LOCUS AY238437 2871 bp mRNA linear HUM 02-FEB-2004
DEFINITION Homo sapiens inter-alpha trypsin inhibitor heavy chain precursor 5
(ITIH5) mRNA, complete cds.
ACCESSION AY238437
VERSION AY238437.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2871)
AUTHORS Himmelfarb,M., Klopocki,E., Grube,S., Staub,E., Klaman,I.,
Hinzmann,B., Kristiansen,G., Rosenthal,A., Durst,M. and Dahl,E.
TITLE ITIH5, a novel member of the inter-alpha-trypsin inhibitor heavy
chain family is downregulated in breast cancer
JOURNAL Cancer Lett. 204 (1), 69-77 (2004)
PUBMED 14744536
REFERENCE 2 (bases 1 to 2871)
AUTHORS Grube,S., Himmelfarb,M., Klopocki,E., Dahl,E. and Duerst,M.
TITLE Direct Submission
JOURNAL Submitted (18-FEB-2003) Department of Gynecology, Friedrich
Schiller University, Bachstr. 18, Jena 07740, Germany
FEATURES Location/Qualifiers
source 1..2871
/db_xref="H-InvDB:HIT000085441"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="10"
/map="10p14"
/tissue_type="mammary gland"
gene 1..2871
/gene="ITIH5"
CDS 3..2831
/gene="ITIH5"
/codon_start=1
/product="inter-alpha trypsin inhibitor heavy chain
precursor 5"
/protein_id="AAO49812.1"
/translation="MLLLLGLCLGLSLCVGSQEEAQSWGHSSEQDGLRVPRQVRLLQR
LKTKPLMTEFSVKSTIISRYAFTTVSCRMLNRASEDQDIEFQMQIPAAAFITNFTMLI
GDKVYQGEITEREKKSGDRVKEKRNKTTEENGEKGTEIFRASAVIPSKDKAAFFLSYE
ELLQRRLGKYEHSISVRPQQLSGRLSVDVNILESAGIASLEVLPLHNSRQRGSGRGED
DSGPPPSTVINQNETFANIIFKPTVVQQARIAQNGILGDFIIRYDVNREQSIGDIQVL
NGYFVHYFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSII
GFSNRIKVWKDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSG
IGDRSVSLIVFLTDGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKL
SLENCGLTRRVHEEEDAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFN
GSEIIIAGKLVDRKLDHLHVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDG
EGDPNHIERLWSYLTTKELLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLR
GPVPRMDGLEEAHGMSAAMGPEPVVQSVRGAGTQPGPLLKKPYQPRIKISKTSVDGDP
HFVVDFPLSRLTVCFNIDGQPGDILRLVSDHRDSGVTVNGELIGAPAPPNGHKKQRTY
LRTITILINKPERSYLEITPSRVILDGGDRLVLPCNQSVVVGSWGLEVSVSANANVTV
TIQGSIAFVILIHLYKKPAPFQRHHLGFYIANSEGLSSNCHGLLGQFLNQDARLTEDP
AGPSQNLTHPLLLQVGEGPEAVLTVKGHQVPVVWKQRKIYNGEEQIDCWFARNNAAKL
IDGEYKDYLASHPFDTGMTLGRGMSREL"
BASE COUNT 721 a 785 c 804 g 561 t
ORIGIN
1 ccatgctcct gctgctgggg ctgtgcctgg ggctgtccct gtgtgtgggg tcgcaggaag
61 aggcgcagag ctggggccac tcttcggagc aggatggact cagggtcccg aggcaagtca
121 gactgttgca gaggctgaaa accaaacctt tgatgacaga attctcagtg aagtctacca
181 tcatttcccg ttatgccttc actacggttt cctgcagaat gctgaacaga gcttctgaag
241 accaggacat tgagttccag atgcagattc cagctgcagc tttcatcacc aacttcacta
301 tgcttattgg agacaaggtg tatcagggcg aaattacaga gagagaaaag aagagtggtg
361 atagggtaaa agagaaaagg aataaaacca cagaagaaaa tggagagaag gggactgaaa
421 tattcagagc ttctgcagtg attcccagca aggacaaagc cgcctttttc ctgagttatg
