LOCUS AY124187 1729 bp mRNA linear HUM 16-SEP-2002
DEFINITION Homo sapiens mesoderm induction early response 1 N2-alpha (MIER1)
mRNA, complete cds; alternatively spliced.
ACCESSION AY124187
VERSION AY124187.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1729)
AUTHORS Paterno,G.D., Ding,Z., Lew,Y.Y., Nash,G.W., Mercer,F.C. and
Gillespie,L.L.
TITLE Genomic organization of the human mi-er1 gene and characterization
of alternatively spliced isoforms: regulated use of a facultative
intron determines subcellular localization
JOURNAL Gene 295 (1), 79-88 (2002)
PUBMED 12242014
REFERENCE 2 (bases 1 to 1729)
AUTHORS Paterno,G.D., Ding,Z., Yew,Y.Y., Nash,G.W., Mercer,F.C. and
Gillespie,L.L.
TITLE Direct Submission
JOURNAL Submitted (19-JUN-2002) Medicine, Memorial University, Health
Sciences Centre, St. John's, NF A1B 3V6, Canada
FEATURES Location/Qualifiers
source 1..1729
/db_xref="H-InvDB:HIT000084574"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p31.2"
gene 1..1729
/gene="MIER1"
CDS 234..1532
/gene="MIER1"
/note="transcription factor; alternatively spliced"
/codon_start=1
/product="mesoderm induction early response 1 N2-alpha"
/protein_id="AAM97500.1"
/translation="MLPSVESSSPGGSATSDDHEFDPSADMLVHDFDDERTLEEEEMM
EGETNFSSEIEDLAREGDMPIHELLSLYGYGSTVRLPEEDEEEEEEEEEGEDDEDADN
DDNSGCSGENKEENIKDSSGQEDETQSSNDDPSQSVASQDAQEIIRPRRCKYFDTNSE
VEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPVGICRYKENEKVYENDDQLLWDPEYL
PEDKVIIFLKDASRRTGDEKGVEAIPEGSHIKDNEQALYELVKCNFDTEEALRRLRFN
VKAAREELSVWTEEECRNFEQGLKAYGKDFHLIQANKVRTRSVGECVAFYYMWKKSER
YDFFAQQTRFGKKKYNLHPGVTDYMDRLLDESESAASSRAPSPPPTASNSSNSQSEKE
DGTVSTANQNGVSSNGPGILQMLLPVHFSAISSRANAFLK"
regulatory 1698..1703
/regulatory_class="polyA_signal_sequence"
/gene="MIER1"
BASE COUNT 553 a 307 c 427 g 442 t
ORIGIN
1 ctggaagaag gaggcgggcg gcccgggcct caggcccctc ccaggctctg agtctcccgg
61 ctgcaggcgg attggatggg gcttcttcag gcggtggcgg cagcagcgaa ggtggcggcg
121 gcagcagcgg cagcggctat ggtgtggtcg ctcgattctc ccagtgcctg gctgagtttc
181 ggacgtggtt aagaaccaac tggttgaggt tcaatgcaga caagacggat gtgatgctgc
241 catctgttga atcttcaagt ccaggaggtt cagcaacatc agatgaccat gaatttgatc
301 catcagctga catgctggtt catgattttg atgatgaacg aacattagaa gaggaagaaa
361 tgatggaagg agaaacaaac ttcagctctg aaatagaaga tcttgcaagg gaaggcgaca
421 tgccaattca tgaacttctc agcctttatg gttatggtag tactgttcga ctacctgaag
481 aagatgagga agaggaagaa gaggaagaag aaggtgaaga tgatgaagat gctgataatg
541 atgacaacag tggctgtagt ggggaaaata aagaggagaa tataaaggat tcatcaggtc
601 aggaggatga aactcagtct tccaatgatg atccatcaca atctgttgct tctcaagatg
661 cccaggaaat aatccgccca cgtcgatgta aatattttga tacaaatagt gaagtagaag
721 aagaatctga agaagatgaa gattatattc catcagaaga ctggaaaaag gagattatgg
781 tgggctccat gtttcaagca gaaattccag ttggcatttg tagatacaaa gaaaatgaaa
841 aagtatatga aaatgatgat cagctcctgt gggaccctga gtacttacca gaagataaag
901 tgattatatt tcttaaagat gcatctagaa gaacaggtga tgagaagggt gtagaagcaa
961 ttcctgaagg atctcacata aaagacaatg aacaggcttt atatgaattg gttaaatgca
1021 attttgatac agaagaagca ttgagaagat taagatttaa tgtaaaagca gctagagagg
1081 aattatctgt ttggacagag gaagagtgta gaaattttga acaagggctg aaggcctatg
1141 gaaaggattt tcatttgatt caggctaata aagtccgaac aaggtcagtt ggtgaatgtg
1201 tagcattcta ttacatgtgg aaaaaatctg aacgttatga tttctttgct cagcaaacac
1261 gatttggaaa gaagaaatat aatcttcatc ctggtgtaac ggattacatg gatcgtcttc
1321 tagacgaaag tgaaagtgct gcatctagtc gagcaccatc ccctccccca actgcatcaa
1381 acagtagtaa cagccagtct gagaaagaag atggcactgt aagcactgct aatcaaaatg
1441 gagtgtcatc taatggacca ggcatactcc aaatgcttct tccagttcat ttttcagcca
1501 tcagttcaag agccaatgcc tttttaaaat aaagcttctg tggtcttgtt tttaatggct
1561 caactgtctg atgtaattga gtgaaggttt gcactgagaa attagcattc aggccttacc
1621 cccatgaagt attactgtta acatatgttc ggactgcttc ccttcaccaa tgtgaacaac
1681 tttttttccc aaacagtatt aaaagccact ttgcaacact tgacttcat
//