LOCUS AY144493 2794 bp mRNA linear HUM 27-MAR-2003
DEFINITION Homo sapiens ezrin-binding protein PACE-1 mRNA, complete cds;
alternatively spliced.
ACCESSION AY144493
VERSION AY144493.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2794)
AUTHORS Sullivan,A., Uff,C.R., Isacke,C.M. and Thorne,R.F.
TITLE PACE-1, a novel protein that interacts with the C-terminal domain
of ezrin
JOURNAL Exp. Cell Res. 284 (2), 224-238 (2003)
PUBMED 12651155
REFERENCE 2 (bases 1 to 2794)
AUTHORS Sullivan,A., Uff,C.R., Isacke,C.M. and Thorne,R.F.
TITLE Direct Submission
JOURNAL Submitted (26-AUG-2002) Breakthrough Center, Institute of Cancer
Research, 237 Fulham Rd., London SW3 6JB, UK
FEATURES Location/Qualifiers
source 1..2794
/db_xref="H-InvDB:HIT000084738"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1q23.3-q23.4"
/note="derived from dbEST clone H65154"
CDS 53..2281
/note="alternatively spliced"
/codon_start=1
/product="ezrin-binding protein PACE-1"
/protein_id="AAN41656.1"
/translation="MGSENSALKSYTLREPPFTLPSGLAVYPAVLQDGKFASVFVYKR
ENEDKVNKAAKHLKTLRHPCLLRFLSCTVEADGIHLVTERVQPLEVALETLSSAEVCA
GIYDILLALIFLHDRGHLTHNNVCLSSVFVSEDGHWKLGGMETVCKVSQATPEFLRSI
QSIRDPASIPPEEMSPEFTTLPECHGHARDAFSFGTLVESLLTILNEQVSADVLSSFQ
QTLHSTLLNPIPKCRPALCTLLSHDFFRNDFLEVVNFLKSLTLKSEEEKTEFFKFLLD
RVSCLSEELIASRLVPLLLNQLVFAEPVAVKSFLPYLLGPKKDHAQGETPCLLSPALF
QSRVIPVLLQLFEVHEEHVRMVLLSHIEAYVEHFTQEQLKKVILPQVLLGLRDTSDSI
VAITLHSLAVLVSLLGPEVVVGGERTKIFKRTAPSFTKNTDLSLEDSPMCVVCSHHSQ
ISPILENPFSSIFPKCFFSGSTPINSKKHIQRDYYNTLLQTGDPFSQPIKFPINGLSD
VKNTSEDSENFPSSSKKSEEWPDWSEPEEPENQTVNIQIWPREPCDDVKSQCTTLDVE
ESSWDDCEPSSLDTKVNPGGGITATKPVTSGEQKPIPALLSLTEESTPWKSSLPRKIS
LVQRGDDADQIEPPKVSSQERPLKVPSELGLGEEFTIQVKKKPVKDPEMDWFADMIPE
IKPSAAFLILPELRTEMVPKKDDVSPVMQFSSKFAAAEITEGEAEGWEEEGELNWEDN
NW"
exon 1364..1525
/note="exon 12; absent in alternatively spliced form in
GenBank Accession Number AF540957"
BASE COUNT 786 a 586 c 644 g 778 t
ORIGIN
1 agatctgctt ggctttgagg aagagtggca gtactgcctc actgcataag ggatgggatc
61 agagaacagt gctttaaaga gctatacact gagagaacca ccatttacct taccctctgg
121 acttgctgtt tatcccgctg tactgcaaga tggcaaattt gcttcagttt ttgtgtataa
181 gagagaaaat gaagacaagg ttaataaagc tgccaagcat ttgaagacac ttcgtcaccc
241 ttgcttgcta agatttttat cttgtactgt ggaagcggat ggcattcatc ttgtcactga
301 gcgagtacag cccctggaag tggctttgga aacattgtct tctgcagagg tctgtgctgg
361 gatctatgac atattgctgg ctcttatctt ccttcatgac agaggacacc taacacacaa
421 taatgtctgt ttatcatctg tgtttgtgag tgaagatgga cactggaagc taggaggaat
481 ggaaactgtt tgtaaagttt ctcaggccac accagagttt ctgaggagta ttcagtcaat
541 aagagaccca gcatctatcc ctcctgaaga gatgtctcca gaattcacaa ctctcccaga