481 aggagcttct gcagaggcgc ctgggcaagt acgagcacag catcagcgtg cggccccagc
541 agctgtccgg gaggctgagc gtggacgtga atatcctgga gagcgcgggc atcgcatccc
601 tggaggtgct gccgcttcac aacagcaggc agaggggcag tgggcgcggg gaagatgatt
661 ctgggcctcc cccatctact gtcattaacc aaaatgaaac atttgccaac ataattttta
721 aacctactgt agtacaacaa gccaggattg cccagaatgg aattttggga gactttatca
781 ttagatatga cgtcaataga gaacagagca ttggggacat ccaggttcta aatggctatt
841 ttgtgcacta ctttgctcct aaagaccttc ctcctttacc caagaatgtg gtattcgtgc
901 ttgacagcag tgcttctatg gtgggaacca aactccggca gaccaaggat gccctcttca
961 caattctcca tgacctccga ccccaggacc gtttcagtat cattggattt tccaaccgga
1021 tcaaagtatg gaaggaccac ttgatatcag tcactccaga cagcatcagg gatgggaaag
1081 tgtacattca ccatatgtca cccactggag gcacagacat caacggggcc ctgcagaggg
1141 ccatcaggct cctcaacaag tacgtggccc acagtggcat tggagaccgg agcgtgtccc
1201 tcatcgtctt cctgacggat gggaagccca cggtcgggga gacgcacacc ctcaagatcc
1261 tcaacaacac ccgagaggcc gcccgaggcc aagtctgcat cttcaccatt ggcatcggca
1321 acgacgtgga cttcaggctg ctggagaaac tgtcgctgga gaactgtggc ctcacacggc
1381 gcgtgcacga ggaggaggac gcaggctcgc agctcatcgg gttctacgat gaaatcagga
1441 ccccgctcct ctctgacatc cgcatcgatt atccccccag ctcagtggtg caggccacca
1501 agaccctgtt ccccaactac ttcaacggct cggagatcat cattgcgggg aagctggtgg
1561 acaggaagct ggatcacctg cacgtggagg tcaccgccag caacagtaag aaattcatca
1621 tcctgaagac agatgtgcct gtgcggcctc agaaggcagg gaaagatgtc acaggaagcc
1681 ccaggcctgg aggcgatgga gagggggacc ccaaccacat cgagcgtctc tggagctacc
1741 tcaccacaaa ggagctgctg agctcctggc tgcaaagtga cgatgaaccg gagaaggagc
1801 ggctgcggca gcgggcccag gccctggctg tgagctaccg cttcctcact cccttcacct
1861 ccatgaagct gagggggccg gtcccacgca tggacggcct ggaggaggcc cacggcatgt
1921 cggctgccat gggacccgaa ccggtggtgc agagcgtgcg aggagctggc acgcagccag
1981 gacctttgct caagaagcca taccagccaa gaattaaaat ctctaaaaca tcagtggatg
2041 gtgatcccca ctttgttgtg gatttccccc tgagcagact caccgtgtgc ttcaacattg
2101 atgggcagcc cggggacatc ctcaggctgg tctctgatca cagggactct ggtgtcacag
2161 tgaacggaga gttaattggg gcacccgccc ctccaaatgg ccacaagaaa cagcgcactt
2221 acttgcgcac tatcaccatc ctcatcaaca agccagagag atcttatctc gagatcacac
2281 cgagcagagt catcttggat ggtggggaca gactggtgct cccctgcaac cagagtgtgg
2341 tggtggggag ctgggggctg gaggtgtccg tgtctgccaa cgccaatgtc accgtcacca
2401 tccagggctc catagccttt gtcatcctca tccacctcta caaaaagccg gcgcccttcc
2461 agcgacacca cctgggtttc tacattgcca acagcgaggg cctttccagc aactgccacg
2521 gactgctggg tcagttcctg aatcaggatg ccagactcac agaagaccct gcagggccca
2581 gccagaacct cactcaccct ctgctccttc aggtgggaga ggggcctgag gccgtcctaa
2641 cagtgaaagg ccaccaagtc ccagtggtct ggaagcaaag gaagatttac aacggggaag
2701 agcagataga ctgctggttt gccaggaaca atgccgccaa actgattgac ggggagtaca
2761 aggattacct ggcatcccat ccatttgaca cagggatgac acttggccgg ggaatgtcca
2821 gggagctctg aagctggcag ccttaaagat gcaagtgcat gaaggacagt g
//