LOCUS AY154460 3885 bp mRNA linear HUM 20-FEB-2003
DEFINITION Homo sapiens NALP5 (NALP5) mRNA, complete cds.
ACCESSION AY154460
VERSION AY154460.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3885)
AUTHORS Tschopp,J., Martinon,F. and Burns,K.
TITLE NALPs: a novel protein family involved in inflammation
JOURNAL Nat. Rev. Mol. Cell Biol. 4 (2), 95-104 (2003)
PUBMED 12563287
REFERENCE 2 (bases 1 to 3885)
AUTHORS Martinon,F., Hofmann,K. and Tschopp,J.
TITLE Direct Submission
JOURNAL Submitted (25-SEP-2002) Institute of Biochemistry, University of
Lausanne, ch. des Boveresses 155, Epalinges, VD 1066, Switzerland
FEATURES Location/Qualifiers
source 1..3885
/db_xref="H-InvDB:HIT000084792"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..3885
/gene="NALP5"
CDS 1..3603
/gene="NALP5"
/note="member of the NALP protein family involved in
inflammation; contains NACHT, LRR and PYD domains; similar
to mouse MATER protein"
/codon_start=1
/product="NALP5"
/protein_id="AAO18156.1"
/translation="MKVAGGLELGAAALLSASPRALVTLSTGPTCSILPKNPLFPQNL
SSQPCIKMEGDKSLTFSSYGLQWCLYELDKEEFQTFKELLKKKSSESTTCSIPQFEIE
NANVECLALLLHEYYGASLAWATSISIFENMNLRTLSEKARDDMKRHSPEDPEATMTD
QGPSKEKVPGISQAVQQDSATAAETKEQEISQAMEQEGATAAETEEQEISQAMEQEGA
TAAETEEQGHGGDTWDYKSHVMTKFAEEEDVRRSFENTAADWPEMQTLAGAFDSDRWG
FRPRTVVLHGKSGIGKSALARRIVLCWAQGGLYQGMFSYVFFLPVREMQRKKESSVTE
FISREWPDSQAPVTEIMSRPERLLFIIDGFDDLGSVLNNDTKLCKDWAEKQPPFTLIR
SLLRKVLLPESFLIVTVRDVGTEKLKSEVVSPRYLLVRGISGEQRIHLLLERGIGEHQ
KTQGLRAIMNNRELLDQCQVPAVGSLICVALQLQDVVGESVAPFNQTLTGLHAAFVFH
QLTPRGVVRRCLNLEERVVLKRFCRMAVEGVWNRKSVFDGDDLMVQGLGESELRALFH
MNILLPDSHCEEYYTFFHLSLQDFCAALYYVLEGLEIEPALCPLYVEKTKRSMELKQA
GFHIHSLWMKRFLFGLVSEDVRRPLEVLLGCPVPLGVKQKLLHWVSLLGQQPNATTPG
DTLDAFHCLFETQDKEFVRLALNSFQEVWLPINQNLDLIASSFCLQHCPYLRKIRVDV
KGIFPRDESAEACPVVPLWMRDKTLIEEQWEDFCSMLGTHPHLRQLDLGSSILTERAM
KTLCAKLRHPTCKIQTLMFRNAQITPGVQHLWRIVMANRNLRSLNLGGTHLKEEDVRM
ACEALKHPKCLLESLRLDCCGLTHACYLKISQILTTSPSLKSLSLAGNKVTDQGVMPL
SDALRVSQCALQKLILEDCGITATGCQSLASALVSNRSLTHLCLSNNSLGNEGVNLLC
RSMRLPHCSLQRLMLNQCHLDTAGCGFLALALMGNSWLTHLSLSMNPVEDNGVKLLCE
VMREPSCHLQDLELVKCHLTAACCESLSCVISRSRHLKSLDLTDNALGDGGVAALCEG
LKQKNSVLTRLGLKACGLTSDCCEALSLALSCNRHLTSLNLVQNNFSPKGMMKLCSAF
ACPTSNLQIIGLWKWQYPVQIRKLLEEVQLLKPRVVIDGSWHSFDEDDRYWWKN"
BASE COUNT 968 a 984 c 1043 g 890 t
ORIGIN
1 atgaaggttg caggaggact tgaacttgga gctgctgctc tgctctcagc atcaccacgt
61 gctcttgtca ctctttccac aggtcctact tgctctatat taccaaagaa tccacttttc
121 ccccaaaacc tgagctctca gccttgtatc aagatggaag gagacaaatc gctcaccttt
181 tccagctacg ggctgcaatg gtgtctctat gagctagaca aggaagaatt tcagacattc
241 aaggaattac taaagaagaa atcttcagaa tcgaccacat gctctattcc acagtttgaa
301 atcgagaatg ccaacgtgga atgtctggca ctcctcttgc atgagtatta tggagcatcg
361 ctggcctggg ctacgtccat tagcatcttt gaaaacatga acctgcgaac cctctcggag
421 aaggcacggg atgacatgaa aagacattca ccagaagatc ctgaagcaac gatgactgac
481 caaggaccaa gcaaggaaaa agtgccagga atttcacaag ctgtgcaaca agatagtgcc
541 acagctgcag agacaaaaga acaagaaatt tcacaagcta tggaacaaga aggtgccaca
601 gcagcagaga cagaagaaca agaaatttca caagctatgg aacaagaagg tgccacagca
661 gcagagacag aagaacaagg acatggaggt gacacatggg actacaagag tcacgtgatg
721 accaaattcg ctgaggagga ggatgtacgt cgtagttttg aaaacactgc tgctgactgg
781 ccggaaatgc aaacgttggc tggtgctttt gattcagacc ggtggggctt ccggcctcgc
841 acggtggttc tgcacggaaa gtcaggaatt gggaaatcgg ctctagccag aaggatcgtg
901 ctgtgctggg cgcaaggtgg actctaccag ggaatgttct cctacgtctt cttcctcccc
961 gttagagaga tgcagcggaa gaaggagagc agtgtcacag agttcatctc cagggagtgg
