LOCUS AY263163 4746 bp mRNA linear HUM 30-JUN-2003
DEFINITION Homo sapiens TMC3 protein (TMC3) mRNA, complete cds.
ACCESSION AY263163
VERSION AY263163.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4746)
AUTHORS Keresztes,G., Mutai,H. and Heller,S.
TITLE TMC and EVER genes belong to a larger novel family, the TMC gene
family encoding transmembrane proteins
JOURNAL BMC Genomics 4 (1), 24 (2003)
PUBMED 12812529
REFERENCE 2 (bases 1 to 4746)
AUTHORS Keresztes,G., Mutai,H. and Heller,S.
TITLE Direct Submission
JOURNAL Submitted (26-MAR-2003) Department of Otolaryngology and Program in
Neuroscience, Massachusetts Eye and Ear Infirmary, Harvard Medical
School, Eaton-Peabody Laboratory, 243 Charles Street, Boston, MA
02114, USA
FEATURES Location/Qualifiers
source 1..4746
/db_xref="H-InvDB:HIT000251311"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="15"
/map="15q23"
gene 1..4746
/gene="TMC3"
CDS 43..3432
/gene="TMC3"
/codon_start=1
/product="TMC3 protein"
/protein_id="AAP78778.1"
/translation="MKTSKASQRYRGIRRNASQCYLYQESLLLNLDDSFSADETGDSN
DPEQIFQNIQFQKDLMANIRCRPWTMGQKLRALRQAKNIVLKFEGRLTRTRGYQAAGA
ELWRKFARLACNFVVIFIPWEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGA
FIVIPEVIAGQPFGSTARKTIPKEQVSSAQDLDTVWSLGGYLQYSVLFYGYYGRERKI
GRAGYRLPLAYFLVGMAVFAYSFIILLKRMAKNSRTSLASASNENYTFCWRVFCAWDY
LIGNPEAAESKTAAIVNSIREAILEEQEKKKSKNLAVTICLRIIANILVLLSLAGSIY
LIYFVVDRSQKLEQSKKELTLWEKNEVSVVVSLVTMIAPSAFDLIAALEMYHPRTTLR
FQLARVLVLYLGNLYSLIIALLDKVNSMSIEEMATKNNTSHWIDSTTFFATRTAPEEE
KWSTSRPGMGLRRNNTWALEETSISAYTMPLIKANKTSLHTQSPQDQCWETYVGQEML
KLSIIDMLFTVASILLIDFFRGLFVRYLSDYWCWDLESKFPEYGEFKIAENVLHLVYN
QGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAVLTCNVPHQQVFRASRSNNFYLAMLL
FMLFLCMLPTIFAIVRYKPSLNCGPFSGQEKIYDIVSETIEKDFPVWFGSVVGHISSP
VVILPAVLLLFMLIYYLQSIARSLKLSNHQLKMQIQNARSEDKKKVAQMVEGKXXXXX
XXXXXXXXXXXXXXXXXXXXXXAARIQTQEESTKKLPNDSDLTSQLSSAHSGTPQNNG
NVAHFDSGSSKSGRIETVAQSMPQSPRPGDRAPSSPLPGVPKSRLEHETNRYLHGLCA
STSDLHRNRSRTPMTFTTHIEDVHSEPLFRKDFQQINPPHRGPQASTLLAQGPRPHAP
RYYVINECDSYKKKHLNVWPERHFKIDASGDIVELYPRNVRQYASRVPRQPPSPQLSE
EEEETPSRDWIKRSLPPRSLIDLRRAPHFYIGERSESQTRDPEHQGRVHYKSWNEDFE
GHLERPAYVPRKPRSRNFQYPQPPLKPRGKPRFEPSLTESDSVSAASSSDQQNSSADQ
YLQVTHSQGRFPRSVGQPSRRKAKSGQELTVDLDDLICSDV"
BASE COUNT 1192 a 1196 c 1166 g 1111 t
ORIGIN
1 ctctctggcc agcttctgat tgttagcagt gggttagctc ccatgaaaac ctcgaaggca
61 tcccagcgct atagaggcat ccggagaaat gccagccagt gctacctcta ccaggaatct
121 ctgctgctca acttggatga cagctttagt gctgatgaaa caggggacag caatgatccg
181 gaacaaatct tccagaatat acagttccag aaagatctca tggcaaacat tcgctgcaga
241 ccctggacta tgggacagaa gctgagggca ttgaggcaag cgaagaacat tgtgctgaag
