LOCUS AY149629 6090 bp mRNA linear HUM 05-SEP-2003
DEFINITION Homo sapiens death receptor interacting protein (GITA) mRNA,
complete cds.
ACCESSION AY149629
VERSION AY149629.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6090)
AUTHORS Rippe,V., Drieschner,N., Meiboom,M., Murua Escobar,H., Bonk,U.,
Belge,G. and Bullerdiek,J.
TITLE Identification of a gene rearranged by 2p21 aberrations in thyroid
adenomas
JOURNAL Oncogene 22 (38), 6111-6114 (2003)
PUBMED 12955091
REFERENCE 2 (bases 1 to 6090)
AUTHORS Rippe,V., Drieschner,N., Meiboom,M., Murua Escobar,H., Bonk,U.,
Belge,G. and Bullerdiek,J.
TITLE A gene encoding a death receptor interacting protein rearranged by
2p21 aberrations links thyroid adenomas with disturbed homeostasis
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 6090)
AUTHORS Rippe,V., Drieschner,N., Hommes,J. and Bullerdiek,J.
TITLE Direct Submission
JOURNAL Submitted (11-SEP-2002) Center for Human Genetics, University of
Bremen, Leobener Str. ZHG, Bremen 28359, Germany
FEATURES Location/Qualifiers
source 1..6090
/db_xref="H-InvDB:HIT000250822"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2p21"
/cell_line="thyroid adenoma"
gene 1..6090
/gene="GITA"
/note="gene inducing thyroid adenomas"
CDS 133..5994
/gene="GITA"
/codon_start=1
/product="death receptor interacting protein"
/protein_id="AAO46785.1"
/translation="MGVKKKKEMQVAALTICHQDLETLKSFADVEGKNLASLLLHCVQ
LTDGVSQIHYIKQIVPLLEKADKNGMCDPTIQSCLDILAGIYLSLSLKNPLKKVLASS
LNSLPDFFLPEAMHRFTSRLQEELNTTDLYSYRKVTDNISSCMENFNLGRASVNNLLK
NVLHFLQKSLIEILEENRKCAGNHIIQTQLMNDLLVGIRVSMMLVQKVQDFQGNLWKT
SDSPIWQNMCGLLSIFTKVLSDDDLLQTVQSTSGLAIILFIKTMFHPSEKIPHLISSV
LLRSVDCTSVPEWFMSSCRSLCCGDISQSAVLFLCQGTLAMLDWQNGSMGRSGEALLL
DTAHVLFTLSSQIKEPTLEMFLSRILASWTNSAIQVLESSSPSLTDSLNGNSSIVGRL
LEYVYTHWEHPLDALRHQTKIMFKNLLQMHRLTVEGADFVPDPFFVELTESLLRLEWH
IKGKYTCLGCLVECIGVEHILAIDKTIPSQILEVMGDQSLVPYASDLLETMFRNHKSH
LKSQTAESSWIDQWHETWVSPLLFILCEGNLDQKSYVIDYYLPKLLSYSPESLQYMVK
ILQTSIDAKTGQEQSFPSLGSCNSRGALGALMACLRIARAHGHLQSATDTWENLVSDA
RIKQGLIHQHCQVRIDTLGLLCESNRSTEIVSMEEMQWIQFFITYNLNSQSPGVRQQI
CSLLKKLFCRIQESSQVLYKLEQSKSKREPENELTKQHPSVSLQQYKNFMSSICNSLF
EALFPGSSYSTRFSALTILGSIAEVFHVPEGRIYTVYQLSHDIDVGRFQTLMECFTST
FEDVKILAFDLLMKLSKTAVHFQDSGKLQGLFQAALELSTSTKPYDCVTASYLLNFLI
WQDALPSSLSAYLTQQVACDNGDRPAAVVERNTLMVIKCLMENLEEEVSQAENSLLQA
AAAFPMYGRVHCITGALQKLSLNSLQLVSEWRPVVEKLLLMSYRLSTVVSPVIQSSSP
EGLIPMDTDSESASRLQMILNEIQPRDTNDYFNQAKILKEHDSFDMKDLNASVVNIDT
STEIKGKEVKTCDVTAQMVLVCCWRSMKEVALLLGMLCQLLPMQPVPESSDGLLTVEQ
VKEIGDYFKQHLLQSRHRGAFELAYTGFVKLTEVLNRCPNVSLQKLPEQWLWSVLEEI
KCSDPSSKLCATRRSAGIPFYIQALLASEPKKGRMDLLKITMKELISLAGPTDDIQST
VPQVHALNILRALFRDTRLGENIIPYVADGAKAAILGFTSPVWAVRNSSTLLFSALIT
