LOCUS AY154461 2679 bp mRNA linear HUM 20-FEB-2003
DEFINITION Homo sapiens NALP6 (NALP6) mRNA, complete cds.
ACCESSION AY154461
VERSION AY154461.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2679)
AUTHORS Tschopp,J., Martinon,F. and Burns,K.
TITLE NALPs: a novel protein family involved in inflammation
JOURNAL Nat. Rev. Mol. Cell Biol. 4 (2), 95-104 (2003)
PUBMED 12563287
REFERENCE 2 (bases 1 to 2679)
AUTHORS Martinon,F., Hofmann,K. and Tschopp,J.
TITLE Direct Submission
JOURNAL Submitted (25-SEP-2002) Institute of Biochemistry, University of
Lausanne, ch. des Boveresses 155, Epalinges, VD 1066, Switzerland
FEATURES Location/Qualifiers
source 1..2679
/db_xref="H-InvDB:HIT000084793"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2679
/gene="NALP6"
CDS 1..2679
/gene="NALP6"
/note="member of the NALP protein family involved in
inflammation; contains NACHT, LRR and PYD domains"
/codon_start=1
/product="NALP6"
/protein_id="AAO18157.1"
/translation="MDQPEAPCSSTGPRLAVARELLLAALEELSQEQLKRFRHKLRDV
GPDGRSIPWGRLERADAVDLAEQLAQFYGPEPALEVARKTLKRADARDVAAQLQERRL
QRLGLGSGTLLSVSEYKKKYREHVLQLHARVKERNARSVKITKRFTKLLIAPESAAPE
EALGPAEEPEPGRARRSDTHTFNRLFRRDEEGRRPLTVVLQGPAGIGKTMAAKKILYD
WAAGKLYQGQVDFAFFMPCGELLERPGTRSLADLILDQCPDRGAPVPQMLAQPQRLLF
ILDGADELPALGGPEAAPCTDPFEAASGARVLGGLLSKALLPTALLLVTTRAAAPGRL
QGRLCSPQCAEVRGFSDKDKKKYFYKFFRDERRAERAYRFVKENETLFALCFVPFVCW
IVCTVLRQQLELGRDLSRTSKTTTSVYLLFITSVLSSAPVADGPRLQGDLRNLCRLAR
EGVLGRRAQFAEKELEQLELRGSKVQTLFLSKKELPGVLETEVTYQFIDQSFQEFLAA
LSYLLEDGGVPRTAAGGVGTLLRGDAQPHSHLVLTTRFLFGLLSAERMRDIERHFGCM
VSERVKQEALRWVQGQGQGCPGVAPEVTEGAKGLEDTEEPEEEEEGEEPNYPLELLYC
LYETQEDAFVRQALCRFPELALQRVRFCRMDVAVLSYCVRCCPAGQALRLISCRLVAA
QEKKKKSLGKRLQASLGGGSSSQGTTKQLPASLLHPLFQAMTDPLCHLSSLTLSHCKL
PDAVCRDLSEALRAAPALTELGLLHNRLSEAGLRMLSEGLAWPQCRVQTVRVQLPDPQ
RGLQYLVGMLRQSPALTTLDLSGCQLPAPMVTYLCAVLQHQGCGLQTLSLASVELSEQ
SLQELQAVKRAKPDLVITHPALDGHPQPPKELISTF"
BASE COUNT 458 a 878 c 934 g 409 t
ORIGIN
1 atggaccagc cagaggcccc ctgctccagc acggggccgc gcctcgcggt ggcccgcgag
61 ctgctcctgg ctgcgctgga ggaactgagc caagagcagc tgaagcgctt ccgccacaag
121 ctgcgcgacg tgggcccgga cggacgcagc atcccgtggg ggcggctgga gcgcgcggac
181 gccgtggacc tcgcggagca gctggcccag ttctacggcc cggagcctgc cctggaggtg
241 gcccgcaaga ccctcaagag ggcggacgcg cgcgacgtgg cggcgcagct ccaggagcgg
301 cggctgcagc ggctcgggct cggctccggg acgctgctct ccgtgtccga gtacaagaag
361 aagtaccggg agcacgtgct gcagctgcac gctcgggtga aggagaggaa cgcccgctcc
421 gtgaagatca ccaagcgctt caccaagctg ctcatcgcgc ccgagagcgc cgccccggag
481 gaggcgctgg ggcccgcgga agagcctgag ccggggcgcg cgcggcgctc ggacacgcac
