LOCUS AY154467 3827 bp mRNA linear HUM 20-FEB-2003
DEFINITION Homo sapiens NALP12 (NALP12) mRNA, complete cds.
ACCESSION AY154467
VERSION AY154467.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3827)
AUTHORS Tschopp,J., Martinon,F. and Burns,K.
TITLE NALPs: a novel protein family involved in inflammation
JOURNAL Nat. Rev. Mol. Cell Biol. 4 (2), 95-104 (2003)
PUBMED 12563287
REFERENCE 2 (bases 1 to 3827)
AUTHORS Martinon,F., Hofmann,K. and Tschopp,J.
TITLE Direct Submission
JOURNAL Submitted (25-SEP-2002) Institute of Biochemistry, University of
Lausanne, ch. des Boveresses 155, Epalinges, VD 1066, Switzerland
FEATURES Location/Qualifiers
source 1..3827
/db_xref="H-InvDB:HIT000084799"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..3827
/gene="NALP12"
CDS 177..3362
/gene="NALP12"
/note="member of the NALP protein family involved in
inflammation; contains NACHT, LRR and PYD domains"
/codon_start=1
/product="NALP12"
/protein_id="AAO18163.1"
/translation="MLRTAGRDGLCRLSTYLEELEAVELKKFKLYLGTATELGEGKIP
WGSMEKAGPLEMAQLLITHFGPEEAWRLALSTFERINRKDLWERGQREDLVRDTPPGG
PSSLGNQSTCLLEVSLVTPRKDPQETYRDYVRRKFRLMEDRNARLGECVNLSHRYTRL
LLVKEHSNPMQVQQQLLDTGRGHARTVGHQASPIKIETLFEPDEERPEPPRTVVMQGA
AGIGKSMLAHKVMLDWADGKLFQGRFDYLFYINCREMNQSATECSMQDLIFSCWPEPS
APLQELIRVPERLLFIIDGFDELKPSFHDPQGPWCLCWEEKRPTELLLNSLIRKKLLP
ELSLLITTRPTALEKLHRLLEHPRHVEILGFSEAERKEYFYKYFHNAEQAGQVFNYVR
DNEPLFTMCFVPLVCWVVCTCLQQQLEGGGLLRQTSRTTTAVYMLYLLSLMQPKPGAP
RLQPPPNQRGLCSLAADGLWNQKILFEEQDLRKHGLDGEDVSAFLNMNIFQKDINCER
YYSFIHLSFQEFFAAMYYILDEGEGGAGPDQDVTRLLTEYAFSERSFLALTSRFLFGL
LNEETRSHLEKSLCWKVSPHIKMDLLQWIQSKAQSDGSTLQQGSLEFFSCLYEIQEEE
FIQQALSHFQVIVVSNIASKMEHMVSSFCLKRCRSAQVLHLYGATYSADGEDRARCSA
GAHTLLVQLPERTVLLDAYSEHLAAALCTNPNLIELSLYRNALGSRGVKLLCQGLRHP
NCKLQNLRLKRCRISSSACEDLSAALIANKNLTRMDLSGNGVGFPGMMLLCEGLRHPQ
CRLQMIQLRKCQLESGACQEMASVLGTNPHLVELDLTGNALEDLGLRLLCQGLRHPVC
RLRTLWLKICRLTAAACDELASTLSVNQSLRELDLSLNELGDLGVLLLCEGLRHPTCK
LQTLRLGICRLGSAACEGLSVVLQANHNLRELDLSFNDLGDWGLWLLAEGLQHPACRL
QKLWLDSCGLTAKACENLYFTLGINQTLTDLYLTNNALGDTGVRLLCKRLSHPGCKLR
VLWLFGMDLNKMTHSRLAALRVTKPYLDIGC"
BASE COUNT 856 a 1085 c 1120 g 766 t
ORIGIN
1 ccacgcgtcc ggcaaaaggt ctttcctccc ttgctctctc ctccaaccac tggctcagcc
61 tctccgcccg ctgcctgtga atgatgcaat ggaaggtgtg ctggggtcgc cctgtgtccc
121 gtgcatagga gcatctcagc ctccaggtcc tctcctttgg ggctcacggc acccccatgc
181 tacgaaccgc aggcagggac ggcctctgtc gcctgtccac ctacttggaa gaactcgagg
241 ctgtggaact gaagaagttc aagttatacc tggggaccgc gacagagctg ggagaaggca
301 agatcccctg gggaagcatg gagaaggccg gtcccctgga aatggcccag ctgctcatca
361 cccacttcgg gccagaggag gcctggaggt tggctctcag cacctttgag cggataaaca
421 ggaaggacct gtgggagaga ggacagagag aggacctggt gagggatacc ccacctggtg
481 gcccgtcctc acttgggaac cagtcaacat gccttctgga agtctctctt gtcactccaa
541 gaaaagatcc ccaggaaacc tacagggact atgtccgcag gaaattccgg ctcatggaag
601 accgcaatgc gcgcctaggg gaatgtgtca acctcagcca ccggtacacc cggctcctgc
661 tggtgaagga gcactcaaac cccatgcagg tccagcagca gcttctggac acaggccggg
721 gacacgcgag gaccgtggga caccaggcta gccccatcaa gatagagacc ctctttgagc
781 cagacgagga gcgccccgag ccaccgcgca ccgtggtcat gcaaggcgcg gcagggatag
841 gcaagtccat gctggcacac aaggtgatgc tggactgggc ggacgggaag ctcttccaag
901 gcagatttga ttatctcttc tacatcaact gcagggagat gaaccagagt gccacggaat
961 gcagcatgca agacctcatc ttcagctgct ggcctgagcc cagcgcgcct ctccaggagc