RIFGVKRAKDEHSKTNRMTGREFFSRFPELYPFLLKQLETVANTVDSDMGEPNRHPSM
FLLLLVLERLYASPMDGTSSALSMGPFVPFIMRCGHSPVYHSREMAARALVPFVMIDH
IPNTIRTLLSTLPSCTDQCFRQNHIHGTLLQVFHLLQAYSDSKHGTNSDFQHELTDIT
VCTKAKLWLAKRQNPCLVTRAVYIDILFLLTCCLNRSAKDNQPVLESLGFWEEVRGII
SGSELITGFPWAFKVPGLPQYLQSLTRLAIAAVWAAAAKSGERETNVPISFSQLLESA
FPEVRSLTLEALLEKFLAAASGLGEKGVPPLLCNMGEKFLLLAMKENHPECFCKILKI
LHCMDPGEWLPQTEHCVHLTPKEFLIWTMDIASNERSEIQSVALRLASKVISHHMQTC
VENRELIAAELKQWVQLVILSCEDHLPTESRLAVVEVLTSTTPLFLTNPHPILELQDT
LALWKCVLTLLQSEEQAVRDAATETVTTAMSQENTCQSTEFAFCQVDASIALALALAV
LCDLLQQWDQLAPGLPILLGWLLGESDDLVACVESMHQVEEDYLFEKAEVNFWAETLI
FVKYLCKHLFCLLSKSGWRPPSPEMLCHLQRMVSEQCHLLSQFFRELPPAAEFVKTVE
FTRLRIQEERTLACLRLLAFLEGKEGEDTLVLSVWDSYAESRQLTLPRTEAAC"
BASE COUNT 1649 a 1298 c 1416 g 1727 t
ORIGIN
1 agtcgaccgt ggaccgcgct gcgagcctcg gagacgccgt agaaggagac ctgcttccgg
61 gactggacca ggcgcctgcg actcttctca gacgccgacg tgcacgagtg actactatta
121 attctattta aaatgggtgt aaagaagaag aaagaaatgc aagttgctgc gctgaccatt
181 tgccatcagg accttgaaac tttgaaatct tttgctgatg tggaagggaa aaatctagct
241 tctttgctgt tacattgtgt gcaactcacg gatggagtgt cacaaatcca ttatattaaa
301 cagattgtgc ctctgctgga gaaagcagat aaaaatggca tgtgtgatcc cactattcaa
361 agttgtttgg atatcttagc aggcatttat ctttctttga gtctaaagaa tcccttgaag
421 aaagtattgg caagctcact aaatagcctg cctgattttt ttctacctga ggctatgcac
481 cgttttactt ctcgtcttca ggaagaattg aatactactg acttatactc ttacaggaaa
541 gttactgaca atatttcttc ctgtatggag aactttaact tgggtagagc aagtgttaat
601 aatctgctta aaaatgtgct tcattttctg cagaagagtt taattgaaat cctggaagaa
661 aatagaaaat gtgctggaaa tcatattatt caaacacagt tgatgaatga cttactggta
721 ggcattagag tttcaatgat gttagtacag aaagtacaag atttccaggg aaatctttgg
781 aagacttccg attctcccat atggcaaaat atgtgtggat tgctgagtat ttttaccaag
841 gttttaagcg atgatgatct gttacagact gtacagagca catctggatt agctattatt
901 ctttttatta agactatgtt tcacccgtct gaaaagattc ctcatttgat tagcagtgtg
961 ctgcttcgtt cagtggactg caccagtgtc cccgagtggt ttatgagcag ctgcaggagc
1021 ctctgttgtg gtgacatctc tcagtcagct gtcttattcc tctgtcaggg gacacttgcc
1081 atgttggact ggcagaacgg aagcatgggt cggagtgggg aggccctgct cttggatact
1141 gcacatgttt tgttcacctt gagttcacag attaaagagc caacgctgga aatgtttctg
1201 tctagaatct tagcatcctg gactaattca gccatacaag tccttgaatc aagttccccg
1261 agcctaacgg acagcctgaa tgggaattca agtatagttg ggagactttt ggaatatgtc
1321 tatacccatt gggaacatcc attggatgct ctgagacacc aaaccaaaat catgttcaaa
1381 aaccttctcc aaatgcaccg gctcactgtg gaaggtgcag atttcgtccc tgatcctttc
1441 tttgtggaat tgactgagag tcttttacga ttggaatggc atattaaagg aaagtacacg
1501 tgccttggtt gtttggtaga gtgcatagga gttgaacata ttttggctat agataaaact
1561 attccatctc aaatcttaga ggtgatggga gaccagtcat tggtacctta tgcaagtgac
