LOCUS AY130459 4280 bp mRNA linear HUM 05-OCT-2002
DEFINITION Homo sapiens fibulin 2 (FBLN2) mRNA, complete cds.
ACCESSION AY130459
VERSION AY130459.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4280)
AUTHORS Li,D., Marian,A.J. and Roberts,R.
TITLE Identification of a novel alternatively spliced isoform of human
fibulin-2 gene abundantly expressed in heart and genetic evaluation
in patients with ARVD
JOURNAL (in) ? (Ed.);
ABSTRACTS OF THE 52ND ANNUAL MEETING OF THE AMERICAN SOCIETY OF
HUMAN GENETICS.: 323;
(2002)
REFERENCE 2 (bases 1 to 4280)
AUTHORS Li,D. and Roberts,R.
TITLE Direct Submission
JOURNAL Submitted (10-JUL-2002) Medicine, Baylor College of Medicine, One
Baylor Plaza 533D, Houston, TX 77030, USA
FEATURES Location/Qualifiers
source 1..4280
/db_xref="H-InvDB:HIT000084627"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="3"
/map="3p25-p24"
gene 1..4280
/gene="FBLN2"
CDS 70..3765
/gene="FBLN2"
/codon_start=1
/product="fibulin 2"
/protein_id="AAN05436.1"
/translation="MVLLWEPAGAWLALGLALALGPSVAAAAPRQDCTGVECPPLENC
IEEALEPGACCATCVQQGCACEGYQYYDCLQGGFVRGRVPAGQSYFVDFGSTECSCPP
GGGKISCQFMLCPELPPNCIEAVVVADSCPQCGQVGCVHAGHEYAAGHTVHLPPCRAC
HCPDAGGELICYQLPGCHGNFSDAEEGDPERHYEDPYSYDQEVAEVEAATALGGEVQA
GAVQAGAGGPPAALGGGSQPLSTIQAPPWPAVLPRPTAAAALGPPAPVQAKARRVTED
SEEEEEEEEEREEMAVTEQLAAGGHRGLDGLPTTAPAGPSLPIQEERAEAGARAEAGA
RPEENLILDAQATSRSTGPEGVTHAPSLGKAALVPTQAVPGSPRDPVKPSPHNILSTS
LPDAAWIPPTREVPRKPQVLPHSHVEEDTDPNSVHSIPRSSPEGSTKDLIETCCAAGQ
QWAIDNDECLEIPESGTEDNVCRTAQRHCCVSYLQEKSCMAGVLGAKEGETCGAEDND
SCGISLYKQCCDCCGLGLRVRAEGQSCESNPNLGYPCNHVMLSCCEGEEPLIVPEVRR
PPEPAAAPRRVSEAEMAGREALSLGTEAELPNSLPGDDQDECLLLPGELCQHLCINTV
GSYHCACFPGFSLQDDGRTCRPEGHPPQPEAPQEPALKSEFSQVASNTIPLPLPQPNT
CKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTL
GSFYCVNHTVLCADGYILNAHRKCVGKNECVTDLHTCSRGEHCVNTLGSFHCYKALTC
EPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGFLQDPEGNCV
DINECTSLSEPCRPGFSCINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVH
RCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTCENTLGSYR
CSCASGFLLAADGKRCEDVNECEAQRCSQECANIYGSYQCYCRQGYQLAEDGHTCTDI
DECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSCKDVDECALGTHNCSEAET
CHNIQGSFRCLRFECPPNYVQVSKTKCERTTCHDFLECQNSPARITHYQLNFQTGLLV
PAHIFRIGPAPAFTGDTIALNIIKGNEEGYFGTRRLNAYTGVVYLQRAVLEPRDFALD
VEMKLWRQGSVTTFLAKMHIFFTTFAL"
BASE COUNT 846 a 1313 c 1321 g 800 t
ORIGIN
1 tcgcggccgc cgagcgcagt gccccgcggg tcttacagga gaggggaccg tcctgggctg
61 gcctggacca tggtgctgct ctgggagcct gcaggagcct ggcttgctct gggcctggcc
