LOCUS AY299089 2123 bp mRNA linear HUM 17-JUN-2003
DEFINITION Homo sapiens SPRED1 mRNA, complete cds.
ACCESSION AY299089
VERSION AY299089.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2123)
AUTHORS King,J.A.J., Hall,N. and Hovens,C.M.
TITLE Direct Submission
JOURNAL Submitted (15-MAY-2003) Surgery, University of Melbourne, Royal
Parade, Parkville, VIC 3050, Australia
FEATURES Location/Qualifiers
source 1..2123
/db_xref="H-InvDB:HIT000251502"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="15"
/map="15q14"
/cell_type="glioblastoma"
CDS 336..1670
/note="EVH1/Sprouty domain containing protein; suppressor
of Ras/MAPK activation"
/codon_start=1
/product="SPRED1"
/protein_id="AAP59414.1"
/translation="MSEETGLSDNDNSYARVRAVVMTRDDSSGGWLPLGGSGLSSVTV
FKVPHQEENGCADFFIRGERLRDKMVVLECMLKKDLIYNKVTPTFHHWKIDDKKFGLT
FQSPADARAFDRGIRRAIEDISQGCPESKNEAEGADDLQANEEDSSSSLVKDHLFQQE
TVVTSEPYRSSNIRPSPFEDLNARRVYMQSQANQITFGQPGLDIQSRSMEYVQRQISK
ECGSLKSQNRVPLKSIRHVSFQDEDEIVRINPRDILIRRYADYRHPDMWKNDLERDDA
DSSIQFSKPDSKKSDYLYSCGDETKLSSPKDSVVFKTQPSSLKIKKSKRRKEDGERSR
CVYCQERFNHEENVRGKCQDAPDPIKRCIYQVSCMLCAESMLYHCMSDSEGDFSDPCS
CDTSDDKFCLRWLALVALSFIVPCMCCYVPLRMCHRCGEACGCCGGKHKAAG"
BASE COUNT 574 a 432 c 548 g 569 t
ORIGIN
1 ggctggagga gcagctctcc agtcagcctt tgcagcccct ctctttttcc ctttccaccg
61 ggcctcctcg gatcccttgg ctgggcactg aggcggggga agaggctggg gtcgccacgg
121 cggaggttgc ttggccgcca cccccctgcg ggggtggccg gggttcccgg ctggggggta
181 ccgtctctgg gtgaggcatc caccatggtg aggcccctgt gcctgtgccc ccgggccccc
241 cgggcgccgt gccttccttg cccccttcgg tgctgctgtt gctcccccgc tgtgttgctc
301 ctcaatctcc agatcggatc acggtgaggg aaacgatgag cgaggagacg ggactttctg
361 acaacgataa tagttatgca cgagtgcgag ctgtggtgat gacccgagat gactcaagtg
421 gtggatggtt accacttgga gggagtggac taagcagcgt cactgtcttc aaagtccctc
481 atcaggaaga gaatggctgt gctgactttt ttatccgtgg agagcgactc agggacaaaa
541 tggtggtttt ggaatgtatg cttaaaaaag acctcattta taataaggtc actccaacat
601 ttcaccactg gaagattgat gacaagaagt ttggtcttac gtttcaaagt cctgctgatg
661 ctagggcttt tgatagaggt atccgaagag ctatagagga tatttctcaa ggatgccccg
721 aatcaaaaaa tgaagctgaa ggggcagatg acttacaagc aaatgaagag gattcttcca
781 gttctctagt gaaggatcac ctttttcagc aagagacagt tgttaccagt gagccttata
841 gaagctcaaa tataagacct tctccctttg aagatctgaa tgccagaaga gtctacatgc
901 aaagccaagc caatcagata acatttggtc agccaggctt ggacattcag agcagaagta
961 tggaatacgt acagcggcaa atatccaagg aatgtggaag cctaaagtcc caaaataggg
1021 tccctttgaa atcaatcaga catgtcagct ttcaagatga ggatgagatt gtcagaataa
1081 accctcgaga tatcttaata cgtcgctatg cagactacag acatcctgac atgtggaaaa
1141 atgacttgga aagagatgat gctgattcca gtattcagtt ttctaaacca gacagtaaaa
1201 aatcagacta tctgtactct tgtggggatg agactaagtt aagttcaccc aaagactctg
1261 tggtatttaa gacgcagcct tcctcattaa aaattaagaa gtcaaaacga agaaaagagg
1321 atggtgaacg ttctcgctgc gtatactgcc aggaaaggtt taatcatgaa gaaaatgtta
1381 ggggaaaatg tcaggatgct ccagacccta ttaaaagatg catatatcaa gttagttgca
1441 tgctctgtgc agagagcatg ttgtatcatt gtatgtcaga ctcagaggga gatttttctg
1501 atccctgttc gtgtgacact agcgacgaca agttctgctt gcgatggtta gccctggtag
1561 ctttgtcttt cattgtacca tgtatgtgct gctacgtccc tttgagaatg tgccatcgct
1621 gtggtgaggc atgtggttgc tgtggtggga aacataaagc tgctggatga aatggtccag
1681 tgccaaaatg agcttaaaat cttgtttcca ggaattagct aactttggat ttgtggaagc
1741 ttttggcaag caatatggaa tcttgcctgg tatcattgag cccacacatg gaggaagcag
1801 aactcatcag ttcttggcgt ttcacgccat gcctaacttt tcccttgagt gcatggcatg
1861 tttgttacag gtgtagagta ttgcagaagg aaaccatttc tggttattgt ggtataaaaa
1921 gtcaggcata aaatatgatc caataaaagg gattaatttt gggcattttg ttatatttat
1981 gcatttaggt gatgggactt ttaaagggtt gaatttatag gacacgaact taaaaattaa
2041 aagtgcctta ggggacagtt gatttcatct aagaaaagtt accttgggaa ttcagagtaa
2101 acaggcctaa tctttatagg ttg
//