1021 ccagactccc aggctccggt gacggagatc atgtcccgac cagaaaggct gttgttcatc
1081 attgacggtt tcgatgacct gggctctgtc ctcaacaatg acacaaagct ctgcaaagac
1141 tgggctgaga agcagcctcc gttcaccctc atacgcagtc tgctgaggaa ggtcctgctc
1201 cctgagtcct tcctgatcgt caccgtcaga gacgtgggca cagagaagct caagtcagag
1261 gtcgtgtctc cccgttacct gttagttaga ggaatctccg gggaacaaag aatccacttg
1321 ctccttgagc gcgggattgg tgagcatcag aagacacaag ggttgcgtgc gatcatgaac
1381 aaccgtgagc tgctcgacca gtgccaggtg cccgccgtgg gctctctcat ctgcgtggcc
1441 ctgcagctgc aggacgtggt gggggagagc gtcgccccct tcaaccaaac gctcacaggc
1501 ctgcacgccg cttttgtgtt tcatcagctc acccctcgag gcgtggtccg gcgctgtctc
1561 aatctggagg aaagagttgt cctgaagcgc ttctgccgta tggctgtgga gggagtgtgg
1621 aataggaagt cagtgtttga cggtgacgac ctcatggttc aaggactcgg ggagtctgag
1681 ctccgtgctc tgtttcacat gaacatcctt ctcccagaca gccactgtga ggagtactac
1741 accttcttcc acctcagtct ccaggacttc tgtgccgcct tgtactacgt gttagagggc
1801 ctggaaatcg agccagctct ctgccctctg tacgttgaga agacaaagag gtccatggag
1861 cttaaacagg caggcttcca tatccactcg ctttggatga agcgtttctt gtttggcctc
1921 gtgagcgaag acgtaaggag gccactggag gtcctgctgg gctgtcccgt tcccctgggg
1981 gtgaagcaga agcttctgca ctgggtctct ctgttgggtc agcagcctaa tgccaccacc
2041 ccaggagaca ccctggacgc cttccactgt cttttcgaga ctcaagacaa agagtttgtt
2101 cgcttggcat taaacagctt ccaagaagtg tggcttccga ttaaccagaa cctggacttg
2161 atagcatctt ccttctgcct ccagcactgt ccgtatttgc ggaaaattcg ggtggatgtc
2221 aaagggatct tcccaagaga tgagtccgct gaggcatgtc ctgtggtccc tctatggatg
2281 cgggataaga ccctcattga ggagcagtgg gaagatttct gctccatgct tggcacccac
2341 ccacacctgc ggcagctgga cctgggcagc agcatcctga cagagcgggc catgaagacc
2401 ctgtgtgcca agctgaggca tcccacctgc aagatacaga ccctgatgtt tagaaatgca
2461 cagattaccc ctggtgtgca gcacctctgg agaatcgtca tggccaaccg taacctaaga
2521 tccctcaact tgggaggcac ccacctgaag gaagaggatg taaggatggc gtgtgaagcc
2581 ttaaaacacc caaaatgttt gttggagtct ttgaggctgg attgctgtgg attgacccat
2641 gcctgttacc tgaagatctc ccaaatcctt acgacctccc ccagcctgaa atctctgagc
2701 ctggcaggaa acaaggtgac agaccaggga gtaatgcctc tcagtgatgc cttgagagtc
2761 tcccagtgcg ccctgcagaa gctgatactg gaggactgtg gcatcacagc cacgggttgc
2821 cagagtctgg cctcagccct cgtcagcaac cggagcttga cacacctgtg cctatccaac
2881 aacagcctgg ggaacgaagg tgtaaatcta ctgtgtcgat ccatgaggct tccccactgt
2941 agtctgcaga ggctgatgct gaatcagtgc cacctggaca cggctggctg tggttttctt
3001 gcacttgcgc ttatgggtaa ctcatggctg acgcacctga gccttagcat gaaccctgtg
3061 gaagacaatg gcgtgaagct tctgtgcgag gtcatgagag aaccatcttg tcatctccag
3121 gacctggagt tggtaaagtg tcatctcacc gccgcgtgct gtgagagtct gtcctgtgtg
3181 atctcgagga gcagacacct gaagagcctg gatctcacgg acaatgccct gggtgacggt
3241 ggggttgctg cactgtgcga gggactgaag caaaagaaca gtgttctgac gagactcggg
3301 ttgaaggcat gtggactgac ttctgattgc tgtgaggcac tctccttggc cctttcctgc
3361 aaccggcatc tgaccagtct aaacctggtg cagaataact tcagtcccaa aggaatgatg
3421 aagctgtgtt cggcctttgc ctgtcccacg tctaacttac agataattgg gctgtggaaa
3481 tggcagtacc ctgtgcaaat aaggaagctg ctggaggaag tgcagctact caagccccga
3541 gtcgtaattg acggtagttg gcattctttt gatgaagatg accggtactg gtggaaaaac
3601 tgaagatacg gaaacctgcc ccactcacac ccatctgatg gaggaacttt aaacgctgtt
3661 ttctcagagc aagctatgca cctgggagtt ccttctcaaa gatggagaat gatttctgat
3721 tctcacaaag ccctcaatgg tagtgattct tctgtgttca ctctacgttg gttactggat
3781 ttgaaggcta gagaccttca agtcatagga ctcagtatct gtgaaatgtc cgtcatatct
3841 cagagcatat agagggaatt aaataaacac aaagcatttg gaaaa
//