LOCUS AY129948 3426 bp mRNA linear HUM 26-JUN-2003
DEFINITION Homo sapiens cAMP-specific phosphodiesterase 8B2 (PDE8B2) mRNA,
complete cds; alternatively spliced.
ACCESSION AY129948
VERSION AY129948.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3426)
AUTHORS Hayashi,M., Shimada,Y., Nishimura,Y., Hama,T. and Tanaka,T.
TITLE Genomic organization, chromosomal localization, and alternative
splicing of the human phosphodiesterase 8B gene
JOURNAL Biochem. Biophys. Res. Commun. 297 (5), 1253-1258 (2002)
PUBMED 12372422
REFERENCE 2 (bases 1 to 3426)
AUTHORS Hayashi,M. and Tanaka,T.
TITLE Direct Submission
JOURNAL Submitted (09-JUL-2002) Molecular and Cellular Pharmacology, Mie
University School of Medicine, 2-174, Edobashi, Tsu, Mie 514-8507,
Japan
FEATURES Location/Qualifiers
source 1..3426
/db_xref="H-InvDB:HIT000250760"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..3426
/gene="PDE8B2"
CDS 46..2562
/gene="PDE8B2"
/note="HSPDE8B2; lacks exon 8; alternatively spliced"
/codon_start=1
/product="cAMP-specific phosphodiesterase 8B2"
/protein_id="AAN71723.1"
/translation="MGCAPSIHVSQSGVIYCRDSDESSSPRQTTSVSQGPAAPLPGLF
VQTDAADAIPPSRASGPPSVARVRRARTELGSGSSAGSAAPAATTSRGRRRHCCSSAE
AETQTCYTSVKQVSSAEVRIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCN
IARTPESALECFLDKHHEIIVIDHRQTQNFDAEAVCRSIRATNPSEHTVILAVVSRVS
DDHEEASVLPLLHAGFNRRFMENSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALD
HCHEAIEITSDDHVIQEWQGVYYARRKSGDSIQQHVKITPVIGQGGKIRHFVSLKKLC
CTTDNNKQIHKIHRDSGDNSQTEPHSFRYKNRRKESIDVKSISSRGSDAPSLQNRRYP
SMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLEILRTTELYSPQLGTKDE
DPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHLAMPITINDVPPCISQLLDNEE
SWDFNIFELEAITHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAWFQVIEANYHSSNA
YHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHPGRTNSFLCNAG
SELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQAIIDMVLATEM
TKHFEHVNKFVNSINKPMAAEIEGSDCECNPAGKNFPENQILIKRMMIKCADVANPCR
PLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMF
DAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSLRLPSDS"
BASE COUNT 945 a 857 c 828 g 796 t
ORIGIN
1 gcggccgcgg gcgcgggcgg gcgcgcgggg gagcccggcc gagggatggg ctgcgccccc
61 agcatccatg tctcgcagag cggcgtgatc tactgccggg actcggacga gtccagctcg
121 ccccgccaga ccaccagcgt gtcgcagggc ccggcggcac ccctgcccgg cctcttcgtc
181 cagaccgacg ccgccgacgc catccccccg agccgcgcgt cgggaccccc cagcgtagcc
241 cgcgtccgca gggcccgcac cgagctgggc agcggtagca gcgcgggttc cgcagccccc
301 gccgcgacca ccagcagggg ccggaggcgc cactgctgca gcagcgccga ggccgagact
361 cagacctgct acaccagcgt gaagcaggtg tcttctgcgg aggtgcgcat cgggcccatg
421 agactgacgc aggaccctat tcaggttttg ctgatctttg caaaggaaga tagtcagagc
481 gatggcttct ggtgggcctg cgacagagct ggttatagat gcaatattgc tcggactcca
541 gagtcagccc ttgaatgctt tcttgataag catcatgaaa ttattgtaat tgatcataga
601 caaactcaga acttcgatgc agaagcagtg tgcaggtcga tccgggccac aaatccctcc
661 gagcacacgg tgatcctcgc agtggtttcg cgagtatcgg atgaccatga agaggcgtca
721 gtccttcctc ttctccacgc aggcttcaac aggagattta tggagaatag cagcataatt
781 gcttgctata atgaactgat tcaaatagaa catggggaag ttcgctccca gttcaaatta
