LOCUS AY320284 3173 bp mRNA linear HUM 10-AUG-2007
DEFINITION Homo sapiens PACS2 mRNA, complete cds.
ACCESSION AY320284
VERSION AY320284.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3173)
AUTHORS Simmen,T., Aslan,J.E., Blagoveshchenskaya,A.D., Thomas,L., Wan,L.,
Xiang,Y., Feliciangeli,S.F., Hung,C.H., Crump,C.M. and Thomas,G.
TITLE PACS-2 controls endoplasmic reticulum-mitochondria communication
and Bid-mediated apoptosis
JOURNAL EMBO J. 24 (4), 717-729 (2005)
PUBMED 15692567
REMARK Erratum:[EMBO J. 2005 Mar 23;24(6):1301]
REFERENCE 2 (bases 1 to 3173)
AUTHORS Xiang,Y., Wan,L., Simmen,T. and Thomas,G.
TITLE Direct Submission
JOURNAL Submitted (10-JUN-2003) Vollum Institute, Oregon Health and
Sciences University, 3181 Sam Jackson Park Road, Portland, OR
97239, USA
REFERENCE 3 (bases 1 to 3173)
AUTHORS Xiang,Y., Wan,L., Simmen,T. and Thomas,G.
TITLE Direct Submission
JOURNAL Submitted (10-AUG-2007) Vollum Institute, Oregon Health and
Sciences University, 3181 Sam Jackson Park Road, Portland, OR
97239, USA
REMARK Sequence update by submitter
COMMENT On Aug 10, 2007 this sequence version replaced AY320284.1.
FEATURES Location/Qualifiers
source 1..3173
/db_xref="H-InvDB:HIT000251713"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="14"
/map="14q32"
CDS 504..3173
/note="PACS-2; early secretory pathway sorting connector"
/codon_start=1
/product="PACS2"
/protein_id="AAQ83882.2"
/translation="MAERGRLGLPGALGALNTPVPMNLFATWEVDGSSPSCVPRLCSL
TLKKLVVFKELEKELISVVIAVKMQGSKRILRSHEIVLPPSGQVETDLALTFSLQYPH
FLKREGNKLQIMLQRRKRYKNRTILGYKTLAAGSISMAEVMQHPSEGGQVLSLCSSIK
EAPVKAAEIWIASLSSQPIDHEDSTMQAGPKAKSTDNYSEEEYESFSSEQEASDDAVQ
GQDLDEDDFDVGKPKKQRRSIVRTTSMTRQQNFKQKVVALLRRFKVSDEVLDSEQDPA
EHIPEAEEDLDLLYDTLDMEHPSDSGPDMEDDDSVLSTPKPKLRPYFEGLSHSSSQTE
IGSIHSARSHKEPPSPADVPEKTRSLGGRQPSDSVSDTVALGVPGPREHPGQPEDSPE
AEASTLDVFTERLPPSGRITKTESLVIPSTRSEGKQAGRRGRSTSLKERQAARPQNER
ANSLDNERCPDARSQLQIPRKTVYDQLNHILISDDQLPENIILVNTSDWQGQFLSDVL
QRHTLPVVCTCSPADVQAAFSTIVSRIQRYCNCNSQPPTPVKIAVAGAQHYLSAILRL
FVEQLSHKTPDWLGYMRFLVIPLGSHPVARYLGSVDYRYNNFFQDLAWRDLFNKLEAQ
SAVQDTPDIVSRITQYIAGANCAHQLPIAEAMLTYKQKSPDEESSQKFIPFVGVVKVG
IVEPSSATSGDSDDAAPSGSGTLSSTPPSASPAAKEASPTPPSSPSVSGGLSSPSQGV
GAELMGLQVDYWTAAQPADRKRDAEKKDLPVTKNTLKCTFRSLQVSRLPSSGEAAATP
TMSMTVVTKEKNKKVMFLPKKAKDKDVESKSQCIEGISRLICTARQQQNMLRVLIDGV
ECSDVKFFQLAAQWSSHVKHFPICIFGHSKATF"
BASE COUNT 610 a 1091 c 1021 g 451 t
ORIGIN
1 ggtggacccc cacgactctc ccggcccttg cccgcggctc ccggggggcg gggcggggcg
61 ccccgggcgg ggtctgtgcg caggcgcgtg agtgcgcgct ctcgcgcacc ggcgggcggg
121 gacgccccgt gaggcgccgt cggaggaagc gcgcgcgcac ctcacttccg gcgcgcgctg
181 cgccggcggc gatttggacc cgaggcggcg agctggcgcc ccgcccagcc aatcggcggc
241 gcggcgcggg tcggagggcg ccgggcgcgc gcggggcggc cgggggcgcg cggggcgcgt
301 gcggggcgcc gggcggggcg gggcggacgg ccgcagctcg tcgccgcccg cgggcctgtc
361 cgacgccggg gcccggcccg tcccctccgc cgcccggcag ccatgtgacc gcgccgccgc
421 cctccgcgcg cccggcccgc ccgccgcgcg tccgcggccc ggccgcagcc ccaggccgcc
481 gagggagcgg cggggccggc gccatggccg agcgaggccg cctcggcctc cccggcgcgc
541 tcggcgcgct caacacgccc gtgcccatga acctgttcgc cacctgggag gtggacggct
