LOCUS AY267371 2079 bp mRNA linear HUM 01-MAY-2003
DEFINITION Homo sapiens NIMA-family kinase NEK8 (NEK8) mRNA, complete cds.
ACCESSION AY267371
VERSION AY267371.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2079)
AUTHORS Nedwidek,M.N., Roig,J., Lenz,G. and Avruch,J.
TITLE NIMA-family kinase Nek8 complete human coding region
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 2079)
AUTHORS Nedwidek,M.N., Roig,J., Lenz,G. and Avruch,J.
TITLE Direct Submission
JOURNAL Submitted (02-APR-2003) Massachusetts General Hospital Molecular
Biology, Harvard Medical School, 50 Blossom Street, Wellman 11th
Floor, Boston, MA 02114, USA
FEATURES Location/Qualifiers
source 1..2079
/db_xref="H-InvDB:HIT000085665"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="17"
/map="17q11.1"
/clone_lib="Clontech Homo sapiens Placental MTC tissue
panel Cat No. K1420-1"
gene 1..2079
/gene="NEK8"
CDS 1..2079
/gene="NEK8"
/note="Never In Mitosis gene A family protein kinase;
regulator of chromosome condensation 1"
/codon_start=1
/product="NIMA-family kinase NEK8"
/protein_id="AAP04006.1"
/translation="MEKYERIRVVGRGAFGIVHLCLRKADQKLVIIKQIPVEQMTKEE
RQAAQNECQVLKLLNHPNVIEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSLLEE
ETILHFFVQILLALHHVHTHLILHRDLKTQNILLDKHRMVVKIGDFGISKILSSKSKA
YTVVGTPCYISPELCEGKPYNQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSG
TFAPISDRYSPELRQLVLSLLSLEPAQRPPLSHIMAQPLCIRALLNLHTDVGSVRMRR
AEKSVAPSNTGSRTTSVRCRGIPRGPVRPAIPPPLSSVYAWGGGLGTPLRLPMLNTEV
VQVAAGRTQKAGVTRSGRLILWEAPPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGVT
IKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQPTIVEALLGYEMVQVAC
GASHVLALSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEAQRVVCGIDSSM
ILTVPGQALACGSNRFNKLGLDHLSLGEEPVPHQQVEEALSFTLLGSAPLDQEPLLSI
DLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRGSRAPCKVQGLEGIKMAMVACGDAF
TVAIGAESEVYSWGKGARGRLGRRDEDAGLPRPVQLDETHPYTVTSVSCCHGNTLLAV
RSVTDEPVPP"
misc_feature 1..777
/gene="NEK8"
/note="Region: protein kinase domain"
misc_feature 934..2076
/gene="NEK8"
/note="Region: RCC1 domain"
BASE COUNT 429 a 631 c 622 g 397 t
ORIGIN
1 atggagaagt acgagcggat ccgagtggtg gggagaggtg ccttcgggat tgtgcacctg
61 tgcctgcgaa aggctgacca gaagctggtg atcatcaagc agattccagt ggaacagatg
121 accaaggaag agcggcaggc agcccagaat gagtgccagg tcctcaagct gctcaaccac
181 cccaatgtca ttgagtacta cgagaacttc ctggaagaca aagcccttat gatcgccatg
241 gaatatgcac caggcggcac tctggctgag ttcatccaaa agcgctgtaa ttccctgctg
301 gaggaggaga ccatcctgca cttcttcgtg cagatcctgc ttgcactgca tcatgtgcac
361 acccacctca tcctgcaccg agacctcaag acccagaaca tcctgcttga caaacaccgc
421 atggtcgtca agatcggtga tttcggcatc tccaagatcc ttagcagcaa gagcaaggcc
481 tacacggtgg tgggtacccc atgctatatc tcccctgagc tgtgtgaggg caagccctac
541 aaccagaaga gtgacatctg ggccctgggc tgtgtcctct acgagctggc cagcctcaag
601 agggctttcg aggctgcgaa cttgccagca ctggtgctga agatcatgag tggcaccttt
661 gcacctatct ctgaccggta cagccctgag cttcgccagc tggtcctgag tctactcagc
721 ctggagcctg cccagcggcc accactcagc cacatcatgg cacagcccct ctgcatccgt
781 gccctcctca acctccacac cgacgtgggc agtgtccgca tgcggagggc agagaagtcc
841 gtggccccca gcaacacagg gagcaggacc accagtgtcc gctgcagagg tatcccccgg
901 ggacctgtga ggccagccat cccaccacca ctgtcgtcag tgtatgcctg gggtggtggg
961 ctgggcaccc ccctgcggct gccaatgctc aacacagagg tggtccaggt ggcagctggg
1021 cgcacgcaga aagccggcgt cacgcgctct gggcgtctca tcctgtggga ggccccaccc
1081 ctaggtgcag gcggaggcag tctccttcct ggggcagtgg agcagccaca gccccagttc
1141 atctcgcgtt tcctggaggg ccagtcgggt gtgaccatca agcacgtggc ctgtggggac
1201 ttcttcactg cctgcctgac tgacagaggc atcatcatga cattcggcag cggcagcaat
1261 gggtgcctag gccatggcag cctcactgac atcagccagc ccaccattgt ggaggctttg
1321 ctgggctatg aaatggtgca ggtggcctgt ggggcctctc acgtgctggc cctgtccact
1381 gagcgagaac tatttgcctg gggccgtgga gacagcggca gactggggct aggcaccagg
1441 gagtcccaca gctgccccca gcaggtgccc atgcccccag gacaggaagc tcagcgagtt
1501 gtatgtggta tcgattcctc catgatcctc actgtgcctg gccaagccct agcctgtggg
1561 agcaacaggt tcaacaagct gggcctggac cacctctccc tgggggagga gcctgtcccc
1621 caccagcaag tggaggaggc cctgagcttc acactactag gctctgcacc cctggaccag
1681 gagcctctgc tgagtataga cctgggcact gctcactcag ctgctgtgac tgcctcgggt
1741 gattgctaca cttttggcag caatcagcac ggacagttgg gcaccaatac tcgccgaggc
1801 agtcgggcac cctgtaaggt ccaaggcctt gagggcatca agatggcaat ggtagcctgt
1861 ggggatgcct tcactgtagc tattggggca gagagcgaag tgtactcttg gggcaaaggg
1921 gcgcgaggtc gattgggaag gagggatgag gatgccggac tccctcggcc agtgcagttg
1981 gatgagacac acccttacac ggtgacttcc gtgtcctgtt gccatggaaa caccctcctg
2041 gctgttcgat cggtcacaga tgagccggtc cccccctga
//