841 cgggcctgta attcagtgtt tacagcatta gatcactgtc atgaagccat agaaataaca
901 agcgatgacc acgtgattca ggagtggcag ggggtttact atgccagacg gaaatccggg
961 gacagcatcc aacagcacgt gaagatcacc ccagtgattg gccaaggagg gaaaattagg
1021 cattttgtct cgctcaagaa actgtgttgt accactgaca ataataagca gattcacaag
1081 attcatcgtg attcaggaga taattctcag acagagcctc attcattcag atataagaac
1141 aggaggaaag agtccattga cgtgaaatcg atatcatctc gaggcagtga tgcaccaagc
1201 ctgcagaatc gtcgctatcc gtccatggcg aggatccact ccatgaccat cgaggctccc
1261 atcacaaagg ttataaatat aatcaatgca gcccaagaaa acagcccagt cacagtagcg
1321 gaagccttgg acagagttct agagatttta cggaccacag aactgtactc ccctcagctg
1381 ggtaccaaag atgaagatcc ccacaccagt gatcttgttg gaggcctgat gactgacggc
1441 ttgagaagac tgtcaggaaa cgagtatgtg tttactaaga atgtgcacca gagtcacagt
1501 caccttgcaa tgccaataac catcaatgat gttccccctt gtatctctca attacttgat
1561 aatgaggaga gttgggactt caacatcttt gaattggaag ccattacgca taaaaggcca
1621 ttggtttatc tgggcttaaa ggtcttctct cggtttggag tatgtgagtt tttaaactgt
1681 tctgaaacca ctcttcgggc ctggttccaa gtgatcgaag ccaactacca ctcttccaat
1741 gcctaccaca actccaccca tgctgccgac gtcctgcacg ccaccgcttt ctttcttgga
1801 aaggaaagag taaagggaag cctcgatcag ttggatgagg tggcagccct cattgctgcc
1861 acagtccatg acgtggatca cccgggaagg accaactctt tcctctgcaa tgcaggcagt
1921 gagcttgctg tgctctacaa tgacactgct gttctggaga gtcaccacac cgccctggcc
1981 ttccagctca cggtcaagga caccaaatgc aacattttca agaatattga caggaaccat
2041 tatcgaacgc tgcgccaggc tattattgac atggttttgg caacagagat gacaaaacac
2101 tttgaacatg tgaataagtt tgtgaacagc atcaacaagc caatggcagc tgagattgaa
2161 ggcagcgact gtgaatgcaa ccctgctggg aagaacttcc ctgaaaacca aatcctgatc
2221 aaacgcatga tgattaagtg tgctgacgtg gccaacccat gccgcccctt ggacctgtgc
2281 attgaatggg ctgggaggat ctctgaggag tattttgcac agactgatga agagaagaga
2341 cagggactac ctgtggtgat gccagtgttt gaccggaata cctgtagcat ccccaagtct
2401 cagatctctt tcattgacta cttcataaca gacatgtttg atgcttggga tgcctttgca
2461 catctaccag ccctgatgca acatttggct gacaactaca aacactggaa gacactagat
2521 gacctaaagt gcaaaagttt gaggcttcca tctgacagct aaagccaagc cacagagggg
2581 gcctcttgac cgacaaagga cactgtgaat cacagtagcg taaacaagag gccttccttt
2641 ctaatgacaa tgacaggtat tggtgaagga gctaatgttt aatatttgac cttgaatcat
2701 tcaagtcccc aaatttcatt cttagaaagt tatgttccat gaagaaaaat atatgttctt
2761 ttgaatactt aatgacagaa caaatacttg gcaaactcct ttgctctgct gtcatcctgt
2821 gtacccttgt caatccatgg agctggttca ctgtaactag caggccacag gaagcaaagc
2881 cttggtgcct gtgagctcat ctcccaggat ggtgactaag tagcttagct agtgatcagc
2941 tcatccttta ccataaaagt catcattgct gtttagcttg actgttttcc tcaagaacat
3001 cgatctgaag gattcataag gagcttatct gaacagattt atctaagaaa aaaaaaaaag
3061 acataaaata agcgaaacaa ctaggaccaa attacagata aactagttag cttcacagcc
3121 tctatggcta catggttctt ctggccgatg gtatgacacc taagttagaa cacagccttg
3181 gctggtgggt gccctctcta gactggtatc agcagcctgt gtaacccctt tcctgtaaaa
3241 ggggttcatc ttaacaaagt catccatgat gagggaaaaa gtggcatttc atttttgggg
3301 aatccatgag cttcctttat ttctggctca cagaggcagc cacgaggcac tacaccaagt
3361 attatataaa agccattaaa tttgaatgcc cttggacaag cttttcttaa aaaaaaaaaa
3421 aaaaaa
//