttctctagtt tttgggatgt
6661 taagcctgat gtctgctttt atagaagccc aatgttgaac cctgagtagt agcctccaag
6721 tggtttttct tggactaaga agaaatgcca gttg
//