LOCUS AY124190 2554 bp mRNA linear HUM 16-SEP-2002
DEFINITION Homo sapiens mesoderm induction early response 1 N2-beta-i (MIER1)
mRNA, complete cds; alternatively spliced.
ACCESSION AY124190
VERSION AY124190.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2554)
AUTHORS Paterno,G.D., Ding,Z., Lew,Y.Y., Nash,G.W., Mercer,F.C. and
Gillespie,L.L.
TITLE Genomic organization of the human mi-er1 gene and characterization
of alternatively spliced isoforms: regulated use of a facultative
intron determines subcellular localization
JOURNAL Gene 295 (1), 79-88 (2002)
PUBMED 12242014
REFERENCE 2 (bases 1 to 2554)
AUTHORS Paterno,G.D., Ding,Z., Yew,Y.Y., Nash,G.W., Mercer,F.C. and
Gillespie,L.L.
TITLE Direct Submission
JOURNAL Submitted (19-JUN-2002) Medicine, Memorial University, Health
Sciences Centre, St. John's, NF A1B 3V6, Canada
FEATURES Location/Qualifiers
source 1..2554
/db_xref="H-InvDB:HIT000084577"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p31.2"
gene 1..2554
/gene="MIER1"
CDS 234..1769
/gene="MIER1"
/note="transcription factor; alternatively spliced"
/codon_start=1
/product="mesoderm induction early response 1 N2-beta-i"
/protein_id="AAM97503.1"
/translation="MLPSVESSSPGGSATSDDHEFDPSADMLVHDFDDERTLEEEEMM
EGETNFSSEIEDLAREGDMPIHELLSLYGYGSTVRLPEEDEEEEEEEEEGEDDEDADN
DDNSGCSGENKEENIKDSSGQEDETQSSNDDPSQSVASQDAQEIIRPRRCKYFDTNSE
VEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPVGICRYKENEKVYENDDQLLWDPEYL
PEDKVIIFLKDASRRTGDEKGVEAIPEGSHIKDNEQALYELVKCNFDTEEALRRLRFN
VKAAREELSVWTEEECRNFEQGLKAYGKDFHLIQANKVRTRSVGECVAFYYMWKKSER
YDFFAQQTRFGKKKYNLHPGVTDYMDRLLDESESAASSRAPSPPPTASNSSNSQSEKE
DGTVSTANQNGVSSNGPGEILNKEEVKVEGLHINGPTGGNKKPLHADMDTNGYETDNL
TTDPKLAHMTARNENDFDEKSERPAKRRRVNSNGKESPGSSEFFQEAVSHGKFEELEN
TDD"
regulatory 2494..2499
/regulatory_class="polyA_signal_sequence"
/gene="MIER1"
BASE COUNT 850 a 401 c 571 g 732 t
ORIGIN
1 ctggaagaag gaggcgggcg gcccgggcct caggcccctc ccaggctctg agtctcccgg
61 ctgcaggcgg attggatggg gcttcttcag gcggtggcgg cagcagcgaa ggtggcggcg
121 gcagcagcgg cagcggctat ggtgtggtcg ctcgattctc ccagtgcctg gctgagtttc
181 ggacgtggtt aagaaccaac tggttgaggt tcaatgcaga caagacggat gtgatgctgc
241 catctgttga atcttcaagt ccaggaggtt cagcaacatc agatgaccat gaatttgatc
301 catcagctga catgctggtt catgattttg atgatgaacg aacattagaa gaggaagaaa
361 tgatggaagg agaaacaaac ttcagctctg aaatagaaga tcttgcaagg gaaggcgaca
421 tgccaattca tgaacttctc agcctttatg gttatggtag tactgttcga ctacctgaag
481 aagatgagga agaggaagaa gaggaagaag aaggtgaaga tgatgaagat gctgataatg
541 atgacaacag tggctgtagt ggggaaaata aagaggagaa tataaaggat tcatcaggtc
601 aggaggatga aactcagtct tccaatgatg atccatcaca atctgttgct tctcaagatg
661 cccaggaaat aatccgccca cgtcgatgta aatattttga tacaaatagt gaagtagaag
721 aagaatctga agaagatgaa gattatattc catcagaaga ctggaaaaag gagattatgg
781 tgggctccat gtttcaagca gaaattccag ttggcatttg tagatacaaa gaaaatgaaa
841 aagtatatga aaatgatgat cagctcctgt gggaccctga gtacttacca gaagataaag
901 tgattatatt tcttaaagat gcatctagaa gaacaggtga tgagaagggt gtagaagcaa
961 ttcctgaagg atctcacata aaagacaatg aacaggcttt atatgaattg gttaaatgca
1021 attttgatac agaagaagca ttgagaagat taagatttaa tgtaaaagca gctagagagg
1081 aattatctgt ttggacagag gaagagtgta gaaattttga acaagggctg aaggcctatg
1141 gaaaggattt tcatttgatt caggctaata aagtccgaac aaggtcagtt ggtgaatgtg
1201 tagcattcta ttacatgtgg aaaaaatctg aacgttatga tttctttgct cagcaaacac
1261 gatttggaaa gaagaaatat aatcttcatc ctggtgtaac ggattacatg gatcgtcttc
1321 tagacgaaag tgaaagtgct gcatctagtc gagcaccatc ccctccccca actgcatcaa
1381 acagtagtaa cagccagtct gagaaagaag atggcactgt aagcactgct aatcaaaatg
1441 gagtgtcatc taatggacca ggtgaaatat taaacaaaga ggaagtaaaa gttgaagggt
1501 tacacattaa tggaccaaca ggtggaaata agaaaccact tcatgcagat atggatacta
1561 atggttatga aacagataac cttaccactg acccaaaact tgcccatatg actgcaagaa
1621 atgaaaatga ttttgatgaa aaaagtgaga gacctgccaa aaggcgaagg gtaaacagca
1681 atggaaaaga aagtccaggt tcttctgaat ttttccaaga agcagtctca catgggaaat
1741 ttgaagaact tgaaaacaca gatgactaaa ttttagacct attttacttt ctttggagta
1801 aattctggtg tgactaaaat tttcagggtt gatgggttac cttaaaaagt tgatttcctt
1861 gaagcagttt gaaaatttga attgagtctt aactttagga aatgaggttt cataattctg
1921 ccttttgcag atttttttta ctttaaagct gtcagactct tttaagggta ttttaaaaat
1981 tagtaaattt gaatgaacta aagatatatc tctaccttct catttgaata tctttagttc
2041 attcagattt actaattttg gtaaatctga atgaactaaa gatgtatctg taccttctca
2101 tttgatgtat taatcataaa atttcactac aaggtaattt ttgcttagtt tgatggatga
2161 atgggaaact caagtccaaa tttctgctta ataccaattt ctctgagttt cttgaaatgt
2221 ctttaaaaca gacatttttc tcaccaaaca gtttgagtat ctttattaag gaaaccctta
2281 cgaatcctga aaattatgct agcatgattt ttttatatat agaagtttaa aaataaacca
2341 ggtcaggttt gtatatgtaa aattgttgac atcaatgatg tctttccata ttcttatctg
2401 ggcttaagaa atacattctg tatttttcca gattctttgt agcctttgaa agatttttac
2461 agtacatatg tcttgactga gctgtccttt cttaatacaa aagcgtgtat aattttctta
2521 acttgtacag ttggtaaact tttatgagag gaat
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