LOCUS AY253300 4896 bp mRNA linear HUM 21-FEB-2007
DEFINITION Homo sapiens IQGAP3 (IQGAP3) mRNA, complete cds.
ACCESSION AY253300
VERSION AY253300.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4896)
AUTHORS Wang,S., Watanabe,T., Noritake,J., Fukata,M., Yoshimura,T.,
Itoh,N., Harada,T., Nakagawa,M., Matsuura,Y., Arimura,N. and
Kaibuchi,K.
TITLE IQGAP3, a novel effector of Rac1 and Cdc42, regulates neurite
outgrowth
JOURNAL J. Cell. Sci. 120 (PT 4), 567-577 (2007)
PUBMED 17244649
REFERENCE 2 (bases 1 to 4896)
AUTHORS Fukata,M., Watanabe,T., Noritake,J. and Kaibuchi,K.
TITLE Direct Submission
JOURNAL Submitted (10-MAR-2003) Department of Cell Pharmacology, Nagoya
University, Graduate School of Medicine, 65 Tsurumai, Showa,
Nagoya, AICHI 466-8550, Japan
FEATURES Location/Qualifiers
source 1..4896
/db_xref="H-InvDB:HIT000251230"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="HEK293"
/cell_type="embryonic kidney"
gene 1..4896
/gene="IQGAP3"
CDS 1..4896
/gene="IQGAP3"
/codon_start=1
/product="IQGAP3"
/protein_id="AAP06954.1"
/translation="MERRAAGPGWAAYERLTAEEMDEQRRQNVAYQYLCRLEEAKRWM
EACLKEELPSPVELEESLRNGVLLAKLGHCFAPSVVPLKKIYDVEQLRYQATGLHFRH
TDNINFWLSAIAHIGLPSTFFPETTDIYDKKNMPRVVYCIHALSLFLFRLGLAPQIHD
LYGKVKFTAEELSNMASELAKYGLQLPAFSKIGGILANELSVDEAAVHAAVLAINEAV
ERGVVEDTLAALQNPSALLENLREPLAAVYQEMLAQAKMEKAANARNHDDRESQDIYD
HYLTQAEIQGNINHVNVHGALEVVDDALERQSPEALLKALQDPALALRGVRRDFADWY
LEQLNSDREQKAQELGLVELLEKEEVQAGVAAANTKGDQEQAMLHAVQRINKAIRRGV
AADTVKELMCPEAQLPPVYPVASSMYQLELAVLQQQQGELGQEELFVAVEMLSAVVLI
NRALEARDASGFWSSLVNPATGLAEVEGENAQRYFDALLKLRQERGMGEDFLSWNDLQ
ATVSQVNAQTQEETDRVLAVSLINEALDKGSPEKTLSALLLPAAGLDDVSLPVAPRYH
LLLVAAKRQKAQVTGDPGAVLWLEEIRQGVVRANQDTNTAQRMALGVAAINQAIKEGK
AAQTERVLRNPAVALRGVVPDCANGYQRALESAMAKKQCPADTAFWVQHDMKDGTAYY
FHLQTFQGIWEQPPGCPLNTSHLTREEIQSAVTKVTAAYDRQQLWKANVGFVIQLQAR
LRGFLVRQKFAEHSHFLRTWLPAVIKIQAHWRGYRQRKIYLEWLQYFKANLDAIIKIQ
AWARMWAARRQYLRRLHYFQKNVNSIVKIQAFFRARKAQDDYRILVHAPHPPLSVVRR
FAHLLNQSQQDFLAEAELLKLQEEVVRKIRSNQQLEQDLNIMDIKIGLLVKNRITLQE
VVSHCKKLTKRNKEQLSDMMVLDKQKGLKSLSKEKRQKLEAYQHLFYLLQTQPIYLAK
LIFQMPQNKTTKFMEAVIFSLYNYASSRREAYLLLQLFKTALQEEIKSKVEQPQDVVT
GNPTVVRLVVRFYRNGRGQSALQEILGKVIQDVLEDKVLSVHTDPVHLYKNWINQTEA
QTGQRSHLPYDVTPEQALSHPEVQRRLDIALRNLLAMTDKFLLAITSSVDQIPYGMRY
VAKVLKATLAEKFPDATDSEVYKVVGNLLYYRFLNPAVVAPDAFDIVAMAAGGALAAP
QRHALGAVAQLLQHAAAGKAFSGQSQHLRVLNDYLEETHLKFRKFIHRACQVPEPEER
FAVDEYSDMVAVAKPMVYITVGELVNTHRLLLEHQDCIAPDHQDPLHELLEDLGELPT
IPDLIGESIAADGHTDLSKLEVSLTLTNKFEGLEADADDSNTRSLLLSTKQLLADIIQ
FHPGDTLKEILSLSASREQEAAHKQLMSRRQACTAQTPEPLRRHRSLTAHSLLPLAEK
QRRVLRNLRRLEALGLVSARNGYQGLVDELAKDIRNQHRHRHRRKAELVKLQATLQGL
STKTTFYEEQGDYYSQYIRACLDHLAPDSKSSGKGKKQPSLHYTAAQLLEKGVLVEIE
DLPASHFRNVIFDITPGDEAGKFEVNAKFLGVDMERFQLHYQDLLQLQYEGVAVMKLF
NKAKVNVNLLIFLLNKKFLRK"
BASE COUNT 1178 a 1370 c 1398 g 950 t
ORIGIN
1 atggagagga gagcagcggg cccaggctgg gcagcctatg aacgcctcac agctgaggag
