LOCUS AY191814 4296 bp mRNA linear HUM 01-JAN-2004
DEFINITION Homo sapiens protein tyrosine phosphatase-like member b (PTPLB)
mRNA, complete cds.
ACCESSION AY191814
VERSION AY191814.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4296)
AUTHORS Wang,B. and Shore,G.C.
TITLE Novel ER-associated degradation protein PTPLB functionally
associated with BAP31 identified through a novel split-ubiquitin
membrane protein two-hybrid processor
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 4296)
AUTHORS Wang,B. and Shore,G.C.
TITLE Direct Submission
JOURNAL Submitted (06-DEC-2002) Biochemistry, McGill University, 3655
Promenade Sir William Osler, Montreal, Quebec H3G 1Y6, Canada
FEATURES Location/Qualifiers
source 1..4296
/db_xref="H-InvDB:HIT000250953"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
gene 1..4296
/gene="PTPLB"
CDS 163..927
/gene="PTPLB"
/note="BAP31-associated ER degradation protein; cooperates
with BAP31p20 to induce apopotosis"
/codon_start=1
/product="protein tyrosine phosphatase-like member b"
/protein_id="AAP20101.1"
/translation="MAAVAATAAAKGNGGGGGRAGAGDASGTRKKKGPGPLATAYLVI
YNVVMTAGWLVIAVGLVRAYLAKGSYHSLYYSIEKPLKFFQTGALLEILHCAIGIVPS
SVVLTSFQVMSRVFLIWAVTHSVKEVQSEDSVLLFVIAWTITEIIRYSFYTFSLLNHL
PYLIKWARYTLFIVLYPMGVSGELLTIYAALPFVRQAGLYSISLPNKYNFSFDYYAFL
ILIMISYIPIFPQLYFHMIHQRRKILSHTEEHKKFE"
BASE COUNT 1218 a 877 c 857 g 1344 t
ORIGIN
1 ggggctttgc cctcagccaa gatggcggct gccgtggacc ctgtcccggc tccgccccgc
61 ggccctggcc ccgcctgccc ctcgtccctt cctccgcccc ctctcctcgc gtagtccggc
121 ccgagccgct cgcgctagga gagcgggctt cgggcacttg acatggcggc agtggcggcg
181 actgcagcag cgaaggggaa tgggggcggc ggtggcaggg ccggggccgg ggacgccagc
241 ggcacgcgga agaagaaggg cccggggccc ctggccacgg cgtacctggt catctacaat
301 gtggtgatga cagccgggtg gctggttata gcggttggtc tggtccgagc atacctggct
361 aagggtagct accatagcct ttattattca attgaaaagc ctttgaaatt ctttcaaact
421 ggagccttat tggagatttt acattgtgct ataggaattg ttccatcttc tgttgtcctg
481 acttctttcc aggtgatgtc aagagttttt ctaatatggg cagtaacaca tagcgtcaaa
541 gaggtacaga gtgaagacag tgtcctcctg tttgttattg catggacgat cacggaaatc
601 atccgttact ccttttatac attcagtcta ttaaaccatc tgccttacct catcaaatgg
661 gccaggtaca cacttttcat tgtgctgtac ccaatgggag tgtcaggaga actgctcaca
721 atatatgcag ctctgccctt tgtcagacaa gctggcctat attccatcag tttacccaac
781 aaatacaatt tctcttttga ctactatgca ttcctgattc taataatgat ctcctacatt
841 ccaatttttc cccagttata cttccacatg atacaccaga gaagaaagat cctttctcat
901 actgaagaac acaagaaatt tgaatagttc ctgctttctg cacctcccac caaaacaaac
961 ttttcaatga tcaaaaaatg ctgcagattt tttgagttcc caatacgttt catagaaaat
1021 aagtaagaac tatttttaaa atattcaaac aaaactaaaa caaaaatcca gtgtcacatg
1081 ggcctgagat tttattttag aaaaaggttg ttacataaaa caccctggcc agttcatttc
1141 agcatgctct ttcaaccaga agttcttaat atttatgatg gcactagaaa gggatttggc
1201 attttatgtc cttctgtgtc cttcatgtat ctgatcaatg aagacctgta acactaagta
1261 cttgagagtt acagtctgaa taatgaagtc gtaccagctg aatagcccag cttgcagtat
1321 agttatgttt cagtctgcag tgtgtttagc attcccttgt caaagtgctt gactgcatgc
1381 tggaaacttt gtatttttga agcggcaaac tctgttctct ggaatgctct gaagttatgg
1441 ctgggaccta tcccctcaca tctaatgaat gaattataaa atgtatatgt ctatgaagct
1501 tcggggtagt gcctgtaatc agaaaacaac ttagaaccct tttgtttgtt tccaattgag
