LOCUS AY158070 1326 bp mRNA linear HUM 24-JUL-2016
DEFINITION Homo sapiens N-acetylglutamate synthase (NAGS) mRNA, partial cds;
nuclear gene for mitochondrial product.
ACCESSION AY158070
VERSION AY158070.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1326)
AUTHORS Caldovic,L., Morizono,H., Yu,X., Thompson,M., Shi,D., Gallegos,R.,
Allewell,N.M., Malamy,M.H. and Tuchman,M.
TITLE Identification, cloning and expression of the mouse
N-acetylglutamate synthase gene
JOURNAL Biochem. J. 364 (PT 3), 825-831 (2002)
PUBMED 12049647
REFERENCE 2 (bases 1 to 1326)
AUTHORS Caldovic,L., Morizono,H., Gracia Panglao,M., Gallegos,R., Yu,X.,
Shi,D., Malamy,M.H., Allewell,N.M. and Tuchman,M.
TITLE Cloning and expression of the human N-acetylglutamate synthase gene
JOURNAL Biochem. Biophys. Res. Commun. 299 (4), 581-586 (2002)
PUBMED 12459178
REFERENCE 3 (bases 1 to 1326)
AUTHORS Caldovic,L., Morizono,H. and Tuchman,M.
TITLE Direct Submission
JOURNAL Submitted (03-OCT-2002) Research Center for Genetic Medicine,
Children's National Medical Center, 111 Michigan Ave NW,
Washington, DC 20010, USA
FEATURES Location/Qualifiers
source 1..1326
/db_xref="H-InvDB:HIT000084845"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="17"
/map="17q21.31"
gene <1..1326
/gene="NAGS"
CDS <1..1326
/gene="NAGS"
/EC_number="2.3.1.1"
/note="amino acid acetyltransferase; conserved domain"
/codon_start=1
/product="N-acetylglutamate synthase"
/protein_id="AAN76451.1"
/translation="MPPSGRSLVQRDIQAFLNQCGASPGEARHWLTQFQTCHHSADKP
FAVIEVDEEVLKCQQGVSSLAFALAFLQRMDMKPLVVLGLPAPTAPSGCLSFWEAKAQ
LAKSCKVLVDALRHNAAAAVPFFGGGSVLRAAEPAPHASYGGIVSVETDLLQWCLESG
SIPILCPIGETAARRSVLLDSLEVTASLAKALRPTKIIFLNNTGGLRDSSHKVLSNVN
LPADLDLVCNAEWVSTKERQQMRLIVDVLSRLPHHSSAVITAASTLLTELFSNKGSGT
LFKNAERMLRVRSLDKLDQGRLVDLVNASFGKKLRDDYLASLRPRLHSIYVSEGYNAA
AILTMEPVLGGTPYLDKFVVSSSRQGQGSGQMLWECLRRDLQTLFWRSRVTNPINPWY
FKHSDGSFSNKQWIFFWFGLADIRDSYELVNHAKGLPDSFHKPASDPGS"
BASE COUNT 230 a 449 c 403 g 244 t
ORIGIN
1 atgcctcctt cgggccgctc gctggtgcag cgggacatcc aggccttcct gaaccagtgc
61 ggggccagcc ctggggaggc gcgccactgg ctcacgcagt tccagacctg ccatcactcc
121 gcggacaagc ccttcgccgt catcgaggtg gacgaggagg tgctcaagtg ccagcagggc
181 gtatccagtc tggcctttgc cctggccttc ttgcagcgca tggacatgaa gccgctggtg
241 gtcctggggc tgccggcccc tacggctccc tcgggctgtc tttccttctg ggaggccaag
301 gcgcagctgg ccaagagctg caaggtgctg gtagacgcgc ttcgacacaa cgccgccgct
361 gctgtgccat tttttggcgg cgggtctgtg ctacgcgctg ccgagccggc tccccatgcc
421 agctacggcg gcatcgtctc ggtggagaca gacctgctgc agtggtgcct ggagtcgggc
481 agcatcccca tcctgtgccc catcggggag acggccgcgc gccgctccgt gcttctcgac
541 tccctggagg tgaccgcgtc gctggccaag gcgctgcggc ccaccaaaat catcttcctc
601 aataacacag gcggcctgcg cgacagcagt cataaggtcc tgagtaacgt gaacctgccc
661 gccgacctgg acctggtgtg caacgccgag tgggtgagca caaaagaacg gcagcagatg
721 cggctcatcg tggacgtgct cagccgcctg ccccaccact cctcggccgt catcaccgcc
781 gctagcacgc tgctcactga gctctttagc aacaaggggt ccgggaccct gttcaagaac
841 gccgagcgaa tgctacgggt gcgcagcctg gacaagctgg accagggccg tctagtggac
901 ctggtcaacg ccagcttcgg caagaagctc agggacgact acctggcctc gctgcgcccg
961 cggctgcact ccatctacgt ctccgagggg tacaacgccg ccgccattct gaccatggag
1021 cccgtcctgg ggggcacccc gtacctggac aaatttgtgg tgagctccag ccgccagggc
1081 caaggctccg gccagatgct gtgggagtgc ctgcggcggg accttcagac acttttctgg
1141 cgctcccggg tcaccaaccc catcaatccc tggtacttca aacacagtga tggcagcttc
1201 tccaacaagc agtggatctt cttctggttt ggcctggctg atatccggga ctcctatgag
1261 ttggtcaacc acgccaaggg actgccagac tcctttcaca agccagcttc tgacccaggc
1321 agctga
//