LOCUS AY129949 3276 bp mRNA linear HUM 26-JUN-2003
DEFINITION Homo sapiens cAMP-specific phosphodiesterase 8B3 (PDE8B3) mRNA,
complete cds; alternatively spliced.
ACCESSION AY129949
VERSION AY129949.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3276)
AUTHORS Hayashi,M., Shimada,Y., Nishimura,Y., Hama,T. and Tanaka,T.
TITLE Genomic organization, chromosomal localization, and alternative
splicing of the human phosphodiesterase 8B gene
JOURNAL Biochem. Biophys. Res. Commun. 297 (5), 1253-1258 (2002)
PUBMED 12372422
REFERENCE 2 (bases 1 to 3276)
AUTHORS Hayashi,M. and Tanaka,T.
TITLE Direct Submission
JOURNAL Submitted (09-JUL-2002) Molecular and Cellular Pharmacology, Mie
University School of Medicine, 2-174, Edobashi, Tsu, Mie 514-8507,
Japan
FEATURES Location/Qualifiers
source 1..3276
/db_xref="H-InvDB:HIT000250761"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..3276
/gene="PDE8B3"
CDS 46..2412
/gene="PDE8B3"
/note="HSPDE8B3; lacks exons 8, 9 and 10; alternatively
spliced"
/codon_start=1
/product="cAMP-specific phosphodiesterase 8B3"
/protein_id="AAN71724.1"
/translation="MGCAPSIHVSQSGVIYCRDSDESSSPRQTTSVSQGPAAPLPGLF
VQTDAADAIPPSRASGPPSVARVRRARTELGSGSSAGSAAPAATTSRGRRRHCCSSAE
AETQTCYTSVKQVSSAEVRIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCN
IARTPESALECFLDKHHEIIVIDHRQTQNFDAEAVCRSIRATNPSEHTVILAVVSRVS
DDHEEASVLPLLHAGFNRRFMENSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALD
HCHEAIEITSDDHVIQIHKIHRDSGDNSQTEPHSFRYKNRRKESIDVKSISSRGSDAP
SLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLEILRTTELYS
PQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLAMPITINDVPPCI
SQLLDNEESWDFNIFELEAITHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAWFQVIE
ANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHPGRT
NSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQAII
DMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPAGKNFPENQILIKRMMIKC
ADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFI
DYFITDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDS"
BASE COUNT 899 a 825 c 786 g 766 t
ORIGIN
1 gcggccgcgg gcgcgggcgg gcgcgcgggg gagcccggcc gagggatggg ctgcgccccc
61 agcatccatg tctcgcagag cggcgtgatc tactgccggg actcggacga gtccagctcg
121 ccccgccaga ccaccagcgt gtcgcagggc ccggcggcac ccctgcccgg cctcttcgtc
181 cagaccgacg ccgccgacgc catccccccg agccgcgcgt cgggaccccc cagcgtagcc
241 cgcgtccgca gggcccgcac cgagctgggc agcggtagca gcgcgggttc cgcagccccc
301 gccgcgacca ccagcagggg ccggaggcgc cactgctgca gcagcgccga ggccgagact
361 cagacctgct acaccagcgt gaagcaggtg tcttctgcgg aggtgcgcat cgggcccatg
421 agactgacgc aggaccctat tcaggttttg ctgatctttg caaaggaaga tagtcagagc
481 gatggcttct ggtgggcctg cgacagagct ggttatagat gcaatattgc tcggactcca
541 gagtcagccc ttgaatgctt tcttgataag catcatgaaa ttattgtaat tgatcataga
601 caaactcaga acttcgatgc agaagcagtg tgcaggtcga tccgggccac aaatccctcc
661 gagcacacgg tgatcctcgc agtggtttcg cgagtatcgg atgaccatga agaggcgtca
721 gtccttcctc ttctccacgc aggcttcaac aggagattta tggagaatag cagcataatt
