LOCUS AY323817 1566 bp mRNA linear HUM 22-SEP-2003
DEFINITION Homo sapiens cytochrome P450 2R1 (CYP2R1) mRNA, complete cds.
ACCESSION AY323817
VERSION AY323817.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1566)
AUTHORS Cheng,J.B., Motola,D.L., Mangelsdorf,D.J. and Russell,D.W.
TITLE De-orphanization of cytochrome P450 2R1: a microsomal vitamin D
25-hydroxilase
JOURNAL J. Biol. Chem. 278 (39), 38084-38093 (2003)
PUBMED 12867411
REFERENCE 2 (bases 1 to 1566)
AUTHORS Cheng,J.B.
TITLE Direct Submission
JOURNAL Submitted (14-JUN-2003) Molecular Genetics, UT Southwestern Medical
Center, 5323 Harry Hines Blvd., Dallas, TX 75390, USA
FEATURES Location/Qualifiers
source 1..1566
/db_xref="H-InvDB:HIT000251747"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="11"
/map="11p15.2"
gene 1..1566
/gene="CYP2R1"
CDS 1..1506
/gene="CYP2R1"
/codon_start=1
/product="cytochrome P450 2R1"
/protein_id="AAQ23114.1"
/translation="MWKLWRAEEGAAALGGALFLLLFALGVRQLLKQRRPMGFPPGPP
GLPFIGNIYSLAASSELPHVYMRKQSQVYGEIFSLDLGGISTVVLNGYDVVKECLVHQ
SEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHRRLAVNSFRYFGYGQKSFESKILE
ETKFFNDAIETYKGRPFDFKQLITNAVSNITNLIIFGERFTYEDTDFQHMIELFSENV
ELAASASVFLYNAFPWIGILPFGKHQQLFRNAAVVYDFLSRLIEKASVNRKPQLPQHF
VDAYLDEMDQGKNDPSSTFSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQG
QVQKEIDLIMGPNGKPSWDDKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGY
SIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLG
EHLARMEMFLFFTALLQRFHLHFPHELVPDLKPRLGMTLQPQPYLICAERR"
BASE COUNT 430 a 325 c 349 g 462 t
ORIGIN
1 atgtggaagc tttggagagc tgaagagggc gcggcggcgc tcggcggcgc gctcttcctg
61 ctgctcttcg cgctaggggt ccgccagctg ctgaagcaga ggcggccgat gggcttcccc
121 ccggggccgc cggggctgcc atttatcggc aacatctatt ccctggcagc ctcatccgag
181 cttccccatg tctacatgag aaagcagagc caggtgtacg gagagatctt cagtttagat
241 cttggaggca tatcaactgt ggttctaaat ggctatgatg tagtaaagga atgccttgtt
301 catcaaagcg aaatttttgc agacagacca tgccttcctt tattcatgaa gatgacaaaa
361 atgggaggct tactcaattc cagatatggc cgaggatggg ttgatcacag acgattagct
421 gtaaacagtt ttcgatattt tggatatggc caaaagtctt ttgaatctaa aatcttggaa
481 gaaaccaaat ttttcaatga tgctattgaa acatacaaag gtagaccttt tgactttaaa
541 cagttaataa cgaatgctgt ttcaaacata accaatctga tcatttttgg agaacgattc
601 acttatgaag acaccgattt tcagcacatg attgagttat ttagtgaaaa tgtggaacta
661 gctgccagtg cctcagtctt cttgtataat gcctttccat ggattggcat cctgcctttt
721 ggaaaacatc aacagctgtt tagaaatgca gctgtagtct atgattttct ctccagactc
781 attgaaaaag cttcagtcaa cagaaagcct cagctacctc agcattttgt tgatgcttat
841 ttagatgaga tggatcaagg taaaaatgac ccatcatcta ctttctccaa agaaaaccta
901 attttctcag tgggtgaact catcattgct ggaactgaaa ctacaaccaa tgtgctacgg
961 tgggcgattc ttttcatggc cctttatcct aatattcaag gacaagttca gaaagagatt
1021 gatttaatta tgggccctaa tgggaagcct tcttgggacg acaaatgcaa aatgccttat
1081 actgaggcag ttttgcatga agttttaaga ttctgtaata tagttccatt agggattttc
1141 catgcaacct ctgaagatgc agttgtacgt ggttattcca ttcctaaagg cacaacagta
1201 attacaaatc tttattctgt acactttgat gaaaagtact ggagagaccc agaagtgttc
1261 catcctgagc gatttctgga cagcagtgga tattttgcca agaaggaagc tttggttcct
1321 ttttccctag gaagaagaca ttgtcttgga gaacacttgg ctcggatgga aatgttcttg
1381 ttttttacag cattgcttca gaggtttcat ttgcattttc cacatgaact agttccagat
1441 ctgaagccca ggttaggcat gacattgcag ccccaaccct acctcatctg tgctgaaaga
1501 cgctgaaact gcctgggatg ttttcgggaa caagaatgta tatttgcctt atccctgaac
1561 ttggtt
//