LOCUS AY177785 1971 bp mRNA linear HUM 24-JUN-2005
DEFINITION Homo sapiens copine VIII (CPEVIII) mRNA, complete cds.
ACCESSION AY177785
VERSION AY177785.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1971)
AUTHORS Ramsey,H., Zhang,D.E., Richkind,K., Burcoglu-O'Ral,A. and Hromas,R.
TITLE Fusion of AML1/Runx1 to copine VIII, a novel member of the copine
family, in an aggressive acute myelogenous leukemia with t(12;21)
translocation
JOURNAL Leukemia 17 (8), 1665-1666 (2003)
PUBMED 12886257
REFERENCE 2 (bases 1 to 1971)
AUTHORS Hromas,R.A., Ramsey,H. and Richkind,K.
TITLE Direct Submission
JOURNAL Submitted (11-NOV-2002) Medicine, Indiana University, R4-202, 1044
W. Walnut St., Indianapolis, IN 46202, USA
FEATURES Location/Qualifiers
source 1..1971
/db_xref="H-InvDB:HIT000084993"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="12"
/map="12q12"
gene 1..1971
/gene="CPEVIII"
CDS 1..1695
/gene="CPEVIII"
/note="calcium-binding protein that regulates cell growth;
contains two amino terminal C2 domains and carboxy
terminal VWF domain"
/codon_start=1
/product="copine VIII"
/protein_id="AAO21123.1"
/translation="MDSRYNSTAGIGDLNQLSAAIPATRVEVSVSCRNLLDRDTFSKS
DPICVLYVQGVGNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERENLRFDLYDVDS
KSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIVGIPGKKCGTIILTAEELNCCRDAV
LMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVR
ALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELSRGQSQFNVYEVVNPKKKGKK
KKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNP
YQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDG
IEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGIISDMA
QTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRD
YIDRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIKPSPAPPPYTPPTHVLQTQI"
BASE COUNT 607 a 361 c 428 g 575 t
ORIGIN
1 atggacagcc gctacaacag cactgcgggc atcggggact tgaaccagct gagcgctgcc
61 atcccggcca cgcgggtgga ggtgtccgtg tcctgcagaa atcttcttga cagagacaca
121 ttttctaaat ctgatccaat ttgtgtctta tatgtacaag gagttggaaa taaagaatgg
181 agagagtttg gaagaactga agtaattgat aatactttaa atcctgattt tgtaagaaag
241 tttattctgg actacttttt tgaagaaaga gagaatcttc gttttgactt gtatgatgtt
301 gattcaaaga gccccaactt atccaaacat gactttctgg gacaagtgtt ttgtacattg
361 ggagagatcg ttggttcaca gggaagtcgc ctggaaaaac caatagtagg aattccaggg
421 aagaaatgtg gtacaatcat acttacagca gaggaattaa actgttgcag ggatgccgtt
481 ttgatgcaat tttgtgcgaa caaattggac aagaaggact tctttggaaa atcagatcct
541 ttccttgtat tttatcgaag taatgaagat ggcagtttta caatttgtca caagacagaa
601 gttgtcaaaa acactctaaa tccagtatgg caagcattca agatctcagt cagagcatta
661 tgtaatggag actatgacag aacaatcaaa gtagaggtgt atgactggga ccgagatgga
721 agtcatgatt tcattggaga atttacaaca agctataggg aactttctag agggcagtca
781 caattcaacg tatatgaggt ggtgaatccc aaaaagaaag gaaaaaagaa aaaatatact
841 aattctggaa cagtaacttt actctctttc ttggtagaaa cagaagtttc attccttgac
901 tacattaagg gagggacgca aatcaatttc acagtggcta ttgattttac agcatcaaac
961 ggcaaccctg ctcagcccac ttccctccac tacatgaatc cttaccaact gaacgcctat
1021 ggtatggcac taaaagcagt gggagaaatt gttcaagatt atgacagtga taaaatgttt
1081 ccagctctag gatttggtgc aaaactgcct ccagatggaa ggatatctca cgaatttgct
1141 ttgaatggga atcctcaaaa cccctactgt gatggcattg agggggtcat ggaggcttat
1201 tacaggagtc tgaaatctgt acaactatat gggcccacca actttgctcc tgtaattaat
1261 catgtagcaa gatatgcttc ttctgtaaag gatggctccc agtattttgt gcttctgatt
1321 gttacagatg gtattatctc agatatggcc cagactaagg agtccatagt taatgcctca
1381 aaacttccaa tgtcaataat tatagtaggt gttggaccag cagaatttga tgcaatggtc
1441 gaattggatg gagatgatgt aagagtctcc tctagaggaa aatatgctga aagagacatt
1501 gtgcagtttg tgccattcag ggattatatt gacagaagtg gaaaccacat actgagcatg
1561 gctagattgg ctaaagatgt cctagctgag atccctgagc agtttctctc ctatatgaga
1621 gcccgaggaa tcaagccatc acctgcgcct cccccataca ccccacctac acatgtgtta
1681 cagactcaaa tatgactgtg ctctgaaatg ctaatgtcaa ctacaaatca aaagtgctga
1741 gttaatgctt tgtgcctggt gctctgtaat gaaccaggca atgagatagt tttctcagtt
1801 tggtttcagc agttaatgtg ctttcttgga tccaaattta aatatcttcc taaaccaaaa
1861 ctgtaaatat ggttgttgca tgagcaacag aaaaaattgt ttaaatgctt gaagcaaagt
1921 atggatgtct tctctaaatc tttctttctt tttttttttt tttttttttt t
//