781 gcttgctata atgaactgat tcaaatagaa catggggaag ttcgctccca gttcaaatta
841 cgggcctgta attcagtgtt tacagcatta gatcactgtc atgaagccat agaaataaca
901 agcgatgacc acgtgattca gattcacaag attcatcgtg attcaggaga taattctcag
961 acagagcctc attcattcag atataagaac aggaggaaag agtccattga cgtgaaatcg
1021 atatcatctc gaggcagtga tgcaccaagc ctgcagaatc gtcgctatcc gtccatggcg
1081 aggatccact ccatgaccat cgaggctccc atcacaaagg ttataaatat aatcaatgca
1141 gcccaagaaa acagcccagt cacagtagcg gaagccttgg acagagttct agagatttta
1201 cggaccacag aactgtactc ccctcagctg ggtaccaaag atgaagatcc ccacaccagt
1261 gatcttgttg gaggcctgat gactgacggc ttgagaagac tgtcaggaaa cgagtatgtg
1321 tttactaaga atgtgcacca gagtcacagt caccttgcaa tgccaataac catcaatgat
1381 gttccccctt gtatctctca attacttgat aatgaggaga gttgggactt caacatcttt
1441 gaattggaag ccattacgca taaaaggcca ttggtttatc tgggcttaaa ggtcttctct
1501 cggtttggag tatgtgagtt tttaaactgt tctgaaacca ctcttcgggc ctggttccaa
1561 gtgatcgaag ccaactacca ctcttccaat gcctaccaca actccaccca tgctgccgac
1621 gtcctgcacg ccaccgcttt ctttcttgga aaggaaagag taaagggaag cctcgatcag
1681 ttggatgagg tggcagccct cattgctgcc acagtccatg acgtggatca cccgggaagg
1741 accaactctt tcctctgcaa tgcaggcagt gagcttgctg tgctctacaa tgacactgct
1801 gttctggaga gtcaccacac cgccctggcc ttccagctca cggtcaagga caccaaatgc
1861 aacattttca agaatattga caggaaccat tatcgaacgc tgcgccaggc tattattgac
1921 atggttttgg caacagagat gacaaaacac tttgaacatg tgaataagtt tgtgaacagc
1981 atcaacaagc caatggcagc tgagattgaa ggcagcgact gtgaatgcaa ccctgctggg
2041 aagaacttcc ctgaaaacca aatcctgatc aaacgcatga tgattaagtg tgctgacgtg
2101 gccaacccat gccgcccctt ggacctgtgc attgaatggg ctgggaggat ctctgaggag
2161 tattttgcac agactgatga agagaagaga cagggactac ctgtggtgat gccagtgttt
2221 gaccggaata cctgtagcat ccccaagtct cagatctctt tcattgacta cttcataaca
2281 gacatgtttg atgcttggga tgcctttgca catctaccag ccctgatgca acatttggct
2341 gacaactaca aacactggaa gacactagat gacctaaagt gcaaaagttt gaggcttcca
2401 tctgacagct aaagccaagc cacagagggg gcctcttgac cgacaaagga cactgtgaat
2461 cacagtagcg taaacaagag gccttccttt ctaatgacaa tgacaggtat tggtgaagga
2521 gctaatgttt aatatttgac cttgaatcat tcaagtcccc aaatttcatt cttagaaagt
2581 tatgttccat gaagaaaaat atatgttctt ttgaatactt aatgacagaa caaatacttg
2641 gcaaactcct ttgctctgct gtcatcctgt gtacccttgt caatccatgg agctggttca
2701 ctgtaactag caggccacag gaagcaaagc cttggtgcct gtgagctcat ctcccaggat
2761 ggtgactaag tagcttagct agtgatcagc tcatccttta ccataaaagt catcattgct
2821 gtttagcttg actgttttcc tcaagaacat cgatctgaag gattcataag gagcttatct
2881 gaacagattt atctaagaaa aaaaaaaaag acataaaata agcgaaacaa ctaggaccaa
2941 attacagata aactagttag cttcacagcc tctatggcta catggttctt ctggccgatg
3001 gtatgacacc taagttagaa cacagccttg gctggtgggt gccctctcta gactggtatc
3061 agcagcctgt gtaacccctt tcctgtaaaa ggggttcatc ttaacaaagt catccatgat
3121 gagggaaaaa gtggcatttc atttttgggg aatccatgag cttcctttat ttctggctca
3181 cagaggcagc cacgaggcac tacaccaagt attatataaa agccattaaa tttgaatgcc
3241 cttggacaag cttttcttaa aaaaaaaaaa aaaaaa
//