121 ctggccctgg gccccagcgt ggccgcagct gcccctcggc aggactgcac gggcgtggag
181 tgcccgccgc tggagaactg cattgaggag gcgctggagc cgggtgcctg ctgtgccacg
241 tgtgtgcagc agggctgcgc ctgcgagggc taccagtact atgactgcct acagggtggc
301 ttcgtgcgcg gccgcgtgcc cgccggtcag tcctattttg tggacttcgg gagcactgag
361 tgctcctgcc caccaggcgg cggcaagatc agctgccagt tcatgctgtg cccggagctg
421 ccgcccaact gcatcgaggc tgtagtggtg gctgacagct gcccacagtg cggccaggtg
481 ggctgcgtcc acgcgggcca cgagtacgcc gctggccaca ctgttcacct gccgccctgc
541 cgggcctgcc actgccctga cgccggtgga gagctcatct gctaccagct ccccggttgc
601 cacgggaact tctcagatgc cgaggagggt gaccccgagc gacactacga agacccctac
661 agctatgacc aggaggtggc cgaggtggaa gcagcaacag ccctgggggg tgaggtccag
721 gcgggtgcag tccaggcagg cgcagggggc cccccagctg ctctgggagg tgggagtcag
781 ccactgtcca ccatccaggc acccccctgg ccagctgtcc tccccaggcc cacagcggct
841 gctgccctgg gtcccccagc cccagtgcag gccaaagcta ggagagtgac cgaggacagt
901 gaggaggaag aagaggagga ggaggagaga gaggaaatgg ctgtcactga gcagctggca
961 gcaggtggcc acagggggct ggatgggctg cccactacag ccccagctgg acccagtctt
1021 cctatccagg aggagagggc agaagctggg gcaagggcag aagctggggc aaggcctgaa
1081 gagaacctca tcctggatgc ccaagccacg tcccgcagca ctgggccgga gggcgtgacg
1141 catgcaccga gcctgggcaa ggctgctctc gtcccaactc aggccgtgcc tggctctccc
1201 agggacccag tcaagcccag cccccacaac atcctgtcca catcactgcc tgatgcagcc
1261 tggatcccac ccacccgaga agtgcccagg aagccgcaag ttctgcccca ttcccacgtg
1321 gaggaggaca cagaccccaa ctctgtccat tctatcccca gaagtagccc tgaaggctcc
1381 accaaggacc tgatcgagac ttgctgcgca gccggacagc agtgggccat tgacaatgac
1441 gagtgcctgg agatccctga gagtggcact gaggacaacg tctgcaggac agcccagagg
1501 cactgctgtg tctcctactt gcaggagaag agctgcatgg ccggcgtcct gggagccaag
1561 gagggtgaga cctgtggggc tgaggacaac gacagctgcg gcatctccct gtacaagcaa
1621 tgctgtgact gctgtggcct gggcctccgc gtgcgggccg agggccagtc gtgtgagtcc
1681 aatcctaacc tgggctatcc ctgcaatcat gtcatgctct cctgctgtga gggtgaagag
1741 cctctcatag tacctgaggt tcgccgacct ccagagcccg cagctgcacc acggagagtt
1801 tcagaggcag agatggcggg ccgagaggcc ctgtcactgg gcacagaggc cgagctgccg
1861 aacagcctgc cgggcgatga ccaggatgag tgccttctcc tcccgggaga gctgtgccag
1921 cacctttgca tcaatactgt gggttcttac cactgtgcct gctttcctgg cttctcactg
1981 caggacgatg gccgcacttg ccgcccagag ggtcaccctc cacagccgga agccccacag
2041 gagcctgcac tgaagtcaga attttcccag gtggcctcta acaccatccc gctgccactg
2101 ccgcagccca atacctgcaa agacaatgga ccctgcaagc aggtgtgcag cactgttggg
2161 ggctcagcca tatgctcctg ttttcccggc tatgccatca tggcggatgg cgtgtcctgt
