LOCUS AY157302 3404 bp mRNA linear HUM 14-APR-2005
DEFINITION Homo sapiens neuronal PAS3 transcript variant 1 (NPAS3) mRNA,
complete cds.
ACCESSION AY157302
VERSION AY157302.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3404)
AUTHORS Kamnasaran,D., Muir,W.J., Ferguson-Smith,M.A. and Cox,D.W.
TITLE Disruption of the neuronal PAS3 gene in a family affected with
schizophrenia
JOURNAL J. Med. Genet. 40 (5), 325-332 (2003)
PUBMED 12746393
REFERENCE 2 (bases 1 to 3404)
AUTHORS Kamnasaran,D., Chen,C.P., Devriendt,K., Mehta,L. and Cox,D.W.
TITLE Defining a holoprosencephaly locus on human chromosome 14q13 and
characterization of potential candidate genes
JOURNAL Genomics 85 (5), 608-621 (2005)
PUBMED 15820313
REFERENCE 3 (bases 1 to 3404)
AUTHORS Kamnasaran,D. and Cox,D.W.
TITLE Cloning and characterization of a novel gene expressed in human
fetal brain
JOURNAL Unpublished
REFERENCE 4 (bases 1 to 3404)
AUTHORS Kamnasaran,D. and Cox,D.W.
TITLE Direct Submission
JOURNAL Submitted (30-SEP-2002) Medical Genetics, University of Alberta,
843 Medical Sciences Building, Edmonton, AB T6G 2H7, Canada
FEATURES Location/Qualifiers
source 1..3404
/db_xref="H-InvDB:HIT000250846"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="14"
/map="14q13"
/tissue_type="brain"
/dev_stage="fetus"
gene 1..3404
/gene="NPAS3"
CDS 65..2770
/gene="NPAS3"
/note="transcription factor"
/codon_start=1
/product="neuronal PAS3 transcript variant 1"
/protein_id="AAO17043.1"
/translation="MAPTKPSFQQDPSRRERLQALRKEKSRDAARSRRGKENFEFYEL
AKLLPLPAAITSQLDKASIIRLTISYLKMRDFANQGDPPWNLRMEGPPPNTSVKGAQR
RRSPSALAIEVFEAHLGSHILQSLDGFVFALNQEGKFLYISETVSIYLGLSQVELTGS
SVFDYVHPGDHVEMAEQLGMKLPPGRGLLSQGTAEDGASSASSSSQSETPEPVESTSP
SLLTTDNTLERSFFIRMKSTLTKRGVHIKSSGYKVIHITGRLRLRVSLSHGRTVPSQI
MGLVVVAHALPPPTINEVRIDCHMFVTRVNMDLNIIYCENRISDYMDLTPVDIVGKRC
YHFIHAEDVEGIRHSHLDLLNKGQCVTKYYRWMQKNGGYIWIQSSATIAINAKNANEK
NIIWVNYLLSNPEYKDTPMDIAQLPHLPEKTSESSETSDSESDSKDTSGITEDNENSK
SDEKGNQSENSEDPEPDRKKSGNACDNDMNCNDDGHSSSNPDSRDSDDSFEHSDFENP
KAGEDGFGALGPMQIKVERYVESESDLRLQNCESLTSDSAKDSDSAGEAGAQASSKHQ
KRKKRRKRQKGGSASRRRLSSASSPGGLDAGLVEPPRLLSSPNSASVLKIKTEISEPI
NFDNDSSIWNYPPNREISRNESPYSMTKPPSSEHFPSPQGGGGGGGGGGGLHVAIPDS
VLTPPGADGAAARKTQFGASATAALAPVASDPLSPPLSASPRDKHPGNGGGGGGGGGG
AGGGGPSASNSLLYTGDLEALQRLQAGNVVLPLVHRVTGTLAATSTAAQRVYTTGTIR
YAPAEVTLAMQSNLLPNAHAVNFVDVNSPGFGLDPKTPMEMLYHHVHRLNMSGPFGGA
VSAASLTQMPAGNVFTTAEGLFSTLPFPVYSNGIHAAQTLERKED"
BASE COUNT 812 a 979 c 922 g 691 t
ORIGIN
1 acgcccccca cccgggaggg gggagagagg caaaaagtaa gagaggaaaa aaaatagcag
61 gaagatggcg cccaccaagc ccagctttca gcaggatcct tccaggcgag aacgtttaca
121 agcattgaga aaggagaaat cccgagatgc tgctcgctcc cgccggggaa aagaaaactt
181 tgagttctat gaattggcca agttgttgcc tcttcctgca gccattacca gccagctcga
241 caaggcatcc atcattcgac ttacaattag ctatctgaaa atgagggact ttgctaacca
301 gggggaccct ccgtggaact tgcgaatgga aggccctcca cctaacacat cagtaaaagg
361 tgcacagcga aggagaagcc ccagtgcact agccattgaa gtatttgaag cacatttggg
421 aagccacatt ttgcagtccc tggatggctt tgtatttgca ctaaatcagg aaggaaaatt
481 tttgtacatt tccgaaacag tctccatcta cctaggcctc tcacaagtgg agctgacagg
541 cagcagtgtc tttgactatg tccaccccgg agatcacgtg gagatggctg agcagctggg
601 catgaagctc ccccctgggc ggggtctcct gtcacagggc actgctgagg acggagccag