541 actttcaacc gcctcttccg ccgcgacgag gagggccggc ggccgctgac cgtggtgctg
601 cagggcccgg cgggcatcgg caagaccatg gcggccaaaa agatcctgta cgactgggcg
661 gcgggcaagc tgtaccaggg ccaggtggac ttcgccttct tcatgccctg cggcgagctg
721 ctggagaggc cgggcacgcg cagcctggct gacctgatcc tggaccagtg ccccgaccgc
781 ggcgcgccgg tgccgcagat gctggcccag ccgcagcggc tgctcttcat cctggacggc
841 gcggacgagc tgccggcgct ggggggcccc gaggccgcgc cctgcacaga ccccttcgag
901 gcggcgagcg gcgcgcgggt gctaggcggg ctgctgagca aggcgctgct gcccacggcc
961 ctcctgctgg tgaccacgcg cgccgccgcc cccgggaggc tgcagggccg cctgtgttcc
1021 ccgcagtgcg ccgaggtgcg cggcttctcc gacaaggaca agaagaagta tttctacaag
1081 ttcttccggg atgagaggag ggccgagcgc gcctaccgct tcgtgaagga gaacgagacg
1141 ctgttcgcgc tgtgcttcgt gcccttcgtg tgctggatcg tgtgcaccgt gctgcgccag
1201 cagctggagc tcggtcggga cctgtcgcgc acgtccaaga ccaccacgtc agtgtacctg
1261 cttttcatca ccagcgttct gagctcggct ccggtagccg acgggccccg gttgcagggc
1321 gacctgcgca atctgtgccg cctggcccgc gagggcgtcc tcggacgcag ggcgcagttt
1381 gccgagaagg aactggagca actggagctt cgtggctcca aagtgcagac gctgtttctc
1441 agcaaaaagg agctgccggg cgtgctggag acagaggtca cctaccagtt catcgaccag
1501 agcttccagg agttcctcgc ggcactgtcc tacctgctgg aggacggcgg ggtgcccagg
1561 accgcggctg gcggcgttgg gacactcctg cgtggggacg cccagccgca cagccacttg
1621 gtgctcacca cgcgcttcct cttcggactg ctgagcgcgg agcggatgcg cgacatcgag
1681 cgccacttcg gctgcatggt ttcagagcgt gtgaagcagg aggccctgcg gtgggtgcag
1741 ggacagggac agggctgccc cggagtggca ccagaggtga ccgagggggc caaagggctc
1801 gaggacaccg aagagccaga ggaggaggag gagggagagg agcccaacta cccactggag
1861 ttgctgtact gcctgtacga gacgcaggag gacgcgtttg tgcgccaagc cctgtgccgg
1921 ttcccggagc tggcgctgca gcgagtgcgc ttctgccgca tggacgtggc tgttctgagc
1981 tactgcgtga ggtgctgccc tgctggacag gcactgcggc tgatcagctg cagattggtt
2041 gctgcgcagg agaagaagaa gaagagcctg gggaagcggc tccaggccag cctgggtggc
2101 ggcagcagtt ctcaaggcac cacaaaacaa ctgccagcct cccttcttca tccactcttt
2161 caggcaatga ctgacccact gtgccatctg agcagcctca cgctgtccca ctgcaaactc
2221 cctgacgcgg tctgccgaga cctttctgag gccctgaggg cagcccccgc actgacggag
2281 ctgggcctcc tccacaacag gctcagtgag gcgggactgc gtatgctgag tgagggccta
2341 gcctggccgc agtgcagggt gcagacggtc agggtacagc tgcctgaccc ccagcgaggg
2401 ctccagtacc tggtgggtat gcttcggcag agccctgccc tgaccaccct ggatctcagc
2461 ggctgccaac tgcccgcccc catggtgacc tacctgtgtg cagtcctgca gcaccaggga
2521 tgcggcctgc agaccctcag tctggcctct gtggagctga gcgagcagtc actacaggag
2581 cttcaggctg tgaagagagc aaagccggat ctggtcatca cacacccagc gctggacggc
2641 cacccacaac ctcccaagga actcatctcg accttctga
//