LOCUS AY217662 1337 bp mRNA linear HUM 15-MAR-2003
DEFINITION Homo sapiens putative RAS binding protein isoform A (RASSF5) mRNA,
complete cds; alternatively spliced.
ACCESSION AY217662
VERSION AY217662.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1337)
AUTHORS Burbee,D.G., White,M.A., Miller,D.S., Minna,J.D. and Muller,C.Y.
TITLE RASSF5 is transcriptionally inactivated by an epigenetic mechanism
in ovarian cancers
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1337)
AUTHORS Burbee,D.G., White,M.A., Miller,D.S., Minna,J.D. and Muller,C.Y.
TITLE Direct Submission
JOURNAL Submitted (13-JAN-2003) Hamon Center for Therapeutic Oncology
Research, University of Texas SW Medical Center, 5323 Harry Hines
Blvd., Dallas, TX 75390-8593, USA
FEATURES Location/Qualifiers
source 1..1337
/db_xref="H-InvDB:HIT000085327"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="12"
/map="12q14"
gene 1..1337
/gene="RASSF5"
CDS 121..837
/gene="RASSF5"
/note="encodes a peptide of 27.6 kDa with an amino
terminal domain similar to RASSF1C and RASS53C proteins;
contains a putative RAS binding protein and an acidic
coiled coil carboxyl terminal domain; putative tumor
suppressor; alternatively spliced"
/codon_start=1
/product="putative RAS binding protein isoform A"
/protein_id="AAO61687.1"
/translation="MSSGYSSLEEDAEDFFFTARTSFFRRAPQGKPRSGQQDVEKEKE
THSYLSKEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPPQTSPNSGKL
SPSSNGCMNTLHISSTNTVGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSD
REHPLYLRLVAGPRTDTLSFVLREHEIGEWEAFSLPELQNFLRILDKEEDEQLQNLKR
RYTAYRQKLEEALREVWKPD"
BASE COUNT 335 a 340 c 340 g 322 t
ORIGIN
1 gctgcataag gactgcccgg ggctgcgcgc cgggaacctc gcggggctgg cgggcgccgc
61 accccctccc tggccgcctg cgccccgggg aggccgcccg cgcgcgacgg gaccggcagc
121 atgagcagcg gctacagcag cctggaggag gacgccgagg acttcttctt caccgccagg
181 acctccttct tcaggagagc gccccagggc aagccccgct ccggccaaca agatgttgag
241 aaagagaagg aaacccacag ttacctcagc aaagaggaga tcaaagagaa agttcataaa
301 tacaacttag cagtcacaga caagttgaag atgaccttga attcaaatgg gatttacact
361 ggcttcatta aagtacagat ggaactctgc aaacctccac agacttctcc aaattctgga
421 aaactctctc ccagtagcaa tggctgtatg aatacacttc atatcagcag cacaaacact
481 gtcggggaag tgatcgaggc cctgctcaaa aagtttctcg tgactgagag ccctgccaag
541 tttgcacttt ataagcgttg tcacagggaa gaccaagtct acgcctgcaa gctctcagac
601 cgggaacatc cactctacct gcgtttggta gcagggccca gaacagacac acttagtttt
661 gttcttcgtg aacatgaaat tggagagtgg gaagccttca gccttccaga actacagaat
721 ttcttgcgca tcttggacaa ggaagaagat gaacagctgc agaacctgaa gaggcgctac
781 acagcctaca ggcagaagct ggaagaagcc ctccgtgagg tgtggaagcc tgattaaagc
841 ggggctccct gcccgtgagg cccggtgcag gaccgatgta caaaacagca gcaagtgcct
901 ctcttctcag agggctgctg tcttgcccca ctatgctagg gtcttcgcct ttctatctgt
961 agattttgtt ccccaaacct ggtcacacag catcctgcac cttagcgtcc catgtaaggg
1021 actctgcaag cttgttgttc agcaccgcag tgttacctct tggcaagctg tgaacctgtc
1081 gcctcatcag gagcattcga gggtgcttgg aagcatgaac tctgggggtg tttttttttt
1141 tggttatttt aattatgtga tgatgctgtt aagcttacag atatgcagtt gattttttaa
1201 aaagcttaac taggaatctt tctgaatact tgtcctattt tgaaactacc tgtctggttt
1261 tttgtttggt tttgttttct ttttttaatg tcagaggaat ctatccatgt gaatcgaaag
1321 gcacaggaat ctaggaa
//