1621 ctcttggaaa ccatgtttag aaatcataag agtcatttga aatcccagac tgctgagagt
1681 tcttggattg accagtggca tgagacttgg gtttctcctc tcctttttat attgtgtgaa
1741 ggaaacttgg atcaaaaatc ttacgtgatt gattattact tgccaaaatt attaagttac
1801 agccctgaaa gcttacagta catggtaaag attcttcaga cttctattga tgctaaaact
1861 ggacaagagc aatctttccc atccttaggg tcttgtaata gcaggggggc tctgggagct
1921 ttgatggcat gtctgcgaat agctagagct catggacatc ttcagtctgc aactgatacc
1981 tgggagaacc tcgtgtctga tgcaagaata aagcaaggct taattcatca gcattgccaa
2041 gtaaggatag atacattagg cttgctttgt gaaagtaatc ggagcacaga aattgtttcc
2101 atggaagaaa tgcagtggat tcagttcttt attacataca atcttaacag ccagtctcca
2161 ggagtgcggc aacagatctg ttctcttctt aaaaagttgt tttgtaggat acaggaaagt
2221 tctcaggtac tttataaatt ggagcagagt aaatccaaac gtgaaccaga gaatgagtta
2281 accaaacagc acccttctgt ttctttacag cagtataaga atttcatgtc atccatttgt
2341 aacagtcttt ttgaagcatt gtttcctgga tcttcctact cgactagatt ttcagcttta
2401 accattttag gttcaatagc tgaagttttt catgtcccag aaggcagaat ttatacagta
2461 tatcagctga gtcatgatat tgatgttggt cgtttccaaa cactaatgga atgttttacc
2521 agcacttttg aagacgtgaa aattttagca tttgatcttc tgatgaagtt atcaaaaaca
2581 gctgtacatt ttcaggattc ggggaaactg caaggcttat ttcaggcagc attggagctc
2641 agcacaagca ccaaaccata cgactgtgtg acagcttcct acctgctgaa cttcttaatc
2701 tggcaggatg ctctaccgtc atccttgtct gcctacttaa ctcagcaagt tgcatgtgat
2761 aatggagata ggcctgctgc tgtggtggaa aggaacacat taatggttat caaatgcttg
2821 atggaaaatc ttgaggaaga agtatctcag gctgaaaatt ctctgcttca ggcagcagca
2881 gcatttccaa tgtatgggcg agtccactgt ataacaggag ctttgcagaa gttatctcta
2941 aacagcctgc agttggtgag cgagtggaga cctgtggtag agaagctcct tttgatgtcc
3001 tacaggcttt ccactgtggt gtctccagtc attcagagct catcccctga aggcctcatc
3061 ccaatggaca ctgattcaga gtcagcaagc cgcttacaga tgattctgaa tgagattcag
3121 cctcgagata ctaatgatta ttttaaccaa gccaaaatat tgaaagaaca tgatagcttt
3181 gatatgaagg acttgaatgc tagtgtggtg aatattgata cttctacaga aatcaaaggt
3241 aaagaagtaa aaacatgtga tgtaactgcg cagatggtgc tggtatgttg ttggagaagt
3301 atgaaggaag ttgctttact tttaggcatg ttgtgccagc ttctgcccat gcagcctgtg
3361 ccagaatctt ctgatggatt attgacggtg gagcaggtaa aagaaatagg agattacttt
3421 aaacaacacc ttttgcagtc caggcacaga ggagcatttg aattggctta tactggtttt
3481 gtgaaactca ctgaagtact aaacaggtgc ccaaatgtga gtctgcaaaa gctgccagaa
3541 cagtggctat ggagtgtttt agaggaaatt aaatgcagtg atccttcatc taaactctgt
3601 gctacaaggc gcagtgctgg aattcctttc tacatacagg cactgttggc atctgaacca
3661 aagaaaggca gaatggattt gttgaaaata acaatgaaag agttaatctc tttggctggg
3721 cctacagatg acatacagag tacagtcccc caggttcatg ctttaaatat ccttagagca
3781 ttgttcagag atacgcgcct gggagaaaat attattcctt atgttgctga tggagctaag
