LOCUS AY281131 3750 bp mRNA linear HUM 16-JUN-2009
DEFINITION Homo sapiens AIDA-1b mRNA, complete cds.
ACCESSION AY281131
VERSION AY281131.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3750)
AUTHORS Ghersi,E., Vito,P., Lopez,P., Abdallah,M. and D'Adamio,L.
TITLE The intracellular localization of amyloid beta protein precursor
(AbetaPP) intracellular domain associated protein-1 (AIDA-1) is
regulated by AbetaPP and alternative splicing
JOURNAL J. Alzheimers Dis. 6 (1), 67-78 (2004)
PUBMED 15004329
REFERENCE 2 (bases 1 to 3750)
AUTHORS Ghersi,E. and D'Adamio,L.
TITLE Direct Submission
JOURNAL Submitted (22-APR-2003) Microbiology & Immunology, Albert Einstein
College of Medicine, 1300 Morris Park Avenue, Ullmann 1209, Bronx,
NY 10461, USA
FEATURES Location/Qualifiers
source 1..3750
/db_xref="H-InvDB:HIT000251382"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="12"
/map="12q23.1"
CDS 1..3750
/note="amyloid-beta precursor protein intracellular domain
associated protein-1b"
/codon_start=1
/product="AIDA-1b"
/protein_id="AAP37612.1"
/translation="MGKDQELLEAARTGNVALVEKLLSGRKGGILGGGSGPLPLSNLL
SIWRGPNVNCTDSSGYTALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWK
GDVEIVKILIHHGPSHSRVNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSK
LETPLDLAALYGRLRVVKMIISAHPNLMSCNTRKHTPLHLAARNGHKAVVQVLLEAGM
DVSCQTEKGSALHEAALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEHPSQKSLQ
IATLLQEYLEGVGKYATVLEEPVQEDATQETHISSPVESPSQKTKSETVTGELSKLLD
EIKLCQEKDYSFEDLCHTISDHYLDNLSKISEEELGKNGSQSVRTSSTINLSPGEVEE
EDDDENTCGPSGLWEALTPCNGCRNLGFPMLAQESYPKKRNYTMEIVPSASLDTFPSE
NENFLCDLMDTAVTKKPCSLEIARAPSPRTDNASEVAVTTPGTSNHRNSSTGPTPDCS
PPSPDTALKNIVKVIRPQPKQRTSIVSSLDFHRMNHNQEYFEINTSTGCTSFTASPPA
SPPTSSVGTTEVKNEGTNHTDDLSRQDDNDPPKEYDPGQFAGLLHGSSPACESPENPF
HLYGKREQCEKGQDEVSLANSPLPFKQSPIENNSEPLVKKIKPKVVSRTIFHKKSNQL
ENHTIVGTRSTRSGSRNGDQWVMNAGGFVERACTLGRIRSLPKALIDMHLSKSVSKSD
SDLIAYPSNEKTSRVNWSESSTAEHSSKGNSERTPSFTSEWEEIDKIMSSIDVGINNE
LKEMNGETTRPRCPVQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEI
GILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSM
DLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQKPPRSITLREPSGNHTPP
QLSPSLSQSTYTTGGSLDVPHIIMQGDARRRRNENYFDDIPRSKLERQMAQTGDWGEP
SITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAK
MRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLST
FAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTLPE
SFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF"
BASE COUNT 1178 a 867 c 819 g 886 t
ORIGIN
1 atggggaagg accaggagct gctggaagct gctcgcactg gaaatgtggc tctggtggag
61 aaactcctgt ctggcaggaa aggagggatc ctgggcggtg gatccggacc cctgcccctg
121 tctaatctgc taagcatctg gcgaggcccc aatgtgaact gcacagacag ttcgggttac
181 actgctttac accacgcagc cttaaatgga cataaggaca tagttctcaa actacttcag
241 tatgaggcat caacaaatgt agcagacaac aaagggtatt ttcctattca cctggctgcc
301 tggaaaggag atgtggaaat tgtgaagatt cttattcatc atggaccatc acattccagg
361 gtcaatgaac agaacaatga aaatgaaact gccctacact gtgcagctca atatggacac
421 tcagaagtag ttgctgttct cctagaagag ctcactgacc cgacaattag aaatagcaag
481 ctggaaacac ctttggactt ggcggcactc tacggacggc ttagagtggt aaaaatgatc
541 atcagtgcac atcctaactt aatgagctgc aacactcgca agcacacgcc acttcacctt
601 gctgcgcgca atggccacaa agcagtcgtg caggtgctgc tggaggcagg aatggatgtg
661 agctgtcaaa cagaaaaggg gagtgcactt catgaagcag ctttgtttgg aaaggtggat
721 gttgtacgag ttctgttaga aacaggaatt gatgccaaca taaaggatag cttaggtaga
781 actgtcttgg acattctgaa agaacatcca tctcagaaat ctctccagat tgcaacactc
