LOCUS AY198414 5165 bp mRNA linear HUM 11-AUG-2003
DEFINITION Homo sapiens PR domain-containing protein 1 alpha (PRDM1) mRNA,
complete cds.
ACCESSION AY198414
VERSION AY198414.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5165)
AUTHORS Gyory,I., Fejer,G., Ghosh,N., Seto,E. and Wright,K.L.
TITLE Identification of a functionally impaired positive regulatory
domain I binding factor 1 transcription repressor in myeloma cell
lines
JOURNAL J. Immunol. 170 (6), 3125-3133 (2003)
PUBMED 12626569
REFERENCE 2 (bases 1 to 5165)
AUTHORS Gyory,I. and Wright,K.L.
TITLE Direct Submission
JOURNAL Submitted (17-DEC-2002) Department of Interdisciplinary Oncology,
H. Lee Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL
33612, USA
FEATURES Location/Qualifiers
source 1..5165
/db_xref="H-InvDB:HIT000085222"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="6"
/map="6q21-q22.1"
gene 1..5165
/gene="PRDM1"
CDS 343..2712
/gene="PRDM1"
/note="PRDI-BF1 alpha; contains ZNF domain; similar to
mouse Blimp-1"
/codon_start=1
/product="PR domain-containing protein 1 alpha"
/protein_id="AAO45623.1"
/translation="MKMDMEDADMTLWTEAEFEEKCTYIVNDHPWDSGADGGTSVQAE
ASLPRNLLFKYATNSEEVIGVMSKEYIPKGTRFGPLIGEIYTNDTVPKNANRKYFWRI
YSRGELHHFIDGFNEEKSNWMRYVNPAHSPREQNLAACQNGMNIYFYTIKPIPANQEL
LVWYCRDFAERLHYPYPGELTMMNLTQTQSSLKQPSTEKNELCPKNVPKREYSVKEIL
KLDSNPSKGKDLYRSNISPLTSEKDLDDFRRRGSPEMPFYPRVVYPIRAPLPEDFLKA
SLAYGIERPTYITRSPIPSSTTPSPSARSSPDQSLKSSSPHSSPGNTVSPVGPGSQEH
RDSYAYLNASYGTEGLGSYPGYAPLPHLPPAFIPSYNAHYPKFLLPPYGMNCNGLSAV
SSMNGINNFGLFPRLCPVYSNLLGGGSLPHPMLNPTSLPSSLPSDGARRLLQPEHPRE
VLVPAPHSAFSFTGAAASMKDKACSPTSGSPTAGTAATAEHVVQPKATSAAMAAPSSD
EAMNLIKNKRNMTGYKTLPYPLKKQNGKIKYECNVCAKTFGQLSNLKVHLRVHSGERP
FKCQTCNKGFTQLAHLQKHYLVHTGEKPHECQVCHKRFSSTSNLKTHLRLHSGEKPYQ
CKVCPAKFTQFVHLKLHKRLHTRERPHKCSQCHKNYIHLCSLKVHLKGNCAAAPAPGL
PLEDLTRINEEIEKFDISDNADRLEDVEDDISVISVVEKEILAVVRKEKEETGLKVSL
QRNMGNGLLSSGCSLYESSDLPLMKLPPSNPLPLVPVKVKQETVEPMDP"
BASE COUNT 1456 a 1254 c 1105 g 1350 t
ORIGIN
1 gggaagccag acggttaaca cagacaaagt gctgccgtga cactcggccc tccagtgttg
61 cggagaggca agagcagcga ccgcggcacc tgtccgcccg gagctgggac gcgggcgccc
121 gggcggccgg acgaagcgag gagggaccgc cgaggtgcgc gtctgtgcgg ctcagcctgg
181 cgggggacgc ggggagaatg tggactgggt agagatgaac gagacttttc tcagatgttg
241 gatatttgct tggaaaaacg tgtgggtacg accttggctg cccccaagtg taactccagc
301 actgtgaggt ttcagggatt ggcagagggg accaagggga ccatgaaaat ggacatggag
361 gatgcggata tgactctgtg gacagaggct gagtttgaag agaagtgtac atacattgtg
421 aacgaccacc cctgggattc tggtgctgat ggcggtactt cggttcaggc ggaggcatcc
481 ttaccaagga atctgctttt caagtatgcc accaacagtg aagaggttat tggagtgatg
541 agtaaagaat acataccaaa gggcacacgt tttggacccc taataggtga aatctacacc