3841 gctgcaattc tgggttttac atcaccggtc tgggcagtgc gaaattcatc cacacttctc
3901 tttagtgcct tgatcacaag aatttttgga gttaaaaggg caaaggatga acattccaaa
3961 acaaatagaa tgacagggag agagtttttc tctcgtttcc cagaactcta tccttttctt
4021 ctcaaacagt tggaaactgt agccaataca gtagacagtg atatgggaga accaaatcgt
4081 catccaagca tgtttctctt acttttggtg ttggagagac tctacgcttc cccgatggat
4141 ggtacttctt ctgctctcag catgggacct tttgttccct tcattatgag gtgtggtcac
4201 tcacctgtct accactcccg tgaaatggca gctcgtgcct tggtcccatt tgttatgata
4261 gatcacattc ctaataccat tcgaactctg ttgtccacac tccccagctg cactgaccag
4321 tgtttccggc aaaaccacat tcatgggaca cttctccagg tttttcattt gttgcaagcc
4381 tactcagact ccaaacacgg aacgaattca gacttccagc acgagctgac tgacatcact
4441 gtttgtacca aagccaaact ctggctggcc aagaggcaaa atccatgttt ggtgaccaga
4501 gctgtatata ttgatattct cttcctattg acttgctgcc tcaacagatc tgcaaaggac
4561 aaccagccag ttctggagag tcttggcttc tgggaggaag tcagagggat tatctcagga
4621 tcagagctga taacgggatt cccttgggcc ttcaaggtgc caggcctgcc ccagtacctc
4681 cagagcctca ccagactagc cattgctgca gtgtgggccg cggcagccaa gagtggagag
4741 cgggagacga atgtccccat ctctttctct cagctgttag aatctgcctt ccctgaagtg
4801 cgctcactaa cactggaagc cctcttggaa aagttcttag cagcagcctc tggacttgga
4861 gagaagggcg tgccaccctt gctgtgcaac atgggagaga agttcttatt gttggccatg
4921 aaggaaaatc acccagaatg cttctgcaag atactgaaaa ttctccactg catggaccct
4981 ggtgagtggc ttccccagac ggagcactgt gtccatctga ccccaaagga gttcttgatc
5041 tggacgatgg atattgcttc caatgaaaga tctgaaattc agagtgtagc tctgagactt
5101 gcttccaaag tcatttccca ccacatgcag acatgtgtgg agaacaggga attgatagct
5161 gctgagctga agcagtgggt tcagctggtc atcttgtcat gtgaagacca tcttcctaca
5221 gagtctaggc tggccgtcgt tgaagtcctc accagtacta caccactttt cctcaccaac
5281 ccccatccta ttcttgagtt gcaggataca cttgctctct ggaagtgtgt ccttaccctt
5341 ctgcagagtg aggagcaagc tgttagagat gcagccacgg aaaccgtgac aactgccatg
5401 tcacaagaaa atacctgcca gtcaacagag tttgccttct gccaggtgga tgcctccatc
5461 gctctggccc tggccctggc cgtcctgtgt gatctgctcc agcagtggga ccagttggcc
5521 cctggactgc ccatcctgct gggatggctg ttgggagaga gtgatgacct cgtggcctgt
5581 gtggagagca tgcatcaggt ggaagaagac tacctgtttg aaaaagcaga agtcaacttt
5641 tgggccgaga ccctgatctt tgtgaaatac ctctgcaagc acctcttctg tctcctctca
5701 aagtccggct ggcgtccccc aagccctgag atgctctgtc accttcaaag gatggtgtca
5761 gagcagtgcc acctcctgtc tcagttcttc agagagcttc caccagctgc tgagtttgtg
5821 aagacagtgg agttcacaag actacgcatt caagaggaaa ggactttggc ttgcttgagg
5881 ctgctggcct ttttggaagg aaaggaaggg gaagacaccc tagttctcag tgtttgggac
5941 tcttatgcag aatcgaggca gttaactctt ccaagaacag aagcggcatg ttgaagaaaa
6001 tctgggggat tgggatgggg gtatgtgtgg atttttcctc cactaaatct gcaggaaaca
6061 tgttgaacat aaattcaaaa attttatccc
//