661 ctcagcatct tcctcctctc agtcggagac ccccgagcca gtggagtcaa ccagccccag
721 tctgctaacc actgacaaca ctcttgagcg ttcctttttc atccgaatga aatctactct
781 gaccaaacgc ggtgtgcaca tcaaatcatc aggatataag gtgattcaca taacaggccg
841 gctacgcctg agagtgtcgc tgtcccacgg gaggaccgtc cccagccaaa tcatgggtct
901 cgtggttgtt gcgcatgcct tgcctccccc tacgatcaat gaagtcagaa ttgactgcca
961 tatgttcgtc actcgagtaa atatggacct caatatcatt tactgtgaaa ataggattag
1021 tgattatatg gatctgaccc ctgtagatat cgtagggaag agatgctacc acttcatcca
1081 tgctgaagac gtggagggca tcaggcacag tcacttggac ttgctgaata agggtcagtg
1141 tgtgacaaag tactatcgct ggatgcagaa gaacggagga tatatttgga tacagtccag
1201 tgccaccata gctattaatg ccaagaatgc aaatgaaaag aatatcatct gggtgaatta
1261 ccttcttagc aatcctgagt acaaggacac acccatggac atcgcacagc tcccccatct
1321 gccggagaaa acttccgaat cctcggagac atccgactct gagtcagact ctaaagacac
1381 ctcaggtatt acagaggaca acgagaactc caagtccgac gagaagggga accagtccga
1441 gaacagcgaa gacccggagc ccgaccggaa gaagtcgggc aacgcgtgtg acaacgacat
1501 gaactgcaac gacgacggcc acagctccag taacccggac agccgcgaca gcgacgacag
1561 cttcgagcac tcggactttg agaaccccaa ggcgggcgag gacggcttcg gtgctctggg
1621 cccgatgcag atcaaggtgg agcgctacgt ggagagcgag tcggacctgc ggctgcagaa
1681 ctgcgagtca ctcacgtccg acagcgccaa ggactcggac agcgcaggcg aggcgggcgc
1741 gcaggcctcc agcaagcacc agaagcgcaa gaaaaggcgg aaacggcaaa agggcggcag
1801 cgccagccgc cggcgccttt ccagcgcgtc gagcccaggc ggcctggacg cgggcctggt
1861 ggagcccccg cggctgctgt cctcccccaa cagtgcctcg gtgctcaaga tcaagacgga
1921 gatctcagaa cccatcaatt tcgacaatga cagcagcatc tggaactacc cgcccaaccg
1981 ggagatctcc aggaacgagt ccccctacag catgaccaag ccccccagct ctgagcactt
2041 cccgtccccg cagggcggcg gcggtggggg tggcggtggc ggggggctgc acgtggccat
2101 tcccgactcg gtcctcaccc cgcccggcgc cgacggcgcg gccgcccgca agactcagtt
2161 cggcgcctcg gccaccgcgg ccctggcccc cgtcgcctcc gacccgctgt cacccccgct
2221 ctcggcgtcc ccgcgggaca agcaccccgg gaacggcggc gggggcgggg gcgggggcgg
2281 cggcgcgggg ggcggcggcc ccagcgcgtc caactccttg ctgtacactg gggacctgga
2341 ggcgctgcag aggttgcagg cgggcaacgt cgtgctcccg ctggtgcaca gggtgaccgg
2401 gaccctggcc gccaccagca cggccgcgca gagggtctac accacgggca ccatccgcta
2461 cgcgcccgcc gaggtgaccc tggccatgca gagcaacctg ctgcccaacg cgcacgctgt
2521 taacttcgtg gacgttaaca gccccggctt tggcctcgac cccaagacgc ccatggagat
2581 gctctaccac cacgtgcacc ggctcaacat gtcaggaccg ttcggcggcg cagtgagcgc
2641 agctagcctg acgcagatgc ccgccggcaa cgtgttcacc acggccgagg gactcttctc
2701 cacgctgccc ttccccgtct acagcaacgg catccacgcg gcacagactc tggagcgcaa
2761 ggaggactga ggcgccgccc gtcctgggcc cggccaggcc ccgcttggag gaggcatcgt
2821 cggcattttc gtttagacct ttaattctag cactttgaat tcgagcaggt cagcgtcttc
2881 tctcgccacg acggtcccca ttccaccccc tctttctttc acctgactta ttctttcgtg
2941 taaagatatg tttatttttt gccttcagag ggtcagacga ccagttgcct gccgttttgt
3001 cttcttctaa ggtgtgtgtt gggttgtttt gctttccttt gcatctttat taagatgtct
3061 ttcatgtgta tatgcctctg ccatagaata ctcagtcttg tggtcaagag agttctcaag
3121 tgacaaccat tggggtttct tcataaagat cttgatatga tcaagatgga aagagacaag
3181 cataaacaat gtgccctgtt tgactaagtc aaatgaaata gggtggtttt tgtttctgtt
3241 cctaattcct ttaaaaaata gggggaatag tattttagaa ttttatgcag aatctaattc
3301 tctttttacg gttaagattc taagattatc ttacttgcac ataaaaataa tttgggttct
3361 taaacttaat ttctggcctg tgactagaat gtttaaaaaa aaaa
//