841 ttacaagagt atttagaagg cgtgggtaag tatgctacag tcctcgaaga gcctgtacag
901 gaagatgcaa cacaagaaac acacatttca tctcctgttg agtctccttc ccaaaagacc
961 aaaagtgaaa ccgtcactgg agaattatca aaactcttgg atgaaataaa actctgtcaa
1021 gaaaaggatt attcgtttga agacttgtgc cacacaatat cagaccacta cttagataat
1081 ttgagcaaga tttcagagga agaacttggg aaaaatggaa gccagagtgt aagaacctca
1141 tctacaatca atttgtcacc aggagaagtg gaagaagagg atgatgatga aaatacgtgt
1201 gggccatcag gactttggga agcattaact ccgtgtaatg gatgtaggaa ccttggcttc
1261 cccatgcttg cccaggagtc ctatccaaag aagagaaatt acactatgga aattgtacca
1321 tctgcttctc tggatacatt tccttcagaa aatgagaact ttctgtgtga tctcatggac
1381 acagctgtta caaagaaacc ttgctcctta gaaattgcaa gggcaccttc cccaagaact
1441 gataatgcct ctgaggtagc agttactact ccaggaacta gtaaccatag aaacagctca
1501 acaggcccaa cacctgattg ttcacctcca tcccctgata ctgccctcaa aaatattgta
1561 aaagtcattc gaccccagcc taaacagcga acatccattg tgtcttctct ggattttcac
1621 cgaatgaatc acaaccaaga atattttgaa atcaacacat ctacagggtg cacaagcttt
1681 actgccagtc ctcctgctag tccacccacc tcttctgtgg gaaccacaga agtcaagaat
1741 gagggaacta accatacaga tgacctctcc cgacaggatg acaatgatcc cccaaaagaa
1801 tatgatcctg ggcaatttgc aggcctgctc catggatcct ctccagcctg tgagtcccct
1861 gaaaatccat ttcatctcta tgggaaaaga gaacaatgtg aaaaaggaca agatgaagtc
1921 agtttggcaa acagtccttt gcctttcaag cagtctccaa tagaaaataa ctcagaacct
1981 ttggtaaaga aaattaaacc caaagtggtc agtagaacaa tttttcacaa aaaaagcaac
2041 caactcgaaa accataccat tgttggcaca agatcaacca ggagtggatc tcggaatggg
2101 gaccagtggg ttatgaacgc agggggattt gtggagagag cctgtactct ggggagaata
2161 aggtcattgc ctaaagcctt gatcgacatg catttgtcaa aaagtgtctc taaatctgat
2221 tctgatctca ttgcctatcc ttccaatgag aaaacatcaa gagttaactg gagtgaatct
2281 tccactgctg aacacagttc taaagggaat tctgaaagaa caccatcctt cacatcggaa
2341 tgggaagaaa ttgacaaaat aatgagttcc atagatgttg gaatcaacaa cgaacttaaa
2401 gagatgaatg gtgagaccac aagacccaga tgccctgtcc aaacagtggg acaatggttg
2461 gaaagcattg ggctacctca gtacgagaac cacctgatgg ctaatggatt tgacaatgtg
2521 cagtttatgg gaagcaatgt tatggaagat caggatttgt tggaaattgg aatccttaat
2581 tctgggcaca gacaaagaat tctacaggca atccagctcc ttccaaagat gagacccatt
2641 gggcatgatg gctaccatcc cacctctgta gctgagtggc tggattccat tgaactgggc
2701 gactacacca aagcctttct aattaatggc tacacttcga tggacctgtt gaaaaaaatc
2761 tgggaggttg aacttattaa tgttttaaaa atcaatttga ttggccacag gaaacgtatt
2821 ttggcatctc tgggagacag gctgcacgac gatcccccac agaagccccc tcggtccatc
2881 accctcaggg aacccagtgg taatcacact cctcctcagt tgtctccatc acttagccaa
2941 agcacttaca ccactggtgg ctccctagac gttcctcaca ttatcatgca gggcgatgca
3001 aggaggagaa gaaatgaaaa ctactttgat gatattcccc gatcaaaact ggagaggcag
3061 atggctcaga caggagactg gggagaacct tccattacct tgcgacctcc gaatgaagcc
3121 acagcctcta ccccggtaca gtactggcag catcacccag aaaagcttat cttccagtcg
3181 tgtgattaca aagcttttta tttaggttct atgctgataa aagagcttag ggggacagaa
3241 tcaacccaag atgcttgtgc aaaaatgcgg gctaactgtc agaagtctac agagcaaatg
3301 aagaaggtcc ctactattat tctttctgtc tcatataaag gagtcaaatt tattgatgca
3361 acaaataaga acataattgc tgagcatgaa attcgtaata tctcctgtgc tgcccaggac
3421 ccagaagacc tctcaacatt tgcctatatc acaaaagatt tgaagtctaa tcaccactac
3481 tgtcatgtgt ttactgcctt tgatgtgaat ttagcctatg aaatcatcct aaccctggga
3541 caggcattcg aagtcgctta ccagctagca ctacaagcaa gaaaaggggg acactcctcc
3601 acacttccag aaagctttga aaacaaaccc tccaaaccca tccccaagcc ccgcgttagc
3661 attcgcaagt ccgtggatct tcttcatgcc agccataccg ggcaggaacc atcagagaga
3721 cacactgagg aggcactcag aaaattttga
//