601 gtgtcatgga catgcccggg atgccttttc atttggaaca ttggtggaaa gtttgctcac
661 aatcttaaat gaacaggttt cagcggatgt tctctccagc tttcaacaga ccttgcactc
721 aactttgctg aatcccattc caaaatgtcg gccagcgctc tgcaccttac tatctcatga
781 cttcttcaga aatgattttc tggaagttgt gaatttcttg aaaagtttaa cattgaagag
841 tgaagaggag aaaacggaat tctttaaatt tctgctggac agagtcagct gcttgtcaga
901 ggaattgata gcttcaaggt tggtgcctct tctgcttaat cagttggtgt ttgcagagcc
961 agtggctgtt aagagttttc ttccttatct gcttggcccc aaaaaagatc atgcgcaggg
1021 agaaactcct tgcttgctct caccagccct gttccagtca cgggtgatcc ccgtgcttct
1081 ccagttgttt gaagttcatg aagagcatgt gcggatggtg ctgctgtctc acatcgaggc
1141 ctacgtggag cacttcactc aggagcagct gaagaaagtc atcttgccac aggttttgct
1201 gggcctgcgt gatactagcg attccattgt ggcaattact ctgcatagcc tagcagtgct
1261 ggtctctctg cttggaccag aggtggttgt gggaggagaa cgaaccaaga tcttcaaacg
1321 cactgcccca agttttacta aaaatactga cctttctcta gaagattctc ctatgtgtgt
1381 cgtctgcagc catcacagtc agatctcgcc aatcttggag aaccccttct ctagcatatt
1441 ccctaaatgt ttcttttctg gcagcacgcc catcaacagc aagaagcaca tacagcgaga
1501 ttactacaat actcttttac agacaggcga tccattttct cagcctatta aatttcccat
1561 aaatggactc tcagatgtaa aaaatacttc ggaggacagt gaaaacttcc catcaagttc
1621 taaaaagtct gaggagtggc ctgactggag tgaacctgag gagcctgaaa atcaaactgt
1681 caacatacag atttggccta gagaaccttg tgatgatgtc aagtcccagt gcactacctt
1741 ggatgtggaa gagtcatctt gggatgactg cgagcccagc agcttagata ctaaagtaaa
1801 cccaggaggt ggaatcactg ctacaaaacc tgttacctca ggggagcaga agcctattcc
1861 tgctttgctt tcactcactg aagagtctac gccttggaaa tcaagcttac cccgaaagat
1921 tagccttgta caaagggggg atgacgcaga ccaaatcgag ccgccaaaag tgtcatcaca
1981 agaaaggccc cttaaggttc catcagaact tggtttagga gaggaattca ccattcaagt
2041 aaaaaagaag ccagtaaaag atcctgagat ggattggttt gctgatatga tcccagaaat
2101 taagccttct gctgcttttc ttatattacc tgaactgagg acagaaatgg tcccaaaaaa
2161 ggatgatgtc tccccagtga tgcagttttc ctcaaaattt gctgcagcag aaattactga
2221 gggagaggct gaaggctggg aagaagaagg ggagctgaac tgggaagata ataactggtg
2281 acaatggatg tgagttaaac tttgggaaaa aggattccct ttttttaaaa aaaatcaata
2341 cctcaaaagc aggctttggg acaagaaaac cccaaagtgg cctgcttttc ccatcccagg
2401 agctcattat ccagtctgtg ccaactgaag taggagactg actgtgagtg ctggctaaaa
2461 gccctgggtg gtgaggctca cagtactggt ttccaggagg aagagccttt gtgcatttga
2521 ctgaggccag tttctatgaa gagcaagtag ctgaggagag gtcgaattta ctgctttttc
2581 caggacaatt ctggaagtaa agaaaatgta attcaagctg gttagcttaa ttttgtgcca
2641 ttctttaaca taagagtaag ctctattatg aaatacaact ttaaaaaatt ttagctataa
2701 attatataaa tgattttaaa ttgctgaggt ttccttaggc agcttattta tttgtttaca
2761 gttagactat ctgagtaaat ggttctttgt ggac
//