61 atggatgagc agaggcggca gaatgttgcc tatcagtacc tgtgccggct ggaggaggcc
121 aagcgctgga tggaggcctg cctgaaggag gagcttcctt ccccggtgga gctggaggag
181 agccttcgga atggagtgct gctggccaag ctgggccact gttttgcacc ctccgtggtt
241 ccgttgaaga agatctacga tgtggagcag ctgcggtacc aggcaactgg cttacatttc
301 cgtcacacag acaacatcaa cttttggcta tctgcaatag cccacatcgg tctgccttcg
361 accttcttcc cagagaccac ggacatctat gacaaaaaga acatgccccg ggtagtctac
421 tgcatccatg ctctcagtct cttcctcttc cggctgggat tggcccctca gatacatgat
481 ctatacggga aagtgaaatt cacagctgag gaactcagca acatggcgtc cgaactggcc
541 aaatatggcc tccagctgcc tgccttcagc aagatcgggg gcatcttggc caatgagctc
601 tcggtggatg aggctgcagt ccatgcagct gttcttgcca tcaatgaagc agtggagcga
661 ggggtggtgg aggacaccct ggctgccttg cagaatccca gtgctcttct ggagaatctc
721 cgagagcctc tggcagccgt ctaccaggag atgctggccc aggccaagat ggagaaggca
781 gccaatgcca ggaaccatga tgacagagaa agccaggaca tctatgacca ctacctaact
841 caggctgaaa tccagggcaa tatcaaccat gtcaacgtcc atggggctct agaagttgtt
901 gatgatgccc tggaaagaca gagccctgaa gccttgctca aggcccttca agaccctgcc
961 ctggccctgc gaggggtgag gagagacttt gctgactggt acctggagca gctgaactca
1021 gacagagagc agaaggcaca ggagctgggc ctggtggagc ttctggaaaa ggaggaagtc
1081 caggctggtg tggctgcagc caacacaaag ggtgatcagg aacaagccat gctccacgct
1141 gtgcagcgga tcaacaaagc catccggagg ggagtggcgg ctgacactgt gaaggagctg
1201 atgtgccctg aggcccagct gcctccagtg taccctgttg catcgtctat gtaccagctg
1261 gagctggcag tgctccagca gcagcagggg gagcttggcc aggaggagct cttcgtggct
1321 gtggagatgc tctcagctgt ggtcctgatt aaccgggccc tggaggcccg ggatgccagt
1381 ggcttctgga gcagcctggt gaaccctgcc acaggcctgg ctgaggtgga aggagaaaat
1441 gcccagcgtt acttcgatgc cctgctgaaa ttgcgacagg agcgtgggat gggtgaggac
1501 ttcctgagct ggaatgacct gcaggccacc gtgagccagg tcaatgcaca gacccaggaa
1561 gagactgacc gggtccttgc agtcagcctc atcaatgagg ctctggacaa aggcagccct
1621 gagaagactc tgtctgccct actgcttcct gcagctggcc tagatgatgt cagcctccct
1681 gtcgcccctc ggtaccatct cctccttgtg gcagccaaaa ggcagaaggc ccaggtgaca
1741 ggggatcctg gagctgtgct gtggcttgag gagatccgcc agggagtggt cagagccaac
1801 caggacacta atacagctca gagaatggct cttggtgtgg ctgccatcaa tcaagccatc
1861 aaggagggca aggcagccca gactgagcgg gtgttgagga accccgcagt ggcccttcga
1921 ggggtagttc ccgactgtgc caacggctac cagcgagccc tggaaagtgc catggcaaag
1981 aaacagtgtc cagcagacac agctttctgg gttcaacatg acatgaagga tggcactgcc
2041 tactacttcc atctgcagac cttccagggg atctgggagc aacctcctgg ctgccccctc
2101 aacacctctc acctgacccg ggaggagatc cagtcagctg tcaccaaggt cactgctgcc
2161 tatgaccgcc aacagctctg gaaagccaac gtcggctttg ttatccagct ccaggcccgc
2221 ctccgtggct tcctagttcg gcagaagttt gctgagcatt cccactttct gaggacctgg
2281 ctcccagcag tcatcaagat ccaggctcat tggcggggtt ataggcagcg gaagatttac
2341 ctggagtggt tgcagtattt taaagcaaac ctggatgcca taatcaagat ccaggcctgg
2401 gcccggatgt gggcagctcg gaggcaatac ctgaggcgtc tgcactactt ccagaagaat
2461 gttaactcca ttgtgaagat ccaggcattt ttccgagcca ggaaagccca agatgactac