601 ccagccccag ctgcgtgccc aggttgtgca gcctgactct gaagaagctg gtggtcttca
661 aggagctgga gaaggagctg atctccgtgg tgatcgctgt caagatgcag ggctccaaac
721 gaatcctgcg gtcccatgag attgtgctgc cccccagtgg acaagtggag acagacctgg
781 ccctgacctt ctccttgcag tatcctcact tcttgaagag ggaaggcaac aagcttcaga
841 tcatgctgca gcgcagaaag cgctacaaga acagaaccat cctgggctac aagacgctgg
901 ccgcgggctc catcagcatg gctgaggtga tgcaacaccc gtctgaaggt ggccaggtgc
961 tgagcctctg cagcagcatc aaggaggccc ccgtcaaggc ggccgagatc tggatcgcct
1021 ccctgtccag ccagcccatt gaccacgaag acagcaccat gcaggccggc cccaaggcca
1081 agtccacgga taactactcc gaggaggagt atgagagctt ctcctccgag caggaggcca
1141 gtgacgacgc cgtgcagggg caggacttgg acgaggacga ctttgacgtg gggaagccga
1201 agaagcagcg gagatcgatt gtaagaacga cgtccatgac caggcaacag aacttcaagc
1261 agaaagtggt agcgctgctg cggaggttca aagtgtccga cgaggtcctg gactcggagc
1321 aggaccctgc ggagcacatc cccgaggcag aggaggacct ggacctcctg tatgacaccc
1381 tggacatgga gcaccccagc gacagcggcc ccgacatgga ggatgacgac agcgtcctca
1441 gcacccccaa gccgaagctg cggccatact ttgaaggcct gtcgcactcg agctcgcaga
1501 cggagattgg gagcatccac agcgcccgca gccacaagga gcccccaagc ccggctgacg
1561 tgcccgagaa gacgcggtcc ctgggaggca ggcagccgag cgacagtgtc tctgacacgg
1621 tggccctcgg tgtgccaggc ccgagggagc accctggaca gcctgaggac agccccgagg
1681 ctgaggcctc caccctggat gtgttcacgg agaggctgcc gcccagcggg aggatcacca
1741 agacagagtc ccttgtcatc ccctccacca ggtccgaagg gaagcaggct ggccgacggg
1801 gccggagcac atccttgaag gagcggcagg cagcacggcc ccagaatgag cgggccaaca
1861 gcctggacaa cgagcgctgc ccggacgccc ggagccagct acagatcccc aggaagactg
1921 tgtatgacca gctcaaccac atcctcatct ccgatgacca gcttcccgaa aacatcatcc
1981 ttgtcaacac ctccgactgg caggggcagt tcctctccga cgtcctgcag aggcacacgc
2041 tccccgtggt gtgcacgtgc tctcctgcgg acgtccaggc ggccttcagc accatcgtct
2101 cacggataca gagatactgc aactgcaatt cccagccccc gacccccgtg aagatcgccg
2161 tggcgggagc gcagcattac ctcagtgcca tcctgcggct ctttgtggag cagctgtccc
2221 acaagacacc cgactggctc ggctacatgc gcttcctggt catcccactg ggctcccacc
2281 ccgtggccag gtacctaggc tccgtggact accgctacaa caacttcttc caggacctgg
2341 cctggagaga cctgttcaac aagctggagg cccagagtgc ggtacaggac acgccagaca
2401 ttgtgtcacg catcacgcag tacatcgcag gggccaactg tgcccaccag ctccccatcg
2461 cagaggccat gctgacctac aagcagaaga gccctgacga agagtcctcc caaaagttca
2521 ttccctttgt cggggttgtg aaggttggaa ttgtggagcc atcttcggcc acatcaggcg
2581 actcggacga cgcggccccc tcgggctctg gcacgctctc atccaccccg ccgtccgcat
2641 ctcctgcggc caaggaggcc tcacccaccc cgccctcctc cccgtcggtg agcggaggcc
2701 tgtcctcccc cagccagggt gtcggcgccg agctgatggg gctgcaggtg gactactgga
2761 cggcagcaca gcctgcggac aggaagaggg acgccgagaa gaaggacctg cctgtcacca
2821 aaaacacgct caagtgcact ttccggtccc tccaggtcag caggctgccc agcagcggcg
2881 aggctgcagc cacgcccacc atgtccatga ccgtggtcac caaggagaag aacaagaagg
2941 tgatgtttct gcccaagaaa gcgaaggaca aggacgtgga gtctaagagc cagtgcattg
3001 agggcatcag ccggctcatc tgcactgcca ggcagcagca gaacatgctg cgggtcctca
3061 tcgacggcgt ggagtgcagc gacgtcaagt tcttccagct ggccgcgcag tggtcctcgc
3121 acgtgaagca cttccccatc tgcatcttcg gacactccaa ggccaccttc tag
//