601 aatgacacag ttcctaagaa cgccaacagg aaatattttt ggaggatcta ttccagaggg
661 gagcttcacc acttcattga cggctttaat gaagagaaaa gcaactggat gcgctatgtg
721 aatccagcac actctccccg ggagcaaaac ctggctgcgt gtcagaacgg gatgaacatc
781 tacttctaca ccattaagcc catccctgcc aaccaggaac ttcttgtgtg gtattgtcgg
841 gactttgcag aaaggcttca ctacccttat cccggagagc tgacaatgat gaatctcaca
901 caaacacaga gcagtctaaa gcaaccgagc actgagaaaa atgaactctg cccaaagaat
961 gtcccaaaga gagagtacag cgtgaaagaa atcctaaaat tggactccaa cccctccaaa
1021 ggaaaggacc tctaccgttc taacatttca cccctcacat cagaaaagga cctcgatgac
1081 tttagaagac gtgggagccc cgaaatgccc ttctaccctc gggtcgttta ccccatccgg
1141 gcccctctgc cagaagactt tttgaaagct tccctggcct acgggatcga gagacccacg
1201 tacatcactc gctcccccat tccatcctcc accactccaa gcccctctgc aagaagcagc
1261 cccgaccaaa gcctcaagag ctccagccct cacagcagcc ctgggaatac ggtgtcccct
1321 gtgggccccg gctctcaaga gcaccgggac tcctacgctt acttgaacgc gtcctacggc
1381 acggaaggtt tgggctccta ccctggctac gcacccctgc cccacctccc gccagctttc
1441 atcccctcgt acaacgctca ctaccccaag ttcctcttgc ccccctacgg catgaattgt
1501 aatggcctga gcgctgtgag cagcatgaat ggcatcaaca actttggcct cttcccgagg
1561 ctgtgccctg tctacagcaa tctcctcggt gggggcagcc tgccccaccc catgctcaac
1621 cccacttctc tcccgagctc gctgccctca gatggagccc ggaggttgct ccagccggag
1681 catcccaggg aggtgcttgt cccggcgccc cacagtgcct tctcctttac cggggccgcc
1741 gccagcatga aggacaaggc ctgtagcccc acaagcgggt ctcccacggc gggaacagcc
1801 gccacggcag aacatgtggt gcagcccaaa gctacctcag cagcgatggc agcccccagc
1861 agcgacgaag ccatgaatct cattaaaaac aaaagaaaca tgaccggcta caagaccctt
1921 ccctacccgc tgaagaagca gaacggcaag atcaagtacg aatgcaacgt ttgcgccaag
1981 actttcggcc agctctccaa tctgaaggtc cacctgagag tgcacagtgg agaacggcct
2041 ttcaaatgtc agacttgcaa caagggcttt actcagctcg cccacctgca gaaacactac
2101 ctggtacaca cgggagaaaa gccacatgaa tgccaggtct gccacaagag atttagcagc
2161 accagcaatc tcaagaccca cctgcgactc cattctggag agaaaccata ccaatgcaag
2221 gtgtgccctg ccaagttcac ccagtttgtg cacctgaaac tgcacaagcg tctgcacacc
2281 cgggagcggc cccacaagtg ctcccagtgc cacaagaact acatccatct ctgtagcctc
2341 aaggttcacc tgaaagggaa ctgcgctgcg gccccggcgc ctgggctgcc cttggaagat
2401 ctgacccgaa tcaatgaaga aatcgagaag tttgacatca gtgacaatgc tgaccggctc
2461 gaggacgtgg aggatgacat cagtgtgatc tctgtagtgg agaaggaaat tctggccgtg
2521 gtcagaaaag agaaagaaga aactggcctg aaagtgtctt tgcaaagaaa catggggaat
2581 ggactcctct cctcagggtg cagcctttat gagtcatcag atctacccct catgaagttg
2641 cctcccagca acccactacc tctggtacct gtaaaggtca aacaagaaac agttgaacca
2701 atggatcctt aagattttca gaaaacactt attttgtttc ttaagttatg acttggtgag
2761 tcagggtgcc tgtaggaagt ggcttgtaca taatcccagc tctgcaaagc tctctcgaca
2821 gcaaatggtt tcccctcacc tctggaatta aagaaggaac tccaaagtta ctgaaatctc