2521 aggatattag tgcatgcacc ccaccctcct ctcagtgtgg tacgcagatt tgcccatctc
2581 ttgaatcaaa gccagcaaga cttcttggct gaggcagagc tgctgaagct ccaggaagag
2641 gtagttagga agatccgatc caatcagcag ctggagcagg acctcaacat catggacatc
2701 aagattggcc tgctggtgaa gaaccggatc actctgcagg aagtggtctc ccactgcaag
2761 aagctgacca agaggaataa ggaacagctg tcagatatga tggttctgga caagcagaag
2821 ggtttaaagt cgctgagcaa agagaaacgg cagaaactag aagcatacca acacctcttc
2881 tacctgctcc agactcagcc catctacctg gccaagctga tctttcagat gccacagaac
2941 aaaaccacca agttcatgga ggcagtgatt ttcagcctgt acaactatgc ctccagccgc
3001 cgagaggcct atctcctgct ccagctgttc aagacagcac tccaggagga aatcaagtca
3061 aaggtggagc agccccagga cgtggtgaca ggcaacccaa cagtggtgag gctggtggtg
3121 agattctacc gtaatgggcg gggacagagt gccctgcagg agattctggg caaggttatc
3181 caggatgtgc tagaagacaa agtgctcagc gtccacacag accctgtcca cctctataag
3241 aactggatca accagactga ggcccagaca gggcagcgca gccatctccc atatgatgtc
3301 accccggagc aggccttgag ccaccccgag gtccagagac gactggacat cgccctacgc
3361 aacctcctcg ccatgactga taagttcctt ttagccatca cctcatctgt ggaccaaatt
3421 ccgtatggga tgcgatatgt ggccaaagtc ctgaaggcaa ctctggcaga gaaattccct
3481 gacgccacag acagcgaggt ctataaggtg gtcgggaacc tcctgtacta ccgcttcctg
3541 aacccagctg tggtggctcc tgacgccttc gacattgtgg ccatggcagc tggtggagcc
3601 ctggctgccc cccagcgcca tgccctgggg gctgtggctc agctcctaca gcacgctgcg
3661 gctggcaagg ccttctctgg gcagagccag cacctacggg tcctgaatga ctatctggag
3721 gaaacacacc tcaagttcag gaagttcatc catagagcct gccaggtgcc agagccagag
3781 gagcgttttg cagtggacga gtactcagac atggtggctg tggccaaacc catggtgtac
3841 atcaccgtgg gggagctggt caacacgcac aggctgttgc tggagcacca ggactgcatt
3901 gcccctgatc accaagaccc cctgcatgag ctcctggagg atcttgggga gctgcccacc
3961 atccctgacc ttattggtga gagcatcgct gcagatgggc acacagacct gagcaagcta
4021 gaagtgtccc tgacgctgac caacaagttt gaaggactag aggcagatgc tgatgactcc
4081 aacacccgta gcctgcttct gagcaccaag cagctgttgg ccgatatcat acagttccat
4141 cctggggaca ccctcaagga gatcctgtcc ctctcggctt ccagagagca agaagcagcc
4201 cacaagcagc tgatgagccg acgccaggcc tgtacagccc agacaccgga gccactgcga
4261 cgacaccgct cactgacagc tcactccctc ctgccactgg cagagaagca gcggcgcgtc
4321 ctgcggaacc tgcgccgact tgaagccctg gggttggtca gcgccagaaa tggctaccag
4381 gggctagtgg acgagctggc caaggacatc cgcaaccagc acagacacag gcacaggcgg
4441 aaggcagagc tggtgaagct gcaggccaca ttacagggcc tgagcactaa gaccaccttc
4501 tatgaggagc agggtgacta ctacagccag tacatccggg cctgcctgga ccacctggcc
4561 cccgactcca agagttctgg gaaggggaag aagcagcctt ctcttcatta cactgctgct
4621 cagctcctgg aaaagggtgt cttggtggaa attgaagatc ttcccgcctc tcacttcaga
4681 aacgtcatct ttgacatcac gccgggagat gaggcaggaa agtttgaagt aaatgccaag
4741 ttcctgggtg tggacatgga gcgatttcag cttcactatc aggatctcct gcagctccag
4801 tatgagggtg tggctgtcat gaaactcttc aacaaggcca aagtcaatgt caaccttctc
4861 atcttcctcc tcaacaagaa gtttttgcgg aagtga
//