301 tttgaaggga ggctgaccag gacccgaggc taccaagcag caggtgcaga gctctggcgg
361 aaatttgctc gtctcgcctg taactttgtg gtcatcttca ttccctggga aatgaggata
421 aagaaaatcg agagtcattt tggatctggc gttgcctcct atttcatatt cttgagatgg
481 ttatttggaa ttaatattgt gctcaccatt atgacaggtg cttttattgt cattccagag
541 gtaattgcag gccagccctt tggaagcaca gccaggaaga ccatccccaa ggagcaggtt
601 tcgtctgccc aagacctgga caccgtctgg tctctggggg gctacctcca gtactctgtc
661 ctcttctacg gatattacgg cagggagagg aagatcggga gagctggcta ccggctgccc
721 ttggcgtatt tcctagtggg gatggcagtg tttgcttaca gcttcatcat tcttttaaaa
781 aggatggcta agaactcccg cacgagtctt gccagtgctt ccaatgaaaa ctataccttc
841 tgctggcggg tgttctgtgc ctgggattac ctcattggaa acccagaggc tgcagagagc
901 aaaacagctg ccatagtgaa cagcatcagg gaagctatat tggaagaaca ggagaaaaag
961 aaaagcaaaa acctggcagt gaccatctgc ctgaggatta ttgccaacat cctggtgctt
1021 ctctcactgg ctgggagcat ttatctcatc tactttgtgg tggaccggtc ccagaagctg
1081 gagcagtcga agaaggagct gacactttgg gaaaagaatg aggtcagtgt ggtggtctcc
1141 ctcgtcacca tgatagcacc atcagccttt gacctcattg ctgccttaga gatgtaccac
1201 cccaggacca cgctgcgctt ccagcttgca agggtccttg tgctgtattt gggaaatctc
1261 tacagcctga tcattgctct cctggacaaa gttaacagca tgagcattga ggaaatggct
1321 accaaaaata acacaagtca ttggatagat tccaccacct tctttgcaac caggacagcc
1381 cctgaagaag agaaatggtc cacatctcgg cctggaatgg ggctcaggag aaacaacaca
1441 tgggccttgg aagagaccag catttcagct tataccatgc ctcttataaa ggccaacaag
1501 actagcctcc acactcagag tccacaagac cagtgctggg agacatacgt tggtcaggag
1561 atgctgaagc tctccatcat tgacatgctc ttcaccgtgg cgagcattct gctcatagac
1621 ttcttccgag gacttttcgt gcggtactta agtgactact ggtgttggga tctggagagc
1681 aagtttcctg aatatggaga attcaaaata gctgagaatg tgctacattt agtctacaac
1741 caaggaatga tttggatggg ggccttcttc tccccatgtc tcccagcgtt caacgttctc
1801 aaactcattg ggctcatgta cctgagaagc tgggctgtgc tgacctgcaa tgtgccccac
1861 cagcaagtat ttcgagcctc aaggtccaac aacttctact tggcaatgct cctgtttatg
1921 ctgtttctgt gcatgctgcc aaccattttt gctattgtcc gatacaagcc atctctaaac
1981 tgtgggccat tcagtggaca agagaaaatt tatgacattg tgtcagaaac gattgagaaa
2041 gactttcctg tgtggtttgg ctccgtggtt ggacacatca gtagccccgt ggtcatcctg
2101 cccgcagtac tcctgctttt catgctcatc tattatctcc agagcatcgc acggtctcta
2161 aagctcagca accaccagct caaaatgcag atccaaaacg caagatcaga ggataagaaa
2221 aaggttgccc agatggtaga aggtaagnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
2281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnngc agcccgaatc
2341 cagacccagg aagaaagcac caagaagctt ccaaacgaca gtgatcttac cagccagctg
2401 tcctcagcgc actcgggcac accccaaaac aacggcaacg tggcccattt tgactcaggg
2461 agcagcaaga gtggcaggat agagacagtc gcacagtcca tgccccagag cccgaggcca