2221 gaagaccaag acgagtgcct gatgggtgct cacgattgta gccggcgaca gttctgtgtg
2281 aacaccctgg gatccttcta ctgtgtcaac cacacagtgc tctgtgccga tggctatatc
2341 ctcaatgcgc acaggaagtg cgtgggtaag aacgagtgtg tgacggacct gcacacgtgc
2401 agccggggcg agcactgtgt gaacacactg ggctccttcc actgctacaa ggcactcacc
2461 tgtgagccag gctatgccct caaggatggc gagtgcgaag acgtggatga gtgtgcgatg
2521 ggcacgcaca cctgccagcc gggcttcttg tgccagaaca ccaagggctc cttctactgc
2581 caggccaggc agcgctgcat ggatggcttc ctgcaggatc ctgaaggcaa ctgtgtggac
2641 atcaacgagt gcacgtcact gtccgagcca tgtcggccag gcttcagctg catcaacacg
2701 gtgggctcct acacgtgcca gaggaacccg ctgatctgcg cgcgcggcta ccacgccagc
2761 gatgatgggg ccaagtgtgt ggacgtgaat gagtgtgaga caggtgtgca ccgctgcggt
2821 gagggccaag tgtgccacaa cctccctggc tcctaccgct gtgactgcaa agccggcttt
2881 cagcgggatg ccttcggccg gggctgcatc gacgtgaatg agtgctgggc ctcgccaggc
2941 cgcctgtgcc agcacacgtg tgagaacaca ctcggctcct accgctgttc ctgcgcctcc
3001 gggttcctgc tagcagcgga cggcaagcgc tgtgaagacg tgaatgagtg tgaggcccag
3061 cgctgcagcc aggagtgtgc caacatctat ggctcctacc agtgctactg ccgccagggc
3121 taccagctgg ctgaggatgg gcacacctgc acagacatcg acgagtgtgc tcaaggcgcc
3181 ggcatcctct gcaccttccg ctgtctcaac gtgccaggga gctaccagtg tgcatgccct
3241 gagcagggct acaccatgac ggccaacggg aggtcctgca aggacgtgga tgagtgtgca
3301 ctgggcaccc acaactgttc cgaggctgag acctgccaca acatccaggg tagcttccgc
3361 tgcctgcgct tcgagtgtcc tcccaactat gtccaagtct ccaaaacgaa gtgcgagcgc
3421 accacgtgcc atgacttcct ggagtgccag aactcgccag cgcgcatcac gcactaccag
3481 ctcaacttcc agacgggcct cctggtgcct gcgcatatct tccgcattgg ccccgcgcca
3541 gccttcacgg gggacaccat cgccctgaac atcatcaagg gcaatgagga gggctacttt
3601 ggcacgcgca ggctcaatgc ctacacgggt gtggtctacc tgcagcgggc cgtgctggag
3661 ccccgggact ttgccctgga cgtggagatg aagctctgga ggcagggctc cgtcaccacc
3721 ttcctggcca agatgcacat cttcttcacc acctttgccc tgtgaggtgc cagcacgggc
3781 cacctgcggg tgtggcgcag ccagggctca cactgcgtgg gagggactgg gtcactattg
3841 tggtttttac tataactttg taaattaact taattttgct gacttgactc ctgtggcttc
3901 tggacccctc ctctgccccg caggaggaag ttccacggca ggtggtgcgt tcccatgtag
3961 gcaccaagtg gaagcttgca cggtgggcca cggccgtggc gggtgccctg tgggtgaggc
4021 tgggtgatga cctgaggacc agagacacgc gaccatgttg gggctcttgg actcctctgg
4081 atgacccgtc cccaaacgtt gacattccat ttcatgttcc actgtgatta acttcttttc
4141 ttttttaaaa aatcatttta aagttttttg tttaactata aagtagtaca tgtacattat
4201 ataaaaaaaa agttcaacta gtatgaaagg gttataaagt aacagaggaa aacgcctctt
4261 ggtcccttta aaaaaaaaaa
//