1561 tcattactgc ctgccactaa gaaacgtgct tgaatctaat aagtatgtgt gtaccgtaaa
1621 gaatatatct tatctggagc tcagcctcaa tcatgtctta acaaaatgac aggtctcaga
1681 aagggggagc tcaatagctc aaaagtgaca agtccttttc acagcaccat tctcagaaca
1741 cctctgagta acgtgtttgc cagtagctat tctcactgat gcactgatgg ccctgaagaa
1801 gcggatccag tcacatagga aaggaggctg tgttagtgaa agcacatgga aggtgttgct
1861 ttagaaaggt agtcaggaaa aacattcagg aatagattta tacaccatta ttgttttatt
1921 tttaaatttt cattcactct tctgtttgga tacttttgct aattaacttc ctatgttaat
1981 ttccaccaag ctataagtcc atagtcagta aaacattccc cttgggctgt catgagctaa
2041 aagcagtgtc atctccgcat gttggagcag ccaagaaata gtttggtact accgacattg
2101 tctaatccat gtcacatcct catacaattt aattgctcaa ccatgcattt aaaactcctc
2161 aagaaaggat tggtactgca actgtaggta aactgaaaaa aaataagaaa gaaagagttg
2221 gatgaaaatg tgaaagccca agtttagatg tgcattaagt attaaatagc acagtatctt
2281 cttcatggag ccttttttcc tcccccatcc cctgcagctg cctttttttg ggggcagggt
2341 gggggttgat gttgaacttt aagagtttaa aagtttagct tattgagtag ttgtcattta
2401 aaatataatt gcgaatatca gaaaactcat actggaaaac taaatttttt ttttctcttg
2461 agacggagtc tcgctctgtt gcccaggctg gagtgcagtg gcgcgatctc agctcactgc
2521 aagctccacc tcccgggttc acgccatcct cctgcctcag cctcctgagt agctgggact
2581 acaggtgcct gccaccacac ccagctaatt ttttttgtat ttttagtaga gacggggttt
2641 caccgtgtta gccaggatgg tcttgatctc ctgacctcgt gatccacccg cctcagcctc
2701 ccaaagtgct gggattgcag gcatgagcca ctgcacccaa cccctggaaa actaaatttt
2761 taagtgctta tttttataga agtttgaaaa tttaatgcag gcaggtgtgt aataaattat
2821 ttttgaattg aacattaaaa ttctgcttct taaagtcagc actcaacttg gacatgttga
2881 aattagaatc tattcttgta tttgatagac aaaatatgtg ggaaagattt tttgcatgac
2941 ttttctctca ttttattctt ccataatgta tttctactat aaaatagaat caacttgggt
3001 tatatttgtc atttactttg ttctgttaga ttttttcagt tgtttttgga aaaattctag
3061 aaatcaggat gaaaaatgca gcttttccag ggttgctgga ctgggggttt tatttgggcc
3121 tccttattat aatttgtcac tacttataaa aaacattctg ttgcaaacag tggtgttgca
3181 ttgaattgaa ctttggcaat gagaacacag cacacagctc ccttttcaaa aagggtctca
3241 accccagtgt gtatttttgt acatcaacat ttagaatact tatggcagat aagtaaggca
3301 tgtcactgtg tccttcagta acctctctca gtaactggtt tctttatccc taacatgaat
3361 tcatttctcc tttgaagtca tttattattt tataaattga gaacaaccac accaccaaat
3421 gtcacacctt cttataaagt gtgaacaagg aaggtcatgt ttttgtgggt attttgtcag
3481 acttagaggt ttcatttcag ggcatagtca aaggcatcat cctcccaact acccacttga
3541 ttatgtattt cagatccctc cgtgggggcc ttcttctgac agagaattct ttgaggtccg
3601 cagtagtgct tttgtcagca cagactgcta atctacatct tgctgcgttc tgtttgctga
3661 ggttgggctt attcatttaa cacataccaa ccattatcca gaggcaccat ggagagttag
3721 tcatggaata aagcactgtc cttgcagatg aaaaaagtct ccagagcaga cttctgacag
3781 gaaaggttta gatgctggag agttgaagag gtgtaagaag agatcgtgcc ctcatttttc
3841 acttattttt ttggttattc atttataata aaaggttggc attgatatgg tacaacctgc
3901 aaattacttg cagttctgag tttcagataa aacattataa aacattaaat tcaatacata
3961 ctgctccttt gaaatttggg taaaaaattg tacaaccgta tatatagtca tttttgtatt
4021 ttttctatgt tgtgaaaacc aaaattgtaa ttttataagt ctttgattca ctaaaattat
4081 ataatttaaa tgtatttttt gtatatttag aaataaggag tccagagact acgcttaact
4141 ttctatgcat gcatttgaaa gctgttttta cctgataatg tagtaataag ttgtattcat
4201 aaaatactga tctgtgttgc atttcaaaat aaactggtgt gtgctctgcc tggatttgaa
4261 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//