2521 ggggacaggg ctcctagctc acctctccct ggggtcccca aatccaggct agagcatgaa
2581 actaacaggt atctgcacgg tctgtgtgca agcaccagtg accttcacag gaacagatcg
2641 cgcacaccta tgacatttac aacgcacatc gaagatgtac actcagaacc tcttttccga
2701 aaagactttc agcaaatcaa ccctcctcac cgtggaccac aggcctcgac tttgctggca
2761 cagggtccca ggccccacgc ccccagatac tatgtcatta atgaatgtga ctcttacaag
2821 aaaaaacatc taaatgtctg gccagaaaga catttcaaga tagatgcttc aggtgacatt
2881 gtggagctgt accccaggaa cgtgcgacaa tatgcatccc gggtcccccg ccagcctccc
2941 tccccacagc tgagtgaaga agaggaggag acgccaagca gagattggat caaacggtct
3001 cttcccccac gctccctgat agacctccgt cgggctcctc atttttatat tggggagagg
3061 tccgaaagtc agacccggga tcccgagcac caggggaggg tgcactacaa gtcgtggaat
3121 gaagattttg agggtcacct tgagaggcca gcctatgtgc ccagaaagcc acgatcccgg
3181 aatttccaat acccacagcc ccctctgaag cccagaggga agcccaggtt cgagccatcc
3241 ctcacggaat ctgactccgt gtcggcagca tccagcagtg accagcagaa cagcagcgct
3301 gaccagtacc tgcaggtcac ccacagccag ggcaggttcc cgaggtccgt gggccagccc
3361 agcaggagga aggccaagtc ggggcaggag ctgaccgtgg atctggatga cttgatttgt
3421 tcagatgtct aggcttcctc cagtgtcccg ttcctagagg tcaggcccct gttggagtgc
3481 tgggccagca catggcatct ccctttctgg aaaaagaggt gaacaagtgt gttagagacc
3541 tgaggggcat ggtcagcggc tgctagctga ggccctgagg ctgacagggc tacagatacc
3601 tattctacag ctactgttag ccaaatttat ccgagttagg tggcaccaaa gtatgtcacc
3661 agcagtgaat catcacgggt ctgcagcaat ctcaatactt gcctcctcgg aagaaagaat
3721 ttggcagagg ggctcaagac agaaggagag actgaggcaa gttttagagc aggcatgaaa
3781 gtttactgaa aagctttaaa gcaggaatga aagaacgtaa aacatactta gtagagggcc
3841 aagcaggcga cttgagagat ccagtgcact gtttgacctt tgacttgggg ttttacacgt
3901 tggcatgctt ccggggtctt gcgttgcttc tccccacgat tcttcccttt cttcccttgg
3961 ggtgggctgt ccgcatgcgc agtagtggcc tgctagcgct ggggagggga gcatgcgcag
4021 tgtgtttact ggagttgtgc acgcgctcac tcgaggttct tcccttacca ggggaatgct
4081 ccattttgtc tcttagtgcg catgtttgag cccactcgcc caactcctga cattttatgg
4141 ggaagctgcc gatcaccagt ttcaggtttt ttctatctat tgggagactg tcgttccctg
4201 gtgccagctg tgaccaatta ttattttaga gagacaatca gcagccacct gaccatcacc
4261 tgatggtcgc ctgacattcc tgggggttgt gttgaagaag gaattcatga attttacaag
4321 tataatcaaa gacaaccaaa aatttttact ttttccttca aaagctaagt gtagtgtagc
4381 tcccccatag tctaagttaa agaagaacac taactgcctg tttttccttc tgtgctcagc
4441 aagccttatc tgtacttgct agtttcacat tccttgaggc tcagcgagtt cctgcttcac
4501 caccctagcg cagctgcaaa gttacaaggt tgatgcagaa acatggtttc ccagggatgt
4561 ggaacatgta gtatagataa atgtaaaaga ctgaacaact gcctttgctc tcgcttctgt
4621 aagtacgctt cctgcctcgc gtactcccgg ccaccgactg cttaaaaggt ggctgctttc
4681 tttatccagg gctcagactt tcctggacgc tagtcctact gagccaggtg atcacctttt
4741 aataaa
//