LOCUS AY216268 1935 bp mRNA linear HUM 15-MAR-2003
DEFINITION Homo sapiens tumor suppressor RASSF3 isoform C mRNA, complete cds;
alternatively spliced.
ACCESSION AY216268
VERSION AY216268.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1935)
AUTHORS Burbee,D.G., White,M.A., Miller,D.S., Muller,C.Y. and Minna,J.D.
TITLE RASSF3 is regulated by methylation in lung and breast tumor cell
lines
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1935)
AUTHORS Burbee,D.G., White,M.A., Miller,D.S., Muller,C.Y. and Minna,J.D.
TITLE Direct Submission
JOURNAL Submitted (09-JAN-2003) Hamon Center for Therapeutic Oncology
Research, University of Texas SW Medical Center, 5323 Harry Hines
Blvd., Dallas, TX 75390-8593, USA
FEATURES Location/Qualifiers
source 1..1935
/db_xref="H-InvDB:HIT000085313"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q31-q32"
CDS 404..1201
/note="putative RAS binding protein; alternatively
spliced; similar to non-tumor suppressor RASSF1C, putative
tumor suppressor mouse Nore1 and rat Maxp1 gene products"
/codon_start=1
/product="tumor suppressor RASSF3 isoform C"
/protein_id="AAO61668.1"
/translation="MTVDSSMSSGYCSLDEELEDCFFTAKTTFFRNAQSKHLSKNVCK
PVEETQRPPTLQEIKQKIDSYNTREKNCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAG
IRPQSIYDAIKEVNLAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVD
NPQKFALFKRIHKDGQVLFQKLSIADRPLYLRLLAGPDTEVLSFVLKENETGEVEWDA
FSIPELQNFLTILEKEEQDKIQQVQKKYDKFRQKLEEALRESQGKPG"
BASE COUNT 459 a 541 c 539 g 396 t
ORIGIN
1 gctagtgaaa gtgcgcggga ggcgggggag gtgctgtgag atggcgcgtc tgcactggtc
61 ggcggtaggg aggtgctgct ggctgccgtg ggacacgaaa ccgcagagcc cggacgagtc
121 agggagtgag gcgcgagccg ggcgcccggg gctctgcagg cgcaggcggc gcggggacag
181 gagcaggtta ccgggccgcc cgagcgctcg caccccgctg aaagaaacgc aggcggcccg
241 ccggctctgc ctggtccgct acccgaccag ctcccggctc ggggctcaga gctaggggct
301 tacgccaagc ggagcccggg gaggggtgcc cacctccctc cgccgcatcc caagcccggc
361 ccccttgatg cgctggcggc ctcggccggg aactccgggg tagatgaccg tggacagcag
421 catgagcagt gggtactgca gcctggacga ggaactggaa gactgcttct tcactgctaa
481 gactaccttt ttcagaaatg cgcagagcaa acatctttca aagaatgtct gtaaacctgt
541 ggaggagaca cagcgcccgc ccacactgca ggagatcaag cagaagatcg acagctacaa
601 cacgcgagag aagaactgcc tgggcatgaa actgagtgaa gacggcacct acacgggttt
661 catcaaagtg catctgaaac tccggcggcc tgtgacggtg cctgctggga tccggcccca
721 gtccatctat gatgccatca aggaggtgaa cctggcggct accacggaca agcggacatc
781 cttctacctg cccctagatg ccatcaagca gctgcacatc agcagcacca ccaccgtcag
841 tgaggtcatc caggggctgc tcaagaagtt catggttgtg gacaatcccc agaagtttgc
901 actttttaag cggatacaca aggacggaca agtgctcttc cagaaactct ccattgctga
961 ccgccccctc tacctgcgcc tgcttgctgg gcctgacacg gaggtcctca gctttgtgct
1021 aaaggagaat gaaactggag aggtagagtg ggatgccttc tccatccctg aacttcagaa
1081 cttcctaaca atcctggaaa aagaggagca ggacaaaatc caacaagtgc aaaagaagta
1141 tgacaagttt aggcagaaac tggaggaggc cttaagagaa tcccagggca aacctgggta
1201 accggtcctg cttcctctcc tcctggtgca ttcagattta tttgtattat taattattat
1261 tttgcaacag acactttttc tcaggacatc tctggcaggt gcatttgtgc ctgcccagca
1321 gttccagctg tggcaaaagt ctcttccatg gacaagtgtt tgcacggggg ttcagctgtg
1381 cccgccccca ggctgtgccc caccacagat tctgccaagg atcagaactc atgtgaaaca
1441 aacagctgac gtcctctctc gatctgcaag cctttcacca accaaatagt tgcctctctc
1501 gtcaccaaac tggaacctca caccagccgg caaaggaagg aagaaaggtt ttagagctgt
1561 gtgttctttc tctggctttg attcttcttt gagttctctt acttgccacg tacaggacca
1621 ttatttatga gtgaaaagtt gtagcacatt ccttttgcag gtctgagcta agcccctgaa
1681 agcagggtaa tgctcataaa aggactgttc ccgcggcccc aaggtgcctg ttgttcacac
1741 ttaagggaag tttataaagc tactggcccc agatgctcag ggtaaggagc accaaagctg
1801 aggctggctc agagatctcc agagaagctg cagcctgccc tggccctggc tctggccctg
1861 gcccacattg cacatggaaa cccaaaggca tatatctgcg tatgtgtggt acttagtcac
1921 atctttgtca acaaa
//