1021 tcatccgagt tcccgagcgc ctccttttca tcatcgacgg cttcgatgag ctcaagcctt
1081 ctttccacga tcctcaggga ccctggtgcc tctgctggga ggagaaacgg cccacggagc
1141 tgcttcttaa cagcttaatt cggaagaagc tgctccctga gctatctttg ctcatcacca
1201 cacggcccac ggctttggag aagctccacc gtctgctgga gcaccccagg catgtggaga
1261 tcctgggctt ctctgaggca gaaaggaagg aatacttcta caagtatttc cacaatgcag
1321 agcaggcggg ccaagtcttc aattacgtga gggacaacga gcctctcttc accatgtgct
1381 tcgtccccct ggtgtgctgg gtggtgtgta cctgcctcca gcagcagctg gagggtgggg
1441 ggctgttgag acagacgtcc aggaccacca ctgcagtgta catgctctac ctgctgagtc
1501 tgatgcaacc caagccgggg gccccgcgcc tccagccccc acccaaccag agagggttgt
1561 gctccttggc ggcagatggg ctctggaatc agaaaatcct atttgaggag caggacctcc
1621 ggaagcacgg cctagacggg gaagacgtct ctgccttcct caacatgaac atcttccaga
1681 aggacatcaa ctgtgagagg tactacagct tcatccactt gagtttccag gaattctttg
1741 cagctatgta ctatatcctg gacgaggggg agggcggggc aggcccagac caggacgtga
1801 ccaggctgtt gaccgagtac gcgttttctg aaaggagctt cctggcactc accagccgct
1861 tcctgtttgg actcctgaac gaggagacca ggagccacct ggagaagagt ctctgctgga
1921 aggtctcgcc gcacatcaag atggacctgt tgcagtggat ccaaagcaaa gctcagagcg
1981 acggctccac cctgcagcag ggctccttgg agttcttcag ctgcttgtac gagatccagg
2041 aggaggagtt tatccagcag gccctgagcc acttccaggt gatcgtggtc agcaacattg
2101 cctccaagat ggagcacatg gtctcctcgt tctgtctgaa gcgctgcagg agcgcccagg
2161 tgctgcactt gtatggcgcc acctacagcg cggacgggga agaccgcgcg aggtgctccg
2221 caggagcgca cacgctgttg gtgcagctac cagagaggac cgttctgctg gacgcctaca
2281 gtgaacatct ggcagcggcc ctgtgcacca atccaaacct gatagagctg tctctgtacc
2341 gaaatgccct gggcagccgg ggggtgaagc tgctctgtca aggactcaga caccccaact
2401 gcaaacttca gaacctgagg ctgaagaggt gccgcatctc cagctcagcc tgcgaggacc
2461 tctctgcagc tctcatagcc aataagaatt tgacaaggat ggatctcagt ggcaacggcg
2521 ttggattccc aggcatgatg ctgctttgcg agggcctgcg gcatccccaa tgcaggctgc
2581 agatgattca gttgaggaag tgtcagctgg agtccggggc ttgtcaggag atggcttctg
2641 tgcttggcac caacccacat ctggttgagt tggacctgac aggaaatgca ctggaggatt
2701 tgggcctgag gttactatgc cagggactga ggcacccagt ctgcagacta cggactttgt
2761 ggctgaagat ctgccgcctc actgctgctg cctgtgacga gctggcctca actctcagtg
2821 tgaaccagag cctgagagag ctggacctga gcctgaatga gctgggggac ctcggggtgc
2881 tgctgctgtg tgagggcctc aggcatccca cgtgcaagct ccagaccctg cggttgggca
2941 tctgccggct gggctctgcc gcctgtgagg gtctttctgt ggtgctccag gccaaccaca
3001 acctccggga gctggacttg agtttcaacg acctgggaga ctggggcctg tggttgctgg
3061 ctgaggggct gcaacatccc gcctgcagac tccagaaact gtggctggat agctgtggcc
3121 tcacagccaa ggcttgtgag aatctttact tcaccctggg gatcaaccag accttgaccg
3181 acctttacct gaccaacaac gccctagggg acacaggtgt ccgactgctt tgcaagcggc
3241 tgagccatcc tggctgcaaa ctccgagtcc tctggttatt tgggatggac ctgaataaaa
3301 tgacccacag taggttggca gcgcttcgag taacaaaacc ttatttggac attggctgct
3361 gaatggtcct atctgctggc tctcccctga gatctggaca gaggaagatg ggagggtgct
3421 catcaccccc ccagcataat gatcagcctc cttcctagag acagactcat gcagattgag
3481 atcaaaagtc cctctgcttg ggatcaaatt aatgtttgac agagctggcc aggcgtggtg
3541 gctcatgtat gtaatcctag cacttcgaga ggccgaggca ggtggatcac gaggtcagga
3601 gtttgagatt agcctggcca agatggtgaa accctgtctc tactaaaaat aaaaaaaaat
3661 tagccaggca tggtggcggg cacctgtagt cccagctact caggaggctg aggcaggaga
3721 atcgcttgaa cccgggaggt ggaggttgca gtgagccgag atcgcgccac tgcactccag
3781 cctgggcgac agagtgggac tccatctcaa aaaaaaaaaa aaaaaaa
//