2881 agggcatgaa caaggcaaag gccatatata tatatatata tatatctgta tacatattat
2941 atatacttat ttacacctgt gtctatatat ttgcccctgt gtattttgaa tatttgtgtg
3001 gacatgtttg catagccttc ccattactaa gactattacc tagtcataat tattttttca
3061 atgataatcc ttcataattt attatacaat ttatcattca gaaagcaata attaaaaaag
3121 tttacaatga ctggaaagat tccttgtaat ttgagtataa atgtattttt gtcttgtggc
3181 cattctttgt agataatttc tgcacatctg tataagtacc taagatttag ttaaacaaat
3241 atatgacttc agtcaacctc tctctctaat aatggtttga aaatgaggtt tgggtaattg
3301 ccaatgttgg acagttgatg tgttcattcc tgggatccta tcatttgaac agcattgtac
3361 ataacttggg ggtatgtgtg caggattacc caagaataac ttaagtagaa gaaacaagaa
3421 agggaatctt gtatattttt gttgatagtt catgtttttc ccccagccac aattttaccg
3481 gaagggtgac aggaaggctt taccaacctg tctctccctc caaaagagca gaatcctccc
3541 accgccctgc cctccccacc gagtcctgtg gccattcaga gcggccacat gacttttgca
3601 tccattgtat tatcagaaaa tgtgaagaag aaaaaaatgc catgttttaa aaccactgcg
3661 aaaatttccc caaagcatag gtggctttgt gtgtgtgcga tttgggggct tgagtctggg
3721 tggtgttttg ttgttggttt ttgttgcttt tttttttttt ttttttttaa tgtcaaaatt
3781 gcacaaacat ggtgctctac caggaaggat tcgaggtaga taggctcagg ccacacttta
3841 aaaacaaaca cacaaacaac aaaaaacggg tattctagtc atcttggggt aaaagcgggt
3901 aatgaacatt cctatcccca acacatcaat tgtatttttt ctgtaaaact cagattttcc
3961 tcagtatttg tgtttttaca ttttatggtt aatttaatgg aagatgaaag ggcattgcaa
4021 agttgttcaa caacagttac ctcattgagt gtgtccagta gtgcaggaaa tgatgtctta
4081 tctaatgatt tgcttctcta gaggagaaac cgagtaaatg tgctccagca agatagactt
4141 tgtgttattc tatcttttat tctgctaagc ccaaagatta catgttggtg ttcaaagtgt
4201 agcaaaaaat gatgtatatt tataaatcta tttataccac tatatcatat gtatatatat
4261 ttataaccac ttaaattgtg agccaagcca tgtaaaagat ctactttttc taagggcaaa
4321 aaaaaaaaaa aaaaaaaaag aacactcctt tctgagactt tgcttaatac ttggtgacct
4381 cacaatcacg tcggtatgat tgggcaccct tgcctactgt aagagaccct aaaaccttgg
4441 tgcagtggtg gggaccacaa aacaaccagg gaggaagaga tacatcattt tttagtatta
4501 aggaccatct aagacagctc tatttttttt ttgccacttt atgattatgt ggtcacaccc
4561 aagtcacaga aataaaaaac tgactttacc gctgcaattt ttctgttttc ctccttacta
4621 aatactgata cattactcca atctatttta taattatatt tgacattttg ttcacatcaa
4681 ctaatgttca cctgtagaag agaacaaatt tcgaataatc cagggaaacc caagagcctt
4741 actggtcttc tgtaacttcc aagactgaca gctttttatg tatcagtgtt tgataaacac
4801 agtccttaac tgaaggtaaa ccaaagcatc acgttgacat tagaccaaat acttttgatt
4861 cccaactact cgtttgttct ttttctcctt ttgtgctttc ccatagtgag aatttttata
4921 aagacttctt gcttctctca ccatccatcc ttctcttttc tgcctcttac atgtgaatgt
4981 tgagcccaca atcaacagtg gttttatttt ttcctctact caaagttaaa actgaccaaa
5041 gttactggct ttttactttg ctagaacaac aaactatctt atgtttacat actggtttac
5101 aatgttattt atgtgcaaat tgtcaaaatg taaattaaat ataaatgttc atgctttacc
5161 aaaat
//